8Q4A
| Outward-facing, open1 proteoliposome complex I at 2.6 A. Initially purified in LMNG. | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Grba, D.N, Hirst, J. | Deposit date: | 2023-08-05 | Release date: | 2024-06-05 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Molecular mechanism of the ischemia-induced regulatory switch in mammalian complex I. Science, 384, 2024
|
|
8Q0Q
| Outward-facing, slack proteoliposome complex I at 3.6 A. Initially purified in DDM | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Grba, D.N, Hirst, J. | Deposit date: | 2023-07-28 | Release date: | 2024-06-05 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Molecular mechanism of the ischemia-induced regulatory switch in mammalian complex I. Science, 384, 2024
|
|
8Q48
| Outward-facing, closed proteoliposome complex I at 2.5 A. Initially purified in LMNG. | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Grba, D.N, Hirst, J. | Deposit date: | 2023-08-05 | Release date: | 2024-06-05 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Molecular mechanism of the ischemia-induced regulatory switch in mammalian complex I. Science, 384, 2024
|
|
8Q45
| Inward-facing, closed proteoliposome complex I at 2.7 A. Initially purified in LMNG. | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Grba, D.N, Hirst, J. | Deposit date: | 2023-08-05 | Release date: | 2024-06-05 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Molecular mechanism of the ischemia-induced regulatory switch in mammalian complex I. Science, 384, 2024
|
|
8Q0M
| Outward-facing, closed proteoliposome complex I at 3.1 A. Initially purified in DDM. | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Grba, D.N, Hirst, J. | Deposit date: | 2023-07-28 | Release date: | 2024-06-05 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Molecular mechanism of the ischemia-induced regulatory switch in mammalian complex I. Science, 384, 2024
|
|
8Q49
| Outward-facing, open2 proteoliposome complex I at 2.6 A. Initially purified in LMNG. | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Grba, D.N, Hirst, J. | Deposit date: | 2023-08-05 | Release date: | 2024-06-05 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Molecular mechanism of the ischemia-induced regulatory switch in mammalian complex I. Science, 384, 2024
|
|
8Q0O
| Outward-facing, open2 proteoliposome complex I at 3.1 A. Initially purified in DDM. | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Grba, D.N, Hirst, J. | Deposit date: | 2023-07-28 | Release date: | 2024-06-05 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Molecular mechanism of the ischemia-induced regulatory switch in mammalian complex I. Science, 384, 2024
|
|
8Q0A
| Inward-facing, closed proteoliposome complex I at 3.1 A. Initially purified in DDM. | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Grba, D.N, Hirst, J. | Deposit date: | 2023-07-28 | Release date: | 2024-06-05 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Molecular mechanism of the ischemia-induced regulatory switch in mammalian complex I. Science, 384, 2024
|
|
8Q0F
| Inward-facing, open2 proteoliposome complex I at 3.1 A. Initially purified in DDM. | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Grba, D.N, Hirst, J. | Deposit date: | 2023-07-28 | Release date: | 2024-06-05 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Molecular mechanism of the ischemia-induced regulatory switch in mammalian complex I. Science, 384, 2024
|
|
8Q0J
| Inward-facing, slack proteoliposome complex I at 3.8 A. Initially purified in DDM. | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Grba, D.N, Hirst, J. | Deposit date: | 2023-07-28 | Release date: | 2024-06-05 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Molecular mechanism of the ischemia-induced regulatory switch in mammalian complex I. Science, 384, 2024
|
|
8Q46
| Inward-facing, open2 proteoliposome complex I at 2.6 A. Initially purified in LMNG. | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Grba, D.N, Hirst, J. | Deposit date: | 2023-08-05 | Release date: | 2024-06-05 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Molecular mechanism of the ischemia-induced regulatory switch in mammalian complex I. Science, 384, 2024
|
|
8Q47
| Inward-facing, open1 proteoliposome complex I at 2.9 A. Initially purified in LMNG. | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Grba, D.N, Hirst, J. | Deposit date: | 2023-08-05 | Release date: | 2024-06-05 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Molecular mechanism of the ischemia-induced regulatory switch in mammalian complex I. Science, 384, 2024
|
|
1D4K
| HIV-1 PROTEASE COMPLEXED WITH A MACROCYCLIC PEPTIDOMIMETIC INHIBITOR | Descriptor: | HIV-1 PROTEASE, N-13-[(10S,13S)-9,12-DIOXO-10-(2-BUTYL)-2-OXA-8,11-DIAZABICYCLO [13.2.2] NONADECA-15,17,18-TRIENE] (2R)-BENZYL-(4S)-HYDROXY-5-AMINOPENTANOIC (1R)-HYDROXY-(2S)-INDANEAMIDE, SULFATE ION | Authors: | Tyndall, J.D, Reid, R.C, Tyssen, D.P, Jardine, D.K, Todd, B, Passmore, M, March, D.R, Pattenden, L.K, Alewood, D, Hu, S.H, Alewood, P.F, Birch, C.J, Martin, J.L, Fairlie, D.P. | Deposit date: | 1999-10-04 | Release date: | 2000-10-11 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Synthesis, stability, antiviral activity, and protease-bound structures of substrate-mimicking constrained macrocyclic inhibitors of HIV-1 protease. J.Med.Chem., 43, 2000
|
|
7XRW
| Solution structure of T. brucei RAP1 | Descriptor: | Repressor activator protein 1 | Authors: | Yang, X, Pan, X.H, Ji, Z.Y, Wong, K.B, Zhang, M.J, Zhao, Y.X. | Deposit date: | 2022-05-12 | Release date: | 2023-03-01 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The RRM-mediated RNA binding activity in T. brucei RAP1 is essential for VSG monoallelic expression. Nat Commun, 14, 2023
|
|
8PKO
| The ERAD misfolded glycoprotein checkpoint complex from Chaetomium thermophilum (EDEM:PDI heterodimer). | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Roversi, P, Hitchman, C.J, Lia, A, Bayo, Y. | Deposit date: | 2023-06-27 | Release date: | 2024-07-10 | Last modified: | 2024-09-25 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | The ERAD misfolded glycoprotein checkpoint complex from Chaetomium thermophilum (EDEM:PDI heterodimer). To Be Published
|
|
5HUZ
| Solution structure of coiled coil domain of myosin binding subunit of myosin light chain phosphatase | Descriptor: | Protein phosphatase 1 regulatory subunit 12A | Authors: | Sharma, A.K, Birrane, G, Anklin, C, Rigby, A.C, Pollak, M, Alper, S.L. | Deposit date: | 2016-01-27 | Release date: | 2016-03-02 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | To be published To Be Published
|
|
1BTO
| |
1BJE
| |
1BOF
| GI-ALPHA-1 BOUND TO GDP AND MAGNESIUM | Descriptor: | GI ALPHA 1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Coleman, D.E, Sprang, S.R. | Deposit date: | 1998-08-04 | Release date: | 1999-01-06 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structures of the G protein Gi alpha 1 complexed with GDP and Mg2+: a crystallographic titration experiment. Biochemistry, 37, 1998
|
|
1CZI
| CHYMOSIN COMPLEX WITH THE INHIBITOR CP-113972 | Descriptor: | CHYMOSIN, CP-113972 (NORSTATINE-S-METHYL CYSTEINE-IODO-PHENYLALANINE-PROLINE) | Authors: | Groves, M.R, Dhanaraj, V, Pitts, J.E, Badasso, M, Hoover, D, Nugent, P, Blundell, T.L. | Deposit date: | 1997-01-15 | Release date: | 1997-04-01 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | A 2.3 A resolution structure of chymosin complexed with a reduced bond inhibitor shows that the active site beta-hairpin flap is rearranged when compared with the native crystal structure. Protein Eng., 11, 1998
|
|
1D6X
| |
7VGX
| Neuropeptide Y Y1 Receptor (NPY1R) in Complex with G Protein and its endogeneous Peptide-Agonist Neuropeptide Y (NPY) | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | Authors: | Park, C, Kim, J, Jeong, H, Kang, H, Bang, I, Choi, H.-J. | Deposit date: | 2021-09-19 | Release date: | 2022-02-23 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural basis of neuropeptide Y signaling through Y1 receptor Nat Commun, 13, 2022
|
|
7VH0
| MT2-remalteon-Gi complex | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, Melatonin receptor type 1B, ... | Authors: | Wang, Q.G, Lu, Q.Y. | Deposit date: | 2021-09-20 | Release date: | 2022-03-02 | Last modified: | 2022-09-14 | Method: | ELECTRON MICROSCOPY (3.46 Å) | Cite: | Structural basis of the ligand binding and signaling mechanism of melatonin receptors. Nat Commun, 13, 2022
|
|
7VGZ
| MT1-remalteon-Gi complex | Descriptor: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Wang, Q.G, Lu, Q.Y. | Deposit date: | 2021-09-20 | Release date: | 2022-03-02 | Last modified: | 2022-09-14 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural basis of the ligand binding and signaling mechanism of melatonin receptors. Nat Commun, 13, 2022
|
|
7VGY
| Melatonin receptor1-2-Iodomelatonin-Gicomplex | Descriptor: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Wang, Q.G, Lu, Q.Y. | Deposit date: | 2021-09-20 | Release date: | 2022-03-02 | Last modified: | 2022-09-14 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis of the ligand binding and signaling mechanism of melatonin receptors. Nat Commun, 13, 2022
|
|