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5ORR
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BU of 5orr by Molmil
Crystal structure of Aurora-A kinase in complex with an allosterically binding fragment
Descriptor: 4-[4-(trifluoromethyl)phenyl]-1,2,3-thiadiazol-5-amine, ADENOSINE-5'-DIPHOSPHATE, Aurora kinase A, ...
Authors:McIntyre, P.J, Collins, P.M, von Delft, F, Bayliss, R.
Deposit date:2017-08-16
Release date:2017-11-01
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Characterization of Three Druggable Hot-Spots in the Aurora-A/TPX2 Interaction Using Biochemical, Biophysical, and Fragment-Based Approaches.
ACS Chem. Biol., 12, 2017
7XF9
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BU of 7xf9 by Molmil
Crystal structure of human bleomycin hydrolase H372A mutant
Descriptor: Bleomycin hydrolase
Authors:Chang, C.Y, Zheng, Y.Z, Huang, S.J, Wang, Y.L, Toh, S.I, Lin, E.C.
Deposit date:2022-04-01
Release date:2022-06-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The Structure-Function Relationship of Human Bleomycin Hydrolase: Mutation of a Cysteine Protease into a Serine Protease.
Chembiochem, 23, 2022
1H9W
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BU of 1h9w by Molmil
Native Dioclea Guianensis seed lectin
Descriptor: CALCIUM ION, MANGANESE (II) ION, SEED LECTIN
Authors:Romero, A, Wah, D.A, Sol, F.G.D, Cavada, B.S, Ramos, M.V, Grangeiro, T.B, Sampaio, A.H, Calvete, J.J.
Deposit date:2001-03-22
Release date:2001-03-23
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of Native and Cd/Cd-Substituted Dioclea Guianensis Seed Lectin. A Novel Manganese-Binding Site and Structural Basis of Dimer-Tetramer Association
J.Mol.Biol., 310, 2001
1L60
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BU of 1l60 by Molmil
ANALYSIS OF THE INTERACTION BETWEEN CHARGED SIDE CHAINS AND THE ALPHA-HELIX DIPOLE USING DESIGNED THERMOSTABLE MUTANTS OF PHAGE T4 LYSOZYME
Descriptor: T4 LYSOZYME
Authors:Nicholson, H, Matthews, B.W.
Deposit date:1991-05-06
Release date:1991-10-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Analysis of the effectiveness of proline substitutions and glycine replacements in increasing the stability of phage T4 lysozyme.
Biopolymers, 32, 1992
7WU7
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BU of 7wu7 by Molmil
Prefoldin-tubulin-TRiC complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Prefoldin subunit 1, Prefoldin subunit 2, ...
Authors:Gestaut, D, Zhao, Y, Park, J, Ma, B, Leitner, A, Collier, M, Pintilie, G, Roh, S.-H, Chiu, W, Frydman, J.
Deposit date:2022-02-07
Release date:2022-12-21
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.85 Å)
Cite:Structural visualization of the tubulin folding pathway directed by human chaperonin TRiC/CCT.
Cell, 185, 2022
1L74
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BU of 1l74 by Molmil
MULTIPLE STABILIZING ALANINE REPLACEMENTS WITHIN ALPHA-HELIX 126-134 OF T4 LYSOZYME HAVE INDEPENDENT, ADDITIVE EFFECTS ON BOTH STRUCTURE AND STABILITY
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
Authors:Zhang, X, Matthews, B.W.
Deposit date:1991-09-23
Release date:1991-10-15
Last modified:2020-07-22
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Multiple alanine replacements within alpha-helix 126-134 of T4 lysozyme have independent, additive effects on both structure and stability.
Protein Sci., 1, 1992
1L56
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BU of 1l56 by Molmil
ANALYSIS OF THE INTERACTION BETWEEN CHARGED SIDE CHAINS AND THE ALPHA-HELIX DIPOLE USING DESIGNED THERMOSTABLE MUTANTS OF PHAGE T4 LYSOZYME
Descriptor: BETA-MERCAPTOETHANOL, T4 LYSOZYME
Authors:Nicholson, H, Matthews, B.W.
Deposit date:1991-05-06
Release date:1991-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Analysis of the effectiveness of proline substitutions and glycine replacements in increasing the stability of phage T4 lysozyme.
Biopolymers, 32, 1992
3TAD
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BU of 3tad by Molmil
Crystal Structure of the Liprin-alpha/Liprin-beta complex
Descriptor: GLYCEROL, Liprin-alpha-2, Liprin-beta-1
Authors:Wei, Z, Zheng, S, Yu, C, Zhang, M.
Deposit date:2011-08-04
Release date:2011-10-12
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Liprin-mediated large signaling complex organization revealed by the liprin-alpha/CASK and liprin-alpha/liprin-beta complex structures
Mol.Cell, 43, 2011
1L73
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BU of 1l73 by Molmil
MULTIPLE STABILIZING ALANINE REPLACEMENTS WITHIN ALPHA-HELIX 126-134 OF T4 LYSOZYME HAVE INDEPENDENT, ADDITIVE EFFECTS ON BOTH STRUCTURE AND STABILITY
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
Authors:Zhang, X, Matthews, B.W.
Deposit date:1991-09-23
Release date:1991-10-15
Last modified:2020-07-22
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Multiple alanine replacements within alpha-helix 126-134 of T4 lysozyme have independent, additive effects on both structure and stability.
Protein Sci., 1, 1992
1HCC
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BU of 1hcc by Molmil
THREE-DIMENSIONAL STRUCTURE OF A COMPLEMENT CONTROL PROTEIN MODULE IN SOLUTION
Descriptor: 16TH COMPLEMENT CONTROL PROTEIN
Authors:Norman, D.G, Barlow, P.B, Campbell, I.D.C.
Deposit date:1990-11-28
Release date:1992-04-15
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Three-dimensional structure of a complement control protein module in solution.
J.Mol.Biol., 219, 1991
4P4O
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BU of 4p4o by Molmil
Crystal structure of Leishmania infantum polymerase beta: Ternary gap complex
Descriptor: 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*GP*TP*AP*T)-3'), DNA (5'-D(P*CP*GP*GP*CP*AP*AP*TP*AP*CP*TP*G)-3'), ...
Authors:Mejia, E, Burak, M, Alonso, A, Larraga, V, Kunkel, T, Bebenek, K, Garcia-Diaz, M.
Deposit date:2014-03-12
Release date:2014-08-06
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.3001 Å)
Cite:Structures of the Leishmania infantum polymerase beta.
DNA Repair (Amst.), 18, 2014
4P4M
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BU of 4p4m by Molmil
Crystal structure of Leishmania infantum polymerase beta: Ternary P/T complex
Descriptor: 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*GP*TP*A)-3'), DNA (5'-D(P*AP*TP*AP*CP*TP*G)-3'), ...
Authors:Mejia, E, Burak, M, Alonso, A, Larraga, V, Kunkel, T.A, Bebenek, K, Garcia-Diaz, M.
Deposit date:2014-03-12
Release date:2014-08-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.9185 Å)
Cite:Structures of the Leishmania infantum polymerase beta.
DNA Repair (Amst.), 18, 2014
2INT
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BU of 2int by Molmil
CRYSTAL STRUCTURE OF RECOMBINANT HUMAN INTERLEUKIN-4
Descriptor: INTERLEUKIN-4
Authors:Walter, M.R, Cook, W.J, Zhao, B.G, Cameron Junior, R, Ealick, S.E, Walter Junior, R.L, Reichert, P, Nagabhushan, T.L, Trotta, P.P, Bugg, C.E.
Deposit date:1993-07-22
Release date:1994-01-31
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structure of recombinant human interleukin-4.
J.Biol.Chem., 267, 1992
2XYL
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BU of 2xyl by Molmil
CELLULOMONAS FIMI XYLANASE/CELLULASE COMPLEXED WITH 2-DEOXY-2-FLUORO-XYLOBIOSE
Descriptor: BETA-1,4-GLYCANASE, beta-D-xylopyranose-(1-4)-2-deoxy-2-fluoro-alpha-D-xylopyranose
Authors:Monem, V, Birsan, C, Warren, R.A.J, Withers, S.G, Rose, D.R.
Deposit date:1997-11-20
Release date:1998-03-18
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Exploring the cellulose/xylan specificity of the beta-1,4-glycanase cex from Cellulomonas fimi through crystallography and mutation.
Biochemistry, 37, 1998
3RH4
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BU of 3rh4 by Molmil
DNA Polymerase Beta with a dideoxy-terminated primer with an incoming ribonucleotide (rCTP)
Descriptor: 5'-D(*CP*CP*GP*AP*CP*GP*CP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(DDG))-3', 5'-D(P*GP*TP*CP*GP*G)-3', ...
Authors:Cavanaugh, N.A, Beard, W.A, Batra, V.K, Perera, L, Pedersen, L.G, Wilson, S.H.
Deposit date:2011-04-11
Release date:2011-07-06
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.918 Å)
Cite:Molecular insights into DNA polymerase deterrents for ribonucleotide insertion.
J.Biol.Chem., 286, 2011
7XG1
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BU of 7xg1 by Molmil
CryoEM structure of type IV-A Csf-crRNA binary complex
Descriptor: Csf1, Csf2, Csf3, ...
Authors:Zhang, J.T, Cui, N, Huang, H.D, Jia, N.
Deposit date:2022-04-02
Release date:2023-08-02
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment
Mol.Cell, 83, 2023
7XFZ
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BU of 7xfz by Molmil
CryoEM structure of type IV-A Csf-crRNAsp14-dsDNA ternary complex
Descriptor: Csf1, Csf2, Csf3, ...
Authors:Zhang, J.T, Cui, N, Huang, H.D, Jia, N.
Deposit date:2022-04-02
Release date:2023-08-09
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment.
Mol.Cell, 83, 2023
7XG2
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BU of 7xg2 by Molmil
CryoEM structure of type IV-A NTS-nicked dsDNA bound Csf-crRNA ternary complex
Descriptor: Csf1, Csf2, Csf3, ...
Authors:Zhang, J.T, Cui, N, Huang, H.D, Jia, N.
Deposit date:2022-04-02
Release date:2023-08-09
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment.
Mol.Cell, 83, 2023
7XIM
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BU of 7xim by Molmil
PROTEIN ENGINEERING OF XYLOSE (GLUCOSE) ISOMERASE FROM ACTINOPLANES MISSOURIENSIS. 1. CRYSTALLOGRAPHY AND SITE-DIRECTED MUTAGENESIS OF METAL BINDING SITES
Descriptor: D-XYLOSE ISOMERASE
Authors:Janin, J.
Deposit date:1992-04-03
Release date:1993-07-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Protein engineering of xylose (glucose) isomerase from Actinoplanes missouriensis. 1. Crystallography and site-directed mutagenesis of metal binding sites.
Biochemistry, 31, 1992
2HHM
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BU of 2hhm by Molmil
STRUCTURE OF INOSITOL MONOPHOSPHATASE, THE PUTATIVE TARGET OF LITHIUM THERAPY
Descriptor: GADOLINIUM ATOM, INOSITOL MONOPHOSPHATASE, SULFATE ION
Authors:Bone, R.
Deposit date:1992-10-20
Release date:1993-10-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of inositol monophosphatase, the putative target of lithium therapy.
Proc.Natl.Acad.Sci.USA, 89, 1992
2WOH
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BU of 2woh by Molmil
Strontium soaked E. coli copper amine oxidase
Descriptor: CALCIUM ION, COPPER (II) ION, PRIMARY AMINE OXIDASE, ...
Authors:Smith, M.A, Pirrat, P, Pearson, A.R, Knowles, P.F, Phillips, S.E.V, McPherson, M.J.
Deposit date:2009-07-23
Release date:2010-05-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Exploring the Roles of the Metal Ions in Escherichia Coli Copper Amine Oxidase.
Biochemistry, 49, 2010
2ONE
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BU of 2one by Molmil
ASYMMETRIC YEAST ENOLASE DIMER COMPLEXED WITH RESOLVED 2'-PHOSPHOGLYCERATE AND PHOSPHOENOLPYRUVATE
Descriptor: 2-PHOSPHOGLYCERIC ACID, ENOLASE, LITHIUM ION, ...
Authors:Lebioda, L.
Deposit date:1997-09-08
Release date:1998-01-14
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Mechanism of enolase: the crystal structure of asymmetric dimer enolase-2-phospho-D-glycerate/enolase-phosphoenolpyruvate at 2.0 A resolution.
Biochemistry, 36, 1997
2WOF
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BU of 2wof by Molmil
EDTA treated E. coli copper amine oxidase
Descriptor: COPPER (II) ION, PRIMARY AMINE OXIDASE, SODIUM ION
Authors:Smith, M.A, Pirrat, P, Pearson, A.R, Knowles, P.F, Phillips, S.E.V, McPherson, M.J.
Deposit date:2009-07-23
Release date:2010-05-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Exploring the Roles of the Metal Ions in Escherichia Coli Copper Amine Oxidase.
Biochemistry, 49, 2010
6XT9
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BU of 6xt9 by Molmil
Subunits BBS 1,4,8,9,18 of the human BBSome complex
Descriptor: BBSome-interacting protein 1, Bardet-Biedl syndrome 1 protein, Bardet-Biedl syndrome 4 protein, ...
Authors:Klink, B.U, Raunser, S, Gatsogiannis, C.
Deposit date:2020-01-15
Release date:2020-01-29
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of the human BBSome core complex.
Elife, 9, 2020
4LA7
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BU of 4la7 by Molmil
X-ray crystal structure of the PYL2-quinabactin-Hab1 ternary complex
Descriptor: ACETATE ION, Abscisic acid receptor PYL2, GLYCEROL, ...
Authors:Peterson, F.C, Volkman, B.F, Cutler, S.R.
Deposit date:2013-06-19
Release date:2013-08-07
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Activation of dimeric ABA receptors elicits guard cell closure, ABA-regulated gene expression, and drought tolerance.
Proc.Natl.Acad.Sci.USA, 110, 2013

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数据于2024-10-16公开中

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