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8SBR
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BU of 8sbr by Molmil
E coli. CTP synthase in complex with CTP (sodium malonate + 20 mM MgCl2)
Descriptor: CTP synthase, CYTIDINE-5'-TRIPHOSPHATE, MALONIC ACID
Authors:Holyoak, T, McLeod, M.J, Tran, N.
Deposit date:2023-04-04
Release date:2023-05-24
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:A metal-dependent conformational change provides a structural basis for the inhibition of CTP synthase by gemcitabine-5'-triphosphate.
Protein Sci., 32, 2023
6LTQ
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BU of 6ltq by Molmil
Crystal structure of pyrrolidone carboxyl peptidase from thermophilic keratin degrading bacterium Fervidobacterium islandicum AW-1 (FiPcp)
Descriptor: GLYCEROL, PENTAETHYLENE GLYCOL, Pyroglutamyl-peptidase I
Authors:Dhanasingh, I, Jin, H.S, Lee, D.W, Lee, S.H.
Deposit date:2020-01-23
Release date:2021-02-10
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure of oxidized pyrrolidone carboxypeptidase from Fervidobacterium islandicum AW-1 reveals unique structural features for thermostability and keratinolysis.
Biochem.Biophys.Res.Commun., 540, 2021
4I1P
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BU of 4i1p by Molmil
Human MALT1 (caspase-IG3) in complex with activity based-probe
Descriptor: ACETATE ION, Mucosa-associated lymphoid tissue lymphoma translocation protein 1, tetrapeptide
Authors:Schlauderer, F, Lammens, K, Hopfner, K.P.
Deposit date:2012-11-21
Release date:2014-07-09
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.403 Å)
Cite:Activity-Based Probes for Detection of Active MALT1 Paracaspase in Immune Cells and Lymphomas.
Chem.Biol., 22, 2015
4PT7
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BU of 4pt7 by Molmil
Structure of initiator
Descriptor: Replication initiator A family protein, SULFATE ION
Authors:Schumacher, M.A.
Deposit date:2014-03-10
Release date:2014-06-25
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Mechanism of staphylococcal multiresistance plasmid replication origin assembly by the RepA protein.
Proc.Natl.Acad.Sci.USA, 111, 2014
4XZ3
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BU of 4xz3 by Molmil
Ca. Korarchaeum cryptofilum dinucleotide forming Acetyl-coenzyme A synthetase 1 (Se-Met derivative) in complex with coenzyme A and Mg-AMPPCP, phosphohistidine segment pointing towards nucleotide binding site
Descriptor: Acyl-CoA synthetase (NDP forming), COENZYME A, MAGNESIUM ION, ...
Authors:Weisse, R.H.-J, Scheidig, A.J.
Deposit date:2015-02-03
Release date:2016-01-27
Last modified:2016-02-10
Method:X-RAY DIFFRACTION (2.398 Å)
Cite:Structure of NDP-forming Acetyl-CoA synthetase ACD1 reveals a large rearrangement for phosphoryl transfer.
Proc.Natl.Acad.Sci.USA, 113, 2016
8A50
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BU of 8a50 by Molmil
Crystal structure of HSF2BP-ALPHA1 tetramer
Descriptor: Heat shock factor 2-binding protein, PHOSPHATE ION
Authors:Miron, S, Legrand, P, Ropars, V, Ghouil, R, Zinn-Justin, S.
Deposit date:2022-06-13
Release date:2023-07-05
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.484 Å)
Cite:BRCA2-HSF2BP oligomeric ring disassembly by BRME1 promotes homologous recombination.
Sci Adv, 9, 2023
2C2K
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BU of 2c2k by Molmil
Crystal structures of caspase-3 in complex with aza-peptide Michael acceptor inhibitors.
Descriptor: AZA-PEPTIDE INHIBITOR (5S, 8R, 11S)-8-(2-CARBOXYETHYL)-5-(CARBOXYMETHYL)-14-(4-ETHOXY-4-OXOBUTANOYL)-11-(1-METHYLETHYL)-3,6,9,12-TETRAOXO-1-PHENYL-2-OXA-4,7,10,13,14-PENTAAZAHEXADECAN -16-OIC ACID, ...
Authors:Ganesan, R, Jelakovic, S, Ekici, O.D, Li, Z.Z, James, K.E, Asgian, J.L, Campbell, A.J, Mikolajczyk, J, Salvesen, G.S, Gruetter, M.G, Powers, J.C.
Deposit date:2005-09-29
Release date:2006-09-20
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Design, Synthesis, and Evaluation of Aza-Peptide Michael Acceptors as Selective and Potent Inhibitors of Caspases-2, -3, -6, -7, -8, -9, and - 10.
J.Med.Chem., 49, 2006
8A3F
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BU of 8a3f by Molmil
Proline Racemase (ProR) from the Gram-positive bacterium Acetoanaerobium sticklandii from isotropic tetragonal data at 3.15 A
Descriptor: PYRROLE-2-CARBOXYLATE, Proline racemase A (AsProR)
Authors:Najmudin, S, Pan, X.-S, McAuley, K.E, Fisher, L.M, Sanderson, M.R.
Deposit date:2022-06-08
Release date:2023-07-05
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Structural and Functional analysis of the Proline Racemase (ProR) from the Gram-positive bacterium Acetoanaerobium sticklandii
To Be Published
2DTX
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BU of 2dtx by Molmil
Structure of Thermoplasma acidophilum aldohexose dehydrogenase (AldT) in complex with D-mannose
Descriptor: Glucose 1-dehydrogenase related protein, SULFATE ION, beta-D-mannopyranose
Authors:Yasutake, Y, Nishiya, Y, Tamura, N, Tamura, T.
Deposit date:2006-07-18
Release date:2007-03-27
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural Insights into Unique Substrate Selectivity of Thermoplasma acidophilumd-Aldohexose Dehydrogenase
J.Mol.Biol., 367, 2007
8J6K
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BU of 8j6k by Molmil
Crystal structure of pro-interleukin-18 and caspase-4 complex
Descriptor: Arginine ADP-riboxanase OspC3, Caspase-4 subunit p10, Caspase-4 subunit p20, ...
Authors:Sun, Q, Hou, Y.J, Ding, J.
Deposit date:2023-04-26
Release date:2023-11-29
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.12 Å)
Cite:Recognition and maturation of IL-18 by caspase-4 noncanonical inflammasome.
Nature, 624, 2023
4XYL
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BU of 4xyl by Molmil
Ca. Korarchaeum cryptofilum ACD1 in complex with coenzyme A
Descriptor: CHLORIDE ION, COENZYME A, alpha subunit of Acyl-CoA synthetase (NDP forming), ...
Authors:Weisse, R.H.-J, Scheidig, A.J.
Deposit date:2015-02-02
Release date:2016-01-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure of NDP-forming Acetyl-CoA synthetase ACD1 reveals a large rearrangement for phosphoryl transfer.
Proc.Natl.Acad.Sci.USA, 113, 2016
8B0I
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BU of 8b0i by Molmil
CryoEM structure of bacterial RapZ.GlmZ complex central to the control of cell envelope biogenesis
Descriptor: GlmZ small regulatory RNA, RNase adapter protein RapZ
Authors:Islam, M.S, Hardwick, H.W, Chirgadze, D.Y, Luisi, B.F.
Deposit date:2022-09-07
Release date:2022-10-05
Last modified:2023-01-25
Method:ELECTRON MICROSCOPY (4.28 Å)
Cite:Structure of a bacterial ribonucleoprotein complex central to the control of cell envelope biogenesis.
Embo J., 42, 2023
8B0J
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BU of 8b0j by Molmil
CryoEM structure of bacterial RNaseE.RapZ.GlmZ complex central to the control of cell envelope biogenesis
Descriptor: GlmZ small RNA, RNase adapter protein RapZ, Ribonuclease E
Authors:Islam, M.S, Hardwick, H.W, Chirgadze, D.Y, Luisi, B.F.
Deposit date:2022-09-07
Release date:2022-10-05
Last modified:2023-01-25
Method:ELECTRON MICROSCOPY (3.99 Å)
Cite:Structure of a bacterial ribonucleoprotein complex central to the control of cell envelope biogenesis.
Embo J., 42, 2023
6PKW
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BU of 6pkw by Molmil
Cryo-EM structure of the zebrafish TRPM2 channel in the apo conformation, processed with C2 symmetry (pseudo C4 symmetry)
Descriptor: Transient receptor potential cation channel subfamily M member 2
Authors:Yin, Y, Wu, M, Hsu, A.L, Borschel, W.F, Borgnia, M.J, Lander, G.C, Lee, S.-Y.
Deposit date:2019-06-30
Release date:2019-08-28
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Visualizing structural transitions of ligand-dependent gating of the TRPM2 channel.
Nat Commun, 10, 2019
8GRX
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BU of 8grx by Molmil
APOE4 receptor in complex with APOE4 NTD
Descriptor: Apolipoprotein E, Leukocyte immunoglobulin-like receptor subfamily A member 6
Authors:Zhou, J, Wang, Y, Huang, G, Shi, Y.
Deposit date:2022-09-02
Release date:2023-07-05
Method:ELECTRON MICROSCOPY (3 Å)
Cite:LilrB3 is a putative cell surface receptor of APOE4.
Cell Res., 33, 2023
7WDL
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BU of 7wdl by Molmil
Fungal immunomodulatory protein FIP-nha
Descriptor: Fungal immunomodulatory protein
Authors:Liu, Y, Bastiaan-Net, S, Zhang, Y, Hoppenbrouwers, T, Xie, Y, Wang, Y, Wei, X, Du, G, Zhang, H, Imam, K.M.S.U, Wichers, H.J, Li, Z.
Deposit date:2021-12-22
Release date:2022-06-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.903 Å)
Cite:Linking the thermostability of FIP-nha (Nectria haematococca) to its structural properties.
Int.J.Biol.Macromol., 213, 2022
2BH8
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BU of 2bh8 by Molmil
Combinatorial Protein 1b11
Descriptor: 1B11
Authors:De Bono, S, Riechmann, L, Girard, E, Williams, R.L, Winter, G.
Deposit date:2005-01-07
Release date:2005-02-07
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A Segment of Cold Shock Protein Directs the Folding of a Combinatorial Protein
Proc.Natl.Acad.Sci.USA, 102, 2005
8IZM
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BU of 8izm by Molmil
Structure of the Mumps Virus L Protein (state2) Bound by Phosphoprotein Tetramer
Descriptor: Phosphoprotein, RNA-directed RNA polymerase L, ZINC ION
Authors:Li, T.H, Shen, Q.T.
Deposit date:2023-04-07
Release date:2024-04-17
Method:ELECTRON MICROSCOPY (3.01 Å)
Cite:Structural insights into mumps virus polymerase complex for coordinating replication and transcription
To Be Published
5JM8
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BU of 5jm8 by Molmil
The structure of ATP-bound aerobactin synthetase IucA from a hypervirulent pathotype of Klebsiella pneumoniae
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Aerobactin synthase IucA, MAGNESIUM ION
Authors:Bailey, D.C, Drake, E.J, Gulick, A.M.
Deposit date:2016-04-28
Release date:2016-06-15
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural and Functional Characterization of Aerobactin Synthetase IucA from a Hypervirulent Pathotype of Klebsiella pneumoniae.
Biochemistry, 55, 2016
6VAG
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BU of 6vag by Molmil
Crystal structure of the oligomerization domain of phosphoprotein from parainfluenza virus 5
Descriptor: GLYCEROL, Phosphoprotein
Authors:Aggarwal, M, Abdella, R, He, Y, Lamb, R.A.
Deposit date:2019-12-17
Release date:2020-02-19
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structure of a paramyxovirus polymerase complex reveals a unique methyltransferase-CTD conformation.
Proc.Natl.Acad.Sci.USA, 117, 2020
6PKV
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BU of 6pkv by Molmil
Cryo-EM structure of the zebrafish TRPM2 channel in the apo conformation, processed with C4 symmetry
Descriptor: Transient receptor potential cation channel subfamily M member 2
Authors:Yin, Y, Wu, M, Hsu, A.L, Borschel, W.F, Borgnia, M.J, Lander, G.C, Lee, S.-Y.
Deposit date:2019-06-30
Release date:2019-08-28
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Visualizing structural transitions of ligand-dependent gating of the TRPM2 channel.
Nat Commun, 10, 2019
4Y8V
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BU of 4y8v by Molmil
Ca. Korarchaeum cryptofilum dinucleotide forming Acetyl-coenzyme A synthetase 1 in complex with ADP and additional ADP bound to phosphate binding site
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, alpha subunit of acetyl-CoA synthetase (NDP forming), ...
Authors:Weisse, R.H.-J, Scheidig, A.J.
Deposit date:2015-02-16
Release date:2016-01-27
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.099 Å)
Cite:Structure of NDP-forming Acetyl-CoA synthetase ACD1 reveals a large rearrangement for phosphoryl transfer.
Proc.Natl.Acad.Sci.USA, 113, 2016
8AX4
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BU of 8ax4 by Molmil
Crystal structure of FMV N in its RNA-free form
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Nucleocapsid protein
Authors:Izhaki-Tavor, L, Yechezkel, I, Dessau, M.
Deposit date:2022-08-30
Release date:2023-04-05
Last modified:2023-06-28
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:RNA Encapsulation Mode and Evolutionary Insights from the Crystal Structure of Emaravirus Nucleoprotein.
Microbiol Spectr, 11, 2023
8E0Y
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BU of 8e0y by Molmil
DAHP (3-deoxy-D-arabinoheptulosonate-7-phosphate) Synthase complexed with DAHP oxime, Pr(III), and Pi in unbound:(bound)2:other Conformations
Descriptor: ACETATE ION, CITRATE ANION, DAHP Oxime, ...
Authors:Berti, P.J, Junop, M.S, Grainger, R.
Deposit date:2022-08-09
Release date:2022-10-12
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Role of Half-of-Sites Reactivity and Inter-Subunit Communications in DAHP Synthase Catalysis and Regulation.
Biochemistry, 61, 2022
4YBZ
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BU of 4ybz by Molmil
Ca. Korarchaeum cryptofilum dinucleotide forming Acetyl-coenzyme A synthetase 1 in complex with ADP and with phosphorylated phosphohistidine segment (site I orientation)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, alpha subunit of Acyl-CoA synthetase (NDP forming), ...
Authors:Weisse, R.H.-J, Scheidig, A.J.
Deposit date:2015-02-19
Release date:2016-01-27
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of NDP-forming Acetyl-CoA synthetase ACD1 reveals a large rearrangement for phosphoryl transfer.
Proc.Natl.Acad.Sci.USA, 113, 2016

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数据于2024-07-17公开中

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