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1KXK
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BU of 1kxk by Molmil
Crystal Structure of a RNA Molecule Containing Domain 5 and 6 of the Yeast ai5g Group II Self-splicing Intron
Descriptor: MAGNESIUM ION, ai5g group II Self-splicing intron
Authors:Zhang, L, Doudna, J.A.
Deposit date:2002-01-31
Release date:2002-03-22
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural insights into group II intron catalysis and branch-site selection.
Science, 295, 2002
2QQP
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BU of 2qqp by Molmil
Crystal Structure of Authentic Providence Virus
Descriptor: CALCIUM ION, RNA (5'-R(*UP*UP*UP*U)-3'), p81
Authors:Speir, J.A, Taylor, D.J, Johnson, J.E.
Deposit date:2007-07-26
Release date:2009-01-20
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Evolution in action: N and C termini of subunits in related T = 4 viruses exchange roles as molecular switches.
Structure, 18, 2010
6IJN
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BU of 6ijn by Molmil
The D295N mutant of the N6-methyl-AMP deaminase from Arabidopsis thaliana complexed with N6m-AMP
Descriptor: Adenosine/AMP deaminase family protein, N6-METHYLADENOSINE-5'-MONOPHOSPHATE
Authors:Xie, W, Jia, Q.
Deposit date:2018-10-10
Release date:2019-02-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Alternative conformation induced by substrate binding for Arabidopsis thalianaN6-methyl-AMP deaminase.
Nucleic Acids Res., 47, 2019
6B1G
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BU of 6b1g by Molmil
Solution structure of TDP-43 N-terminal domain dimer.
Descriptor: TAR DNA-binding protein 43, S48E Mutant, Y4R Mutant
Authors:Naik, M.T, Wang, A, Conicella, A, Fawzi, N.L.
Deposit date:2017-09-18
Release date:2018-02-28
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:A single N-terminal phosphomimic disrupts TDP-43 polymerization, phase separation, and RNA splicing.
EMBO J., 37, 2018
1R5D
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BU of 1r5d by Molmil
X-ray structure of bovine seminal ribonuclease swapping dimer from a new crystal form
Descriptor: Ribonuclease, seminal
Authors:Merlino, A, Vitagliano, L, Sica, F, Zagari, A, Mazzarella, L.
Deposit date:2003-10-10
Release date:2004-04-13
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Population shift vs induced fit: The case of bovine seminal ribonuclease swapping dimer
Biopolymers, 73, 2004
1F60
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BU of 1f60 by Molmil
CRYSTAL STRUCTURE OF THE YEAST ELONGATION FACTOR COMPLEX EEF1A:EEF1BA
Descriptor: ELONGATION FACTOR EEF1A, ELONGATION FACTOR EEF1BA
Authors:Andersen, G.R, Pedersen, L, Valente, L, Kinzy, T.G, Nyborg, J.
Deposit date:2000-06-19
Release date:2000-07-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Structural basis for nucleotide exchange and competition with tRNA in the yeast elongation factor complex eEF1A:eEF1Balpha.
Mol.Cell, 6, 2000
2IJH
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BU of 2ijh by Molmil
Crystal structure analysis of ColE1 ROM mutant F14W
Descriptor: Regulatory protein rop
Authors:Ladner, J.E.
Deposit date:2006-09-29
Release date:2007-10-16
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:New crystal structures of ColE1 Rom and variants resulting from mutation of a surface exposed residue: Implications for RNA-recognition.
Proteins, 72, 2008
2IJJ
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BU of 2ijj by Molmil
Crystal structure analysis of ColE1 ROM mutant F14Y
Descriptor: Regulatory protein rop
Authors:Ladner, J.E.
Deposit date:2006-09-29
Release date:2007-10-16
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:New crystal structures of ColE1 Rom and variants resulting from mutation of a surface exposed residue: Implications for RNA-recognition.
Proteins, 72, 2008
5EUQ
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BU of 5euq by Molmil
Crystal structure of an engineered construct of phosphatidylinositol 4 kinase III beta with a potent and selective inhibitor in complex with GDP loaded Rab11
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Phosphatidylinositol 4-kinase beta, Ras-related protein Rab-11A, ...
Authors:Burke, J.E, Fowler, M.L.
Deposit date:2015-11-19
Release date:2016-02-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Design and Structural Characterization of Potent and Selective Inhibitors of Phosphatidylinositol 4 Kinase III beta.
J.Med.Chem., 59, 2016
2X7K
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BU of 2x7k by Molmil
The crystal structure of PPIL1 in complex with cyclosporine A suggests a binding mode for SKIP
Descriptor: CADMIUM ION, CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 1, ...
Authors:Stegmann, C.M, Luehrmann, R, Wahl, M.C.
Deposit date:2010-03-01
Release date:2010-03-23
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:The Crystal Structure of Ppil1 Bound to Cyclosporine a Suggests a Binding Mode for a Linear Epitope of the Skip Protein.
Plos One, 5, 2010
1R5C
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BU of 1r5c by Molmil
X-ray structure of the complex of Bovine seminal ribonuclease swapping dimer with d(CpA)
Descriptor: 2'-DEOXYCYTIDINE-2'-DEOXYADENOSINE-3',5'-MONOPHOSPHATE, Ribonuclease, seminal
Authors:Merlino, A, Vitagliano, L, Sica, F, Zagari, A, Mazzarella, L.
Deposit date:2003-10-10
Release date:2004-04-13
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Population shift vs induced fit: The case of bovine seminal ribonuclease swapping dimer
Biopolymers, 73, 2004
1R5T
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BU of 1r5t by Molmil
The Crystal Structure of Cytidine Deaminase CDD1, an Orphan C to U editase from Yeast
Descriptor: Cytidine deaminase, ZINC ION
Authors:Xie, K, Sowden, M.P, Dance, G.S.C, Torelli, A.T, Smith, H.C, Wedekind, J.E.
Deposit date:2003-10-13
Release date:2004-05-25
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structure of a yeast RNA-editing deaminase provides insight into the fold and function of activation-induced deaminase and APOBEC-1.
Proc.Natl.Acad.Sci.Usa, 101, 2004
6IJP
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BU of 6ijp by Molmil
The structure of the ADAL-IMP complex
Descriptor: Adenosine/AMP deaminase family protein, INOSINIC ACID, ZINC ION
Authors:Xie, W, Jia, Q.
Deposit date:2018-10-11
Release date:2019-02-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Alternative conformation induced by substrate binding for Arabidopsis thalianaN6-methyl-AMP deaminase.
Nucleic Acids Res., 47, 2019
1L1N
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BU of 1l1n by Molmil
POLIOVIRUS 3C PROTEINASE
Descriptor: Genome polyprotein: Picornain 3C
Authors:Mosimann, S.C, Chernaia, M.M, Sia, S, Plotch, S, James, M.N.G.
Deposit date:2002-02-19
Release date:2002-04-10
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Refined X-ray crystallographic structure of the poliovirus 3C gene product.
J.Mol.Biol., 273, 1997
6IJM
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BU of 6ijm by Molmil
Apo structure of the N6-methyl-AMP Deaminase from Arabidopsis thaliana
Descriptor: Adenosine/AMP deaminase family protein, ZINC ION
Authors:Xie, W, Jia, Q.
Deposit date:2018-10-10
Release date:2019-02-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.016 Å)
Cite:Alternative conformation induced by substrate binding for Arabidopsis thalianaN6-methyl-AMP deaminase.
Nucleic Acids Res., 47, 2019
7R8J
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BU of 7r8j by Molmil
Crystal structure of Pseudooceanicola lipolyticus Argonaute bound to 5' p guide DNA in the presence of Mg2+
Descriptor: Argonaute, DNA (5'-D(*TP*TP*AP*CP*TP*GP*CP*AP*CP*AP*GP*GP*TP*GP*AP*CP*GP*A)-3')
Authors:Shin, Y, Murakami, K.S.
Deposit date:2021-06-26
Release date:2022-07-06
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Programmable RNA targeting by bacterial Argonaute nucleases with unconventional guide binding and cleavage specificity.
Nat Commun, 13, 2022
7R8F
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BU of 7r8f by Molmil
Crystal structure of Pseudooceanicola lipolyticus Argonaute
Descriptor: Argonaute
Authors:Shin, Y, Murakami, K.S.
Deposit date:2021-06-26
Release date:2022-07-06
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (3.16 Å)
Cite:Programmable RNA targeting by bacterial Argonaute nucleases with unconventional guide binding and cleavage specificity.
Nat Commun, 13, 2022
7R8K
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BU of 7r8k by Molmil
Crystal structure of Pseudooceanicola lipolyticus Argonaute (SeMet labeled protein)
Descriptor: Argonaute
Authors:Shin, Y, Murakami, K.S.
Deposit date:2021-06-26
Release date:2022-07-06
Last modified:2022-12-28
Method:X-RAY DIFFRACTION (3.28 Å)
Cite:Programmable RNA targeting by bacterial Argonaute nucleases with unconventional guide binding and cleavage specificity.
Nat Commun, 13, 2022
7R8G
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BU of 7r8g by Molmil
Crystal structure of Pseudooceanicola lipolyticus Argonaute bound to 5' OH guide DNA
Descriptor: Argonaute, DNA (5'-D(*TP*AP*CP*TP*GP*CP*AP*CP*AP*GP*GP*TP*GP*AP*CP*GP*A)-3')
Authors:Shin, Y, Murakami, K.S.
Deposit date:2021-06-26
Release date:2022-07-06
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Programmable RNA targeting by bacterial Argonaute nucleases with unconventional guide binding and cleavage specificity.
Nat Commun, 13, 2022
7R8H
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BU of 7r8h by Molmil
Crystal structure of Pseudooceanicola lipolyticus Argonaute bound to 5' p guide DNA
Descriptor: Argonaute, DNA (5'-D(*TP*TP*AP*CP*TP*GP*CP*AP*CP*AP*GP*GP*TP*GP*AP*CP*GP*A)-3')
Authors:Shin, Y, Murakami, K.S.
Deposit date:2021-06-26
Release date:2022-07-06
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Programmable RNA targeting by bacterial Argonaute nucleases with unconventional guide binding and cleavage specificity.
Nat Commun, 13, 2022
1D6A
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BU of 1d6a by Molmil
STRUCTURE OF POKEWEED ANTIVIRAL PROTEIN COMPLEXED WITH GUANINE
Descriptor: GUANINE, POKEWEED ANTIVIRAL PROTEIN
Authors:Kurinov, I.V, Rajamohan, F, Venkatachalam, T.K, Uckun, F.M.
Deposit date:1999-10-12
Release date:1999-12-16
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:X-ray crystallographic analysis of the structural basis for the interaction of pokeweed antiviral protein with guanine residues of ribosomal RNA.
Protein Sci., 8, 1999
2KXM
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BU of 2kxm by Molmil
Solution NMR Structure of the 27 nucleotide engineered neomycin sensing riboswitch RNA-ribostmycin complex
Descriptor: RIBOSTAMYCIN, RNA (27-MER)
Authors:Duchardt-Ferner, E, Weigand, J.E, Ohlenschlager, O, Schmidtke, S.R, Suess, B, Wohnert, J.
Deposit date:2010-05-10
Release date:2011-04-20
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Highly modular structure and ligand binding by conformational capture in a minimalistic riboswitch.
Angew.Chem.Int.Ed.Engl., 49, 2010
7GQU
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BU of 7gqu by Molmil
Crystal Structure of Werner helicase fragment 517-945 in covalent complex with N-[(E,1S)-1-cyclopropyl-3-methylsulfonylprop-2-enyl]-2-(1,1-difluoroethyl)-4-phenoxypyrimidine-5-carboxamide
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN, GLYCEROL, ...
Authors:Classen, M, Benz, J, Brugger, D, Tagliente, O, Rudolph, M.G.
Deposit date:2023-10-19
Release date:2024-05-01
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Chemoproteomic discovery of a covalent allosteric inhibitor of WRN helicase.
Nature, 629, 2024
5DMA
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BU of 5dma by Molmil
Crystal structure of C-terminal tudor domain in PcrA/UvrD helicase
Descriptor: ATP-dependent DNA helicase PcrA
Authors:Lin, C.L, Dillingham, M, Wigley, D.
Deposit date:2015-09-08
Release date:2016-09-28
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:The structure and function of an RNA polymerase interaction domain in the PcrA/UvrD helicase.
Nucleic Acids Res., 45, 2017
3HD4
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BU of 3hd4 by Molmil
MHV Nucleocapsid Protein NTD
Descriptor: Nucleoprotein
Authors:Giedroc, D.P, Keane, S.C, Dann III, C.E.
Deposit date:2009-05-06
Release date:2009-11-17
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.747 Å)
Cite:Coronavirus N Protein N-Terminal Domain (NTD) Specifically Binds the Transcriptional Regulatory Sequence (TRS) and Melts TRS-cTRS RNA Duplexes.
J.Mol.Biol., 394, 2009

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数据于2024-07-17公开中

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