1DGI
 
 | | Cryo-EM structure of human poliovirus(serotype 1)complexed with three domain CD155 | | Descriptor: | POLIOVIRUS RECEPTOR, VP1, VP2, ... | | Authors: | He, Y, Bowman, V.D, Mueller, S, Bator, C.M, Bella, J, Peng, X, Baker, T.S, Wimmer, E, Kuhn, R.J, Rossmann, M.G. | | Deposit date: | 1999-11-24 | | Release date: | 2000-01-24 | | Last modified: | 2024-02-07 | | Method: | ELECTRON MICROSCOPY (22 Å) | | Cite: | Interaction of the poliovirus receptor with poliovirus.
Proc.Natl.Acad.Sci.USA, 97, 2000
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1DL7
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1DN0
 | | STRUCTURE OF THE FAB FRAGMENT FROM A HUMAN IGM COLD AGGLUTININ | | Descriptor: | IGM-KAPPA COLD AGGLUTININ (HEAVY CHAIN), IGM-KAPPA COLD AGGLUTININ (LIGHT CHAIN) | | Authors: | Cauerhff, A, Braden, B, Carvalho, J.G, Leoni, J, Polikarpov, I, Goldbaum, F. | | Deposit date: | 1999-12-15 | | Release date: | 2001-01-24 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.28 Å) | | Cite: | Three-dimensional structure of the Fab from a human IgM cold agglutinin.
J.Immunol., 165, 2000
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1DQT
 | | THE CRYSTAL STRUCTURE OF MURINE CTLA4 (CD152) | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, CYTOTOXIC T LYMPHOCYTE ASSOCIATED ANTIGEN 4 | | Authors: | Ostrov, D.A, Shi, W, Schwartz, J.C, Almo, S.C, Nathenson, S.G. | | Deposit date: | 2000-01-05 | | Release date: | 2000-10-27 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure of murine CTLA-4 and its role in modulating T cell responsiveness.
Science, 290, 2000
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1DR9
 | | CRYSTAL STRUCTURE OF A SOLUBLE FORM OF B7-1 (CD80) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, T LYMPHOCYTE ACTIVATION ANTIGEN | | Authors: | Ikemizu, S, Jones, E.Y, Stuart, D.I, Davis, S.J. | | Deposit date: | 2000-01-06 | | Release date: | 2000-01-10 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structure and dimerization of a soluble form of B7-1.
Immunity, 12, 2000
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1EEQ
 | | M4L/Y(27D)D/T94H Mutant of LEN | | Descriptor: | KAPPA-4 IMMUNOGLOBULIN (LIGHT CHAIN) | | Authors: | Pokkuluri, P.R, Raffen, R, Dieckman, L, Boogaard, C, Stevens, F.J, Schiffer, M. | | Deposit date: | 2000-02-01 | | Release date: | 2001-02-01 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Increasing protein stability by polar surface residues: domain-wide consequences of interactions within a loop.
Biophys.J., 82, 2002
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1EEU
 | | M4L/Y(27D)D/Q89D/T94H mutant of LEN | | Descriptor: | ISOPROPYL ALCOHOL, KAPPA-4 IMMUNOGLOBULIN (LIGHT CHAIN) | | Authors: | Pokkuluri, P.R, Cai, X, Gu, M, Stevens, F.J, Schiffer, M. | | Deposit date: | 2000-02-03 | | Release date: | 2001-02-03 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Factors contributing to decreased protein stability when aspartic acid residues are in beta-sheet regions.
Protein Sci., 11, 2002
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1EFQ
 | | Q38D mutant of LEN | | Descriptor: | KAPPA-4 IMMUNOGLOBULIN (LIGHT CHAIN), URANYL (VI) ION, ZINC ION | | Authors: | Pokkuluri, P.R, Cai, X, Gu, M, Stevens, F.J, Schiffer, M. | | Deposit date: | 2000-02-09 | | Release date: | 2001-02-09 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Factors contributing to decreased protein stability when aspartic acid residues are in beta-sheet regions.
Protein Sci., 11, 2002
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1EGJ
 | | DOMAIN 4 OF THE BETA COMMON CHAIN IN COMPLEX WITH AN ANTIBODY | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY (HEAVY CHAIN), ANTIBODY (LIGHT CHAIN), ... | | Authors: | Rossjohn, J, McKinstry, W.J, Woodcock, J.M, McClure, B.J, Hercus, T.R, Parker, M.W, Lopez, A.F, Bagley, C.J. | | Deposit date: | 2000-02-15 | | Release date: | 2001-02-15 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structure of the activation domain of the GM-CSF/IL-3/IL-5 receptor common beta-chain bound to an antagonist.
Blood, 95, 2000
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1EJO
 | | FAB FRAGMENT OF NEUTRALISING MONOCLONAL ANTIBODY 4C4 COMPLEXED WITH G-H LOOP FROM FMDV. | | Descriptor: | FMDV PEPTIDE, IGG2A MONOCLONAL ANTIBODY (HEAVY CHAIN), IGG2A MONOCLONAL ANTIBODY (LIGHT CHAIN) | | Authors: | Ochoa, W.F, Kalko, S.G, Gomes, P, Fita, I, Verdaguer, N. | | Deposit date: | 2000-03-03 | | Release date: | 2000-03-22 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | A multiply substituted G-H loop from foot-and-mouth disease virus in complex with a neutralizing antibody: a role for water molecules.
J.Gen.Virol., 81, 2000
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1EK3
 | | KAPPA-4 IMMUNOGLOBULIN VL, REC | | Descriptor: | CALCIUM ION, CHLORIDE ION, KAPPA-4 IMMUNOGLOBULIN LIGHT CHAIN VL | | Authors: | Pokkuluri, P.R, Huang, D.-B, Raffen, R, Stevens, F.J, Schiffer, M. | | Deposit date: | 2000-03-06 | | Release date: | 2001-03-06 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | The Structure of Amyloidogenic Kappa-4 Immunoglobulin VL, REC
To be Published
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1E07
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1ETZ
 | | THE THREE-DIMENSIONAL STRUCTURE OF AN ANTI-SWEETENER FAB, NC10.14, SHOWS THE EXTENT OF STRUCTURAL DIVERSITY IN ANTIGEN RECOGNITION BY IMMUNOGLOBULINS | | Descriptor: | FAB NC10.14 - HEAVY CHAIN, FAB NC10.14 - LIGHT CHAIN, N-(P-CYANOPHENYL)-N'-DIPHENYLMETHYL-GUANIDINE-ACETIC ACID | | Authors: | Guddat, L.W, Shan, L, Broomell, C, Ramsland, P.A, Fan, Z, Anchin, J.M, Linthicum, D.S, Edmundson, A.B. | | Deposit date: | 2000-04-13 | | Release date: | 2000-10-18 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | The three-dimensional structure of a complex of a murine Fab (NC10. 14) with a potent sweetener (NC174): an illustration of structural diversity in antigen recognition by immunoglobulins.
J.Mol.Biol., 302, 2000
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1EZV
 | | STRUCTURE OF THE YEAST CYTOCHROME BC1 COMPLEX CO-CRYSTALLIZED WITH AN ANTIBODY FV-FRAGMENT | | Descriptor: | 5-(3,7,11,15,19,23-HEXAMETHYL-TETRACOSA-2,6,10,14,18,22-HEXAENYL)-2,3-DIMETHOXY-6-METHYL-BENZENE-1,4-DIOL, CYTOCHROME B, CYTOCHROME C1, ... | | Authors: | Hunte, C, Koepke, J, Lange, C, Rossmanith, T, Michel, H. | | Deposit date: | 2000-05-12 | | Release date: | 2001-05-16 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure at 2.3 A resolution of the cytochrome bc(1) complex from the yeast Saccharomyces cerevisiae co-crystallized with an antibody Fv fragment.
Structure Fold.Des., 8, 2000
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1F11
 | | F124 FAB FRAGMENT FROM A MONOCLONAL ANTI-PRES2 ANTIBODY | | Descriptor: | F124 IMMUNOGLOBULIN (IGG1 HEAVY CHAIN), F124 IMMUNOGLOBULIN (KAPPA LIGHT CHAIN) | | Authors: | Saul, F.A, Vulliez-Le Normand, B, Passafiume, M, Riottot, M.M, Bentley, G.A. | | Deposit date: | 2000-05-18 | | Release date: | 2000-08-30 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structure of the Fab fragment from F124, a monoclonal antibody specific for hepatitis B surface antigen.
Acta Crystallogr.,Sect.D, 56, 2000
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1F3D
 | | CATALYTIC ANTIBODY 4B2 IN COMPLEX WITH ITS AMIDINIUM HAPTEN. | | Descriptor: | 2-(4-AMINOBENZYLAMINO)-3,4,5,6-TETRAHYDROPYRIDINIUM, CATALYTIC ANTIBODY 4B2, SULFATE ION | | Authors: | Golinelli-Pimpaneau, B, Goncalves, O, Dintinger, T, Blanchard, D, Knossow, M, Tellier, C. | | Deposit date: | 2000-06-02 | | Release date: | 2000-09-13 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.87 Å) | | Cite: | Structural evidence for a programmed general base in the active site of a catalytic antibody.
Proc.Natl.Acad.Sci.USA, 97, 2000
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1F5W
 | | DIMERIC STRUCTURE OF THE COXSACKIE VIRUS AND ADENOVIRUS RECEPTOR D1 DOMAIN | | Descriptor: | COXSACKIE VIRUS AND ADENOVIRUS RECEPTOR, SULFATE ION | | Authors: | van Raaij, M.J, Chouin, E, van der Zandt, H, Bergelson, J.M, Cusack, S. | | Deposit date: | 2000-06-18 | | Release date: | 2000-11-08 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Dimeric structure of the coxsackievirus and adenovirus receptor D1 domain at 1.7 A resolution.
Structure Fold.Des., 8, 2000
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1F6L
 | | VARIABLE LIGHT CHAIN DIMER OF ANTI-FERRITIN ANTIBODY | | Descriptor: | ANTI-FERRITIN IMMUNOGLOBULIN LIGHT CHAIN | | Authors: | Nymalm, Y, Kravchuk, Z, Salminen, T, Chumanevich, A.A, Dubnovitsky, A.P, Kankare, J, Pentikainen, O, Lehtonen, J, Arosio, P, Martsev, S, Johnson, M.S. | | Deposit date: | 2000-06-22 | | Release date: | 2002-10-23 | | Last modified: | 2018-04-04 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Antiferritin VL homodimer binds human spleen ferritin with high specificity
J.STRUCT.BIOL., 138, 2002
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1F97
 | | SOLUBLE PART OF THE JUNCTION ADHESION MOLECULE FROM MOUSE | | Descriptor: | JUNCTION ADHESION MOLECULE, MAGNESIUM ION | | Authors: | Kostrewa, D, Brockhaus, M, D'Arcy, A, Dale, G, Bazzoni, G, Dejana, E, Winkler, F, Hennig, M. | | Deposit date: | 2000-07-07 | | Release date: | 2001-01-10 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | X-ray structure of junctional adhesion molecule: structural basis for homophilic adhesion via a novel dimerization motif.
EMBO J., 20, 2001
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1E6J
 | | Crystal structure of HIV-1 capsid protein (p24) in complex with Fab13B5 | | Descriptor: | CAPSID PROTEIN P24, IMMUNOGLOBULIN | | Authors: | Berthet-Colominas, C, Monaco, S, Novelli, A, Sibai, G, Mallet, F, Cusack, S. | | Deposit date: | 2000-08-18 | | Release date: | 2000-11-27 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Mutual Conformational Adaptations in Antigen and Antibody Upon Complex Formation between an Fab and HIV-1 Capsid Protein P24
Structure, 8, 2000
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1FO0
 | | MURINE ALLOREACTIVE SCFV TCR-PEPTIDE-MHC CLASS I MOLECULE COMPLEX | | Descriptor: | NATURALLY PROCESSED OCTAPEPTIDE PBM1, PROTEIN (ALLOGENEIC H-2KB MHC CLASS I MOLECULE), PROTEIN (BETA-2 MICROGLOBULIN), ... | | Authors: | Reiser, J.B, Darnault, C, Guimezanes, A, Gregoire, C, Mosser, T, Schmitt-Verhulst, A.-M, Fontecilla-Camps, J.C, Malissen, B, Housset, D, Mazza, G. | | Deposit date: | 2000-08-24 | | Release date: | 2000-10-02 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of a T cell receptor bound to an allogeneic MHC molecule.
Nat.Immunol., 1, 2000
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1G6R
 | | A FUNCTIONAL HOT SPOT FOR ANTIGEN RECOGNITION IN A SUPERAGONIST TCR/MHC COMPLEX | | Descriptor: | ALPHA T CELL RECEPTOR, BETA T CELL RECEPTOR, BETA-2 MICROGLOBULIN, ... | | Authors: | Degano, M, Garcia, K.C, Apostolopoulos, V, Rudolph, M.G, Teyton, L, Wilson, I.A. | | Deposit date: | 2000-11-07 | | Release date: | 2000-11-15 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | A functional hot spot for antigen recognition in a superagonist TCR/MHC complex.
Immunity, 12, 2000
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1G7M
 | | CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME (HEL) COMPLEXED WITH THE MUTANT ANTI-HEL MONOCLONAL ANTIBODY D1.3 (VLW92V) | | Descriptor: | ANTI-HEN EGG WHITE LYSOZYME MONOCLONAL ANTIBODY D1.3, LYSOZYME C | | Authors: | Sundberg, E.J, Urrutia, M, Braden, B.C, Isern, J, Mariuzza, R.A. | | Deposit date: | 2000-11-10 | | Release date: | 2000-11-22 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Estimation of the hydrophobic effect in an antigen-antibody protein-protein interface.
Biochemistry, 39, 2000
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1G7H
 | | CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME (HEL) COMPLEXED WITH THE MUTANT ANTI-HEL MONOCLONAL ANTIBODY D1.3(VLW92A) | | Descriptor: | ANTI-HEN EGG WHITE LYSOZYME MONOCLONAL ANTIBODY D1.3, LYSOZYME C | | Authors: | Sundberg, E.J, Urrutia, M, Braden, B.C, Isern, J, Mariuzza, R.A. | | Deposit date: | 2000-11-10 | | Release date: | 2000-11-22 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Estimation of the hydrophobic effect in an antigen-antibody protein-protein interface.
Biochemistry, 39, 2000
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1G7J
 | | CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME (HEL) COMPLEXED WITH THE MUTANT ANTI-HEL MONOCLONAL ANTIBODY D1.3 (VLW92H) | | Descriptor: | ANTI-HEN EGG WHITE LYSOZYME MONOCLONAL ANTIBODY D1.3, LYSOZYME C | | Authors: | Sundberg, E.J, Urrutia, M, Braden, B.C, Isern, J, Mariuzza, R.A. | | Deposit date: | 2000-11-10 | | Release date: | 2000-11-22 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Estimation of the hydrophobic effect in an antigen-antibody protein-protein interface.
Biochemistry, 39, 2000
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