1ETZ
THE THREE-DIMENSIONAL STRUCTURE OF AN ANTI-SWEETENER FAB, NC10.14, SHOWS THE EXTENT OF STRUCTURAL DIVERSITY IN ANTIGEN RECOGNITION BY IMMUNOGLOBULINS
Summary for 1ETZ
Entry DOI | 10.2210/pdb1etz/pdb |
Related | 1CGS 2CGR |
Descriptor | FAB NC10.14 - LIGHT CHAIN, FAB NC10.14 - HEAVY CHAIN, N-(P-CYANOPHENYL)-N'-DIPHENYLMETHYL-GUANIDINE-ACETIC ACID, ... (4 entities in total) |
Functional Keywords | anti-sweetener fab, antigen-antibody, complex, receptor mimicry, antigen recognition, immune system |
Biological source | Mus musculus (house mouse) More |
Total number of polymer chains | 4 |
Total formula weight | 96036.59 |
Authors | Guddat, L.W.,Shan, L.,Broomell, C.,Ramsland, P.A.,Fan, Z.,Anchin, J.M.,Linthicum, D.S.,Edmundson, A.B. (deposition date: 2000-04-13, release date: 2000-10-18, Last modification date: 2017-10-04) |
Primary citation | Guddat, L.W.,Shan, L.,Broomell, C.,Ramsland, P.A.,Fan, Z.,Anchin, J.M.,Linthicum, D.S.,Edmundson, A.B. The three-dimensional structure of a complex of a murine Fab (NC10. 14) with a potent sweetener (NC174): an illustration of structural diversity in antigen recognition by immunoglobulins. J.Mol.Biol., 302:853-872, 2000 Cited by PubMed: 10993728DOI: 10.1006/jmbi.2000.4083 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
Download full validation report