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4RZL
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DNA recognition domain of the cytosine modification-dependent restriction endonuclease LpnPI
Descriptor: PENTAETHYLENE GLYCOL, Restriction endonuclease LpnPI
Authors:Sasnauskas, G, Tamulaitiene, G, Siksnys, V.
Deposit date:2014-12-22
Release date:2015-06-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure-guided sequence specificity engineering of the modification-dependent restriction endonuclease LpnPI.
Nucleic Acids Res., 43, 2015
8OZE
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cryoEM structure of SPARTA complex dimer high resolution
Descriptor: DNA (5'-D(P*AP*TP*AP*CP*AP*AP*CP*CP*TP*AP*CP*TP*AP*CP*CP*TP*C)-3'), Piwi domain-containing protein, RNA (5'-R(P*UP*GP*AP*GP*GP*UP*AP*GP*UP*AP*GP*GP*UP*UP*GP*UP*AP*UP*AP*G)-3'), ...
Authors:Babatunde, E, Dong, C.N, Xu, H.L, Henning, S.
Deposit date:2023-05-09
Release date:2023-08-16
Last modified:2023-08-23
Method:ELECTRON MICROSCOPY (2.91 Å)
Cite:Activation mechanism of a short argonaute-TIR prokaryotic immune system.
Sci Adv, 9, 2023
8OZI
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BU of 8ozi by Molmil
cryoEM structure of SPARTA complex pre-NAD cleavage
Descriptor: DNA (5'-D(*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Piwi domain-containing protein, ...
Authors:Babatunde, E, Dong, C.N, Xu, H.L, Henning, S.
Deposit date:2023-05-09
Release date:2023-08-16
Last modified:2023-08-23
Method:ELECTRON MICROSCOPY (3.22 Å)
Cite:Activation mechanism of a short argonaute-TIR prokaryotic immune system.
Sci Adv, 9, 2023
8OZG
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cryoEM structure of SPARTA complex Tetramer Post-NAD cleavage-1
Descriptor: DNA (5'-D(*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), MAGNESIUM ION, Piwi domain-containing protein, ...
Authors:Babatunde, E, Dong, C.N, Xu, H.L, Henning, S.
Deposit date:2023-05-09
Release date:2023-08-16
Last modified:2023-08-23
Method:ELECTRON MICROSCOPY (3.37 Å)
Cite:Activation mechanism of a short argonaute-TIR prokaryotic immune system.
Sci Adv, 9, 2023
8OZ6
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BU of 8oz6 by Molmil
cryoEM structure of SPARTA complex ligand-free
Descriptor: DNA (5'-D(*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), Piwi domain-containing protein, RNA (5'-R(P*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3'), ...
Authors:Babatunde, E, Dong, C.N, Xu, H.L, Henning, S.
Deposit date:2023-05-08
Release date:2023-08-16
Last modified:2023-08-23
Method:ELECTRON MICROSCOPY (3.97 Å)
Cite:Activation mechanism of a short argonaute-TIR prokaryotic immune system.
Sci Adv, 9, 2023
8OZF
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BU of 8ozf by Molmil
cryoEM structure of SPARTA complex Tetramer Post-NAD cleavage-2
Descriptor: DNA (5'-D(*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), Piwi domain-containing protein, RNA (5'-R(P*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3'), ...
Authors:Babatunde, E, Dong, C.N, Xu, H.L, Henning, S.
Deposit date:2023-05-09
Release date:2023-08-16
Last modified:2023-08-23
Method:ELECTRON MICROSCOPY (3.73 Å)
Cite:Activation mechanism of a short argonaute-TIR prokaryotic immune system.
Sci Adv, 9, 2023
7ECH
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BU of 7ech by Molmil
Crystal Structure of d(G4C2)2-K in F222 space group
Descriptor: DNA (5'-D(*GP*GP*GP*GP*CP*CP*GP*GP*GP*GP*CP*C)-3'), POTASSIUM ION
Authors:Geng, Y, Liu, C, Cai, Q, Luo, Z, Zhu, G.
Deposit date:2021-03-12
Release date:2021-06-09
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Crystal structure of parallel G-quadruplex formed by the two-repeat ALS- and FTD-related GGGGCC sequence.
Nucleic Acids Res., 49, 2021
3WBM
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BU of 3wbm by Molmil
Crystal Structure of protein-RNA complex
Descriptor: DNA/RNA-binding protein Alba 1, RNA (25-MER)
Authors:Ding, J, Wang, D.C.
Deposit date:2013-05-20
Release date:2013-12-11
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Biochemical and structural insights into RNA binding by Ssh10b, a member of the highly conserved Sac10b protein family in Archaea.
J.Biol.Chem., 289, 2014
7V6V
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BU of 7v6v by Molmil
trimolecular G-quadruplexes consists of a hairpin motif and two short chains
Descriptor: DNA (5'-D(*CP*AP*GP*GP*GP*AP*GP*GP*GP*T)-3'), DNA (5'-D(*TP*GP*GP*GP*A)-3')
Authors:Zhang, N, Jing, H.T, Hu, W.X.
Deposit date:2021-08-20
Release date:2023-02-08
Last modified:2024-05-15
Method:SOLID-STATE NMR
Cite:Conversion to Trimolecular G-Quadruplex by Spontaneous Hoogsteen Pairing-Based Strand Displacement Reaction between Bimolecular G-Quadruplex and Double G-Rich Probes.
J.Am.Chem.Soc., 2023
5W7G
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BU of 5w7g by Molmil
An envelope of a filamentous hyperthermophilic virus carries lipids in a horseshoe conformation
Descriptor: DNA (253-MER), ORF132, ORF140
Authors:Kasson, P, DiMaio, F, Yu, X, Lucas-Staat, S, Krupovic, M, Schouten, S, Prangishvili, D, Egelman, E.
Deposit date:2017-06-19
Release date:2017-07-19
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Model for a novel membrane envelope in a filamentous hyperthermophilic virus.
Elife, 6, 2017
1A83
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BU of 1a83 by Molmil
INTRAMOLECULAR I-MOTIF, NMR, 6 STRUCTURES
Descriptor: DNA (5'-(MCY)CTTTCCTTTACCTTTCC-3')
Authors:Han, X, Leroy, J.L, Gueron, M.
Deposit date:1998-04-01
Release date:1998-06-17
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:An intramolecular i-motif: the solution structure and base-pair opening kinetics of d(5mCCT3CCT3ACCT3CC).
J.Mol.Biol., 278, 1998
1BQJ
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BU of 1bqj by Molmil
CRYSTAL STRUCTURE OF D(ACCCT)
Descriptor: DNA (5'-D(*AP*CP*CP*CP*T)-3')
Authors:Weil, J, Min, T, Yang, C, Wang, S, Sutherland, C, Sinha, N, Kang, C.H.
Deposit date:1998-08-17
Release date:1999-03-18
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Stabilization of the i-motif by intramolecular adenine-adenine-thymine base triple in the structure of d(ACCCT).
Acta Crystallogr.,Sect.D, 55, 1999
7V6E
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BU of 7v6e by Molmil
DREP3
Descriptor: DNAation factor-related protein 3, isoform A
Authors:Lee, S.Y, Park, H.H.
Deposit date:2021-08-20
Release date:2022-08-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Helical filament structure of the DREP3 CIDE domain reveals a unified mechanism of CIDE-domain assembly.
Acta Crystallogr D Struct Biol, 77, 2021
2JPZ
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BU of 2jpz by Molmil
Human telomere DNA quadruplex structure in K+ solution hybrid-2 form
Descriptor: DNA (26-MER)
Authors:Dai, J, Carver, M, Punchihewa, C, Jones, R, Yang, D.
Deposit date:2007-05-25
Release date:2007-12-04
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structure of the Hybrid-2 type intramolecular human telomeric G-quadruplex in K+ solution: insights into structure polymorphism of the human telomeric sequence
Nucleic Acids Res., 35, 2007
3Q0A
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BU of 3q0a by Molmil
X-ray crystal structure of the transcription initiation complex of the N4 mini-vRNAP with P2 promoter: Mismatch complex
Descriptor: DNA (5'-D(*TP*GP*CP*CP*TP*CP*CP*CP*AP*GP*GP*CP*A*GP*TP*CP*AP*AP*AP*AP*GP*AP*AP*GP*CP*GP*GP*AP*GP*CP*TP*TP*CP*TP*TP*C)-3'), GUANOSINE-5'-TRIPHOSPHATE, PHOSPHATE ION, ...
Authors:Murakami, K.S.
Deposit date:2010-12-15
Release date:2011-02-23
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:X-ray crystal structures elucidate the nucleotidyl transfer reaction of transcript initiation using two nucleotides.
Proc.Natl.Acad.Sci.USA, 108, 2011
2KEM
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BU of 2kem by Molmil
Extended structure of citidine deaminase domain of APOBEC3G
Descriptor: DNA dC->dU-editing enzyme APOBEC-3G, ZINC ION
Authors:Harjes, E, Gross, P.J, Chen, K, Lu, Y, Shindo, K, Nowarski, R, Gross, J.D, Kotler, M, Harris, R.S, Matsuo, H.
Deposit date:2009-01-30
Release date:2009-06-02
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:An extended structure of the APOBEC3G catalytic domain suggests a unique holoenzyme model
J.Mol.Biol., 389, 2009
2KN8
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BU of 2kn8 by Molmil
NMR structure of the C-terminal domain of pUL89
Descriptor: DNA cleavage and packaging protein large subunit, UL89
Authors:Couvreux, A, Hantz, S, Marquant, R, Champier, G, Alain, S, Morellet, N, Bouaziz, S.
Deposit date:2009-08-18
Release date:2010-06-09
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Insight into the structure of the pUL89 C-terminal domain of the human cytomegalovirus terminase complex.
Proteins, 78, 2010
6D5F
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BU of 6d5f by Molmil
Cryo-EM reconstruction of membrane-enveloped filamentous virus SFV1 (Sulfolobus filamentous virus 1)
Descriptor: DNA (336-MER), Fimbrial protein
Authors:Wang, F, Osinski, T, Liu, Y, Krupovic, M, Prangishvili, D, Egelman, E.H.
Deposit date:2018-04-19
Release date:2018-08-29
Last modified:2020-01-08
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural conservation in a membrane-enveloped filamentous virus infecting a hyperthermophilic acidophile.
Nat Commun, 9, 2018
3G7E
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BU of 3g7e by Molmil
Crystal structure of E. coli Gyrase B co-complexed with PROP-2-YN-1-YL {[5-(4-PIPERIDIN-1-YL-2-PYRIDIN-3-YL-1,3-THIAZOL-5-YL)-1H-PYRAZOL-3-YL]METHYL}CARBAMATE inhibitor
Descriptor: DNA gyrase subunit B, prop-2-yn-1-yl {[5-(4-piperidin-1-yl-2-pyridin-3-yl-1,3-thiazol-5-yl)-1H-pyrazol-3-yl]methyl}carbamate
Authors:Wei, Y, Charifson, P.
Deposit date:2009-02-09
Release date:2010-02-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Discovery of pyrazolthiazoles as novel and potent inhibitors of bacterial gyrase.
Bioorg.Med.Chem.Lett., 20, 2010
3G7B
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BU of 3g7b by Molmil
Staphylococcus aureus Gyrase B co-complex with METHYL ({5-[4-(4-HYDROXYPIPERIDIN-1-YL)-2-PHENYL-1,3-THIAZOL-5-YL]-1H-PYRAZOL-3-YL}METHYL)CARBAMATE inhibitor
Descriptor: DNA gyrase subunit B, methyl ({5-[4-(4-hydroxypiperidin-1-yl)-2-phenyl-1,3-thiazol-5-yl]-1H-pyrazol-3-yl}methyl)carbamate
Authors:Wei, Y, Charisfon, P.
Deposit date:2009-02-09
Release date:2010-02-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Discovery of pyrazolthiazoles as novel and potent inhibitors of bacterial gyrase.
Bioorg.Med.Chem.Lett., 20, 2010
7YQH
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BU of 7yqh by Molmil
Cryo-EM structure of 8-subunit Smc5/6
Descriptor: DNA repair protein KRE29, E3 SUMO-protein ligase MMS21, Non-structural maintenance of chromosome element 3, ...
Authors:Qian, L, Jun, Z, Xiang, Z, Tong, C, Zhaoning, W, Duo, J, Zhenguo, C, Lanfeng, W.
Deposit date:2022-08-07
Release date:2024-01-31
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (5.6 Å)
Cite:Cryo-EM structures of Smc5/6 in multiple states reveal its assembly and functional mechanisms.
Nat.Struct.Mol.Biol., 2024
8HR1
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BU of 8hr1 by Molmil
Cryo-EM structure of SSX1 bound to the unmodified nucleosome at a resolution of 3.02 angstrom
Descriptor: DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ...
Authors:Zebin, T, Ai, H.S, Ziyu, X, Man, P, Liu, L.
Deposit date:2022-12-14
Release date:2023-09-13
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.02 Å)
Cite:Synovial sarcoma X breakpoint 1 protein uses a cryptic groove to selectively recognize H2AK119Ub nucleosomes.
Nat.Struct.Mol.Biol., 31, 2024
1XU4
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BU of 1xu4 by Molmil
ATPASE IN COMPLEX WITH AMP-PNP, MAGNESIUM AND POTASSIUM CO-F
Descriptor: DNA repair and recombination protein radA, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Wu, Y, Qian, X, He, Y, Moya, I.A, Luo, Y.
Deposit date:2004-10-25
Release date:2004-11-16
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of an ATPase-active form of Rad51 homolog from Methanococcus voltae. Insights into potassium dependence
J.Biol.Chem., 280, 2005
5A6D
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BU of 5a6d by Molmil
Proliferating Cell Nuclear Antigen, PCNA, from Thermococcus gammatolerans
Descriptor: DNA POLYMERASE SLIDING CLAMP
Authors:Venancio-Landeros, A, Cardona-Felix, C.S, Rudino-Pinera, E.
Deposit date:2015-06-25
Release date:2016-07-06
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Cloning, recombinant production and crystallographic structure of Proliferating Cell Nuclear Antigen from radioresistant archaeon Thermococcus gammatolerans.
Biochem Biophys Rep, 8, 2016
2JWQ
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BU of 2jwq by Molmil
G-quadruplex recognition by quinacridines: a SAR, NMR and Biological study
Descriptor: DNA (5'-D(*DTP*DTP*DAP*DGP*DGP*DGP*DT)-3'), N,N'-(dibenzo[b,j][1,7]phenanthroline-2,10-diyldimethanediyl)dipropan-1-amine
Authors:Hounsou, C, Guittat, L, Monchaud, D, Jourdan, M, Saettel, N, Mergny, J.L, Teulade-Fichou, M.
Deposit date:2007-10-23
Release date:2008-03-25
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:G-Quadruplex Recognition by Quinacridines: a SAR, NMR, and Biological Study
ChemMedChem, 2, 2007

224572

数据于2024-09-04公开中

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