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3IIP
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BU of 3iip by Molmil
Evolutionary optimization of computationally designed enzymes: Kemp eliminases of the KE07 series
Descriptor: KE7 R6 3/7F, POLYETHYLENE GLYCOL (N=34)
Authors:Khersonsky, O, Dym, O, Tawfik, D.S.
Deposit date:2009-08-03
Release date:2010-03-02
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Evolutionary Optimization of Computationally Designed Enzymes: Kemp Eliminases of the KE07 Series.
J.Mol.Biol., 396, 2010
2WLH
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BU of 2wlh by Molmil
POTASSIUM CHANNEL FROM MAGNETOSPIRILLUM MAGNETOTACTICUM
Descriptor: CHLORIDE ION, POTASSIUM CHANNEL, POTASSIUM ION
Authors:Clarke, O.B, Caputo, A.T, Smith, B.J, Gulbis, J.M.
Deposit date:2009-06-24
Release date:2010-06-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.28 Å)
Cite:Domain Reorientation and Rotation of an Intracellular Assembly Regulate Conduction in Kir Potassium Channels.
Cell(Cambridge,Mass.), 141, 2010
2WLJ
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BU of 2wlj by Molmil
Potassium channel from Magnetospirillum magnetotacticum
Descriptor: CALCIUM ION, CHLORIDE ION, POTASSIUM CHANNEL, ...
Authors:Clarke, O.B, Caputo, A.T, Smith, B.J, Gulbis, J.M.
Deposit date:2009-06-24
Release date:2010-06-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Domain Reorientation and Rotation of an Intracellular Assembly Regulate Conduction in Kir Potassium Channels.
Cell(Cambridge,Mass.), 141, 2010
4XT1
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BU of 4xt1 by Molmil
Structure of a nanobody-bound viral GPCR bound to human chemokine CX3CL1
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHOLESTEROL, Fractalkine, ...
Authors:Burg, J.S, Jude, K.M, Waghray, D, Garcia, K.C.
Deposit date:2015-01-22
Release date:2015-03-04
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.886 Å)
Cite:Structural biology. Structural basis for chemokine recognition and activation of a viral G protein-coupled receptor.
Science, 347, 2015
4XTO
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BU of 4xto by Molmil
Crystal structure of the light-driven sodium pump KR2 in the pentameric red form, pH 5.6
Descriptor: EICOSANE, SODIUM ION, Sodium pumping rhodopsin
Authors:Gushchin, I, Shevchenko, V, Polovinkin, V, Gordeliy, V.
Deposit date:2015-01-23
Release date:2015-04-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of a light-driven sodium pump.
Nat.Struct.Mol.Biol., 22, 2015
4XWH
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BU of 4xwh by Molmil
Crystal structure of the human N-acetyl-alpha-glucosaminidase
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-N-acetylglucosaminidase, ...
Authors:Birrane, G, Meiyappan, M, Dassier, A.
Deposit date:2015-01-28
Release date:2016-02-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Structural characterization of the alpha-N-acetylglucosaminidase, a key enzyme in the pathogenesis of Sanfilippo syndrome B.
J.Struct.Biol., 205, 2019
4XX8
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BU of 4xx8 by Molmil
Crystal structure of Pro1 deletion mutant of human macrophage migration inhibitory factor
Descriptor: GLYCEROL, Macrophage migration inhibitory factor, SULFATE ION
Authors:Pantouris, G, Lolis, E.
Deposit date:2015-01-30
Release date:2015-09-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:An Analysis of MIF Structural Features that Control Functional Activation of CD74.
Chem.Biol., 22, 2015
4XZ9
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BU of 4xz9 by Molmil
Transaldolase variant E60Q/F132Y from T. acidophilum in complex with DHA Schiff base and G3P
Descriptor: 1,3-PROPANDIOL, ACETATE ION, GLYCEROL, ...
Authors:Sautner, V, Tittmann, K.
Deposit date:2015-02-04
Release date:2015-09-30
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Converting Transaldolase into Aldolase through Swapping of the Multifunctional Acid-Base Catalyst: Common and Divergent Catalytic Principles in F6P Aldolase and Transaldolase.
Biochemistry, 54, 2015
1WKP
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BU of 1wkp by Molmil
Flowering locus t (ft) from arabidopsis thaliana
Descriptor: FLOWERING LOCUS T protein, SULFATE ION
Authors:Miller, D, Banfield, M.J, Winter, V.J, Brady, R.L.
Deposit date:2004-06-01
Release date:2005-06-28
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A divergent external loop confers antagonistic activity on floral regulators FT and TFL1.
Embo J., 25, 2006
7WHG
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BU of 7whg by Molmil
Lokiarchaeota gelsolin (2DGel) bound to two molecules of rabbit actin
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Robinson, R.C, Akil, C.
Deposit date:2021-12-30
Release date:2022-09-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Structural and biochemical evidence for the emergence of a calcium-regulated actin cytoskeleton prior to eukaryogenesis
Commun Biol, 5, 2022
4XTN
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BU of 4xtn by Molmil
Crystal structure of the light-driven sodium pump KR2 in the pentameric red form, pH 4.9
Descriptor: EICOSANE, SODIUM ION, Sodium pumping rhodopsin, ...
Authors:Gushchin, I, Shevchenko, V, Polovinkin, V, Gordeliy, V.
Deposit date:2015-01-23
Release date:2015-04-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of a light-driven sodium pump.
Nat.Struct.Mol.Biol., 22, 2015
8VS5
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BU of 8vs5 by Molmil
Structure of catalytic domain of telomere resolvase, ResT, from Borrelia garinii
Descriptor: Telomere resolvase ResT
Authors:Semper, C, Savchenko, A, Watanabe, N, Center for Structural Biology of Infectious Diseases (CSBID)
Deposit date:2024-01-23
Release date:2024-07-17
Method:X-RAY DIFFRACTION (2.796 Å)
Cite:Structure analysis of the telomere resolvase from the Lyme disease spirochete Borrelia garinii reveals functional divergence of its C-terminal domain.
Nucleic Acids Res., 2024
4XX7
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BU of 4xx7 by Molmil
Crystal structure of M2A mutant of human macrophage migration inhibitory factor
Descriptor: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ...
Authors:Pantouris, G, Lolis, E.
Deposit date:2015-01-29
Release date:2015-09-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:An Analysis of MIF Structural Features that Control Functional Activation of CD74.
Chem.Biol., 22, 2015
6XZU
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BU of 6xzu by Molmil
Complex of C-terminal domain of murine complement C3b with the hC3Nb3 nanobody
Descriptor: Complement C3, nanobody hC3Nb1
Authors:Andersen, G.R, Pedersen, H.
Deposit date:2020-02-05
Release date:2020-08-12
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:A Complement C3-Specific Nanobody for Modulation of the Alternative Cascade Identifies the C-Terminal Domain of C3b as Functional in C5 Convertase Activity.
J Immunol., 205, 2020
1WUY
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BU of 1wuy by Molmil
Crystallographic studies on acyl ureas, a new class of inhibitors of glycogen phosphorylase. Broad specificity of the allosteric site
Descriptor: 4-[3-CHLORO-4-({[(2,4-DICHLOROBENZOYL)AMINO]CARBONYL}AMINO)PHENOXY]BUTANOIC ACID, Glycogen phosphorylase, muscle form, ...
Authors:Oikonomakos, N.G, Kosmopoulou, M.N, Chrysina, E.D, Leonidas, D.D, Klabunde, T, Wendt, K.U, Defossa, E.
Deposit date:2004-12-09
Release date:2005-12-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Crystallographic studies on acyl ureas, a new class of glycogen phosphorylase inhibitors, as potential antidiabetic drugs
Protein Sci., 14, 2005
3KDA
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BU of 3kda by Molmil
Crystal structure of the CFTR inhibitory factor Cif with the H269A mutation
Descriptor: CFTR inhibitory factor (Cif)
Authors:Bahl, C.D, Madden, D.R.
Deposit date:2009-10-22
Release date:2010-01-26
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of the cystic fibrosis transmembrane conductance regulator inhibitory factor Cif reveals novel active-site features of an epoxide hydrolase virulence factor.
J.Bacteriol., 192, 2010
5TUM
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BU of 5tum by Molmil
Crystal structure of tetracycline destructase Tet(56)
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, tetracycline destructase Tet(56)
Authors:Park, J, Tolia, N.H.
Deposit date:2016-11-06
Release date:2017-05-10
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.299 Å)
Cite:Plasticity, dynamics, and inhibition of emerging tetracycline resistance enzymes.
Nat. Chem. Biol., 13, 2017
5U3F
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BU of 5u3f by Molmil
Structure of Mycobacterium tuberculosis IlvE, a branched-chain amino acid transaminase, in complex with D-cycloserine derivative
Descriptor: (5-hydroxy-6-methyl-4-{[(3-oxo-2,3-dihydro-1,2-oxazol-4-yl)amino]methyl}pyridin-3-yl)methyl dihydrogen phosphate, Branched-chain-amino-acid aminotransferase
Authors:Favrot, L, Amorim Franco, T.M, Blanchard, J.S.
Deposit date:2016-12-02
Release date:2017-03-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.695 Å)
Cite:Mechanism-Based Inhibition of the Mycobacterium tuberculosis Branched-Chain Aminotransferase by d- and l-Cycloserine.
ACS Chem. Biol., 12, 2017
3KD2
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BU of 3kd2 by Molmil
Crystal structure of the CFTR inhibitory factor Cif
Descriptor: CFTR inhibitory factor (Cif)
Authors:Bahl, C.D, Madden, D.R.
Deposit date:2009-10-22
Release date:2010-01-26
Last modified:2011-10-12
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the cystic fibrosis transmembrane conductance regulator inhibitory factor Cif reveals novel active-site features of an epoxide hydrolase virulence factor.
J.Bacteriol., 192, 2010
8VJ1
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BU of 8vj1 by Molmil
Structure of C-terminal domain of telomere resolvase, ResT, from Borrelia garinii
Descriptor: Telomere resolvase ResT
Authors:Semper, C, Savchenko, A, Watanabe, N, Center for Structural Biology of Infectious Diseases (CSBID)
Deposit date:2024-01-05
Release date:2024-07-17
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Structure analysis of the telomere resolvase from the Lyme disease spirochete Borrelia garinii reveals functional divergence of its C-terminal domain.
Nucleic Acids Res., 2024
3KEV
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BU of 3kev by Molmil
X-ray crystal structure of a DCUN1 domain-containing protein from Galdieria sulfuraria
Descriptor: ACETATE ION, Galieria sulfuraria DCUN1 domain-containing protein, SULFATE ION
Authors:Burgie, E.S, Bingman, C.A, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG)
Deposit date:2009-10-26
Release date:2009-12-01
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structural architecture of Galdieria sulphuraria DCN1L.
Proteins, 79, 2011
8AF9
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BU of 8af9 by Molmil
Structure of a T4SS effector from Brucella sp.
Descriptor: NyxB, T4SS effector protein from Brucella
Authors:Gueguen-Chaignon, V, Salcedo, S.P, Terradot, L.
Deposit date:2022-07-16
Release date:2023-01-25
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Brucella effectors NyxA and NyxB target SENP3 to modulate the subcellular localisation of nucleolar proteins.
Nat Commun, 14, 2023
5TUF
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BU of 5tuf by Molmil
Crystal structure of tetracycline destructase Tet(50) in complex with anhydrotetracycline
Descriptor: 5A,6-ANHYDROTETRACYCLINE, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, ...
Authors:Park, J, Tolia, N.H.
Deposit date:2016-11-06
Release date:2017-05-10
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Plasticity, dynamics, and inhibition of emerging tetracycline resistance enzymes.
Nat. Chem. Biol., 13, 2017
1PH0
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BU of 1ph0 by Molmil
Non-carboxylic Acid-Containing Inhibitor of PTP1B Targeting the Second Phosphotyrosine Site
Descriptor: 2-{4-[2-(S)-ALLYLOXYCARBONYLAMINO-3-{4-[(2-CARBOXY-PHENYL)-OXALYL-AMINO]-PHENYL}-PROPIONYLAMINO]-BUTOXY}-6-HYDROXY-BENZ OIC ACID METHYL ESTER, Protein-tyrosine phosphatase, non-receptor type 1
Authors:Liu, G, Xin, Z, Liang, H, Abad-Zapatero, C, Hajduk, P, Janowick, D, Szczepankiewicz, B, Pei, Z, Hutchins, C.W, Ballaron, S.J.
Deposit date:2003-05-29
Release date:2003-07-29
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Selective Protein Tyrosine Phosphatase 1B Inhibitors: Targeting the Second Phosphotyrosine Binding Site with Non-Carboxylic Acid-Containing Ligands.
J.Med.Chem., 46, 2003
187L
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BU of 187l by Molmil
SPECIFICITY OF LIGAND BINDING IN A BURIED NON-POLAR CAVITY OF T4 LYSOZYME: LINKAGE OF DYNAMICS AND STRUCTURAL PLASTICITY
Descriptor: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, PARA-XYLENE, ...
Authors:Morton, A, Matthews, B.W.
Deposit date:1995-04-19
Release date:1995-07-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Specificity of ligand binding in a buried nonpolar cavity of T4 lysozyme: linkage of dynamics and structural plasticity.
Biochemistry, 34, 1995

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数据于2024-07-17公开中

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