3AOX
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![BU of 3aox by Molmil](/molmil-images/mine/3aox) | X-ray crystal structure of human anaplastic lymphoma kinase in complex with CH5424802 | Descriptor: | 1,2-ETHANEDIOL, 9-ethyl-6,6-dimethyl-8-[4-(morpholin-4-yl)piperidin-1-yl]-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile, ALK tyrosine kinase receptor | Authors: | Nagel, S, Moertl, M, Jestel, A, Fukami, T.A. | Deposit date: | 2010-10-08 | Release date: | 2011-05-25 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | CH5424802, a selective ALK inhibitor capable of blocking the resistant gatekeeper mutant Cancer Cell, 19, 2011
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3AMO
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![BU of 3amo by Molmil](/molmil-images/mine/3amo) | Time-resolved X-ray Crystal Structure Analysis of Enzymatic Reaction of Copper Amine Oxidase from Arthrobacter globiformis | Descriptor: | COPPER (II) ION, GLYCEROL, Phenylethylamine oxidase, ... | Authors: | Kataoka, M, Oya, H, Tominaga, A, Otsu, M, Okajima, T, Tanizawa, K, Yamaguchi, H. | Deposit date: | 2010-08-20 | Release date: | 2011-11-23 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Detection of the reaction intermediates catalyzed by a copper amine oxidase. J.SYNCHROTRON RADIAT., 18, 2011
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3ANP
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![BU of 3anp by Molmil](/molmil-images/mine/3anp) | Crystal structure of Thermus thermophilus FadR, a TetR familly transcriptional repressor, in complex with lauroyl-CoA. | Descriptor: | DODECYL-COA, LAURIC ACID, Transcriptional repressor, ... | Authors: | Agari, Y, Agari, K, Sakamoto, K, Kuramitsu, S, Shinkai, A. | Deposit date: | 2010-09-06 | Release date: | 2011-03-09 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | TetR-family transcriptional repressor Thermus thermophilus FadR controls fatty acid degradation. Microbiology, 157, 2011
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3AOC
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![BU of 3aoc by Molmil](/molmil-images/mine/3aoc) | |
3AT8
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![BU of 3at8 by Molmil](/molmil-images/mine/3at8) | |
3ATD
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![BU of 3atd by Molmil](/molmil-images/mine/3atd) | |
3AVC
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![BU of 3avc by Molmil](/molmil-images/mine/3avc) | Crystal structures of novel allosteric peptide inhibitors of HIV integrase in the LEDGF binding site | Descriptor: | ACETIC ACID, CHLORIDE ION, Integrase, ... | Authors: | Peat, T.S, Deadman, J.J, Newman, J, Rhodes, D.I. | Deposit date: | 2011-03-02 | Release date: | 2012-01-18 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Crystal structures of novel allosteric peptide inhibitors of HIV integrase identify new interactions at the LEDGF binding site. Chembiochem, 12, 2011
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3AUO
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![BU of 3auo by Molmil](/molmil-images/mine/3auo) | DNA polymerase X from Thermus thermophilus HB8 ternary complex with 1-nt gapped DNA and ddGTP | Descriptor: | 1-nt gapped DNA, 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase beta family (X family), ... | Authors: | Nakane, S, Nakagawa, N, Masui, R, Kuramitsu, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2011-02-11 | Release date: | 2012-01-25 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The structural basis of the kinetic mechanism of a gap-filling X-family DNA polymerase that binds Mg(2+)-dNTP before binding to DNA. J.Mol.Biol., 417, 2012
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3AVK
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![BU of 3avk by Molmil](/molmil-images/mine/3avk) | Crystal structures of novel allosteric peptide inhibitors of HIV integrase in the LEDGF binding site | Descriptor: | ACETIC ACID, CHLORIDE ION, Integrase, ... | Authors: | Peat, T.S, Deadman, J.J, Newman, J, Rhodes, D.I. | Deposit date: | 2011-03-05 | Release date: | 2012-01-18 | Last modified: | 2013-06-19 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal structures of novel allosteric peptide inhibitors of HIV integrase identify new interactions at the LEDGF binding site. Chembiochem, 12, 2011
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3ART
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![BU of 3art by Molmil](/molmil-images/mine/3art) | Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - W275G mutant complex structure with DEQUALINIUM | Descriptor: | Chitinase A, DEQUALINIUM, GLYCEROL | Authors: | Pantoom, S, Vetter, I.R, Prinz, H, Suginta, W. | Deposit date: | 2010-12-09 | Release date: | 2011-04-20 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | Potent family-18 chitinase inhibitors: x-ray structures, affinities, and binding mechanisms J.Biol.Chem., 286, 2011
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3AS5
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![BU of 3as5 by Molmil](/molmil-images/mine/3as5) | MamA AMB-1 P212121 | Descriptor: | MAGNESIUM ION, MamA | Authors: | Zeytuni, N, Davidov, G, Zarivach, R. | Deposit date: | 2010-12-10 | Release date: | 2011-07-20 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Self-recognition mechanism of MamA, a magnetosome-associated TPR-containing protein, promotes complex assembly Proc.Natl.Acad.Sci.USA, 108, 2011
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3ATA
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![BU of 3ata by Molmil](/molmil-images/mine/3ata) | |
3AS8
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![BU of 3as8 by Molmil](/molmil-images/mine/3as8) | MamA MSR-1 P41212 | Descriptor: | Magnetosome protein MamA, SULFATE ION | Authors: | Zeytuni, N, Davidov, G, Zarivach, R. | Deposit date: | 2010-12-10 | Release date: | 2011-07-20 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Self-recognition mechanism of MamA, a magnetosome-associated TPR-containing protein, promotes complex assembly Proc.Natl.Acad.Sci.USA, 108, 2011
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3AVM
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![BU of 3avm by Molmil](/molmil-images/mine/3avm) | Crystal structures of novel allosteric peptide inhibitors of HIV integrase in the LEDGF binding site | Descriptor: | ACETIC ACID, CHLORIDE ION, Integrase, ... | Authors: | Peat, T.S, Deadman, J.J, Newman, J, Rhodes, D.I. | Deposit date: | 2011-03-05 | Release date: | 2012-01-18 | Last modified: | 2013-06-19 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Crystal structures of novel allosteric peptide inhibitors of HIV integrase identify new interactions at the LEDGF binding site. Chembiochem, 12, 2011
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3ASH
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![BU of 3ash by Molmil](/molmil-images/mine/3ash) | MamA D159K mutant 1 | Descriptor: | MamA, SULFATE ION | Authors: | Zeytuni, N, Levin, M, Davidov, G, Zarivach, R. | Deposit date: | 2010-12-11 | Release date: | 2011-07-20 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Self-recognition mechanism of MamA, a magnetosome-associated TPR-containing protein, promotes complex assembly Proc.Natl.Acad.Sci.USA, 108, 2011
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3APF
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![BU of 3apf by Molmil](/molmil-images/mine/3apf) | Crystal structure of human PI3K-gamma in complex with CH5039699 | Descriptor: | 3-[7-(1H-benzimidazol-5-yl)-2-(morpholin-4-yl)-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl]phenol, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, SULFATE ION | Authors: | Nakamura, M, Fukami, T.A, Miyazaki, T, Yoshida, M. | Deposit date: | 2010-10-14 | Release date: | 2011-04-13 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.82 Å) | Cite: | Discovery and biological activity of a novel class I PI3K inhibitor, CH5132799 Bioorg.Med.Chem.Lett., 21, 2011
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3AQI
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![BU of 3aqi by Molmil](/molmil-images/mine/3aqi) | H240A variant of human ferrochelatase | Descriptor: | CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, Ferrochelatase, ... | Authors: | Lanzilotta, W.N, Medlock, A.E, Dailey, T.A, Dailey, H.A. | Deposit date: | 2010-11-03 | Release date: | 2012-01-25 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | H240A variant of human ferrochelatase To be published
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3ASU
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![BU of 3asu by Molmil](/molmil-images/mine/3asu) | |
3AT0
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![BU of 3at0 by Molmil](/molmil-images/mine/3at0) | |
3ATE
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![BU of 3ate by Molmil](/molmil-images/mine/3ate) | |
3ARP
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![BU of 3arp by Molmil](/molmil-images/mine/3arp) | Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - complex structure with DEQUALINIUM | Descriptor: | Chitinase A, DEQUALINIUM, GLYCEROL | Authors: | Pantoom, S, Vetter, I.R, Prinz, H, Suginta, W. | Deposit date: | 2010-12-09 | Release date: | 2011-04-20 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Potent family-18 chitinase inhibitors: x-ray structures, affinities, and binding mechanisms J.Biol.Chem., 286, 2011
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3AS1
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![BU of 3as1 by Molmil](/molmil-images/mine/3as1) | Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - W275G mutant complex structure with chelerythrine | Descriptor: | 1,2-dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium, Chitinase A, GLYCEROL | Authors: | Pantoom, S, Vetter, I.R, Prinz, H, Suginta, W. | Deposit date: | 2010-12-09 | Release date: | 2011-04-20 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Potent family-18 chitinase inhibitors: x-ray structures, affinities, and binding mechanisms J.Biol.Chem., 286, 2011
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3ASV
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![BU of 3asv by Molmil](/molmil-images/mine/3asv) | The Closed form of serine dehydrogenase complexed with NADP+ | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PHOSPHATE ION, Short-chain dehydrogenase/reductase SDR | Authors: | Yamazawa, R, Nakajima, Y, Yoshimoto, T, Ito, K. | Deposit date: | 2010-12-21 | Release date: | 2011-10-12 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of serine dehydrogenase from Escherichia coli: important role of the C-terminal region for closed-complex formation. J.Biochem., 149, 2011
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3ATS
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![BU of 3ats by Molmil](/molmil-images/mine/3ats) | Crystal structure of Rv3168 | Descriptor: | CALCIUM ION, GLYCEROL, MAGNESIUM ION, ... | Authors: | Kim, Y.-G, Kim, S, Nguyen, C.M.T, Kim, K.-J. | Deposit date: | 2011-01-13 | Release date: | 2011-08-03 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Crystal structure of Mycobacterium tuberculosis Rv3168: a putative aminoglycoside antibiotics resistance enzyme Proteins, 79, 2011
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3AV6
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![BU of 3av6 by Molmil](/molmil-images/mine/3av6) | Crystal structure of mouse DNA methyltransferase 1 with AdoMet | Descriptor: | DNA (cytosine-5)-methyltransferase 1, S-ADENOSYLMETHIONINE, ZINC ION | Authors: | Takeshita, K, Suetake, I, Yamashita, E, Suga, M, Narita, H, Nakagawa, A, Tajima, S. | Deposit date: | 2011-02-22 | Release date: | 2011-05-04 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.09 Å) | Cite: | Structural insight into maintenance methylation by mouse DNA methyltransferase 1 (Dnmt1). Proc.Natl.Acad.Sci.USA, 108, 2011
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