4F4O
 
 | | Structure of the Haptoglobin-Haemoglobin Complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Haptoglobin, ... | | Authors: | Andersen, C.B.F, Torvund-Jensen, M, Nielsen, M.J, Oliveira, C.L.P, Hersleth, H.P, Andersen, N.H, Pedersen, J.S, Andersen, G.R, Moestrup, S.K. | | Deposit date: | 2012-05-11 | | Release date: | 2012-08-29 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structure of the haptoglobin-haemoglobin complex.
Nature, 489, 2012
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2NL9
 | | Crystal structure of the Mcl-1:Bim BH3 complex | | Descriptor: | Bcl-2-like protein 11, CHLORIDE ION, FUSION PROTEIN CONSISTING OF Induced myeloid leukemia cell differentiation protein Mcl-1 homolog, ... | | Authors: | Czabotar, P.E, Colman, P.M. | | Deposit date: | 2006-10-19 | | Release date: | 2007-03-27 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Structural insights into the degradation of Mcl-1 induced by BH3 domains.
Proc.Natl.Acad.Sci.USA, 104, 2007
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4FA2
 | | Human P38 alpha Mitogen-Activated Kinase In Complex With SB239063 | | Descriptor: | 1,2-ETHANEDIOL, 4-[3-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]PYRIDINE, BETA-MERCAPTOETHANOL, ... | | Authors: | Grum-Tokars, V.L, Minasov, G, Anderson, W.F, Watterson, D.M. | | Deposit date: | 2012-05-21 | | Release date: | 2013-06-05 | | Last modified: | 2020-01-01 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Development of Novel In Vivo Chemical Probes to Address CNS Protein Kinase Involvement in Synaptic Dysfunction.
Plos One, 8, 2013
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4F9W
 | | Human P38alpha MAPK in Complex with a Novel and Selective Small Molecule Inhibitor | | Descriptor: | 4-[3-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]PYRIDINE, ACETATE ION, BETA-MERCAPTOETHANOL, ... | | Authors: | Grum-Tokars, V.L, Minasov, G, Anderson, W.F, Watterson, D.M. | | Deposit date: | 2012-05-21 | | Release date: | 2013-06-05 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Development of Novel In Vivo Chemical Probes to Address CNS Protein Kinase Involvement in Synaptic Dysfunction.
Plos One, 8, 2013
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1U38
 | | Auto-inhibition Mechanism of X11s/Mints Family Scaffold Proteins Revealed by the Closed Conformation of the Tandem PDZ Domains | | Descriptor: | PVYI, amyloid beta A4 precursor protein-binding, family A, ... | | Authors: | Feng, W, Long, J.-F, Chan, L.-N, He, C, Fu, A, Xia, J, Ip, N.Y, Zhang, M. | | Deposit date: | 2004-07-21 | | Release date: | 2005-07-26 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Autoinhibition of X11/Mint scaffold proteins revealed by the closed conformation of the PDZ tandem
Nat.Struct.Mol.Biol., 12, 2005
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2NBB
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1U5P
 | | Crystal Structure of Repeats 15 and 16 of Chicken Brain Alpha Spectrin | | Descriptor: | PHOSPHATE ION, POTASSIUM ION, Spectrin alpha chain, ... | | Authors: | Kusunoki, H, Minasov, G, MacDonald, R.I, Mondragon, A. | | Deposit date: | 2004-07-28 | | Release date: | 2004-10-19 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Independent Movement, Dimerization and Stability of Tandem Repeats of Chicken Brain alpha-Spectrin
J.Mol.Biol., 344, 2004
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2ELA
 | | Crystal Structure of the PTB domain of human APPL1 | | Descriptor: | Adapter protein containing PH domain, PTB domain and leucine zipper motif 1 | | Authors: | Li, J, Mao, X, Dong, L.Q, Liu, F, Tong, L. | | Deposit date: | 2007-03-27 | | Release date: | 2007-05-29 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal Structures of the BAR-PH and PTB Domains of Human APPL1
Structure, 15, 2007
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2QKS
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2F4O
 | | The Mouse PNGase-HR23 Complex Reveals a Complete Remodulation of the Protein-Protein Interface Compared to its Yeast Orthologs | | Descriptor: | CHLORIDE ION, PHQ-VAL-ALA-ASP-CF0, XP-C repair complementing complex 58 kDa protein, ... | | Authors: | Zhao, G, Zhou, X, Wang, L, Kisker, C, Lennarz, W.J, Schindelin, H. | | Deposit date: | 2005-11-23 | | Release date: | 2006-03-07 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.26 Å) | | Cite: | Structure of the mouse peptide N-glycanase-HR23 complex suggests co-evolution of the endoplasmic reticulum-associated degradation and DNA repair pathways.
J.Biol.Chem., 281, 2006
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2NN2
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2NN6
 | | Structure of the human RNA exosome composed of Rrp41, Rrp45, Rrp46, Rrp43, Mtr3, Rrp42, Csl4, Rrp4, and Rrp40 | | Descriptor: | 3'-5' exoribonuclease CSL4 homolog, Exosome complex exonuclease RRP4, Exosome complex exonuclease RRP40, ... | | Authors: | Lima, C.D. | | Deposit date: | 2006-10-23 | | Release date: | 2006-12-26 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (3.35 Å) | | Cite: | Reconstitution, activities, and structure of the eukaryotic RNA exosome.
Cell(Cambridge,Mass.), 127, 2006
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2NPQ
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2NCN
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2EKO
 | | Solution structure of RUH-073, a Pseudo Chromo Domain from Human cDNA | | Descriptor: | Histone acetyltransferase HTATIP | | Authors: | Ruhul Momen, A.Z.M, Hirota, H, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2007-03-23 | | Release date: | 2007-09-25 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of RUH-073, a Pseudo Chromo Domain from Human cDNA
To be Published
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2MXT
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2DX5
 | | The complex structure between the mouse EAP45-GLUE domain and ubiquitin | | Descriptor: | Ubiquitin, Vacuolar protein sorting protein 36 | | Authors: | Hirano, S, Suzuki, N, Slagsvold, T, Kawasaki, M, Trambaiolo, D, Kato, R, Stenmark, H, Wakatsuki, S. | | Deposit date: | 2006-08-24 | | Release date: | 2006-10-10 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (3.35 Å) | | Cite: | Structural basis of ubiquitin recognition by mammalian Eap45 GLUE domain
Nat.Struct.Mol.Biol., 13, 2006
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2QBW
 | | The crystal structure of PDZ-Fibronectin fusion protein | | Descriptor: | PDZ-Fibronectin fusion protein, Polypeptide | | Authors: | Huang, J, Makabe, K, Koide, A, Koide, S. | | Deposit date: | 2007-06-18 | | Release date: | 2008-04-22 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Design of protein function leaps by directed domain interface evolution.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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2Q9V
 | | Crystal structure of the C890S mutant of the 4th PDZ domain of human membrane associated guanylate kinase | | Descriptor: | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 | | Authors: | Pilka, E.S, Hozjan, V, Kavanagh, K.L, Papagrigoriou, E, Cooper, C, Elkins, J.M, Doyle, D.A, von Delft, F, Sundstrom, M, Arrowsmith, C.A, Weigelt, J, Edwards, A, Oppermann, U, Structural Genomics Consortium (SGC) | | Deposit date: | 2007-06-14 | | Release date: | 2007-06-26 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of the C890S mutant of the 4th PDZ domain of human membrane associated guanylate kinase.
To be Published
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2ED2
 | | Solution Structure of RSGI RUH-069, a GTF2I domain in human cDNA | | Descriptor: | General transcription factor II-I | | Authors: | Doi-Katayama, Y, Hirota, H, Izumi, K, Hayashi, F, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2007-02-14 | | Release date: | 2007-08-14 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of RSGI RUH-069, a GTF2I domain in human cDNA
To be published
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2FSM
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2FST
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1VZ0
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2IV0
 | | Thermal stability of isocitrate dehydrogenase from Archaeoglobus fulgidus studied by crystal structure analysis and engineering of chimers | | Descriptor: | CHLORIDE ION, ISOCITRATE DEHYDROGENASE, ZINC ION | | Authors: | Stokke, R, Karlstrom, M, Yang, N, Leiros, I, Ladenstein, R, Birkeland, N.K, Steen, I.H. | | Deposit date: | 2006-06-08 | | Release date: | 2007-04-17 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Thermal Stability of Isocitrate Dehydrogenase from Archaeoglobus Fulgidus Studied by Crystal Structure Analysis and Engineering of Chimers
Extremophiles, 11, 2007
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8TFP
 | | Fab from C10-S66K antibody in complex with carfentanil | | Descriptor: | Carfentanil, Heavy chain of Fab from C10-S66K antibody, Light chain of Fab from C10-S66K antibody | | Authors: | Pholcharee, T, Wilson, I.A. | | Deposit date: | 2023-07-11 | | Release date: | 2023-08-16 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.78 Å) | | Cite: | An Engineered Human-Antibody Fragment with Fentanyl Pan-Specificity That Reverses Carfentanil-Induced Respiratory Depression.
Acs Chem Neurosci, 14, 2023
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