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5MF9
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BU of 5mf9 by Molmil
Solution structure of the RBM5 OCRE domain in complex with polyproline SmN peptide.
Descriptor: RNA-binding protein 5, Survival motor neuron protein
Authors:Mourao, A, Sattler, M, Bonnal, S, Komal, S, Warner, L, Bordonne, R, Valcarcel, J.
Deposit date:2016-11-17
Release date:2016-12-07
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural basis for the recognition ofspliceosomal SmN B B proteins by theRBM5 OCRE domain in splicing regulation
Elife, 5, 2016
5MFY
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BU of 5mfy by Molmil
RBM5 OCRE domain
Descriptor: RNA-binding protein 5
Authors:Warner, L.R, Mourao, A, Soni, K, Sattler, M.
Deposit date:2016-11-19
Release date:2016-12-07
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Structural basis for the recognition of spliceosomal SmN/B/B' proteins by the RBM5 OCRE domain in splicing regulation.
Elife, 5, 2016
7WNT
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BU of 7wnt by Molmil
RNase J from Mycobacterium tuberculosis
Descriptor: Ribonuclease J, ZINC ION
Authors:Li, J, Bao, L, Hu, J, Zhan, B, Li, Z.
Deposit date:2022-01-19
Release date:2023-01-25
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Structural ans functional study of RNase J from Mycobacterium tuberculosis
To Be Published
5YVI
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BU of 5yvi by Molmil
Crystal structure of Karyopherin beta2 in complex with FUS(456-526)
Descriptor: RNA-binding protein FUS, Transportin-1
Authors:Yoshizawa, T, Fung, H.Y.J, Chook, Y.M.
Deposit date:2017-11-25
Release date:2018-05-16
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites.
Cell, 173, 2018
7LRQ
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BU of 7lrq by Molmil
Crystal structure of human SFPQ/NONO heterodimer, conserved DBHS region
Descriptor: CHLORIDE ION, Non-POU domain-containing octamer-binding protein, Splicing factor, ...
Authors:Marshall, A.C, Bond, C.S, Mohnen, I.
Deposit date:2021-02-17
Release date:2021-05-12
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Paraspeckle subnuclear bodies depend on dynamic heterodimerisation of DBHS RNA-binding proteins via their structured domains.
J.Biol.Chem., 298, 2022
7PRE
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BU of 7pre by Molmil
Solution structure of the NRDI domain of Nab3
Descriptor: HLJ1_G0022400.mRNA.1.CDS.1
Authors:Chaves-Arquero, B, Martinez-Lumbreras, S, Perez-Canadillas, J.M.
Deposit date:2021-09-21
Release date:2022-01-12
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Structural basis of Nrd1-Nab3 heterodimerization.
Life Sci Alliance, 5, 2022
8AS6
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BU of 8as6 by Molmil
Structure of the SFTSV L protein bound to 5' cRNA hook [5' HOOK]
Descriptor: RNA (5'-R(*AP*CP*AP*CP*AP*GP*AP*GP*AP*CP*GP*CP*CP*C)-3'), RNA-dependent RNA-polymerase L protein
Authors:Williams, H.M, Thorkelsson, S.R, Vogel, D, Milewski, M, Busch, C, Cusack, S, Grunewald, K, Quemin, E.R.J, Rosenthal, M.
Deposit date:2022-08-18
Release date:2023-01-18
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural insights into viral genome replication by the severe fever with thrombocytopenia syndrome virus L protein.
Nucleic Acids Res., 51, 2023
8K43
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BU of 8k43 by Molmil
In situ structure of RNA-dependent RNA polymerase in full BAV particles
Descriptor: RNA-directed RNA polymerase (Fragment), VP2
Authors:Li, Z, Cao, S.
Deposit date:2023-07-17
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Cryo-EM structures of Banna virus in multiple states reveal stepwise detachment of viral spikes.
Nat Commun, 15, 2024
6R1I
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BU of 6r1i by Molmil
Structure of porcine Aichi virus polymerase
Descriptor: Genome polyprotein
Authors:Dubankova, A, Boura, E.
Deposit date:2019-03-14
Release date:2019-10-09
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.634 Å)
Cite:Structures of kobuviral and siciniviral polymerases reveal conserved mechanism of picornaviral polymerase activation.
J.Struct.Biol., 208, 2019
5IZH
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BU of 5izh by Molmil
Lassa virus L protein cap-snatching endonuclease. apo form
Descriptor: RNA-directed RNA polymerase L
Authors:Reguera, J, Cusack, S.
Deposit date:2016-03-25
Release date:2016-06-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Comparative Structural and Functional Analysis of Bunyavirus and Arenavirus Cap-Snatching Endonucleases.
Plos Pathog., 12, 2016
8URB
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BU of 8urb by Molmil
Porcine epidemic diarrhea virus complete core polymerase complex
Descriptor: RNA (33-MER), RNA (55-MER), ZINC ION, ...
Authors:Anderson, T.K, Kirchdoerfer, R.N.
Deposit date:2023-10-25
Release date:2023-11-15
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:An alphacoronavirus polymerase structure reveals conserved co-factor functions.
Biorxiv, 2023
7OS2
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BU of 7os2 by Molmil
Cryo-EM structure of Brr2 in complex with Jab1/MPN and C9ORF78
Descriptor: Pre-mRNA-processing-splicing factor 8, Telomere length and silencing protein 1 homolog, U5 small nuclear ribonucleoprotein 200 kDa helicase
Authors:Bergfort, A, Hilal, T, Weber, G, Wahl, M.C.
Deposit date:2021-06-07
Release date:2022-02-23
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:The intrinsically disordered TSSC4 protein acts as a helicase inhibitor, placeholder and multi-interaction coordinator during snRNP assembly and recycling.
Nucleic Acids Res., 50, 2022
7Q81
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BU of 7q81 by Molmil
Crystal structure of the methyltransferase-ribozyme 1, 2'-Selenomethyl-Uridine modified (with 1-methyl-adenosine)
Descriptor: GUANINE, MAGNESIUM ION, RNA 2, ...
Authors:Mieczkowski, M, Hoebartner, C.
Deposit date:2021-11-09
Release date:2022-03-23
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structure and mechanism of the methyltransferase ribozyme MTR1.
Nat.Chem.Biol., 18, 2022
5LR5
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BU of 5lr5 by Molmil
N6-methyladenine is accommodated in a conventional A-U basepair
Descriptor: RNA (5'-R(*GP*GP*(6MZ)P*CP*UP*AP*GP*UP*(CBV)P*C)-3'), SULFATE ION
Authors:Huang, L, Lilley, D.M.J.
Deposit date:2016-08-18
Release date:2017-06-21
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Control of box C/D snoRNP assembly by N(6)-methylation of adenine.
EMBO Rep., 18, 2017
7OM6
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BU of 7om6 by Molmil
Thosea asigna virus RdRP domain in complex with RNA
Descriptor: DI(HYDROXYETHYL)ETHER, RNA (5'-R(P*AP*AP*AP*UP*UP*U)-3'), RNA-dependent RNA polymerase
Authors:Ferrero, D.S, Falqui, M, Verdaguer, N.
Deposit date:2021-05-21
Release date:2021-07-28
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Snapshots of a Non-Canonical RdRP in Action.
Viruses, 13, 2021
7OM7
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BU of 7om7 by Molmil
Thosea asigna virus RdRP domain in complex with RNA and nucleotide UMPNPP
Descriptor: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, DI(HYDROXYETHYL)ETHER, MANGANESE (II) ION, ...
Authors:Ferrero, D.S, Falqui, M, Verdaguer, N.
Deposit date:2021-05-21
Release date:2021-07-28
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Snapshots of a Non-Canonical RdRP in Action.
Viruses, 13, 2021
2LW7
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BU of 2lw7 by Molmil
NMR solution structure of human HisRS splice variant
Descriptor: Histidine--tRNA ligase, cytoplasmic
Authors:Ye, F, Wei, Z, Wu, J, Schimmel, P, Zhang, M.
Deposit date:2012-07-24
Release date:2013-09-04
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:NMR solution structure of human HisRS splice variant
To be Published
6LAS
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BU of 6las by Molmil
the wildtype SAM-VI riboswitch bound to SAM
Descriptor: RNA (55-MER), S-ADENOSYLMETHIONINE, U1 small nuclear ribonucleoprotein A
Authors:Ren, A, Sun, A.
Deposit date:2019-11-13
Release date:2020-01-01
Method:X-RAY DIFFRACTION (2.708 Å)
Cite:SAM-VI riboswitch structure and signature for ligand discrimination.
Nat Commun, 10, 2019
8FCS
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BU of 8fcs by Molmil
Structure of pre-miR-31 reveals an active role in Dicer processing
Descriptor: microRNA 31
Authors:Kotar, A, Ma, S, Keane, S.
Deposit date:2022-12-01
Release date:2023-02-22
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure of pre-miR-31 reveals an active role in Dicer processing.
Biorxiv, 2023
2MXJ
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BU of 2mxj by Molmil
Structural features of a 3' splice site influenza A: 11-nt hairpin
Descriptor: RNA_(11-MER)
Authors:Turner, D.H, Kennedy, S.D, Chen, J.L.
Deposit date:2015-01-06
Release date:2015-05-06
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural features of a 3' splice site in influenza a.
Biochemistry, 54, 2015
6CQC
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BU of 6cqc by Molmil
RNase P protein from Thermotoga maritima in complex with 1-(4-Fluorophenyl)-2-thiourea
Descriptor: 1-(4-fluorophenyl)thiourea, Ribonuclease P protein component, SULFATE ION
Authors:Torres-Larios, A, Madrigal-Carrillo, E.A.
Deposit date:2018-03-14
Release date:2019-03-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Discovery of novel RNase P inhibitors via an activity-binding-structure pipeline
To Be Published
3V53
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BU of 3v53 by Molmil
Crystal structure of human RBM25
Descriptor: RNA-binding protein 25
Authors:Gong, D.S.
Deposit date:2011-12-16
Release date:2012-12-12
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure and functional characterization of the human RBM25 PWI domain and its flanking basic region
Biochem.J., 450, 2013
2MXK
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BU of 2mxk by Molmil
Structural features of a 3' splice site influenza A: 19-nt duplex
Descriptor: RNA (5'-R(*GP*CP*AP*GP*GP*CP*CP*CP*A)-3'), RNA (5'-R(*UP*GP*GP*GP*AP*GP*UP*GP*CP*A)-3')
Authors:Turner, D.H, Kennedy, S.D, Chen, J.L.
Deposit date:2015-01-06
Release date:2015-05-06
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural features of a 3' splice site in influenza a.
Biochemistry, 54, 2015
7POF
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BU of 7pof by Molmil
Structural effects of m6A modification of the Xist A repeat AUCG tetraloop and its recognition by YTHDC1
Descriptor: RNA (5'-R(*GP*GP*CP*GP*CP*(6MZ)P*UP*CP*GP*GP*CP*GP*CP*C)-3')
Authors:Jones, A.N, Sattler, M.
Deposit date:2021-09-08
Release date:2022-03-16
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Structural effects of m6A modification of the Xist A-repeat AUCG tetraloop and its recognition by YTHDC1.
Nucleic Acids Res., 50, 2022
5LW5
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BU of 5lw5 by Molmil
TURNIP YELLOW MOSAIC VIRUS PROTEASE/DEUBIQUITINASE DOMAIN, DELTAC5 MUTANT
Descriptor: RNA replicase polyprotein
Authors:Ayach, M, Bressanelli, S.
Deposit date:2016-09-15
Release date:2017-10-25
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.649 Å)
Cite:A mobile loop near the active site acts as a switch between the dual activities of a viral protease/deubiquitinase.
PLoS Pathog., 13, 2017

223790

数据于2024-08-14公开中

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