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1EYW
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BU of 1eyw by Molmil
THREE-DIMENSIONAL STRUCTURE OF THE ZINC-CONTAINING PHOSPHOTRIESTERASE WITH BOUND SUBSTRATE ANALOG TRIETHYLPHOSPHATE
Descriptor: 2-PHENYL-ETHANOL, PHOSPHOTRIESTERASE, TRIETHYL PHOSPHATE, ...
Authors:Holden, H.M, Benning, M.M, Raushel, F.M, Hong, S.-B.
Deposit date:2000-05-09
Release date:2000-12-20
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The binding of substrate analogs to phosphotriesterase.
J.Biol.Chem., 275, 2000
3E2Q
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BU of 3e2q by Molmil
Crystal Structure Reduced PutA86-630 Mutant Y540S Complexed with trans-4-hydroxy-L-proline
Descriptor: 4-HYDROXYPROLINE, FLAVIN-ADENINE DINUCLEOTIDE, PENTAETHYLENE GLYCOL, ...
Authors:Tanner, J.J.
Deposit date:2008-08-06
Release date:2009-02-03
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:A conserved active site tyrosine residue of proline dehydrogenase helps enforce the preference for proline over hydroxyproline as the substrate.
Biochemistry, 48, 2009
1ENA
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BU of 1ena by Molmil
CRYSTAL STRUCTURES OF THE BINARY CA2+ AND PDTP COMPLEXES AND THE TERNARY COMPLEX OF THE ASP 21->GLU MUTANT OF STAPHYLOCOCCAL NUCLEASE. IMPLICATIONS FOR CATALYSIS AND LIGAND BINDING
Descriptor: CALCIUM ION, STAPHYLOCOCCAL NUCLEASE
Authors:Libson, A, Gittis, A, Lattman, E.E.
Deposit date:1994-02-14
Release date:1994-05-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal structures of the binary Ca2+ and pdTp complexes and the ternary complex of the Asp21-->Glu mutant of staphylococcal nuclease. Implications for catalysis and ligand binding.
Biochemistry, 33, 1994
1ENE
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BU of 1ene by Molmil
1A CRYSTAL STRUCTURES OF B-DNA REVEAL SEQUENCE-SPECIFIC BINDING AND GROOVE-SPECIFIC BENDING OF DNA BY MAGNESIUM AND CALCIUM.
Descriptor: CALCIUM ION, DNA (5'-D(*CP*CP*AP*GP*CP*GP*CP*TP*GP*G)-3'), ETHANOL
Authors:Chiu, T.K, Dickerson, R.E.
Deposit date:2000-03-21
Release date:2000-09-25
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (0.985 Å)
Cite:1 A crystal structures of B-DNA reveal sequence-specific binding and groove-specific bending of DNA by magnesium and calcium.
J.Mol.Biol., 301, 2000
1EPS
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BU of 1eps by Molmil
STRUCTURE AND TOPOLOGICAL SYMMETRY OF THE GLYPHOSPHATE 5-ENOL-PYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE: A DISTINCTIVE PROTEIN FOLD
Descriptor: 5-ENOL-PYRUVYL-3-PHOSPHATE SYNTHASE
Authors:Stallings, W.C, Abdel-Meguid, S.S, Lim, L.W, Shieh, H.-S, Dayringer, H.E, Leimgruber, N.K, Stegeman, R.A, Anderson, K.S, Sikorski, J.A, Padgette, S.R, Kishore, G.M.
Deposit date:1991-04-05
Release date:1993-07-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure and topological symmetry of the glyphosate target 5-enolpyruvylshikimate-3-phosphate synthase: a distinctive protein fold.
Proc.Natl.Acad.Sci.USA, 88, 1991
1EO3
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BU of 1eo3 by Molmil
INHIBITION OF ECORV ENDONUCLEASE BY DEOXYRIBO-3'-S-PHOSPHOROTHIOLATES: A HIGH RESOLUTION X-RAY CRYSTALLOGRAPHIC STUDY
Descriptor: ACETIC ACID, DNA (5'-D(*CP*AP*AP*GP*AP*(TSP)P*AP*TP*CP*TP*T)-3'), MAGNESIUM ION, ...
Authors:Horton, N.C, Connolly, B.A, Perona, J.J.
Deposit date:2000-03-21
Release date:2000-04-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Inhibition of EcoRV Endonuclease by Deoxyribo-3'-S-phosphorothiolates: A High-Resolution X-ray Crystallographic Study
J.Am.Chem.Soc., 122, 2000
3V8W
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BU of 3v8w by Molmil
Crystal Structure of Interleukin-2 Inducible T-cell Kinase Itk Catalytic Domain with Thienopyrazolylindole Inhibitor 469
Descriptor: 3-[2-(5-phenyl-2H-thieno[3,2-c]pyrazol-3-yl)-1H-indol-6-yl]pentan-3-ol, SULFATE ION, Tyrosine-protein kinase ITK/TSK
Authors:McLean, L.R, Zhang, Y.
Deposit date:2011-12-23
Release date:2012-05-02
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:X-ray crystallographic structure-based design of selective thienopyrazole inhibitors for interleukin-2-inducible tyrosine kinase.
Bioorg.Med.Chem.Lett., 22, 2012
1EMC
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BU of 1emc by Molmil
GREEN FLUORESCENT PROTEIN FROM AEQUOREA VICTORIA, MUTANT
Descriptor: GREEN FLUORESCENT PROTEIN
Authors:Palm, G, Zdanov, A, Wlodawer, A.
Deposit date:1997-03-31
Release date:1997-08-20
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The structural basis for spectral variations in green fluorescent protein.
Nat.Struct.Biol., 4, 1997
3EP4
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BU of 3ep4 by Molmil
Human AdoMetDC E256Q mutant with no putrescine bound
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PYRUVIC ACID, S-adenosylmethionine decarboxylase alpha chain, ...
Authors:Bale, S, Lopez, M.M, Makhatadze, G.I, Fang, Q, Pegg, A.E, Ealick, S.E.
Deposit date:2008-09-29
Release date:2008-12-23
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase.
Biochemistry, 47, 2008
1EWT
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BU of 1ewt by Molmil
CRYSTAL STRUCTURE OF METABOTROPIC GLUTAMATE RECEPTOR SUBTYPE 1 LIGAND FREE FORM I
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, METABOTROPIC GLUTAMATE RECEPTOR SUBTYPE 1, SULFATE ION
Authors:Kunishima, N, Shimada, Y, Tsuji, Y, Jingami, H, Morikawa, K.
Deposit date:2000-04-27
Release date:2000-12-18
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Structural basis of glutamate recognition by a dimeric metabotropic glutamate receptor.
Nature, 407, 2000
3RGE
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BU of 3rge by Molmil
Crystal structure of the W5H mutant of human carbonic anhydrase II
Descriptor: Carbonic anhydrase 2, ZINC ION
Authors:Domsic, J.F, Robbins, A.H, McKenna, R.
Deposit date:2011-04-08
Release date:2012-02-22
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.096 Å)
Cite:Structure and catalysis by carbonic anhydrase II: role of active-site tryptophan 5.
Arch.Biochem.Biophys., 516, 2011
1EDK
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BU of 1edk by Molmil
STAPHYLOCOCCAL PROTEIN A E-DOMAIN (-60), NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor: STAPHYLOCOCCAL PROTEIN A
Authors:Starovasnik, M.A, Skelton, N.J, Fairbrother, W.J.
Deposit date:1996-07-22
Release date:1997-04-01
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of the E-domain of staphylococcal protein A.
Biochemistry, 35, 1996
1EXA
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BU of 1exa by Molmil
ENANTIOMER DISCRIMINATION ILLUSTRATED BY CRYSTAL STRUCTURES OF THE HUMAN RETINOIC ACID RECEPTOR HRARGAMMA LIGAND BINDING DOMAIN: THE COMPLEX WITH THE ACTIVE R-ENANTIOMER BMS270394.
Descriptor: DODECYL-ALPHA-D-MALTOSIDE, R-3-FLUORO-4-[2-HYDROXY-2-(5,5,8,8-TETRAMETHYL-5,6,7,8,-TETRAHYDRO-NAPHTALEN-2-YL)-ACETYLAMINO]-BENZOIC ACID, RETINOIC ACID RECEPTOR GAMMA-2
Authors:Klaholz, B.P, Mitschler, A, Belema, M, Zusi, C, Moras, D, Structural Proteomics in Europe (SPINE)
Deposit date:2000-05-02
Release date:2000-06-09
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Enantiomer discrimination illustrated by high-resolution crystal structures of the human nuclear receptor hRARgamma.
Proc.Natl.Acad.Sci.USA, 97, 2000
1EGR
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BU of 1egr by Molmil
SEQUENCE-SPECIFIC 1H N.M.R. ASSIGNMENTS AND DETERMINATION OF THE THREE-DIMENSIONAL STRUCTURE OF REDUCED ESCHERICHIA COLI GLUTAREDOXIN
Descriptor: GLUTAREDOXIN
Authors:Sodano, P, Xia, T.-H, Bushweller, J.H, Bjornberg, O, Holmgren, A, Billeter, M, Wuthrich, K.
Deposit date:1991-10-08
Release date:1993-10-31
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Sequence-specific 1H n.m.r. assignments and determination of the three-dimensional structure of reduced Escherichia coli glutaredoxin.
J.Mol.Biol., 221, 1991
1EXP
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BU of 1exp by Molmil
BETA-1,4-GLYCANASE CEX-CD
Descriptor: BETA-1,4-D-GLYCANASE CEX-CD, beta-D-glucopyranose-(1-4)-2-deoxy-2-fluoro-alpha-D-glucopyranose
Authors:White, A, Tull, D, Johns, K.L, Withers, S.G, Rose, D.R.
Deposit date:1996-01-11
Release date:1997-01-27
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystallographic observation of a covalent catalytic intermediate in a beta-glycosidase.
Nat.Struct.Biol., 3, 1996
3VAF
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BU of 3vaf by Molmil
Structure of U2AF65 variant with BrU3 DNA
Descriptor: 1,4-DIETHYLENE DIOXIDE, DNA 5'-D(*UP*UP*(BRU)P*(BRU)P*UP*UP*U)-3', GLYCEROL, ...
Authors:Jenkins, J.L, Kielkopf, C.L.
Deposit date:2011-12-29
Release date:2013-02-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs.
Nucleic Acids Res., 41, 2013
1EY0
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BU of 1ey0 by Molmil
STRUCTURE OF WILD-TYPE S. NUCLEASE AT 1.6 A RESOLUTION
Descriptor: STAPHYLOCOCCAL NUCLEASE
Authors:Chen, J, Lu, Z, Sakon, J, Stites, W.E.
Deposit date:2000-05-05
Release date:2000-10-18
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Increasing the thermostability of staphylococcal nuclease: implications for the origin of protein thermostability.
J.Mol.Biol., 303, 2000
1EV1
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BU of 1ev1 by Molmil
ECHOVIRUS 1
Descriptor: ECHOVIRUS 1, MYRISTIC ACID, PALMITIC ACID
Authors:Wien, M.W, Filman, D.J, Hogle, J.M.
Deposit date:1997-12-02
Release date:1999-01-27
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (3.55 Å)
Cite:Structure determination of echovirus 1.
Acta Crystallogr.,Sect.D, 54, 1998
3VAM
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BU of 3vam by Molmil
Structure of U2AF65 variant with BrU5C2 DNA
Descriptor: 1,4-DIETHYLENE DIOXIDE, DNA (5'-D(*UP*CP*UP*UP*(BRU)P*UP*U)-3'), GLYCEROL, ...
Authors:Jenkins, J.L, Kielkopf, C.L.
Deposit date:2011-12-29
Release date:2013-02-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs.
Nucleic Acids Res., 41, 2013
1EY8
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BU of 1ey8 by Molmil
STRUCTURE OF S. NUCLEASE STABILIZING TRIPLE MUTANT P117G/H124L/S128A
Descriptor: STAPHYLOCOCCAL NUCLEASE
Authors:Chen, J, Lu, Z, Sakon, J, Stites, W.E.
Deposit date:2000-05-05
Release date:2000-10-18
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Increasing the thermostability of staphylococcal nuclease: implications for the origin of protein thermostability.
J.Mol.Biol., 303, 2000
1EYF
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BU of 1eyf by Molmil
REFINED STRUCTURE OF THE DNA METHYL PHOSPHOTRIESTER REPAIR DOMAIN OF E. COLI ADA
Descriptor: ADA REGULATORY PROTEIN, ZINC ION
Authors:Lin, Y, Dotsch, V, Wintner, T, Peariso, K, Myers, L.C, Penner-Hahn, J.E, Verdine, G.L, Wagner, G.
Deposit date:2000-05-06
Release date:2003-09-09
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structural basis for the functional switch of the E. coli Ada protein
Biochemistry, 40, 2001
1EAK
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BU of 1eak by Molmil
Catalytic domain of proMMP-2 E404Q mutant
Descriptor: 72 KDA TYPE IV COLLAGENASE, CALCIUM ION, INHIBITOR PEPTIDE, ...
Authors:Bergmann, U, Tuuttila, A, Tryggvason, K, Morgunova, E.
Deposit date:2001-07-12
Release date:2002-08-22
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:Crystal Structure of Human Mmp-2 Reveals a New P
To be Published
1E8F
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BU of 1e8f by Molmil
STRUCTURE OF THE H61T MUTANT OF THE FLAVOENZYME VANILLYL-ALCOHOL OXIDASE IN THE APO FORM
Descriptor: VANILLYL-ALCOHOL OXIDASE
Authors:Mattevi, A, Fraaije, M.W.
Deposit date:2000-09-20
Release date:2000-09-21
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural Analysis of Flavinylation in Vanillyl-Alcohol Oxidase
J.Biol.Chem., 275, 2001
3R2B
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BU of 3r2b by Molmil
MK2 kinase bound to Compound 5b
Descriptor: 2'-[2-(1,3-benzodioxol-5-yl)pyrimidin-4-yl]-5',6'-dihydrospiro[piperidine-4,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one, MAP kinase-activated protein kinase 2
Authors:Oubrie, A, van Zeeland, M, Versteegh, J.
Deposit date:2011-03-14
Release date:2011-05-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure-based lead identification of ATP-competitive MK2 inhibitors.
Bioorg.Med.Chem.Lett., 21, 2011
3E5W
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BU of 3e5w by Molmil
Crystal Structure Analysis of FP611
Descriptor: Red fluorescent protein eqFP611
Authors:Nienhaus, K, Nar, H, Heilker, R, Wiedenmann, J, Nienhaus, G.U.
Deposit date:2008-08-14
Release date:2008-09-23
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Trans-cis isomerization is responsible for the red-shifted fluorescence in variants of the red fluorescent protein eqFP611.
J.Am.Chem.Soc., 130, 2008

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