4DK1
 
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6WPW
 | | GCGR-Gs signaling complex bound to a designed glucagon derivative | | Descriptor: | Glucagon derivative ZP3780, Glucagon receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Hilger, D, Krishna Kumar, K, Hu, H, Mathiesen, J.M, Skiniotis, G, Kobilka, B.K. | | Deposit date: | 2020-04-28 | | Release date: | 2020-08-12 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural insights into differences in G protein activation by family A and family B GPCRs.
Science, 369, 2020
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9E78
 | | 48-nm repeat of the Leishmania tarentolae doublet microtubule | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, ArcMAP1, ArcMAP2, ... | | Authors: | Doran, M.H, Ren, P, Hoog, J.L, Brown, A. | | Deposit date: | 2024-11-01 | | Release date: | 2025-03-12 | | Last modified: | 2025-03-26 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Evolutionary adaptations of doublet microtubules in trypanosomatid parasites.
Science, 387, 2025
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9D7R
 | | Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with Fva1 antimicrobial peptide, mRNA, A-site release factor 1, and deacylated P-site and E-site tRNAphe at 2.70A resolution | | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | | Authors: | Aleksandrova, E.V, Huang, W, Baliga, C, Atkinson, G.C, Vazquez-Laslop, N, Mankin, A.S, Polikanov, Y.S. | | Deposit date: | 2024-08-17 | | Release date: | 2024-11-13 | | Last modified: | 2025-03-19 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Activity, structure, and diversity of Type II proline-rich antimicrobial peptides from insects.
Embo Rep., 25, 2024
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6YFU
 | | Virus-like particle of Wenzhou levi-like virus 4 | | Descriptor: | coat protein | | Authors: | Rumnieks, J, Kalnins, G, Sisovs, M, Lieknina, I, Tars, K. | | Deposit date: | 2020-03-26 | | Release date: | 2020-09-02 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (4.018 Å) | | Cite: | Three-dimensional structure of 22 uncultured ssRNA bacteriophages: Flexibility of the coat protein fold and variations in particle shapes.
Sci Adv, 6, 2020
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9D7S
 | | Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with Api antimicrobial peptide, mRNA, A-site release factor 1, and deacylated P-site and E-site tRNAphe at 2.85A resolution | | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | | Authors: | Aleksandrova, E.V, Huang, W, Baliga, C, Atkinson, G.C, Vazquez-Laslop, N, Mankin, A.S, Polikanov, Y.S. | | Deposit date: | 2024-08-17 | | Release date: | 2024-11-13 | | Last modified: | 2025-03-19 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Activity, structure, and diversity of Type II proline-rich antimicrobial peptides from insects.
Embo Rep., 25, 2024
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9IHS
 | | Microbial transglutaminase mutant - D3C/G283C | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Suzuki, M, Date, M, Kashiwagi, T, Takahashi, K, Nakamura, A, Tanokura, M, Suzuki, E, Yokoyama, K. | | Deposit date: | 2024-06-18 | | Release date: | 2024-09-18 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Random mutagenesis and disulfide bond formation improved thermostability in microbial transglutaminase.
Appl.Microbiol.Biotechnol., 108, 2024
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4DVY
 | | Crystal structure of the Helicobacter pylori CagA oncoprotein | | Descriptor: | Cytotoxicity-associated immunodominant antigen | | Authors: | Hayashi, T, Senda, M, Morohashi, H, Higashi, H, Horio, M, Kashiba, Y, Nagase, L, Sasaya, D, Shimizu, T, Venugopalan, N, Kumeta, H, Noda, N, Inagaki, F, Senda, T, Hatakeyama, M. | | Deposit date: | 2012-02-23 | | Release date: | 2012-07-25 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Tertiary Structure-Function Analysis Reveals the Pathogenic Signaling Potentiation Mechanism of Helicobacter pylori Oncogenic Effector CagA
Cell Host Microbe, 12, 2012
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6YFB
 | | Virus-like particle of bacteriophage AVE016 | | Descriptor: | coat protein | | Authors: | Rumnieks, J, Kalnins, G, Sisovs, M, Lieknina, I, Tars, K. | | Deposit date: | 2020-03-26 | | Release date: | 2020-09-02 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (3.59 Å) | | Cite: | Three-dimensional structure of 22 uncultured ssRNA bacteriophages: Flexibility of the coat protein fold and variations in particle shapes.
Sci Adv, 6, 2020
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6YFE
 | | Virus-like particle of Beihai levi-like virus 19 | | Descriptor: | CALCIUM ION, coat protein | | Authors: | Rumnieks, J, Kalnins, G, Sisovs, M, Lieknina, I, Tars, K. | | Deposit date: | 2020-03-26 | | Release date: | 2020-09-02 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (3.794 Å) | | Cite: | Three-dimensional structure of 22 uncultured ssRNA bacteriophages: Flexibility of the coat protein fold and variations in particle shapes.
Sci Adv, 6, 2020
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6YFO
 | | Virus-like particle of bacteriophage GQ-907 | | Descriptor: | coat protein | | Authors: | Rumnieks, J, Kalnins, G, Sisovs, M, Lieknina, I, Tars, K. | | Deposit date: | 2020-03-26 | | Release date: | 2020-09-02 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (3.484 Å) | | Cite: | Three-dimensional structure of 22 uncultured ssRNA bacteriophages: Flexibility of the coat protein fold and variations in particle shapes.
Sci Adv, 6, 2020
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6YFJ
 | | Virus-like particle of bacteriophage ESE001 | | Descriptor: | coat protein | | Authors: | Rumnieks, J, Kalnins, G, Sisovs, M, Lieknina, I, Tars, K. | | Deposit date: | 2020-03-26 | | Release date: | 2020-09-02 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (3.233 Å) | | Cite: | Three-dimensional structure of 22 uncultured ssRNA bacteriophages: Flexibility of the coat protein fold and variations in particle shapes.
Sci Adv, 6, 2020
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6YFP
 | | Virus-like particle of bacteriophage GQ-112 | | Descriptor: | coat protein | | Authors: | Rumnieks, J, Kalnins, G, Sisovs, M, Lieknina, I, Tars, K. | | Deposit date: | 2020-03-26 | | Release date: | 2020-09-02 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Three-dimensional structure of 22 uncultured ssRNA bacteriophages: Flexibility of the coat protein fold and variations in particle shapes.
Sci Adv, 6, 2020
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9DFC
 | | Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with lasso peptide lariocidin, mRNA, aminoacylated A-site Phe-tRNAphe, aminoacylated P-site fMet-tRNAmet, and deacylated E-site tRNAphe at 2.50A resolution | | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | | Authors: | Aleksandrova, E.V, Travin, D.Y, Jangra, M, Kaur, M, Darwish, L, Koteva, K, Klepacki, D, Wang, W, Tiffany, M, Sokaribo, A, Coombes, B.K, Vazquez-Laslop, N, Wright, G.D, Mankin, A.S, Polikanov, Y.S. | | Deposit date: | 2024-08-29 | | Release date: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | A Broad Spectrum Lasso Peptide Antibiotic Targeting the Bacterial Ribosome.
Res Sq, 2024
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4GJI
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9DFE
 | | Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with lasso peptide lariocidin and protein Y at 2.60A resolution | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ... | | Authors: | Aleksandrova, E.V, Travin, D.Y, Jangra, M, Kaur, M, Darwish, L, Koteva, K, Klepacki, D, Wang, W, Tiffany, M, Sokaribo, A, Coombes, B.K, Vazquez-Laslop, N, Wright, G.D, Mankin, A.S, Polikanov, Y.S. | | Deposit date: | 2024-08-29 | | Release date: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | A Broad Spectrum Lasso Peptide Antibiotic Targeting the Bacterial Ribosome.
Res Sq, 2024
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6YF7
 | | Virus-like particle of bacteriophage AC | | Descriptor: | Coat protein | | Authors: | Rumnieks, J, Kalnins, G, Sisovs, M, Lieknina, I, Tars, K. | | Deposit date: | 2020-03-26 | | Release date: | 2020-09-02 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Three-dimensional structure of 22 uncultured ssRNA bacteriophages: Flexibility of the coat protein fold and variations in particle shapes.
Sci Adv, 6, 2020
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9GR1
 | | E. coli 70S-TEC complex in delivery state | | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S16, ... | | Authors: | Webster, M.W, Weixlbaumer, A. | | Deposit date: | 2024-09-10 | | Release date: | 2024-11-20 | | Last modified: | 2025-03-12 | | Method: | ELECTRON MICROSCOPY (3.17 Å) | | Cite: | Molecular basis of mRNA delivery to the bacterial ribosome.
Science, 386, 2024
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9D7T
 | | Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with Api137 antimicrobial peptide, mRNA, A-site release factor 1, and deacylated P-site and E-site tRNAphe at 2.70A resolution | | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | | Authors: | Aleksandrova, E.V, Huang, W, Baliga, C, Atkinson, G.C, Vazquez-Laslop, N, Mankin, A.S, Polikanov, Y.S. | | Deposit date: | 2024-08-17 | | Release date: | 2024-11-13 | | Last modified: | 2025-03-19 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Activity, structure, and diversity of Type II proline-rich antimicrobial peptides from insects.
Embo Rep., 25, 2024
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9HAR
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9C3H
 | | Structure of the CNOT3-bound human 80S ribosome with tRNA-ARG in the P-site. | | Descriptor: | 18S rRNA, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 28S rRNA, ... | | Authors: | Erzberger, J.P, Cruz, V.E. | | Deposit date: | 2024-06-01 | | Release date: | 2024-12-04 | | Method: | ELECTRON MICROSCOPY (2 Å) | | Cite: | Specific tRNAs promote mRNA decay by recruiting the CCR4-NOT complex to translating ribosomes.
Science, 386, 2024
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4FMA
 | | EspG structure | | Descriptor: | ACETIC ACID, EspG protein, FORMIC ACID, ... | | Authors: | Shao, F, Zhu, Y, Hu, L. | | Deposit date: | 2012-06-16 | | Release date: | 2012-09-05 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Structurally Distinct Bacterial TBC-like GAPs Link Arf GTPase to Rab1 Inactivation to Counteract Host Defenses.
Cell(Cambridge,Mass.), 150, 2012
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6YFS
 | | Virus-like particle of bacteriophage PQ-465 | | Descriptor: | coat protein | | Authors: | Rumnieks, J, Kalnins, G, Sisovs, M, Lieknina, I, Tars, K. | | Deposit date: | 2020-03-26 | | Release date: | 2020-09-02 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (3.498 Å) | | Cite: | Three-dimensional structure of 22 uncultured ssRNA bacteriophages: Flexibility of the coat protein fold and variations in particle shapes.
Sci Adv, 6, 2020
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9CPC
 | | Atomic model of porcine brain ventricles cilia doublet microtubule (48-nm periodicity) | | Descriptor: | Armadillo repeat-containing protein 4 isoform 1, CFAP107/C1orf158, Chromosome 1 C15orf65 homolog, ... | | Authors: | Sun, C, Zeng, J, Zhang, R. | | Deposit date: | 2024-07-18 | | Release date: | 2024-10-23 | | Last modified: | 2025-03-19 | | Method: | ELECTRON MICROSCOPY (3.65 Å) | | Cite: | Structural diversity of axonemes across mammalian motile cilia.
Nature, 637, 2025
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6YFD
 | | Virus-like particle of Beihai levi-like virus 14 | | Descriptor: | coat protein | | Authors: | Rumnieks, J, Kalnins, G, Sisovs, M, Lieknina, I, Tars, K. | | Deposit date: | 2020-03-26 | | Release date: | 2020-09-02 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Three-dimensional structure of 22 uncultured ssRNA bacteriophages: Flexibility of the coat protein fold and variations in particle shapes.
Sci Adv, 6, 2020
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