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6KZA
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Crystal structure of the complex of the interaction domains of E. coli DnaB helicase and DnaC helicase loader
Descriptor: DNA replication protein DnaC, Replicative DNA helicase
Authors:Nagata, K, Okada, A, Ohtsuka, J, Ohkuri, T, Akama, Y, Sakiyama, Y, Miyazaki, E, Horita, S, Katayama, T, Ueda, T, Tanokura, M.
Deposit date:2019-09-23
Release date:2019-11-20
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structure of the complex of the interaction domains of Escherichia coli DnaB helicase and DnaC helicase loader: structural basis implying a distortion-accumulation mechanism for the DnaB ring opening caused by DnaC binding.
J.Biochem., 167, 2020
9FJP
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BU of 9fjp by Molmil
Cryo-EM structure of Mycobacterium tuberculosis sigma-B RNA polymerase bound to -10 promoter element ssDNA oligo
Descriptor: DNA (17-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Brodolin, K, Marechal, N.
Deposit date:2024-05-31
Release date:2025-04-02
Last modified:2025-04-30
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Single-stranded DNA drives sigma subunit loading onto mycobacterial RNA polymerase to unlock initiation-competent conformations.
Nucleic Acids Res., 53, 2025
9FJS
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BU of 9fjs by Molmil
Cryo-EM structure of Mycobacterium tuberculosis sigma-B RNA polymerase bound to -10 promoter element ssDNA oligo - sigma-B undocked conformation
Descriptor: DNA (17-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Brodolin, K, Blaise, M.
Deposit date:2024-05-31
Release date:2025-04-02
Last modified:2025-05-07
Method:ELECTRON MICROSCOPY (3.48 Å)
Cite:Single-stranded DNA drives sigma subunit loading onto mycobacterial RNA polymerase to unlock initiation-competent conformations.
Nucleic Acids Res., 53, 2025
5FZ5
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BU of 5fz5 by Molmil
Transcription initiation complex structures elucidate DNA opening (CC)
Descriptor: DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ...
Authors:Plaschka, C, Hantsche, M, Dienemann, C, Burzinski, C, Plitzko, J, Cramer, P.
Deposit date:2016-03-10
Release date:2016-05-18
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (8.8 Å)
Cite:Transcription Initiation Complex Structures Elucidate DNA Opening
Nature, 533, 2016
5X6M
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Crystal Structure of SMAD5-MH1 in complex with a composite DNA sequence
Descriptor: DNA (5'-D(P*AP*TP*CP*AP*GP*AP*CP*TP*GP*CP*CP*GP*GP*CP*AP*GP*TP*CP*TP*AP*TP*A)-3'), DNA (5'-D(P*TP*TP*AP*TP*AP*GP*AP*CP*TP*GP*CP*CP*GP*GP*CP*AP*GP*TP*CP*TP*GP*A)-3'), Mothers against decapentaplegic homolog 5, ...
Authors:Chai, N, Wang, J, Wang, Z.X, Wu, J.W.
Deposit date:2017-02-22
Release date:2017-03-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for the Smad5 MH1 domain to recognize different DNA sequences.
Nucleic Acids Res., 43, 2015
5X6H
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Crystal Structure of SMAD5-MH1/GC-BRE DNA complex
Descriptor: DNA (5'-D(P*GP*TP*AP*TP*GP*GP*CP*GP*CP*CP*AP*TP*AP*C)-3'), Mothers against decapentaplegic homolog 5, ZINC ION
Authors:Chai, N, Wang, J, Wang, Z.X, Wu, J.W.
Deposit date:2017-02-22
Release date:2017-03-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for the Smad5 MH1 domain to recognize different DNA sequences.
Nucleic Acids Res., 43, 2015
6FB9
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BU of 6fb9 by Molmil
Crystal Structure of the I-CreI Homing Endonuclease D75N variant in complex with an altered version of its target DNA at 5NNN region in the presence of Manganese
Descriptor: DNA (5'-D(*TP*CP*AP*AP*AP*AP*CP*GP*TP*CP*GP*TP*AP*C)-3'), DNA (5'-D(*TP*CP*AP*AP*AP*AP*CP*TP*GP*CP*GP*TP*AP*C)-3'), DNA (5'-D(P*GP*AP*CP*GP*TP*TP*TP*TP*GP*A)-3'), ...
Authors:Molina, R, Prieto, J.
Deposit date:2017-12-18
Release date:2018-07-18
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Understanding the indirect DNA read-out specificity of I-CreI Meganuclease.
Sci Rep, 8, 2018
6FB6
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Crystal Structure of a Tailored I-CreI Homing Endonuclease Protein (3115 variant) in complex with an altered version of its target DNA (Haemoglobin beta subunit gene) at 5NNN region in the presence of Manganese
Descriptor: DNA (5'-D(*TP*CP*AP*GP*AP*CP*TP*TP*GP*TP*CP*CP*AP*C)-3'), DNA (5'-D(*TP*CP*TP*GP*AP*CP*TP*CP*CP*TP*GP*TP*GP*G)-3'), DNA (5'-D(P*AP*CP*AP*AP*GP*TP*CP*TP*GP*A)-3'), ...
Authors:Molina, R, Prieto, J.
Deposit date:2017-12-18
Release date:2018-07-18
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Understanding the indirect DNA read-out specificity of I-CreI Meganuclease.
Sci Rep, 8, 2018
6F5B
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BU of 6f5b by Molmil
Structure of ARTD2/PARP2 WGR domain bound to double stranded DNA with 5'phosphate
Descriptor: DNA (5'-D(P*GP*CP*CP*TP*AP*TP*AP*GP*GP*C)-3'), Poly [ADP-ribose] polymerase 2
Authors:Obaji, E, Haikarainen, T, Lehtio, L.
Deposit date:2017-12-01
Release date:2018-10-10
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for DNA break recognition by ARTD2/PARP2.
Nucleic Acids Res., 46, 2018
6F5F
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BU of 6f5f by Molmil
Structure of ARTD2/PARP2 WGR domain bound to double strand DNA with 5 nucleotide overhang and 5'phosphate
Descriptor: DNA (5'-D(P*CP*GP*GP*TP*CP*GP*CP*CP*TP*AP*TP*AP*GP*GP*C)-3'), Poly [ADP-ribose] polymerase 2
Authors:Obaji, E, Haikarainen, T, Lehtio, L.
Deposit date:2017-12-01
Release date:2018-10-10
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:Structural basis for DNA break recognition by ARTD2/PARP2.
Nucleic Acids Res., 46, 2018
7C17
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BU of 7c17 by Molmil
The cryo-EM structure of E. coli CueR transcription activation complex with fully duplex promoter DNA
Descriptor: DNA (72-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Fang, C.L, Zhang, Y.
Deposit date:2020-05-02
Release date:2020-09-30
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.22 Å)
Cite:CueR activates transcription through a DNA distortion mechanism.
Nat.Chem.Biol., 17, 2021
8AV6
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BU of 8av6 by Molmil
CryoEM structure of INO80 core nucleosome complex in closed grappler conformation
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DASH complex subunit DAD4, ...
Authors:Kunert, F, Metzner, F.J, Eustermann, S, Jung, J, Woike, S, Schall, K, Kostrewa, D, Hopfner, K.P.
Deposit date:2022-08-26
Release date:2022-12-14
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (4.68 Å)
Cite:Structural mechanism of extranucleosomal DNA readout by the INO80 complex.
Sci Adv, 8, 2022
1TTD
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BU of 1ttd by Molmil
SOLUTION-STATE STRUCTURE OF A DNA DODECAMER DUPLEX CONTAINING A CIS-SYN THYMINE CYCLOBUTANE DIMER
Descriptor: DNA (5'-D(*CP*TP*TP*AP*AP*TP*TP*CP*GP*TP*GP*C)-3'), DNA (5'-D(*GP*CP*AP*CP*GP*AP*AP*(TTD)P*AP*AP*G)-3')
Authors:Mcateer, K, Jing, Y, Kao, J, Taylor, J.-S, Kennedy, M.A.
Deposit date:1999-01-20
Release date:1999-02-02
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution-state structure of a DNA dodecamer duplex containing a Cis-syn thymine cyclobutane dimer, the major UV photoproduct of DNA.
J.Mol.Biol., 282, 1998
8ATF
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BU of 8atf by Molmil
Nucleosome-bound Ino80 ATPase
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA (226-MER), DNA (227-MER), ...
Authors:Kunert, F, Metzner, F.J, Eustermann, S, Jung, J, Woike, S, Schall, K, Kostrewa, D, Hopfner, K.P.
Deposit date:2022-08-23
Release date:2022-12-14
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.45 Å)
Cite:Structural mechanism of extranucleosomal DNA readout by the INO80 complex.
Sci Adv, 8, 2022
5FYW
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BU of 5fyw by Molmil
Transcription initiation complex structures elucidate DNA opening (OC)
Descriptor: DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ...
Authors:Plaschka, C, Hantsche, M, Dienemann, C, Burzinski, C, Plitzko, J, Cramer, P.
Deposit date:2016-03-10
Release date:2016-05-18
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (4.35 Å)
Cite:Transcription Initiation Complex Structures Elucidate DNA Opening
Nature, 533, 2016
6ES2
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BU of 6es2 by Molmil
Structure of CDX2-DNA(CAA)
Descriptor: DNA (5'-D(P*GP*GP*AP*GP*GP*CP*AP*AP*TP*AP*AP*AP*AP*CP*AP*CP*AP*A)-3'), DNA (5'-D(P*TP*TP*GP*TP*GP*TP*TP*TP*TP*AP*TP*TP*GP*CP*CP*TP*CP*C)-3'), Homeobox protein CDX-2
Authors:Morgunova, E, Yin, Y, Jolma, A, Popov, A, Taipale, J.
Deposit date:2017-10-19
Release date:2018-03-21
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Two distinct DNA sequences recognized by transcription factors represent enthalpy and entropy optima.
Elife, 7, 2018
7GAT
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BU of 7gat by Molmil
SOLUTION NMR STRUCTURE OF THE L22V MUTANT DNA BINDING DOMAIN OF AREA COMPLEXED TO A 13 BP DNA CONTAINING A TGATA SITE, 34 STRUCTURES
Descriptor: DNA (5'-D(*CP*AP*GP*TP*GP*AP*TP*AP*GP*AP*GP*AP*C)-3'), DNA (5'-D(*GP*TP*CP*TP*CP*TP*AP*TP*CP*AP*CP*TP*G)-3'), NITROGEN REGULATORY PROTEIN AREA, ...
Authors:Clore, G.M, Starich, M, Wikstrom, M, Gronenborn, A.M.
Deposit date:1997-11-07
Release date:1998-01-28
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The solution structure of the Leu22-->Val mutant AREA DNA binding domain complexed with a TGATAG core element defines a role for hydrophobic packing in the determination of specificity.
J.Mol.Biol., 277, 1998
8JH3
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BU of 8jh3 by Molmil
RNA polymerase II elongation complex containing 40 bp upstream DNA loop, stalled at SHL(-1) of the nucleosome
Descriptor: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ...
Authors:Akatsu, M, Fujita, R, Ogasawara, M, Ehara, H, Kujirai, T, Takizawa, Y, Sekine, S, Kurumizaka, H.
Deposit date:2023-05-22
Release date:2023-11-29
Last modified:2023-12-20
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cryo-EM structures of RNA polymerase II-nucleosome complexes rewrapping transcribed DNA.
J.Biol.Chem., 299, 2023
8JH4
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BU of 8jh4 by Molmil
RNA polymerase II elongation complex containing 60 bp upstream DNA loop, stalled at SHL(-1) of the nucleosome
Descriptor: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ...
Authors:Akatsu, M, Fujita, R, Ogasawara, M, Ehara, H, Kujirai, T, Takizawa, Y, Sekine, S, Kurumizaka, H.
Deposit date:2023-05-22
Release date:2023-11-29
Last modified:2023-12-20
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structures of RNA polymerase II-nucleosome complexes rewrapping transcribed DNA.
J.Biol.Chem., 299, 2023
1BBX
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BU of 1bbx by Molmil
NON-SPECIFIC PROTEIN-DNA INTERACTIONS IN THE SSO7D-DNA COMPLEX, NMR, 1 STRUCTURE
Descriptor: DNA (5'-D(*CP*TP*AP*GP*CP*GP*CP*GP*CP*TP*AP*G)-3'), DNA-BINDING PROTEIN 7D
Authors:Agback, P, Baumann, H, Knapp, S, Ladenstein, R, Hard, T.
Deposit date:1998-04-24
Release date:1998-10-14
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Architecture of Nonspecific Protein-DNA Interactions in the Sso7D-DNA Complex
Nat.Struct.Biol., 5, 1998
5NSS
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BU of 5nss by Molmil
Cryo-EM structure of RNA polymerase-sigma54 holoenzyme with promoter DNA and transcription activator PspF intermedate complex
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta',DNA-directed RNA polymerase subunit beta',DNA-directed RNA polymerase subunit beta', ...
Authors:Glyde, R, Ye, F.Z, Darbari, V.C, Zhang, N, Buck, M, Zhang, X.D.
Deposit date:2017-04-26
Release date:2017-06-28
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Structures of RNA Polymerase Closed and Intermediate Complexes Reveal Mechanisms of DNA Opening and Transcription Initiation.
Mol. Cell, 67, 2017
1B3T
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BU of 1b3t by Molmil
EBNA-1 NUCLEAR PROTEIN/DNA COMPLEX
Descriptor: DNA (5'-D(*GP*GP*GP*AP*AP*GP*CP*AP*TP*AP*TP*GP*CP*TP*TP*CP*CP*C)-3'), PROTEIN (NUCLEAR PROTEIN EBNA1)
Authors:Bochkarev, A, Bochkareva, E, Edwards, A, Frappier, L.
Deposit date:1998-12-14
Release date:1998-12-15
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The 2.2 A structure of a permanganate-sensitive DNA site bound by the Epstein-Barr virus origin binding protein, EBNA1.
J.Mol.Biol., 284, 1998
1A1F
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BU of 1a1f by Molmil
DSNR (ZIF268 VARIANT) ZINC FINGER-DNA COMPLEX (GACC SITE)
Descriptor: DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*AP*CP*C)-3'), DNA (5'-D(*TP*GP*GP*TP*CP*CP*CP*AP*CP*GP*C)-3'), THREE-FINGER ZIF268 PEPTIDE, ...
Authors:Elrod-Erickson, M, Benson, T.E, Pabo, C.O.
Deposit date:1997-12-10
Release date:1998-06-10
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:High-resolution structures of variant Zif268-DNA complexes: implications for understanding zinc finger-DNA recognition.
Structure, 6, 1998
1A1J
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BU of 1a1j by Molmil
RADR (ZIF268 VARIANT) ZINC FINGER-DNA COMPLEX (GCGT SITE)
Descriptor: DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*CP*GP*T)-3'), DNA (5'-D(*TP*AP*CP*GP*CP*CP*CP*AP*CP*GP*C)-3'), PROTEIN (RADR ZIF268 ZINC FINGER PEPTIDE), ...
Authors:Elrod-Erickson, M, Benson, T.E, Pabo, C.O.
Deposit date:1997-12-10
Release date:1998-06-17
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:High-resolution structures of variant Zif268-DNA complexes: implications for understanding zinc finger-DNA recognition.
Structure, 6, 1998
1A1H
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BU of 1a1h by Molmil
QGSR (ZIF268 VARIANT) ZINC FINGER-DNA COMPLEX (GCAC SITE)
Descriptor: DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*CP*AP*C)-3'), DNA (5'-D(*TP*GP*TP*GP*CP*CP*CP*AP*CP*GP*C)-3'), QGSR ZINC FINGER PEPTIDE, ...
Authors:Elrod-Erickson, M, Benson, T.E, Pabo, C.O.
Deposit date:1997-12-10
Release date:1998-06-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:High-resolution structures of variant Zif268-DNA complexes: implications for understanding zinc finger-DNA recognition.
Structure, 6, 1998

238582

数据于2025-07-09公开中

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