1TS4
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![BU of 1ts4 by Molmil](/molmil-images/mine/1ts4) | Q139K MUTANT OF TOXIC SHOCK SYNDROME TOXIN-1 FROM S. AUREUS | Descriptor: | TOXIC SHOCK SYNDROME TOXIN-1 | Authors: | Earhart, C.A, Mitchell, D.T, Murray, D.L, Pinheiro, D.M, Matsumura, M, Schlievert, P.M, Ohlendorf, D.H. | Deposit date: | 1997-10-10 | Release date: | 1998-12-16 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structures of five mutants of toxic shock syndrome toxin-1 with reduced biological activity. Biochemistry, 37, 1998
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1TS3
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![BU of 1ts3 by Molmil](/molmil-images/mine/1ts3) | H135A MUTANT OF TOXIC SHOCK SYNDROME TOXIN-1 FROM S. AUREUS | Descriptor: | TOXIC SHOCK SYNDROME TOXIN-1 | Authors: | Earhart, C.A, Mitchell, D.T, Murray, D.L, Pinheiro, D.M, Matsumura, M, Schlievert, P.M, Ohlendorf, D.H. | Deposit date: | 1997-10-10 | Release date: | 1998-12-16 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of five mutants of toxic shock syndrome toxin-1 with reduced biological activity. Biochemistry, 37, 1998
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1TS2
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![BU of 1ts2 by Molmil](/molmil-images/mine/1ts2) | T128A MUTANT OF TOXIC SHOCK SYNDROME TOXIN-1 FROM S. AUREUS | Descriptor: | TOXIC SHOCK SYNDROME TOXIN-1 | Authors: | Earhart, C.A, Mitchell, D.T, Murray, D.L, Pinheiro, D.M, Matsumura, M, Schlievert, P.M, Ohlendorf, D.H. | Deposit date: | 1997-10-09 | Release date: | 1998-12-16 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structures of five mutants of toxic shock syndrome toxin-1 with reduced biological activity. Biochemistry, 37, 1998
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1T5X
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![BU of 1t5x by Molmil](/molmil-images/mine/1t5x) | HLA-DR1 in complex with a synthetic peptide (AAYSDQATPLLLSPR) and the superantigen SEC3-3B2 | Descriptor: | 15-mer peptide fragment of Regulatory protein MIG1, Enterotoxin type C-3, HLA class II histocompatibility antigen, ... | Authors: | Zavala-Ruiz, Z, Strug, I, Anderson, M.W, Gorski, J, Stern, L.J. | Deposit date: | 2004-05-05 | Release date: | 2004-08-17 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | A Polymorphic Pocket at the P10 Position Contributes to Peptide Binding Specificity in Class II MHC Proteins Chem.Biol., 11, 2004
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1SXT
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![BU of 1sxt by Molmil](/molmil-images/mine/1sxt) | STAPHYLOCOCCAL ENTEROTOXIN TYPE A (SEA) CO-CRYSTALLISED WITH ZINC | Descriptor: | STAPHYLOCOCCAL ENTEROTOXIN TYPE A, ZINC ION | Authors: | Sundstrom, S.M. | Deposit date: | 1996-11-14 | Release date: | 1997-11-19 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The Co-crystal structure of staphylococcal enterotoxin type A with Zn2+ at 2.7 A resolution. Implications for major histocompatibility complex class II binding. J.Biol.Chem., 271, 1996
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1STE
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![BU of 1ste by Molmil](/molmil-images/mine/1ste) | |
1SJH
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![BU of 1sjh by Molmil](/molmil-images/mine/1sjh) | HLA-DR1 complexed with a 13 residue HIV capsid peptide | Descriptor: | Enterotoxin type C-3, GAG polyprotein, HLA class II histocompatibility antigen, ... | Authors: | Zavala-Ruiz, Z, Strug, I, Walker, B.D, Norris, P.J, Stern, L.J. | Deposit date: | 2004-03-03 | Release date: | 2004-08-17 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | A hairpin turn in a class II MHC-bound peptide orients residues outside the binding groove for T cell recognition. Proc.Natl.Acad.Sci.Usa, 101, 2004
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1SJE
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![BU of 1sje by Molmil](/molmil-images/mine/1sje) | HLA-DR1 complexed with a 16 residue HIV capsid peptide bound in a hairpin conformation | Descriptor: | Enterotoxin type C-3, GAG polyprotein, HLA class II histocompatibility antigen, ... | Authors: | Zavala-Ruiz, Z, Strug, I, Walker, B.D, Norris, P.J, Stern, L.J. | Deposit date: | 2004-03-03 | Release date: | 2004-08-17 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | A hairpin turn in a class II MHC-bound peptide orients residues outside the binding groove for T cell recognition. Proc.Natl.Acad.Sci.Usa, 101, 2004
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1SEB
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![BU of 1seb by Molmil](/molmil-images/mine/1seb) | COMPLEX OF THE HUMAN MHC CLASS II GLYCOPROTEIN HLA-DR1 AND THE BACTERIAL SUPERANTIGEN SEB | Descriptor: | ENDOGENOUS PEPTIDE MODEL, POLY-ALA, ENTEROTOXIN TYPE B, ... | Authors: | Jardetzky, T.S, Brown, J.H, Gorga, J.C, Stern, L.J, Urban, R.G, Chi, Y.I, Stauffacher, C, Strominger, J.L, Wiley, D.C. | Deposit date: | 1995-11-26 | Release date: | 1996-06-20 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Three-dimensional structure of a human class II histocompatibility molecule complexed with superantigen. Nature, 368, 1994
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1SE4
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![BU of 1se4 by Molmil](/molmil-images/mine/1se4) | STAPHYLOCOCCAL ENTEROTOXIN B COMPLEXED WITH LACTOSE | Descriptor: | STAPHYLOCOCCAL ENTEROTOXIN B, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | Authors: | Swaminathan, S, Sax, M. | Deposit date: | 1997-04-16 | Release date: | 1997-10-15 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Residues defining V beta specificity in staphylococcal enterotoxins. Nat.Struct.Biol., 2, 1995
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1SE3
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![BU of 1se3 by Molmil](/molmil-images/mine/1se3) | STAPHYLOCOCCAL ENTEROTOXIN B COMPLEXED WITH GM3 TRISACCHARIDE | Descriptor: | N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, STAPHYLOCOCCAL ENTEROTOXIN B | Authors: | Swaminathan, S, Sax, M. | Deposit date: | 1996-10-11 | Release date: | 1997-06-16 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Residues defining V beta specificity in staphylococcal enterotoxins. Nat.Struct.Biol., 2, 1995
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1SE2
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![BU of 1se2 by Molmil](/molmil-images/mine/1se2) | |
1SBB
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![BU of 1sbb by Molmil](/molmil-images/mine/1sbb) | T-CELL RECEPTOR BETA CHAIN COMPLEXED WITH SUPERANTIGEN SEB | Descriptor: | PROTEIN (14.3.D T CELL ANTIGEN RECEPTOR), PROTEIN (STAPHYLOCOCCAL ENTEROTOXIN B) | Authors: | Li, H, Mariuzza, R.A. | Deposit date: | 1999-02-22 | Release date: | 1999-03-01 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Three-dimensional structure of the complex between a T cell receptor beta chain and the superantigen staphylococcal enterotoxin B. Immunity, 9, 1998
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1QIL
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![BU of 1qil by Molmil](/molmil-images/mine/1qil) | |
1PYW
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![BU of 1pyw by Molmil](/molmil-images/mine/1pyw) | Human class II MHC protein HLA-DR1 bound to a designed peptide related to influenza virus hemagglutinin, FVKQNA(MAA)AL, in complex with staphylococcal enterotoxin C3 variant 3B2 (SEC3-3B2) | Descriptor: | 9-residue influenza virus hemagglutinin related peptide FVKQNA(MAA)AL, Enterotoxin type C-3, HLA class II histocompatibility antigen, ... | Authors: | Zavala-Ruiz, Z, Sundberg, E.J, Stone, J.D, DeOliveira, D.B, Chan, I.C, Svendsen, J, Mariuzza, R.A, Stern, L.J. | Deposit date: | 2003-07-09 | Release date: | 2003-12-09 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Exploration of the P6/P7 region of the peptide-binding site of the human class II Major Histocompatability Complex Protein HLA-DR1 J.Biol.Chem., 278, 2003
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1M4V
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![BU of 1m4v by Molmil](/molmil-images/mine/1m4v) | Crystal structure of SET3, a superantigen-like protein from Staphylococcus aureus | Descriptor: | SET3, superantigen-like protein | Authors: | Arcus, V.L, Langley, R, Proft, T, Fraser, J.D, Baker, E.N. | Deposit date: | 2002-07-05 | Release date: | 2002-07-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The three-dimensional structure of a superantigen-like protein, SET3, from a pathogenicity island of the Staphylococcus aureus genome J.Biol.Chem., 277, 2002
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1LO5
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![BU of 1lo5 by Molmil](/molmil-images/mine/1lo5) | Crystal structure of the D227A variant of Staphylococcal enterotoxin A in complex with human MHC class II | Descriptor: | HLA class II histocompatibility antigen, DR alpha chain, DR-1 beta chain, ... | Authors: | Petersson, K, Thunnissen, M, Forsberg, G, Walse, B. | Deposit date: | 2002-05-06 | Release date: | 2002-12-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crystal Structure of a SEA Variant in Complex with MHC Class II Reveals the Ability of SEA to Crosslink MHC Molecules Structure, 10, 2002
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1L0Y
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![BU of 1l0y by Molmil](/molmil-images/mine/1l0y) | T cell receptor beta chain complexed with superantigen SpeA soaked with zinc | Descriptor: | 14.3.d T cell receptor beta chain, Exotoxin type A, GLYCEROL, ... | Authors: | Li, H, Sundberg, E.J, Mariuzza, R.A. | Deposit date: | 2002-02-14 | Release date: | 2002-04-03 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structures of two streptococcal superantigens bound to TCR beta chains reveal diversity in the architecture of T cell signaling complexes. Structure, 10, 2002
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1L0X
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![BU of 1l0x by Molmil](/molmil-images/mine/1l0x) | |
1KTK
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![BU of 1ktk by Molmil](/molmil-images/mine/1ktk) | Complex of Streptococcal pyrogenic enterotoxin C (SpeC) with a human T cell receptor beta chain (Vbeta2.1) | Descriptor: | Exotoxin type C, T-cell receptor beta chain | Authors: | Sundberg, E.J, Li, H, Llera, A.S, McCormick, J.K, Tormo, J, Karjalainen, K, Schlievert, P.M, Mariuzza, R.A. | Deposit date: | 2002-01-16 | Release date: | 2002-06-07 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structures of two streptococcal superantigens bound to TCR beta chains reveal diversity in the architecture of T cell signaling complexes. Structure, 10, 2002
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1KLU
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![BU of 1klu by Molmil](/molmil-images/mine/1klu) | Crystal structure of HLA-DR1/TPI(23-37) complexed with staphylococcal enterotoxin C3 variant 3B2 (SEC3-3B2) | Descriptor: | ENTEROTOXIN TYPE C-3, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN, ... | Authors: | Sundberg, E.J, Sawicki, M.W, Andersen, P.S, Sidney, J, Sette, A, Mariuzza, R.A. | Deposit date: | 2001-12-12 | Release date: | 2002-08-02 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Minor structural changes in a mutated human melanoma antigen correspond to dramatically enhanced stimulation of a CD4+ tumor-infiltrating lymphocyte line. J.Mol.Biol., 319, 2002
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1KLG
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![BU of 1klg by Molmil](/molmil-images/mine/1klg) | Crystal structure of HLA-DR1/TPI(23-37, Thr28-->Ile mutant) complexed with staphylococcal enterotoxin C3 variant 3B2 (SEC3-3B2) | Descriptor: | ENTEROTOXIN TYPE C-3, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN, ... | Authors: | Sundberg, E.J, Sawicki, M.W, Andersen, P.S, Sidney, J, Sette, A, Mariuzza, R.A. | Deposit date: | 2001-12-11 | Release date: | 2002-08-02 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Minor structural changes in a mutated human melanoma antigen correspond to dramatically enhanced stimulation of a CD4+ tumor-infiltrating lymphocyte line. J.Mol.Biol., 319, 2002
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1JWU
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![BU of 1jwu by Molmil](/molmil-images/mine/1jwu) | Crystal Structure of the Complex of the MHC Class II Molecule HLA-DR1 (HA peptide 306-318) with the superantigen SEC3 Variant 3B2 | Descriptor: | Enterotoxin type C-3, HA peptide, HLA class II histocompatibility antigen, ... | Authors: | Sundberg, E.J, Andersen, P.S, Schlievert, P.M, Karjalainen, K, Mariuzza, R.A. | Deposit date: | 2001-09-05 | Release date: | 2003-07-08 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural, energetic, and functional analysis of a protein-protein interface at distinct stages of affinity
maturation Structure, 11, 2003
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1JWS
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![BU of 1jws by Molmil](/molmil-images/mine/1jws) | Crystal Structure of the Complex of the MHC Class II Molecule HLA-DR1 (HA peptide 306-318) with the Superantigen SEC3 Variant 3B1 | Descriptor: | Enterotoxin type C-3, HA peptide, HLA class II histocompatibility antigen, ... | Authors: | Sundberg, E.J, Andersen, P.S, Schlievert, P.M, Karjalainen, K, Mariuzza, R.A. | Deposit date: | 2001-09-05 | Release date: | 2003-07-08 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural, energetic, and functional analysis of a protein-protein interface at distinct stages of affinity
maturation Structure, 11, 2003
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1JWM
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![BU of 1jwm by Molmil](/molmil-images/mine/1jwm) | Crystal Structure of the Complex of the MHC Class II Molecule HLA-DR1(HA peptide 306-318) with the Superantigen SEC3 | Descriptor: | Enterotoxin type C-3, HA peptide, HLA class II histocompatibility antigen, ... | Authors: | Sundberg, E.J, Andersen, P.S, Schlievert, P.M, Karjalainen, K, Mariuzza, R.A. | Deposit date: | 2001-09-04 | Release date: | 2003-07-08 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural, energetic, and functional analysis of a protein-protein interface at distinct stages of affinity
maturation Structure, 11, 2003
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