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4SRN
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STRUCTURAL CHANGES THAT ACCOMPANY THE REDUCED CATALYTIC EFFICIENCY OF TWO SEMISYNTHETIC RIBONUCLEASE ANALOGS
Descriptor: RIBONUCLEASE A, SULFATE ION
Authors:deMel, V.S.J, Martin, P.D, Doscher, M.S, Edwards, B.F.P.
Deposit date:1991-05-20
Release date:1994-12-20
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural changes that accompany the reduced catalytic efficiency of two semisynthetic ribonuclease analogs.
J.Biol.Chem., 267, 1992
6XHF
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Structure of Phenylalanyl-5'-O-adenosine phosphoramidate
Descriptor: (2~{S})-2-[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]amino]-3-phenyl-propanoic acid, CHLORIDE ION, Ribonuclease pancreatic
Authors:Pallan, P.S, Egli, M.
Deposit date:2020-06-18
Release date:2021-03-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:The Enzyme-Free Release of Nucleotides from Phosphoramidates Depends Strongly on the Amino Acid.
Angew.Chem.Int.Ed.Engl., 59, 2020
6XHD
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Structure of Prolinyl-5'-O-adenosine phosphoramidate
Descriptor: (2~{S})-1-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]pyrrolidine-2-carboxylic acid, (4S)-2-METHYL-2,4-PENTANEDIOL, POTASSIUM ION, ...
Authors:Pallan, P.S, Egli, M.
Deposit date:2020-06-18
Release date:2021-03-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:The Enzyme-Free Release of Nucleotides from Phosphoramidates Depends Strongly on the Amino Acid.
Angew.Chem.Int.Ed.Engl., 59, 2020
4RSD
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BU of 4rsd by Molmil
STRUCTURE OF THE D121A VARIANT OF RIBONUCLEASE A
Descriptor: ACETATE ION, CHLORIDE ION, RIBONUCLEASE A
Authors:Schultz, L.W, Quirk, D.J, Raines, R.T.
Deposit date:1998-02-05
Release date:1998-07-15
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:His...Asp catalytic dyad of ribonuclease A: structure and function of the wild-type, D121N, and D121A enzymes.
Biochemistry, 37, 1998
4RSK
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BU of 4rsk by Molmil
STRUCTURE OF THE K7A/R10A/K66A VARIANT OF RIBONUCLEASE A COMPLEXED WITH 3'-UMP
Descriptor: 3'-URIDINEMONOPHOSPHATE, RIBONUCLEASE A
Authors:Schultz, L.W, Fisher, B.M, Raines, R.T.
Deposit date:1998-04-09
Release date:1998-12-09
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Coulombic Effects of Remote Subsites on the Active Site of Ribonuclease A
Biochemistry, 37, 1998
4RTE
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BU of 4rte by Molmil
The X-ray structure of bovine pancreatic ribonuclease incubated in the presence of an excess of cisplatin (1:10 ratio)
Descriptor: CHLORIDE ION, Cisplatin, Ribonuclease pancreatic
Authors:Russo Krauss, I, Merlino, A.
Deposit date:2014-11-14
Release date:2015-03-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Platinated oligomers of bovine pancreatic ribonuclease: Structure and stability.
J.Inorg.Biochem., 146, 2015
4S18
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BU of 4s18 by Molmil
The X-ray structure of the adduct formed in the reaction between bovine pancreatic ribonuclease and oxaliplatin
Descriptor: CYCLOHEXANE-1(R),2(R)-DIAMINE-PLATINUM(II), Ribonuclease pancreatic
Authors:Merlino, A.
Deposit date:2015-01-09
Release date:2015-11-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Interactions of carboplatin and oxaliplatin with proteins: Insights from X-ray structures and mass spectrometry studies of their ribonuclease A adducts.
J.Inorg.Biochem., 153, 2015
6XVX
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BU of 6xvx by Molmil
X-ray structure obtained upon reaction of dirhodium tetraacetate with RNase A (high resolution)
Descriptor: ACETATE ION, RHODIUM(III) ION, Ribonuclease pancreatic
Authors:Merlino, A, Ferraro, G.
Deposit date:2020-01-22
Release date:2020-02-19
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Protein interactions of dirhodium tetraacetate: a structural study.
Dalton Trans, 49, 2020
6XHC
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Structure of glycinyl 5'-O-adenosine phosphoramidate
Descriptor: 2-[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]amino]ethanoic acid, Ribonuclease pancreatic
Authors:Pallan, P.S, Egli, M.
Deposit date:2020-06-18
Release date:2020-12-02
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The Enzyme-Free Release of Nucleotides from Phosphoramidates Depends Strongly on the Amino Acid.
Angew.Chem.Int.Ed.Engl., 59, 2020
6YO1
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BU of 6yo1 by Molmil
Crystal structure of ribonuclease A solved by vanadium SAD phasing
Descriptor: Ribonuclease pancreatic, URIDINE-2',3'-VANADATE
Authors:El Omari, K, Mohamad, N, Bountra, K, Duman, R, Romano, M, Schlegel, K, Kwong, H, Mykhaylyk, V, Olesen, C.E, Moller, J.V, Bublitz, M, Beis, K, Wagner, A.
Deposit date:2020-04-14
Release date:2020-11-04
Last modified:2020-12-02
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Experimental phasing with vanadium and application to nucleotide-binding membrane proteins.
Iucrj, 7, 2020
3I7X
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BU of 3i7x by Molmil
High pressure structure of I106A RNase A variant (0.35 GPa)
Descriptor: CHLORIDE ION, Ribonuclease pancreatic
Authors:Lewinski, K, Kurpiewska, K, Dziubek, K, Katrusiak, A, Font, J, Ribo, M, Vilanova, M.
Deposit date:2009-07-09
Release date:2009-08-04
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural investigation of ribonuclease A conformational preferences using high pressure protein crystallography
Chem.Phys., 468, 2016
2KB5
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BU of 2kb5 by Molmil
Solution NMR Structure of Eosinophil Cationic Protein/RNase 3
Descriptor: Eosinophil cationic protein
Authors:Rico, M, Bruix, M, Laurents, D.V, Santoro, J, Jimenez, M, Boix, E, Moussaoui, M, Nogues, M.
Deposit date:2008-11-20
Release date:2009-06-23
Last modified:2021-10-20
Method:SOLUTION NMR
Cite:The (1)H, (13)C, (15)N resonance assignment, solution structure, and residue level stability of eosinophil cationic protein/RNase 3 determined by NMR spectroscopy
Biopolymers, 91, 2009
3U01
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BU of 3u01 by Molmil
Crystal structure of onconase double mutant C30A/C75A at 1.12 A resolution
Descriptor: ACETATE ION, Protein P-30, SULFATE ION
Authors:Kurpiewska, K, Torrent, G, Ribo, M, Vilanova, M, Loch, J, Lewinski, K.
Deposit date:2011-09-28
Release date:2011-12-21
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.12 Å)
Cite:Investigating the effects of double mutation C30A/C75A on onconase structure: Studies at atomic resolution.
Biopolymers, 101, 2014
3I7W
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BU of 3i7w by Molmil
High pressure structure of wild-type RNase A (0.67 GPa)
Descriptor: CHLORIDE ION, Ribonuclease pancreatic
Authors:Lewinski, K, Kurpiewska, K, Dziubek, K, Katrusiak, A, Font, J, Ribo, M, Vilanova, M.
Deposit date:2009-07-09
Release date:2009-08-04
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural investigation of ribonuclease A conformational preferences using high pressure protein crystallography
Chem.Phys., 468, 2016
3JW1
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BU of 3jw1 by Molmil
Crystal Structure of Bovine Pancreatic Ribonuclease Complexed with Uridine-5'-monophosphate at 1.60 A Resolution
Descriptor: Ribonuclease pancreatic, URIDINE-5'-MONOPHOSPHATE
Authors:Larson, S.B, Day, J.S, Nguyen, C, Cudney, R, Mcpherson, A, Center for High-Throughput Structural Biology (CHTSB)
Deposit date:2009-09-17
Release date:2009-10-06
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of bovine pancreatic ribonuclease complexed with uridine 5'-monophosphate at 1.60 A resolution.
Acta Crystallogr.,Sect.F, 66, 2010
7OR6
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BU of 7or6 by Molmil
The crystal structure of the domain-swapped dimer of onconase
Descriptor: Protein P-30
Authors:Merlino, A, Loreto, D.
Deposit date:2021-06-04
Release date:2021-10-06
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:The crystal structure of the domain-swapped dimer of onconase highlights some catalytic and antitumor activity features of the enzyme.
Int.J.Biol.Macromol., 191, 2021
7ORD
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BU of 7ord by Molmil
The crystal structure of the domain-swapped dimer of onconase (2)
Descriptor: ACETATE ION, Protein P-30, SULFATE ION
Authors:Merlino, A, Loreto, D.
Deposit date:2021-06-05
Release date:2021-10-06
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:The crystal structure of the domain-swapped dimer of onconase highlights some catalytic and antitumor activity features of the enzyme.
Int.J.Biol.Macromol., 191, 2021
2W5I
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BU of 2w5i by Molmil
RNASE A-AP3A COMPLEX
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, RIBONUCLEASE PANCREATIC
Authors:Chavali, G.B, Holloway, D.E, Baker, M.D, Acharya, K.R.
Deposit date:2008-12-10
Release date:2009-02-17
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Influence of Naturally-Occurring 5'-Pyrophosphate-Linked Substituents on the Binding of Adenylic Inhibitors to Ribonuclease A: An X-Ray Crystallographic Study.
Biopolymers, 91, 2009
2W5K
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BU of 2w5k by Molmil
RNASE A-NADPH COMPLEX
Descriptor: NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, RIBONUCLEASE PANCREATIC
Authors:Chavali, G.B, Holloway, D.E, Baker, M.D, Acharya, K.R.
Deposit date:2008-12-10
Release date:2009-02-17
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Influence of Naturally-Occurring 5'-Pyrophosphate-Linked Substituents on the Binding of Adenylic Inhibitors to Ribonuclease A: An X-Ray Crystallographic Study.
Biopolymers, 91, 2009
2W5M
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BU of 2w5m by Molmil
RNASE A-PYROPHOSPHATE ION COMPLEX
Descriptor: PYROPHOSPHATE 2-, RIBONUCLEASE PANCREATIC
Authors:Chavali, G.B, Holloway, D.E, Baker, M.D, Acharya, K.R.
Deposit date:2008-12-10
Release date:2009-02-17
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Influence of Naturally-Occurring 5'-Pyrophosphate-Linked Substituents on the Binding of Adenylic Inhibitors to Ribonuclease A: An X-Ray Crystallographic Study.
Biopolymers, 91, 2009
7P8R
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BU of 7p8r by Molmil
X-ray structure of the adduct of a vanadium picolinate complex with RNase A at pH 5.1
Descriptor: Ribonuclease pancreatic, SULFATE ION, hydroxy(oxo)bis(pyridine-2-carboxylato-kappa~2~N,O)vanadium(3+)
Authors:Ferraro, G, Merlino, A.
Deposit date:2021-07-23
Release date:2021-12-22
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.27 Å)
Cite:Spectroscopic/Computational Characterization and the X-ray Structure of the Adduct of the V IV O-Picolinato Complex with RNase A.
Inorg.Chem., 60, 2021
2W5G
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BU of 2w5g by Molmil
RNASE A-5'-ATP COMPLEX
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, RIBONUCLEASE PANCREATIC
Authors:Chavali, G.B, Holloway, D.E, Baker, M.D, Acharya, K.R.
Deposit date:2008-12-10
Release date:2009-02-17
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Influence of Naturally-Occurring 5'-Pyrophosphate- Linked Substituents on the Binding of Adenylic Inhibitors to Ribonuclease A: An X-Ray Crystallographic Study.
Biopolymers, 91, 2009
8OQD
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BU of 8oqd by Molmil
Dirhodium tetraacetate/ribonuclease A adduct in the P3221 space group (1 h soaking)
Descriptor: CHLORIDE ION, FORMIC ACID, Ribonuclease pancreatic, ...
Authors:Loreto, D, Merlino, A, Maity, B, Ueno, T.
Deposit date:2023-04-12
Release date:2023-06-14
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Cross-Linked Crystals of Dirhodium Tetraacetate/RNase A Adduct Can Be Used as Heterogeneous Catalysts.
Inorg.Chem., 62, 2023
8OQE
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Dirhodium tetraacetate/ribonuclease A adduct in the P3221 space group (6 h soaking)
Descriptor: CHLORIDE ION, FORMIC ACID, Ribonuclease pancreatic, ...
Authors:Loreto, D, Merlino, A, Maity, B, Ueno, T.
Deposit date:2023-04-12
Release date:2023-06-14
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Cross-Linked Crystals of Dirhodium Tetraacetate/RNase A Adduct Can Be Used as Heterogeneous Catalysts.
Inorg.Chem., 62, 2023
8OQF
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BU of 8oqf by Molmil
Cross-linked crystal of Dirhodium tetraacetate/ribonuclease A adduct in the P3221 space group (low temperature data collection)
Descriptor: (mi2-acetato-O, O')-hexaaquo-dirhodium (II), CHLORIDE ION, ...
Authors:Loreto, D, Merlino, A, Maity, B, Ueno, T.
Deposit date:2023-04-12
Release date:2023-06-14
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Cross-Linked Crystals of Dirhodium Tetraacetate/RNase A Adduct Can Be Used as Heterogeneous Catalysts.
Inorg.Chem., 62, 2023

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数据于2024-06-19公开中

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