PDB: 5653 resultsInfo pagesStatus searchChemie searchBIRD

---

7NY0	Solution structure of Boskar4; a de novo designed G-CSF agonist Descriptor: Boskar4 Authors: ElGamacy, M, Coles, M. Deposit date: 2021-03-19 Release date: 2021-10-06 Last modified: 2024-06-19 Method: SOLUTION NMR Cite: A topological refactoring design strategy yields highly stable granulopoietic proteins. Nat Commun, 13, 2022
7DZE	Fabp ground state captured by XFELs Descriptor: Fatty acid-binding protein, liver, PALMITIC ACID Authors: Li, H, Yu, L.-J, Liu, X, Shen, J.-R, Wang, J. Deposit date: 2021-01-25 Release date: 2022-07-27 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser. Nat.Chem., 14, 2022
7DZH	intermediate of FABP with a delay time of 100 ns Descriptor: Fatty acid-binding protein, liver, PALMITIC ACID Authors: Li, H, Yu, L.-J, Liu, X, Shen, J.-R, Wang, J. Deposit date: 2021-01-25 Release date: 2022-07-27 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser. Nat.Chem., 14, 2022
7DZF	Intermediate of FABP with a delay time of 10 ns Descriptor: Fatty acid-binding protein, liver, PALMITIC ACID Authors: Li, H, Yu, L.-J, Liu, X, Shen, J.-R, Wang, J. Deposit date: 2021-01-25 Release date: 2022-07-27 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser. Nat.Chem., 14, 2022
7DZG	Intermediate of FABP with a delay time of 30 ns Descriptor: Fatty acid-binding protein, liver, PALMITIC ACID Authors: Li, H, Yu, L.-J, Liu, X, Shen, J.-R, Wang, J. Deposit date: 2021-01-25 Release date: 2022-07-27 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser. Nat.Chem., 14, 2022
7DZI	intermediate of FABP with a delay time of 300 ns Descriptor: Fatty acid-binding protein, liver, PALMITIC ACID Authors: Li, H, Yu, L.-J, Liu, X, Shen, J.-R, Wang, J. Deposit date: 2021-01-25 Release date: 2022-07-27 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser. Nat.Chem., 14, 2022
7DZJ	Fabp protein before hv Descriptor: Fatty acid-binding protein, liver, PALMITIC ACID Authors: Li, H, Yu, L.-J, Liu, X, Shen, J.-R, Wang, J. Deposit date: 2021-01-25 Release date: 2022-07-27 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.63 Å) Cite: Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser. Nat.Chem., 14, 2022
7DZK	Fabp protein after hv Descriptor: Fatty acid-binding protein, liver, PALMITIC ACID Authors: Li, H, Yu, L.-J, Liu, X, Shen, J.-R, Wang, J. Deposit date: 2021-01-25 Release date: 2022-07-27 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.54 Å) Cite: Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser. Nat.Chem., 14, 2022
7DZL	A69C-M71L mutant of Fabp protein Descriptor: Fatty acid-binding protein, liver, PALMITIC ACID Authors: Li, H, Yu, L.-J, Liu, X, Shen, J.-R, Wang, J. Deposit date: 2021-01-25 Release date: 2022-07-27 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.64 Å) Cite: Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser. Nat.Chem., 14, 2022
4Q4Z	Thermus thermophilus RNA polymerase de novo transcription initiation complex Descriptor: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, ADENOSINE-5'-TRIPHOSPHATE, DNA (25-MER), ... Authors: Murakami, K.S. Deposit date: 2014-04-15 Release date: 2014-07-30 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structural basis of transcription initiation by bacterial RNA polymerase holoenzyme. J.Biol.Chem., 289, 2014
4LOA	X-ray structure of the de-novo design amidase at the resolution 1.8A, Northeast Structural Genomics Consortium (NESG) Target OR398 Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, De-novo design amidase Authors: Kuzin, A, Lew, S, Vorobiev, S.M, Seetharaman, J, Sahdev, S, Xiao, R, Maglaqui, M, Kogan, S, Khersonsky, O, Everett, J.K, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) Deposit date: 2013-07-12 Release date: 2013-08-07 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (1.819 Å) Cite: Northeast Structural Genomics Consortium Target OR398 To be Published
6EGO	Crystal Structure of a de Novo Three-stranded Coiled Coil Peptide Containing an Ala Residue in the Second Coordination Sphere of the Hg(II)S3 Binding Site Descriptor: Hg(II)(GRAND CoilSerL12AL16C)3-, MERCURY (II) ION, ZINC ION Authors: Ruckthong, L, Stuckey, J.A, Pecoraro, V.L. Deposit date: 2018-08-20 Release date: 2019-04-03 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.93 Å) Cite: How Outer Coordination Sphere Modifications Can Impact Metal Structures in Proteins: A Crystallographic Evaluation. Chemistry, 25, 2019
6EGL	Crystal Structure of a de Novo Three-stranded Coiled Coil Peptide Containing a D-Leu in the Second Coordination Sphere of a Non-metalated Tris-thiolate Binding Site Descriptor: Apo-(GRAND CoilSerL12(DLE)L16C)3, POLYETHYLENE GLYCOL (N=34), ZINC ION Authors: Ruckthong, L, Stuckey, J.A, Pecoraro, V.L. Deposit date: 2018-08-20 Release date: 2019-04-03 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.4 Å) Cite: How Outer Coordination Sphere Modifications Can Impact Metal Structures in Proteins: A Crystallographic Evaluation. Chemistry, 25, 2019
6TVJ	Solution structure of PD-i3 peptide inhibitor of the human PD-1 extracellular domain Descriptor: PD-i3 peptide Authors: Guardiola, S, Varese, M, Garcia, J, Giralt, E. Deposit date: 2020-01-09 Release date: 2021-01-27 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Target-templated de novo design of macrocyclic d-/l-peptides: discovery of drug-like inhibitors of PD-1. Chem Sci, 12, 2021
6UTV	E. coli sigma-S transcription initiation complex with a 6-nt RNA ("Fresh" crystal soaked with CTP, UTP, GTP, and ddATP for 150 seconds) Descriptor: DIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Zuo, Y, De, S, Steitz, T.A. Deposit date: 2019-10-30 Release date: 2020-08-26 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.45 Å) Cite: Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
6UUA	E. coli sigma-S transcription initiation complex with a mismatching CTP ("Fresh" crystal soaked with CTP for 2 hours) Descriptor: CYTIDINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Zuo, Y, De, S, Steitz, T.A. Deposit date: 2019-10-30 Release date: 2020-08-26 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (4.002 Å) Cite: Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
6UU3	E. coli sigma-S transcription initiation complex with a 4-nt RNA and a CTP ("Old" crystal soaked with GTP, ATP, CTP, and ddTTP for 30 minutes) Descriptor: CYTIDINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Zuo, Y, De, S, Steitz, T.A. Deposit date: 2019-10-30 Release date: 2020-08-26 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (4.002 Å) Cite: Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
6UU6	E. coli sigma-S transcription initiation complex with a 4-nt RNA and a UTP ("Old" crystal soaked with UTP, ddCTP, and dinucleotide ApG for 30 minutes) Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Zuo, Y, De, S, Steitz, T.A. Deposit date: 2019-10-30 Release date: 2020-08-26 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (4.201 Å) Cite: Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
6UU1	E. coli sigma-S transcription initiation complex with a 4-nt RNA and a CTP ("Fresh" crystal soaked with CTP, GTP, and ddTTP for 30 minutes) Descriptor: CYTIDINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Zuo, Y, De, S, Steitz, T.A. Deposit date: 2019-10-30 Release date: 2020-08-26 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (4.097 Å) Cite: Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
6UTZ	E. coli sigma-S transcription initiation complex with a 6-nt RNA ("Fresh" crystal soaked with CTP and UTP for 30 minutes) Descriptor: DIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Zuo, Y, De, S, Steitz, T.A. Deposit date: 2019-10-30 Release date: 2020-08-26 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.803 Å) Cite: Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
6UTY	E. coli sigma-S transcription initiation complex with a mismatching CTP ("Old" crystal soaked with CTP for 30 minutes) Descriptor: CYTIDINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Zuo, Y, De, S, Steitz, T.A. Deposit date: 2019-10-30 Release date: 2020-08-26 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (4.15 Å) Cite: Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
6UTX	E. coli sigma-S transcription initiation complex with an empty bubble ("Old" crystal) Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Zuo, Y, De, S, Steitz, T.A. Deposit date: 2019-10-30 Release date: 2020-08-26 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (4.05 Å) Cite: Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
6UUB	E. coli sigma-S transcription initiation complex with a mismatching UTP ("Fresh" crystal soaked with UTP for 2 hours) Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Zuo, Y, De, S, Steitz, T.A. Deposit date: 2019-10-30 Release date: 2020-08-26 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.955 Å) Cite: Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
6UU9	E. coli mutant sigma-S transcription initiation complex with an 8-nt RNA ("Fresh" mutant crystal soaked with GTP, UTP, CTP, and ddATP for 30 minutes) Descriptor: 2',3'-DIDEOXYADENOSINE-5'-MONOPHOSPHATE, DIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, ... Authors: Zuo, Y, De, S, Steitz, T.A. Deposit date: 2019-10-30 Release date: 2020-08-26 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (5.4 Å) Cite: Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
6UU2	E. coli sigma-S transcription initiation complex with 3-nt RNA ("Old" crystal soaked with GTP and ATP for 30 minutes) Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Zuo, Y, De, S, Steitz, T.A. Deposit date: 2019-10-30 Release date: 2020-08-26 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (4.404 Å) Cite: Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020

<31323334353637383940414243444546>