7NY0

Solution structure of Boskar4; a de novo designed G-CSF agonist

Summary for 7NY0

• Entry DOI: 10.2210/pdb7ny0/pdb
• NMR Information: BMRB: 34613
• Descriptor: Boskar4 (1 entity in total)
• Functional Keywords: protein design, g-csf agonist, four-helix bundle, de novo protein
• Biological source: synthetic construct
• Total number of polymer chains: 1
• Total formula weight: 13014.96

Authors

ElGamacy, M.,Coles, M. (deposition date: 2021-03-19, release date: 2021-10-06, Last modification date: 2022-06-08)

• Primary citation: Skokowa, J.,Hernandez Alvarez, B.,Coles, M.,Ritter, M.,Nasri, M.,Haaf, J.,Aghaallaei, N.,Xu, Y.,Mir, P.,Krahl, A.C.,Rogers, K.W.,Maksymenko, K.,Bajoghli, B.,Welte, K.,Lupas, A.N.,Muller, P.,ElGamacy, M.; A topological refactoring design strategy yields highly stable granulopoietic proteins.; Nat Commun, 13:2948-2948, 2022; PubMed: 35618709; DOI: 10.1038/s41467-022-30157-2

Experimental method

SOLUTION NMR