4DUZ
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![BU of 4duz by Molmil](/molmil-images/mine/4duz) | Crystal structure of the Thermus thermophilus 30S ribosomal subunit with a 16S rRNA mutation, U13C, bound with streptomycin | Descriptor: | 16S rRNA, MAGNESIUM ION, STREPTOMYCIN, ... | Authors: | Demirci, H, Murphy IV, F, Murphy, E, Gregory, S.T, Dahlberg, A.E, Jogl, G. | Deposit date: | 2012-02-22 | Release date: | 2013-02-27 | Method: | X-RAY DIFFRACTION (3.651 Å) | Cite: | A structural basis for streptomycin resistance To be Published
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4DAF
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![BU of 4daf by Molmil](/molmil-images/mine/4daf) | Crystal structure of B. anthracis DHPS with compound 19 | Descriptor: | (2R)-2-(7-amino-4,5-dioxo-1,4,5,6-tetrahydropyrimido[4,5-c]pyridazin-3-yl)propanoic acid, Dihydropteroate Synthase, SULFATE ION | Authors: | Hammoudeh, D, Lee, R.E, White, S.W. | Deposit date: | 2012-01-12 | Release date: | 2012-04-04 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.501 Å) | Cite: | Structure-Based Design of Novel Pyrimido[4,5-c]pyridazine Derivatives as Dihydropteroate Synthase Inhibitors with Increased Affinity. Chemmedchem, 7, 2012
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3Q6P
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![BU of 3q6p by Molmil](/molmil-images/mine/3q6p) | Salivary protein from Lutzomyia longipalpis. Selenomethionine derivative | Descriptor: | 43.2 kDa salivary protein, CITRIC ACID | Authors: | Andersen, J.F, Xu, X, Chang, B.W, Collin, N, Valenzuela, J.G, Ribeiro, J.M. | Deposit date: | 2011-01-03 | Release date: | 2011-07-27 | Last modified: | 2019-10-23 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structure and function of a "yellow" protein from saliva of the sand fly Lutzomyia longipalpis that confers protective immunity against Leishmania major infection. J.Biol.Chem., 286, 2011
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2OFX
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4I2V
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![BU of 4i2v by Molmil](/molmil-images/mine/4i2v) | X-ray structure of the unliganded uridine phosphorylase from Yersinia pseudotuberculosis at 2.12A resolution | Descriptor: | Uridine phosphorylase | Authors: | Lashkov, A.A, Balaev, V.V, Prokofev, I.I, Betzel, C, Gabdoulkhakov, A.G, Mikhailov, A.M. | Deposit date: | 2012-11-23 | Release date: | 2013-12-18 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.121 Å) | Cite: | X-ray structure of the unliganded uridine phosphorylase from Yersinia pseudotuberculosis at 2.12A resolution To be Published
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4DAU
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4DX3
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![BU of 4dx3 by Molmil](/molmil-images/mine/4dx3) | Crystal structure of an enolase (mandelate racemase subgroup, target EFI-502086) from Agrobacterium tumefaciens, with a succinimide residue | Descriptor: | CHLORIDE ION, GLYCEROL, Mandelate racemase / muconate lactonizing enzyme family protein | Authors: | Vetting, M.W, Bouvier, J.T, Toro, R, Bhosle, R, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | Deposit date: | 2012-02-27 | Release date: | 2012-04-18 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Crystal structure of an enolase (mandelate racemase subgroup, target EFI-502086) from Agrobacterium tumefaciens, with a succinimide residue to be published
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3Q80
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![BU of 3q80 by Molmil](/molmil-images/mine/3q80) | Structure of Mtb 2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (IspD) Complexed with CDP-ME | Descriptor: | 2-C-methyl-D-erythritol 4-phosphate cytidyltransferase, 4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL, CHLORIDE ION, ... | Authors: | Reddy, M.C.M, Bruning, J.B, Thurman, C, Ioerger, T.R, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2011-01-05 | Release date: | 2011-05-04 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of Mycobacterium tuberculosis 2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (IspD): a candidate antitubercular drug target Proteins, 2011
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3Q8M
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![BU of 3q8m by Molmil](/molmil-images/mine/3q8m) | Crystal Structure of Human Flap Endonuclease FEN1 (D181A) in complex with substrate 5'-flap DNA and K+ | Descriptor: | DNA (5'-D(*AP*CP*CP*GP*TP*CP*C)-3'), DNA (5'-D(*AP*CP*TP*CP*TP*GP*CP*CP*TP*CP*AP*AP*GP*AP*CP*GP*GP*T)-3'), DNA (5'-D(*TP*TP*GP*AP*GP*GP*CP*AP*GP*AP*GP*T)-3'), ... | Authors: | Tsutakawa, S.E, Classen, S, Chapados, B.R, Arvai, A, Finger, D.L, Guenther, G, Tomlinson, C.G, Thompson, P, Sarker, A.H, Shen, B, Cooper, P.K, Grasby, J.A, Tainer, J.A. | Deposit date: | 2011-01-06 | Release date: | 2011-04-27 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Human Flap Endonuclease Structures, DNA Double-Base Flipping, and a Unified Understanding of the FEN1 Superfamily. Cell(Cambridge,Mass.), 145, 2011
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3Q5Z
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2OGZ
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![BU of 2ogz by Molmil](/molmil-images/mine/2ogz) | Crystal structure of DPP-IV complexed with Lilly aryl ketone inhibitor | Descriptor: | 4-[(3R)-3-{[2-(4-FLUOROPHENYL)-2-OXOETHYL]AMINO}BUTYL]BENZAMIDE, Dipeptidyl peptidase | Authors: | Timm, D.E. | Deposit date: | 2007-01-09 | Release date: | 2007-03-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Discovery of non-covalent dipeptidyl peptidase IV inhibitors which induce a conformational change in the active site. Bioorg.Med.Chem.Lett., 17, 2007
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4DYS
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![BU of 4dys by Molmil](/molmil-images/mine/4dys) | Crystal Structure of Apo Swine Flu Influenza Nucleoprotein | Descriptor: | Nucleocapsid protein | Authors: | Lewis, H.A, Baldwin, E.T, Steinbacher, S, Maskos, K, Mortl, M, Kiefersauer, R, Edavettal, S, McDonnell, P.A, Pearce, B.C, Langley, D.R. | Deposit date: | 2012-02-29 | Release date: | 2013-03-06 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | To be determined To be Published
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2OHY
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3Q81
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![BU of 3q81 by Molmil](/molmil-images/mine/3q81) | Imipenem acylated BlaR1 sensor domain from Staphylococcus aureus | Descriptor: | (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carboxylic acid, Beta-lactamase regulatory protein BlaR1, GLYCEROL | Authors: | Borbulevych, O.Y, Mobashery, S, Baker, B.M. | Deposit date: | 2011-01-05 | Release date: | 2011-07-20 | Last modified: | 2013-01-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Lysine Nzeta-decarboxylation switch and activation of the beta-lactam sensor domain of BlaR1 protein of methicillin-resistant Staphylococcus aureus. J.Biol.Chem., 286, 2011
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2NWG
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![BU of 2nwg by Molmil](/molmil-images/mine/2nwg) | Structure of CXCL12:heparin disaccharide complex | Descriptor: | 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, Stromal cell-derived factor 1 | Authors: | Murphy, J.W, Cho, Y, Lolis, E. | Deposit date: | 2006-11-14 | Release date: | 2007-02-13 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | Structural and Functional Basis of CXCL12 (Stromal Cell-derived Factor-1{alpha}) Binding to Heparin J.Biol.Chem., 282, 2007
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3QBN
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3Q8F
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![BU of 3q8f by Molmil](/molmil-images/mine/3q8f) | Crystal structure of 2-Fluorohistine labeled Protective Antigen (pH 5.8) | Descriptor: | CALCIUM ION, Protective antigen, TETRAETHYLENE GLYCOL | Authors: | Lovell, S, Battaile, K.P, Rajapaksha, M, Janowiak, B.E, Andra, K.K, Bann, J.G. | Deposit date: | 2011-01-06 | Release date: | 2012-02-15 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | pH effects on binding between the anthrax protective antigen and the host cellular receptor CMG2. Protein Sci., 21, 2012
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4DGD
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![BU of 4dgd by Molmil](/molmil-images/mine/4dgd) | TRIMCyp cyclophilin domain from Macaca mulatta: H70C mutant | Descriptor: | GLYCEROL, TRIMCyp | Authors: | Caines, M.E.C, Bichel, K, Price, A.J, McEwan, W.A, James, L.C. | Deposit date: | 2012-01-25 | Release date: | 2012-02-08 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Diverse HIV viruses are targeted by a conformationally dynamic antiviral. Nat.Struct.Mol.Biol., 19, 2012
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4I4L
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![BU of 4i4l by Molmil](/molmil-images/mine/4i4l) | Crystal Structure of Nucleotide-Bound W-W-W ClpX Hexamer | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, SULFATE ION | Authors: | Glynn, S.E, Nager, A.R, Stinson, B.S, Schmitz, K.R, Baker, T.A, Sauer, R.T. | Deposit date: | 2012-11-27 | Release date: | 2013-05-15 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.6981 Å) | Cite: | Nucleotide Binding and Conformational Switching in the Hexameric Ring of a AAA+ Machine. Cell(Cambridge,Mass.), 153, 2013
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3QCW
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![BU of 3qcw by Molmil](/molmil-images/mine/3qcw) | Structure of neurexin 1 alpha (domains LNS1-LNS6), no splice inserts | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Neurexin-1-alpha | Authors: | Rudenko, G. | Deposit date: | 2011-01-17 | Release date: | 2011-06-15 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | The Structure of Neurexin 1 alpha Reveals Features Promoting a Role as Synaptic Organizer Structure, 19, 2011
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4E18
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![BU of 4e18 by Molmil](/molmil-images/mine/4e18) | Alpha-E-catenin is an autoinhibited molecule that co-activates vinculin | Descriptor: | Catenin alpha-1, Vinculin | Authors: | Choi, H.-J, Pokutta, S, Cadwell, G.W, Bankston, L.A, Liddington, R.C, Weis, W.I. | Deposit date: | 2012-03-05 | Release date: | 2012-05-16 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.403 Å) | Cite: | Conformational plasticity of alpha-catenin revealed by binding interactions with vinculin To be Published
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3QEC
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3EVN
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![BU of 3evn by Molmil](/molmil-images/mine/3evn) | CRYSTAL STRUCTURE OF putative oxidoreductase from Streptococcus agalactiae 2603V/r | Descriptor: | Oxidoreductase, Gfo/Idh/MocA family | Authors: | Malashkevich, V.N, Toro, R, Meyer, A.J, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2008-10-13 | Release date: | 2008-10-21 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | CRYSTAL STRUCTURE OF putative Gfo/Idh/MocA family oxidoreductase from Streptococcus agalactiae
2603V/r To be Published
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4IBN
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![BU of 4ibn by Molmil](/molmil-images/mine/4ibn) | Crystal structure of LC9-RNase H1, a type 1 RNase H with the type 2 active-site motif | Descriptor: | Ribonuclease H | Authors: | Nguyen, T.-N, You, D.-J, Kanaya, E, Koga, Y, Kanaya, S. | Deposit date: | 2012-12-09 | Release date: | 2013-03-20 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Crystal structure of metagenome-derived LC9-RNase H1 with atypical DEDN active site motif Febs Lett., 587, 2013
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3QC2
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