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4DUZ
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BU of 4duz by Molmil
Crystal structure of the Thermus thermophilus 30S ribosomal subunit with a 16S rRNA mutation, U13C, bound with streptomycin
Descriptor: 16S rRNA, MAGNESIUM ION, STREPTOMYCIN, ...
Authors:Demirci, H, Murphy IV, F, Murphy, E, Gregory, S.T, Dahlberg, A.E, Jogl, G.
Deposit date:2012-02-22
Release date:2013-02-27
Method:X-RAY DIFFRACTION (3.651 Å)
Cite:A structural basis for streptomycin resistance
To be Published
4DAF
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BU of 4daf by Molmil
Crystal structure of B. anthracis DHPS with compound 19
Descriptor: (2R)-2-(7-amino-4,5-dioxo-1,4,5,6-tetrahydropyrimido[4,5-c]pyridazin-3-yl)propanoic acid, Dihydropteroate Synthase, SULFATE ION
Authors:Hammoudeh, D, Lee, R.E, White, S.W.
Deposit date:2012-01-12
Release date:2012-04-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.501 Å)
Cite:Structure-Based Design of Novel Pyrimido[4,5-c]pyridazine Derivatives as Dihydropteroate Synthase Inhibitors with Increased Affinity.
Chemmedchem, 7, 2012
3Q6P
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BU of 3q6p by Molmil
Salivary protein from Lutzomyia longipalpis. Selenomethionine derivative
Descriptor: 43.2 kDa salivary protein, CITRIC ACID
Authors:Andersen, J.F, Xu, X, Chang, B.W, Collin, N, Valenzuela, J.G, Ribeiro, J.M.
Deposit date:2011-01-03
Release date:2011-07-27
Last modified:2019-10-23
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structure and function of a "yellow" protein from saliva of the sand fly Lutzomyia longipalpis that confers protective immunity against Leishmania major infection.
J.Biol.Chem., 286, 2011
2OFX
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BU of 2ofx by Molmil
crystal structure of the APSK domain of human PAPSS1 in complex with ADPMg and PAPS
Descriptor: 3'-PHOSPHATE-ADENOSINE-5'-PHOSPHATE SULFATE, ADENOSINE-5'-DIPHOSPHATE, Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 1, ...
Authors:Sekulic, N, Lavie, A.
Deposit date:2007-01-04
Release date:2007-04-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Elucidation of the Active Conformation of the APS-Kinase Domain of Human PAPS Synthetase 1.
J.Mol.Biol., 367, 2007
4I2V
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BU of 4i2v by Molmil
X-ray structure of the unliganded uridine phosphorylase from Yersinia pseudotuberculosis at 2.12A resolution
Descriptor: Uridine phosphorylase
Authors:Lashkov, A.A, Balaev, V.V, Prokofev, I.I, Betzel, C, Gabdoulkhakov, A.G, Mikhailov, A.M.
Deposit date:2012-11-23
Release date:2013-12-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.121 Å)
Cite:X-ray structure of the unliganded uridine phosphorylase from Yersinia pseudotuberculosis at 2.12A resolution
To be Published
4DAU
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BU of 4dau by Molmil
Structure of 14-3-3 sigma in complex with PADI6 14-3-3 binding motif I
Descriptor: 14-3-3 protein sigma, Peptidylarginine Deiminase type VI
Authors:Rose, R, Rose, M, Ottmann, C.
Deposit date:2012-01-13
Release date:2012-06-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Identification and structural characterization of two 14-3-3 binding sites in the human peptidylarginine deiminase type VI.
J.Struct.Biol., 180, 2012
4DX3
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BU of 4dx3 by Molmil
Crystal structure of an enolase (mandelate racemase subgroup, target EFI-502086) from Agrobacterium tumefaciens, with a succinimide residue
Descriptor: CHLORIDE ION, GLYCEROL, Mandelate racemase / muconate lactonizing enzyme family protein
Authors:Vetting, M.W, Bouvier, J.T, Toro, R, Bhosle, R, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI)
Deposit date:2012-02-27
Release date:2012-04-18
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of an enolase (mandelate racemase subgroup, target EFI-502086) from Agrobacterium tumefaciens, with a succinimide residue
to be published
3Q80
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BU of 3q80 by Molmil
Structure of Mtb 2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (IspD) Complexed with CDP-ME
Descriptor: 2-C-methyl-D-erythritol 4-phosphate cytidyltransferase, 4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL, CHLORIDE ION, ...
Authors:Reddy, M.C.M, Bruning, J.B, Thurman, C, Ioerger, T.R, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
Deposit date:2011-01-05
Release date:2011-05-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of Mycobacterium tuberculosis 2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (IspD): a candidate antitubercular drug target
Proteins, 2011
3Q8M
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BU of 3q8m by Molmil
Crystal Structure of Human Flap Endonuclease FEN1 (D181A) in complex with substrate 5'-flap DNA and K+
Descriptor: DNA (5'-D(*AP*CP*CP*GP*TP*CP*C)-3'), DNA (5'-D(*AP*CP*TP*CP*TP*GP*CP*CP*TP*CP*AP*AP*GP*AP*CP*GP*GP*T)-3'), DNA (5'-D(*TP*TP*GP*AP*GP*GP*CP*AP*GP*AP*GP*T)-3'), ...
Authors:Tsutakawa, S.E, Classen, S, Chapados, B.R, Arvai, A, Finger, D.L, Guenther, G, Tomlinson, C.G, Thompson, P, Sarker, A.H, Shen, B, Cooper, P.K, Grasby, J.A, Tainer, J.A.
Deposit date:2011-01-06
Release date:2011-04-27
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Human Flap Endonuclease Structures, DNA Double-Base Flipping, and a Unified Understanding of the FEN1 Superfamily.
Cell(Cambridge,Mass.), 145, 2011
3Q5Z
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BU of 3q5z by Molmil
Crystal structure of virulent allele ROP5B pseudokinase domain
Descriptor: 1,2-ETHANEDIOL, ROP5B
Authors:Reese, M.L, Boothroyd, J.C.
Deposit date:2010-12-30
Release date:2011-02-23
Last modified:2012-02-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A conserved non-canonical motif in the pseudoactive site of the ROP5 pseudokinase domain mediates its effect on Toxoplasma virulence.
J.Biol.Chem., 286, 2011
2OGZ
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BU of 2ogz by Molmil
Crystal structure of DPP-IV complexed with Lilly aryl ketone inhibitor
Descriptor: 4-[(3R)-3-{[2-(4-FLUOROPHENYL)-2-OXOETHYL]AMINO}BUTYL]BENZAMIDE, Dipeptidyl peptidase
Authors:Timm, D.E.
Deposit date:2007-01-09
Release date:2007-03-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Discovery of non-covalent dipeptidyl peptidase IV inhibitors which induce a conformational change in the active site.
Bioorg.Med.Chem.Lett., 17, 2007
4DYS
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BU of 4dys by Molmil
Crystal Structure of Apo Swine Flu Influenza Nucleoprotein
Descriptor: Nucleocapsid protein
Authors:Lewis, H.A, Baldwin, E.T, Steinbacher, S, Maskos, K, Mortl, M, Kiefersauer, R, Edavettal, S, McDonnell, P.A, Pearce, B.C, Langley, D.R.
Deposit date:2012-02-29
Release date:2013-03-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:To be determined
To be Published
2OHY
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BU of 2ohy by Molmil
X-ray Crystal Structure of Tyrosine Aminomutase from streptomyces globisporus
Descriptor: Tyrosine aminomutase
Authors:Christianson, C, Bruner, S.
Deposit date:2007-01-10
Release date:2007-06-12
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The structure of L-tyrosine 2,3-aminomutase from the C-1027 enediyne antitumor antibiotic biosynthetic pathway
Biochemistry, 46, 2007
3Q81
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BU of 3q81 by Molmil
Imipenem acylated BlaR1 sensor domain from Staphylococcus aureus
Descriptor: (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carboxylic acid, Beta-lactamase regulatory protein BlaR1, GLYCEROL
Authors:Borbulevych, O.Y, Mobashery, S, Baker, B.M.
Deposit date:2011-01-05
Release date:2011-07-20
Last modified:2013-01-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Lysine Nzeta-decarboxylation switch and activation of the beta-lactam sensor domain of BlaR1 protein of methicillin-resistant Staphylococcus aureus.
J.Biol.Chem., 286, 2011
2NWG
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BU of 2nwg by Molmil
Structure of CXCL12:heparin disaccharide complex
Descriptor: 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, Stromal cell-derived factor 1
Authors:Murphy, J.W, Cho, Y, Lolis, E.
Deposit date:2006-11-14
Release date:2007-02-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Structural and Functional Basis of CXCL12 (Stromal Cell-derived Factor-1{alpha}) Binding to Heparin
J.Biol.Chem., 282, 2007
3QBN
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BU of 3qbn by Molmil
Structure of Human Aurora A in Complex with a diaminopyrimidine
Descriptor: 5-chloro-N~4~-cyclopropyl-N~2~-[4-(2-methoxyethoxy)phenyl]pyrimidine-2,4-diamine, Serine/threonine-protein kinase 6
Authors:Gruetter, C, Simard, J.R, Rauh, D.
Deposit date:2011-01-13
Release date:2012-01-18
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Identification of Ustilago maydis Aurora kinase as a novel antifungal target.
Acs Chem.Biol., 6, 2011
3Q8F
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BU of 3q8f by Molmil
Crystal structure of 2-Fluorohistine labeled Protective Antigen (pH 5.8)
Descriptor: CALCIUM ION, Protective antigen, TETRAETHYLENE GLYCOL
Authors:Lovell, S, Battaile, K.P, Rajapaksha, M, Janowiak, B.E, Andra, K.K, Bann, J.G.
Deposit date:2011-01-06
Release date:2012-02-15
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:pH effects on binding between the anthrax protective antigen and the host cellular receptor CMG2.
Protein Sci., 21, 2012
4DGD
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BU of 4dgd by Molmil
TRIMCyp cyclophilin domain from Macaca mulatta: H70C mutant
Descriptor: GLYCEROL, TRIMCyp
Authors:Caines, M.E.C, Bichel, K, Price, A.J, McEwan, W.A, James, L.C.
Deposit date:2012-01-25
Release date:2012-02-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Diverse HIV viruses are targeted by a conformationally dynamic antiviral.
Nat.Struct.Mol.Biol., 19, 2012
4I4L
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BU of 4i4l by Molmil
Crystal Structure of Nucleotide-Bound W-W-W ClpX Hexamer
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, SULFATE ION
Authors:Glynn, S.E, Nager, A.R, Stinson, B.S, Schmitz, K.R, Baker, T.A, Sauer, R.T.
Deposit date:2012-11-27
Release date:2013-05-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.6981 Å)
Cite:Nucleotide Binding and Conformational Switching in the Hexameric Ring of a AAA+ Machine.
Cell(Cambridge,Mass.), 153, 2013
3QCW
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BU of 3qcw by Molmil
Structure of neurexin 1 alpha (domains LNS1-LNS6), no splice inserts
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Neurexin-1-alpha
Authors:Rudenko, G.
Deposit date:2011-01-17
Release date:2011-06-15
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:The Structure of Neurexin 1 alpha Reveals Features Promoting a Role as Synaptic Organizer
Structure, 19, 2011
4E18
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BU of 4e18 by Molmil
Alpha-E-catenin is an autoinhibited molecule that co-activates vinculin
Descriptor: Catenin alpha-1, Vinculin
Authors:Choi, H.-J, Pokutta, S, Cadwell, G.W, Bankston, L.A, Liddington, R.C, Weis, W.I.
Deposit date:2012-03-05
Release date:2012-05-16
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.403 Å)
Cite:Conformational plasticity of alpha-catenin revealed by binding interactions with vinculin
To be Published
3QEC
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BU of 3qec by Molmil
Crystal structure of a putative carbohydrate binding protein (PA1324) from Pseudomonas aeruginosa at 2.61 A resolution
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, Putative carbohydrate binding protein, ...
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2011-01-20
Release date:2011-03-02
Last modified:2023-02-01
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Crystal structure of a putative carbohydrate binding protein (PA1324) from Pseudomonas aeruginosa at 2.61 A resolution
To be published
3EVN
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BU of 3evn by Molmil
CRYSTAL STRUCTURE OF putative oxidoreductase from Streptococcus agalactiae 2603V/r
Descriptor: Oxidoreductase, Gfo/Idh/MocA family
Authors:Malashkevich, V.N, Toro, R, Meyer, A.J, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2008-10-13
Release date:2008-10-21
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:CRYSTAL STRUCTURE OF putative Gfo/Idh/MocA family oxidoreductase from Streptococcus agalactiae 2603V/r
To be Published
4IBN
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BU of 4ibn by Molmil
Crystal structure of LC9-RNase H1, a type 1 RNase H with the type 2 active-site motif
Descriptor: Ribonuclease H
Authors:Nguyen, T.-N, You, D.-J, Kanaya, E, Koga, Y, Kanaya, S.
Deposit date:2012-12-09
Release date:2013-03-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Crystal structure of metagenome-derived LC9-RNase H1 with atypical DEDN active site motif
Febs Lett., 587, 2013
3QC2
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BU of 3qc2 by Molmil
Crystal structure of a glycosyl hydrolase (BACOVA_03624) from Bacteroides ovatus at 2.30 A resolution
Descriptor: DI(HYDROXYETHYL)ETHER, TRIETHYLENE GLYCOL, glycosyl hydrolase
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2011-01-14
Release date:2011-02-09
Last modified:2023-02-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of a glycosyl hydrolase (BACOVA_03624) from Bacteroides ovatus at 2.30 A resolution
To be published

223790

数据于2024-08-14公开中

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