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3ICK
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BU of 3ick by Molmil
Trypanosoma cruzi farnesyl diphosphate synthase homodimer in complex with minodronate and isopentenyl disphosphate
Descriptor: (1-HYDROXY-2-IMIDAZO[1,2-A]PYRIDIN-3-YLETHANE-1,1-DIYL)BIS(PHOSPHONIC ACID), 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, ACETIC ACID, ...
Authors:Amzel, L.M, Huang, C.H, Gabelli, S.B, Oldfield, E.
Deposit date:2009-07-17
Release date:2010-02-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Binding of nitrogen-containing bisphosphonates (N-BPs) to the Trypanosoma cruzi farnesyl diphosphate synthase homodimer.
Proteins, 78, 2010
3IBA
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BU of 3iba by Molmil
Crystal structure of the complex of Trypanosoma cruzi farnesyl diphosphate synthase with zoledronate, IPP and Mg2+
Descriptor: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Farnesyl pyrophosphate synthase, MAGNESIUM ION, ...
Authors:Amzel, L.M, Huang, C.H, Gabelli, S.B, Oldfield, E.
Deposit date:2009-07-15
Release date:2010-02-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Binding of nitrogen-containing bisphosphonates (N-BPs) to the Trypanosoma cruzi farnesyl diphosphate synthase homodimer.
Proteins, 78, 2010
3ID8
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BU of 3id8 by Molmil
Ternary complex of human pancreatic glucokinase crystallized with activator, glucose and AMP-PNP
Descriptor: 2-AMINO-4-FLUORO-5-[(1-METHYL-1H-IMIDAZOL-2-YL)SULFANYL]-N-(1,3-THIAZOL-2-YL)BENZAMIDE, Glucokinase, MAGNESIUM ION, ...
Authors:Petit, P, Gluais, L, Lagarde, A, Boutin, J.A, Ferry, G, Vuillard, L.
Deposit date:2009-07-20
Release date:2010-07-28
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The active conformation of human glucokinase is not altered by allosteric activators
Acta Crystallogr.,Sect.D, 67, 2011
4EL0
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BU of 4el0 by Molmil
Crystal structure of GPb in complex with DK16
Descriptor: 3-(beta-D-glucopyranosyl)-6-propylfuro[2,3-d]pyrimidin-2(3H)-one, Glycogen phosphorylase, muscle form
Authors:Kantsadi, A.L, Skamnaki, V.T, Leonidas, D.D.
Deposit date:2012-04-10
Release date:2012-07-25
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The binding of C5-alkynyl and alkylfurano[2,3-d]pyrimidine glucopyranonucleosides to glycogen phosphorylase b: Synthesis, biochemical and biological assessment.
Eur.J.Med.Chem., 54, 2012
1JJ2
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BU of 1jj2 by Molmil
Fully Refined Crystal Structure of the Haloarcula marismortui Large Ribosomal Subunit at 2.4 Angstrom Resolution
Descriptor: 23S RRNA, 5S RRNA, CADMIUM ION, ...
Authors:Klein, D.J, Schmeing, T.M, Moore, P.B, Steitz, T.A.
Deposit date:2001-07-03
Release date:2001-08-01
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The kink-turn: a new RNA secondary structure motif.
EMBO J., 20, 2001
1QPX
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BU of 1qpx by Molmil
CRYSTAL STRUCTURES OF SELF-CAPPING PAPD CHAPERONE HOMODIMERS
Descriptor: PAPD CHAPERONE
Authors:Hung, D.L, Pinkner, J.S, Knight, S.D, Hultgren, S.J.
Deposit date:1999-05-31
Release date:1999-07-07
Last modified:2022-12-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis of chaperone self-capping in P pilus biogenesis.
Proc.Natl.Acad.Sci.USA, 96, 1999
3ICN
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BU of 3icn by Molmil
Trypanosoma cruzi farnesyl diphosphate synthase homodimer in complex with isopentenyl pyrophosphate and 3-Fluoro-1-(2-hydroxy-2,2-bis-phosphono-ethyl)-pyridinium
Descriptor: 3-FLUORO-1-(2-HYDROXY-2,2-DIPHOSPHONOETHYL)PYRIDINIUM, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Farnesyl pyrophosphate synthase, ...
Authors:Amzel, L.M, Huang, C.H, Gabelli, S.B, Oldfield, E.
Deposit date:2009-07-17
Release date:2010-02-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Binding of nitrogen-containing bisphosphonates (N-BPs) to the Trypanosoma cruzi farnesyl diphosphate synthase homodimer.
Proteins, 78, 2010
1NOJ
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BU of 1noj by Molmil
COMPLEX OF GLYCOGEN PHOSPHORYLASE WITH A TRANSITION STATE ANALOGUE NOJIRIMYCIN TETRAZOLE AND PHOSPHATE IN THE T STATE
Descriptor: GLYCOGEN PHOSPHORYLASE, NOJIRIMYCINE TETRAZOLE, PHOSPHATE ION, ...
Authors:Johnson, L.N, Mitchell, E.P.
Deposit date:1996-03-12
Release date:1996-07-11
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Ternary complex crystal structures of glycogen phosphorylase with the transition state analogue nojirimycin tetrazole and phosphate in the T and R states.
Biochemistry, 35, 1996
1NOK
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BU of 1nok by Molmil
COMPLEX OF GLYCOGEN PHOSPHORYLASE WITH A TRANSITION STATE ANALOGUE NOJIRIMYCIN TETRAZOLE AND PHOSPHATE IN THE T STATE
Descriptor: GLYCOGEN PHOSPHORYLASE, NOJIRIMYCINE TETRAZOLE, PYRIDOXAL-5'-PHOSPHATE
Authors:Johnson, L.N, Mitchell, E.P.
Deposit date:1996-03-12
Release date:1996-07-11
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Ternary complex crystal structures of glycogen phosphorylase with the transition state analogue nojirimycin tetrazole and phosphate in the T and R states.
Biochemistry, 35, 1996
1HIB
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BU of 1hib by Molmil
THE STRUCTURE OF AN INTERLEUKIN-1 BETA MUTANT WITH REDUCED BIOACTIVITY SHOWS MULTIPLE SUBTLE CHANGES IN CONFORMATION THAT AFFECT PROTEIN-PROTEIN RECOGNITION
Descriptor: INTERLEUKIN-1 BETA
Authors:Camacho, N.P, Smith, D.R, Goldman, A, Schneider, B, Green, D, Young, P.R, Berman, H.M.
Deposit date:1993-03-29
Release date:1994-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of an interleukin-1 beta mutant with reduced bioactivity shows multiple subtle changes in conformation that affect protein-protein recognition.
Biochemistry, 32, 1993
1Z6P
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BU of 1z6p by Molmil
Glycogen phosphorylase AMP site inhibitor complex
Descriptor: 4-{2-[(3-NITROBENZOYL)AMINO]PHENOXY}PHTHALIC ACID, Glycogen phosphorylase, muscle form
Authors:Kristiansen, M, Andersen, B, Iversen, L.F, Westergaard, N.
Deposit date:2005-03-23
Release date:2005-04-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Identification, synthesis and chracterization of new glycogen phosphorylase inhibitors binding to the allosteric AMP site
J.Med.Chem., 47, 2004
2SKC
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BU of 2skc by Molmil
PYRIDOXAL PHOSPHORYLASE B IN COMPLEX WITH FLUOROPHOSPHATE, GLUCOSE AND INOSINE-5'-MONOPHOSPHATE
Descriptor: FLUORO-PHOSPHITE ION, INOSINIC ACID, PYRIDOXAL PHOSPHORYLASE B, ...
Authors:Oikonomakos, N.G, Zographos, S.E, Tsitsanou, K.E, Johnson, L.N, Acharya, K.R.
Deposit date:1998-12-11
Release date:1998-12-16
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Activator anion binding site in pyridoxal phosphorylase b: the binding of phosphite, phosphate, and fluorophosphate in the crystal.
Protein Sci., 5, 1996
1PDK
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BU of 1pdk by Molmil
PAPD-PAPK CHAPERONE-PILUS SUBUNIT COMPLEX FROM E.COLI P PILUS
Descriptor: PROTEIN (CHAPERONE PROTEIN PAPD), PROTEIN (PROTEIN PAPK)
Authors:Fuetterer, K, Sauer, F.G, Hultgren, S.J, Waksman, G.
Deposit date:1999-03-29
Release date:1999-08-17
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis of chaperone function and pilus biogenesis.
Science, 285, 1999
2SKD
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BU of 2skd by Molmil
PYRIDOXAL PHOSPHORYLASE B IN COMPLEX WITH PHOSPHATE, GLUCOSE AND INOSINE-5'-MONOPHOSPHATE
Descriptor: INOSINIC ACID, PHOSPHATE ION, PYRIDOXAL PHOSPHORYLASE B, ...
Authors:Oikonomakos, N.G, Zographos, S.E, Tsitsanou, K.E, Johnson, L.N, Acharya, K.R.
Deposit date:1998-12-11
Release date:1998-12-16
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Activator anion binding site in pyridoxal phosphorylase b: the binding of phosphite, phosphate, and fluorophosphate in the crystal.
Protein Sci., 5, 1996
1FA9
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BU of 1fa9 by Molmil
HUMAN LIVER GLYCOGEN PHOSPHORYLASE A COMPLEXED WITH AMP
Descriptor: ADENOSINE MONOPHOSPHATE, GLYCOGEN PHOSPHORYLASE, LIVER FORM, ...
Authors:Rath, V.L, Ammirati, M, LeMotte, P.K, Fennell, K.F, Mansour, M.N, Danley, D.E, Hynes, T.R, Schulte, G.K, Wasilko, D.J, Pandit, J.
Deposit date:2000-07-12
Release date:2000-08-25
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Activation of human liver glycogen phosphorylase by alteration of the secondary structure and packing of the catalytic core.
Mol.Cell, 6, 2000
1FC0
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BU of 1fc0 by Molmil
HUMAN LIVER GLYCOGEN PHOSPHORYLASE COMPLEXED WITH N-ACETYL-BETA-D-GLUCOPYRANOSYLAMINE
Descriptor: GLYCOGEN PHOSPHORYLASE, LIVER FORM, N-acetyl-beta-D-glucopyranosylamine, ...
Authors:Rath, V.L, Ammirati, M, LeMotte, P.K, Fennell, K.F, Mansour, M.M, Danley, D.E, Hynes, T.R, Schulte, G.K, Wasilko, D.J, Pandit, J.
Deposit date:2000-07-17
Release date:2000-08-25
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Activation of human liver glycogen phosphorylase by alteration of the secondary structure and packing of the catalytic core.
Mol.Cell, 6, 2000
2QN1
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BU of 2qn1 by Molmil
Glycogen Phosphorylase b in complex with asiatic acid
Descriptor: Glycogen phosphorylase, muscle form, asiatic acid
Authors:Zographos, S.E, Leonidas, D.D, Alexacou, K.-M, Hayes, J, Oikonomakos, N.G.
Deposit date:2007-07-17
Release date:2008-06-03
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.401 Å)
Cite:Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies
J.Med.Chem., 51, 2008
4V9F
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BU of 4v9f by Molmil
The re-refined crystal structure of the Haloarcula marismortui large ribosomal subunit at 2.4 Angstrom resolution: more complete structure of the L7/L12 and L1 stalk, L5 and LX proteins
Descriptor: 23S Ribosomal RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ...
Authors:Gabdulkhakov, A.
Deposit date:2012-11-02
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.404 Å)
Cite:Revisiting the Haloarcula marismortui 50S ribosomal subunit model.
Acta Crystallogr.,Sect.D, 69, 2013
4P0W
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BU of 4p0w by Molmil
Human farnesyl diphosphate synthase in complex with Arenarone and zoledronate
Descriptor: 2-{[(1S,2R,4aS,8aR)-1,2,4a-trimethyl-5-methylidenedecahydronaphthalen-1-yl]methyl}cyclohexa-2,5-diene-1,4-dione, Farnesyl pyrophosphate synthase, MAGNESIUM ION, ...
Authors:Liu, Y.L, Oldfield, E.
Deposit date:2014-02-23
Release date:2014-07-02
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.406 Å)
Cite:Taxodione and arenarone inhibit farnesyl diphosphate synthase by binding to the isopentenyl diphosphate site.
Proc.Natl.Acad.Sci.USA, 111, 2014
3P9W
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BU of 3p9w by Molmil
Crystal structure of an engineered human autonomous VH Domain in complex with VEGF
Descriptor: Vascular endothelial growth factor A, human VEGF
Authors:Ma, X, Wiesmann, C.
Deposit date:2010-10-18
Release date:2012-04-18
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Design of Synthetic Autonomous VH Domain Libraries and Structural Analysis of a VH Domain Bound to Vascular Endothelial Growth Factor.
J.Mol.Biol., 425, 2013
6V0K
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BU of 6v0k by Molmil
Crystal structure of Penicillium verruculosum copalyl diphosphate synthase (PvCPS) alpha prenyltransferase domain
Descriptor: GLYCEROL, Terpene synthase
Authors:Christianson, D.W, Ronnebaum, T.A.
Deposit date:2019-11-18
Release date:2020-01-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Higher-order oligomerization of a chimeric alpha beta gamma bifunctional diterpene synthase with prenyltransferase and class II cyclase activities is concentration-dependent.
J.Struct.Biol., 210, 2020
7Y7E
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BU of 7y7e by Molmil
Structure of the Bacterial Ribosome with human tRNA Asp(ManQ34) and mRNA(GAU)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T.
Deposit date:2022-06-22
Release date:2023-10-25
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (2.41 Å)
Cite:Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Cell, 186, 2023
3KRP
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BU of 3krp by Molmil
Mint heterotetrameric geranyl pyrophosphate synthase in complex with magnesium and GPP
Descriptor: 1,2-ETHANEDIOL, GERANYL DIPHOSPHATE, Geranyl diphosphate synthase large subunit, ...
Authors:Chang, T.-H, Hsieh, F.-L, Ko, T.-P, Wang, A.H.-J.
Deposit date:2009-11-19
Release date:2010-02-23
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Structure of a heterotetrameric geranyl pyrophosphate synthase from mint (Mentha piperita) reveals intersubunit regulation
Plant Cell, 22, 2010
8JDL
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BU of 8jdl by Molmil
Structure of the Human cytoplasmic Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU) (non-rotated state)
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T.
Deposit date:2023-05-14
Release date:2023-12-06
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (2.42 Å)
Cite:Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Cell, 186, 2023
1RQI
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BU of 1rqi by Molmil
Active Conformation of Farnesyl Pyrophosphate Synthase Bound to Isopentyl Pyrophosphate and Dimethylallyl S-Thiolodiphosphate
Descriptor: DIMETHYLALLYL S-THIOLODIPHOSPHATE, DIPHOSPHATE, Geranyltranstransferase, ...
Authors:Hosfield, D.J, Zhang, Y, Dougan, D.R, Brooun, A, Tari, L.W, Swanson, R.V, Finn, J.
Deposit date:2003-12-05
Release date:2004-03-02
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Structural basis for bisphosphonate-mediated inhibition of isoprenoid biosynthesis
J.Biol.Chem., 279, 2004

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数据于2024-09-11公开中

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