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8GA5	CLC-ec1 L25C/A450C/C85A at pH 4.5 100mM Cl Intermediate Descriptor: CHLORIDE ION, H(+)/Cl(-) exchange transporter ClcA Authors: Fortea, E, Lee, S, Argyos, Y, Chadda, R, Ciftci, D, Huysmans, G, Robertson, J.L, Boudker, O, Accardi, A. Deposit date: 2023-02-22 Release date: 2024-02-07 Last modified: 2024-10-16 Method: ELECTRON MICROSCOPY (2.6 Å) Cite: Structural basis of pH-dependent activation in a CLC transporter. Nat.Struct.Mol.Biol., 31, 2024
7CVT	Crystal structure of the C85A/L194A/H234C mutant CLC-ec1 with Fab fragment Descriptor: CHLORIDE ION, H(+)/Cl(-) exchange transporter ClcA, antibody Fab fragment heavy chain, ... Authors: Park, K, Mersch, K, Robertson, J, Lim, H.-H. Deposit date: 2020-08-27 Release date: 2021-09-01 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Altering CLC stoichiometry by reducing non-polar side-chains at the dimerization interface. J.Mol.Biol., 433, 2021
7CVS	Crystal structure of the C85A/L194A mutant CLC-ec1 with Fab fragment Descriptor: CHLORIDE ION, H(+)/Cl(-) exchange transporter ClcA, antibody Fab fragment heavy chain, ... Authors: Park, K, Mersch, K, Robertson, J, Lim, H.-H. Deposit date: 2020-08-27 Release date: 2021-09-01 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (3.01 Å) Cite: Altering CLC stoichiometry by reducing non-polar side-chains at the dimerization interface. J.Mol.Biol., 433, 2021
6COZ	Human CLC-1 chloride ion channel, C-terminal cytosolic domain Descriptor: Chloride channel protein 1 Authors: Park, E, MacKinnon, R. Deposit date: 2018-03-13 Release date: 2018-06-13 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (3.36 Å) Cite: Structure of the CLC-1 chloride channel fromHomo sapiens. Elife, 7, 2018
2FED	Structure of the E203Q mutant of the Cl-/H+ exchanger CLC-ec1 from E.Coli Descriptor: Fab fragment, heavy chain, light chain, ... Authors: Accardi, A, Walden, M.P, Nguitragool, W, Jayaram, H, Williams, C, Miller, C. Deposit date: 2005-12-15 Release date: 2006-01-03 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (3.317 Å) Cite: Separate ion pathways in a Cl-/H+ exchanger J.Gen.Physiol., 126, 2005
2FEE	Structure of the Cl-/H+ exchanger CLC-ec1 from E.Coli in NaBr Descriptor: Fab fragment, heavy chain, light chain, ... Authors: Accardi, A, Walden, M.P, Nguitragool, W, Jayaram, H, Williams, C, Miller, C. Deposit date: 2005-12-15 Release date: 2006-01-03 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Separate ion pathways in a Cl-/H+ exchanger J.Gen.Physiol., 126, 2005
2EZ0	Crystal structure of the S107A/E148Q/Y445A mutant of EcClC, in complex with a FaB fragment Descriptor: BROMIDE ION, Fab Fragment (Heavy Chain), Fab Fragment (Light Chain), ... Authors: Lobet, S, Dutzler, R. Deposit date: 2005-11-10 Release date: 2006-01-24 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (3.54 Å) Cite: Ion-binding properties of the ClC chloride selectivity filter. Embo J., 25, 2006
2FEC	Structure of the E203Q mutant of the Cl-/H+ exchanger CLC-ec1 from E.Coli Descriptor: Fab fragment, heavy chain, light chain, ... Authors: Accardi, A, Walden, M.P, Nguitragool, W, Jayaram, H, Williams, C, Miller, C. Deposit date: 2005-12-15 Release date: 2006-01-03 Last modified: 2021-10-20 Method: X-RAY DIFFRACTION (3.967 Å) Cite: Separate ion pathways in a Cl-/H+ exchanger J.Gen.Physiol., 126, 2005
2EXW	Crystal structure of a EcClC-Fab complex in the absence of bound ions Descriptor: Fab Fragment (Heavy Chain), Fab Fragment (Light Chain), H(+)/Cl(-) exchange transporter clcA Authors: Lobet, S, Dutzler, R. Deposit date: 2005-11-09 Release date: 2006-01-24 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Ion-binding properties of the ClC chloride selectivity filter. Embo J., 25, 2006
4KJQ	Structure of the CLC-ec1 deltaNC construct in 100mM fluoride Descriptor: FLUORIDE ION, Fab, heavy chain, ... Authors: Lim, H.-H, Miller, C. Deposit date: 2013-05-03 Release date: 2013-08-21 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.875 Å) Cite: Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter. Nat.Chem.Biol., 9, 2013
4KK9	Structure of the E148A mutant of CLC-ec1 deltaNC construct in 100mM fluoride and 2mM Bromide Descriptor: Fab, heavy chain, light chain, ... Authors: Lim, H.-H, Miller, C. Deposit date: 2013-05-05 Release date: 2013-08-21 Last modified: 2013-11-13 Method: X-RAY DIFFRACTION (2.997 Å) Cite: Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter. Nat.Chem.Biol., 9, 2013
4KJP	Structure of the CLC-ec1 deltaNC construct in the absence of halide Descriptor: H(+)/Cl(-) exchange transporter ClcA, heavy chain of Fab fragment, light chain of Fab fragment Authors: Lim, H.-H, Miller, C. Deposit date: 2013-05-03 Release date: 2013-08-21 Last modified: 2018-01-24 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter. Nat.Chem.Biol., 9, 2013
4KK6	Structure of CLC-ec1 deltaNC construct in 20mM Bromide Descriptor: BROMIDE ION, Fab, heavy chain, ... Authors: Lim, H.-H, Miller, C. Deposit date: 2013-05-05 Release date: 2013-08-21 Last modified: 2013-11-13 Method: X-RAY DIFFRACTION (3.183 Å) Cite: Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter. Nat.Chem.Biol., 9, 2013
4KKA	Structure of the E148A mutant of CLC-ec1 deltaNC construct in 100mM fluoride and 20mM Bromide Descriptor: Fab, heavy chain, light chain, ... Authors: Lim, H.-H, Miller, C. Deposit date: 2013-05-05 Release date: 2013-08-21 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (3 Å) Cite: Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter. Nat.Chem.Biol., 9, 2013
4KJW	Structure of the CLC-ec1 deltaNC construct in 100mM fluoride and 20mM bromide Descriptor: Fab, heavy chain, light chain, ... Authors: Lim, H.-H, Miller, C. Deposit date: 2013-05-03 Release date: 2013-08-21 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (3.03 Å) Cite: Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter. Nat.Chem.Biol., 9, 2013
4KKC	Structure of the E148A mutant of CLC-ec1 deltaNC construct in 20mM Bromide Descriptor: Fab, heavy chain, light chain, ... Authors: Lim, H.-H, Miller, C. Deposit date: 2013-05-05 Release date: 2013-08-21 Last modified: 2013-12-04 Method: X-RAY DIFFRACTION (3.18 Å) Cite: Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter. Nat.Chem.Biol., 9, 2013
4MQX	CLC-ec1 Fab Complex Cysless A399C-A432C mutant Descriptor: CHLORIDE ION, ERIC, H(+)/Cl(-) exchange transporter ClcA, ... Authors: Basilio, D, Noack, K, Picollo, A, Accardi, A. Deposit date: 2013-09-16 Release date: 2014-04-16 Last modified: 2014-05-28 Method: X-RAY DIFFRACTION (3.516 Å) Cite: Conformational changes required for H(+)/Cl(-) exchange mediated by a CLC transporter. Nat.Struct.Mol.Biol., 21, 2014
3EJZ	Structure of E203V mutant E.coli Cl-/H+ exchanger, CLC-ec1 Descriptor: BROMIDE ION, Fab fragment, Heavy chain, ... Authors: Lim, H.-H, Miller, C. Deposit date: 2008-09-18 Release date: 2009-02-17 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Intracellular proton-transfer mutants in a CLC Cl-/H+ exchanger. J.Gen.Physiol., 133, 2009
1OTS	Structure of the Escherichia coli ClC Chloride channel and Fab Complex Descriptor: CHLORIDE ION, Fab fragment (heavy chain), Fab fragment (light chain), ... Authors: Dutzler, R, Campbell, E.B, MacKinnon, R. Deposit date: 2003-03-22 Release date: 2003-04-15 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.51 Å) Cite: Gating the Selectivity Filter in ClC Chloride Channels Science, 300, 2003
1OTU	Structure of the Escherichia coli ClC Chloride channel E148Q mutant and Fab Complex Descriptor: CHLORIDE ION, Fab fragment (Heavy chain), Fab fragment (Light chain), ... Authors: Dutzler, R, Campbell, E.B, MacKinnon, R. Deposit date: 2003-03-23 Release date: 2003-04-15 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Gating the Selectivity Filter in ClC Chloride Channels Science, 300, 2003
1OTT	Structure of the Escherichia coli ClC Chloride channel E148A mutant and Fab Complex Descriptor: CHLORIDE ION, Fab fragment (Heavy chain), Fab fragment (Light chain), ... Authors: Dutzler, R, Campbell, E.B, MacKinnon, R. Deposit date: 2003-03-23 Release date: 2003-04-15 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (3 Å) Cite: Gating the Selectivity Filter in ClC Chloride Channels Science, 300, 2003
2HTL	Structure of the Escherichia coli ClC chloride channel Y445F mutant and Fab complex Descriptor: BROMIDE ION, Fab fragment, Heavy chain, ... Authors: Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R. Deposit date: 2006-07-26 Release date: 2006-09-19 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (3.4 Å) Cite: Synergism Between Halide Binding and Proton Transport in a CLC-type Exchanger. J.Mol.Biol., 362, 2006
2HTK	Structure of the Escherichia coli ClC chloride channel Y445A mutant and Fab complex Descriptor: BROMIDE ION, Fab fragment, Heavy chain, ... Authors: Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R. Deposit date: 2006-07-26 Release date: 2006-09-19 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (3.41 Å) Cite: Synergism between halide binding and proton transport in a CLC-type exchanger J.Mol.Biol., 362, 2006
2HT2	Structure of the Escherichia coli ClC chloride channel Y445H mutant and Fab complex Descriptor: BROMIDE ION, Fab fragment, heavy chain, ... Authors: Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R. Deposit date: 2006-07-25 Release date: 2006-09-19 Last modified: 2021-10-20 Method: X-RAY DIFFRACTION (3.32 Å) Cite: Synergism Between Halide Binding and Proton Transport in a CLC-type Exchanger. J.Mol.Biol., 362, 2006
2HLF	Structure of the Escherichis coli ClC chloride channel Y445E mutant and Fab complex Descriptor: BROMIDE ION, Fab Fragment, Heavy chain, ... Authors: Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R. Deposit date: 2006-07-07 Release date: 2006-09-19 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Synergism Between Halide Binding and Proton Transport in a CLC-type Exchanger J.Mol.Biol., 362, 2006

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