7CVT
Crystal structure of the C85A/L194A/H234C mutant CLC-ec1 with Fab fragment
Summary for 7CVT
Entry DOI | 10.2210/pdb7cvt/pdb |
Descriptor | H(+)/Cl(-) exchange transporter ClcA, antibody Fab fragment heavy chain, antibody Fab fragment light chain, ... (4 entities in total) |
Functional Keywords | clc, chloride, dimer interface, transport protein |
Biological source | Escherichia coli MS 198-1 More |
Total number of polymer chains | 6 |
Total formula weight | 194491.82 |
Authors | Park, K.,Mersch, K.,Robertson, J.,Lim, H.-H. (deposition date: 2020-08-27, release date: 2021-09-01, Last modification date: 2023-11-29) |
Primary citation | Mersch, K.,Ozturk, T.N.,Park, K.,Lim, H.H.,Robertson, J.L. Altering CLC stoichiometry by reducing non-polar side-chains at the dimerization interface. J.Mol.Biol., 433:166886-166886, 2021 Cited by PubMed: 33617898DOI: 10.1016/j.jmb.2021.166886 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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