4UEZ
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![BU of 4uez by Molmil](/molmil-images/mine/4uez) | Crystal structure of the human CARBOXYPEPTIDASE A1 in complex with the PHOSPHINIC INHIBITOR Acetyl-Leu-Phe-Y(PO2CH2)-Phe-OH | Descriptor: | (2S)-3-[(R)-{(1R)-1-[(N-acetyl-L-leucyl)amino]-2-phenylethyl}(hydroxy)phosphoryl]-2-benzylpropanoic acid, HUMAN CARBOXYPEPTIDASE A1, ZINC ION | Authors: | Gallego, P, Covaleda, G, Costenaro, L, Devel, L, Dive, V, Aviles, F.X, Reverter, D. | Deposit date: | 2014-12-22 | Release date: | 2016-01-20 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Crystal Structure of the Human Carboxypeptidase A1 in Complex with Phosphinic Inhibitors To be Published
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4UEE
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![BU of 4uee by Molmil](/molmil-images/mine/4uee) | Crystal structure of the human CARBOXYPEPTIDASE A1 in complex with the PHOSPHINIC INHIBITOR Acetyl-Leu-Ala-Y(PO2CH2)-homoPhe-OH | Descriptor: | (2S)-2-{[(R)-{(1R)-1-[(N-acetyl-L-leucyl)amino]ethyl}(hydroxy)phosphoryl]methyl}-4-phenylbutanoic acid, CARBOXYPEPTIDASE A1, ZINC ION | Authors: | Gallego, P, Covaleda, G, Costenaro, L, Devel, L, Dive, V, Aviles, F.X, Reverter, D. | Deposit date: | 2014-12-17 | Release date: | 2016-01-20 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | Crystal Structure of the Human Carboxypeptidase A1 in Complex with Phosphinic Inhibitors To be Published
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4P10
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![BU of 4p10 by Molmil](/molmil-images/mine/4p10) | pro-carboxypeptidase U In Complex With 5-(3-aminopropyl)-1-propyl-6,7-dihydro-4H-benzimidazole-5-carboxylic acid | Descriptor: | (5R)-5-(3-aminopropyl)-1-propyl-4,5,6,7-tetrahydro-1H-benzimidazole-5-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Carboxypeptidase B2, ... | Authors: | Hallberg, K, Sjogren, T. | Deposit date: | 2014-02-21 | Release date: | 2014-08-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Design and synthesis of conformationally restricted inhibitors of active thrombin activatable fibrinolysis inhibitor (TAFIa). Bioorg.Med.Chem., 22, 2014
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4OKO
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![BU of 4oko by Molmil](/molmil-images/mine/4oko) | Crystal structure of Francisella tularensis REP34 (Rapid Encystment Phenotype Protein 34 KDa) | Descriptor: | ACETATE ION, Rapid Encystment Phenotype Protein 34 KDa, ZINC ION | Authors: | Feld, G.K, Segelke, B.W, Corzett, M.H, Hunter, M.S, Frank, M, Rasley, A. | Deposit date: | 2014-01-22 | Release date: | 2014-09-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.053 Å) | Cite: | Structure and Function of REP34 Implicates Carboxypeptidase Activity in Francisella tularensis Host Cell Invasion. J.Biol.Chem., 289, 2014
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4IK2
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![BU of 4ik2 by Molmil](/molmil-images/mine/4ik2) | G215S, A251G, T257A, D260G, T262D mutant of carboxypeptidase T from Thermoactinomyces vulgaris with N-BOC-L-Leu | Descriptor: | CALCIUM ION, Carboxypeptidase T, N-(tert-butoxycarbonyl)-L-leucine, ... | Authors: | Timofeev, V.I, Kuznetsov, S.A, Akparov, V.K, Kuranova, I.P. | Deposit date: | 2012-12-25 | Release date: | 2013-12-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | G215S, A251G, T257A, D260G, T262D mutant of carboxypeptidase T from Thermoactinomyces vulgaris with N-BOC-L-Leu To be published
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4IHM
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![BU of 4ihm by Molmil](/molmil-images/mine/4ihm) | G215S, A251G, T257A, D260G, T262D mutant of carboxypeptidase T from Thermoactinomyces vulgaris | Descriptor: | CALCIUM ION, Carboxypeptidase T, GLYCEROL, ... | Authors: | Timofeev, V.I, Kuznetsov, S.A, Akparov, V.K, Kuranova, I.P. | Deposit date: | 2012-12-19 | Release date: | 2013-12-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.29 Å) | Cite: | G215S, A251G, T257A, D260G, T262D mutant of carboxypeptidase T from Thermoactinomyces vulgaris To be published
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4IAV
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![BU of 4iav by Molmil](/molmil-images/mine/4iav) | G215S, A251G, T257A, D260G, T262D mutant of carboxypeptidase T from Thermoactinomyces vulgaris with N-Sulfamoyl-L-phenylalanine | Descriptor: | CALCIUM ION, Carboxypeptidase T, GLYCEROL, ... | Authors: | Timofeev, V.I, Kuznetsov, S.A, Akparov, V.K, Kuranova, I.P. | Deposit date: | 2012-12-07 | Release date: | 2013-12-11 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | G215S, A251G, T257A, D260G, T262D mutant of carboxypeptidase T from Thermoactinomyces vulgaris with N-Sulfamoyl-L-phenylalanine TO BE PUBLISHED
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4GM5
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![BU of 4gm5 by Molmil](/molmil-images/mine/4gm5) | Carboxypeptidase T with Sulphamoil Arginine | Descriptor: | CALCIUM ION, Carboxypeptidase T, GLYCEROL, ... | Authors: | Kuznetsov, S.A, Timofeev, V.I, Akparov, V.K, Kuranova, I.P. | Deposit date: | 2012-08-15 | Release date: | 2013-08-21 | Method: | X-RAY DIFFRACTION (1.39 Å) | Cite: | Carboxypeptidase T with Sulphamoil Arginine To be Published
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4F8Z
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![BU of 4f8z by Molmil](/molmil-images/mine/4f8z) | Carboxypeptidase T with Boc-Leu | Descriptor: | CALCIUM ION, Carboxypeptidase T, GLYCEROL, ... | Authors: | Timofeev, V.I, Kuznetsov, S.A, Akparov, V.K, Kuranova, I.P. | Deposit date: | 2012-05-18 | Release date: | 2013-05-22 | Last modified: | 2015-09-30 | Method: | X-RAY DIFFRACTION (1.38 Å) | Cite: | Three-dimensional structure of carboxypeptidase T from Thermoactinomyces vulgaris in complex with N-BOC-L-leucine. Biochemistry Mosc., 78, 2013
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4DUK
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![BU of 4duk by Molmil](/molmil-images/mine/4duk) | Carboxypeptidase T with L-BENZYLSUCCINIC ACID | Descriptor: | CALCIUM ION, Carboxypeptidase T, GLYCEROL, ... | Authors: | Kuznetsov, S.A, Timofeev, V.I, Akparov, V.K, Kuranova, I.P. | Deposit date: | 2012-02-22 | Release date: | 2013-02-27 | Last modified: | 2015-09-30 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | Structural insights into the broad substrate specificity of carboxypeptidase T from Thermoactinomyces vulgaris. Febs J., 282, 2015
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4DJL
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![BU of 4djl by Molmil](/molmil-images/mine/4djl) | Carboxypeptidase T with N-sulfamoyl-L-phenylalanine | Descriptor: | CALCIUM ION, Carboxypeptidase T, GLYCEROL, ... | Authors: | Kuznetsov, S.A, Timofeev, V.I, Akparov, V.K, Kuranova, I.P. | Deposit date: | 2012-02-02 | Release date: | 2013-02-06 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Carboxypeptidase T with N-sulfamoyl-L-phenylalanine TO BE PUBLISHED
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4CPA
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![BU of 4cpa by Molmil](/molmil-images/mine/4cpa) | |
4BD9
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![BU of 4bd9 by Molmil](/molmil-images/mine/4bd9) | Structure of the complex between SmCI and human carboxypeptidase A4 | Descriptor: | CARBOXYPEPTIDASE A4, CARBOXYPEPTIDASE INHIBITOR SMCI, ZINC ION | Authors: | Alonso-del-Ribero, M, Reytor, M.L, Trejo, S.A, Chavez, M.A, Aviles, F.X, Reverter, D. | Deposit date: | 2012-10-05 | Release date: | 2013-07-17 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | A Noncanonical Mechanism of Carboxypeptidase Inhibition Revealed by the Crystal Structure of the Tri-Kunitz Smci in Complex with Human Cpa4. Structure, 21, 2013
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4B6Z
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![BU of 4b6z by Molmil](/molmil-images/mine/4b6z) | Crystal structure of metallo-carboxypeptidase from Burkholderia cenocepacia | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ... | Authors: | Rimsa, V, Eadsforth, T.C, Joosten, R.P, Hunter, W.N. | Deposit date: | 2012-08-16 | Release date: | 2013-03-27 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | High-Resolution Structure of the M14-Type Cytosolic Carboxypeptidase from Burkholderia Cenocepacia Refined Exploiting Pdb_Redo Strategies. Acta Crystallogr.,Sect.D, 70, 2014
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4A94
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![BU of 4a94 by Molmil](/molmil-images/mine/4a94) | Structure of the carboxypeptidase inhibitor from Nerita versicolor in complex with human CPA4 | Descriptor: | CARBOXYPEPTIDASE A4, CARBOXYPEPTIDASE INHIBITOR, NITRATE ION, ... | Authors: | Covaleda, G, Alonso, M, Chavez, M.A, Aviles, F.X, Reverter, D. | Deposit date: | 2011-11-23 | Release date: | 2011-12-28 | Last modified: | 2012-03-28 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal Structure of a Novel Metallo-Carboxypeptidase Inhibitor from the Marine Mollusk Nerita Versicolor in Complex with Human Carboxypeptidase A4. J.Biol.Chem., 287, 2012
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4A39
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![BU of 4a39 by Molmil](/molmil-images/mine/4a39) | Metallo-carboxypeptidase from Pseudomonas Aeruginosa in complex with (2-guanidinoethylmercapto)succinic acid | Descriptor: | (2-GUANIDINOETHYLMERCAPTO)SUCCINIC ACID, METALLO-CARBOXYPEPTIDASE, ZINC ION | Authors: | Otero, A, Rodriguez de la Vega, M, Tanco, S.M, Lorenzo, J, Aviles, F.X, Reverter, D. | Deposit date: | 2011-09-30 | Release date: | 2012-05-09 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The Novel Structure of a Cytosolic M14 Metallocarboxypeptidase (Ccp) from Pseudomonas Aeruginosa: A Model for Mammalian Ccps. Faseb J., 26, 2012
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4A38
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![BU of 4a38 by Molmil](/molmil-images/mine/4a38) | METALLO-CARBOXYPEPTIDASE FROM PSEUDOMONAS AUREGINOSA IN COMPLEX WITH L-BENZYLSUCCINIC ACID | Descriptor: | L-BENZYLSUCCINIC ACID, METALLO-CARBOXYPEPTIDASE, ZINC ION | Authors: | Otero, A, Rodriguez de la Vega, M, Tanco, S.M, Lorenzo, J, Aviles, F.X, Reverter, D. | Deposit date: | 2011-09-30 | Release date: | 2012-05-09 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The Novel Structure of a Cytosolic M14 Metallocarboxypeptidase (Ccp) from Pseudomonas Aeruginosa: A Model for Mammalian Ccps. Faseb J., 26, 2012
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4A37
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![BU of 4a37 by Molmil](/molmil-images/mine/4a37) | Metallo-carboxypeptidase from Pseudomonas Aeruginosa | Descriptor: | METALLO-CARBOXYPEPTIDASE, ZINC ION | Authors: | Otero, A, Rodriguez de la Vega, M, Tanco, S.M, Lorenzo, J, Aviles, F.X, Reverter, D. | Deposit date: | 2011-09-30 | Release date: | 2012-05-09 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The Novel Structure of a Cytosolic M14 Metallocarboxypeptidase (Ccp) from Pseudomonas Aeruginosa: A Model for Mammalian Ccps. Faseb J., 26, 2012
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3WC7
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![BU of 3wc7 by Molmil](/molmil-images/mine/3wc7) | Carboxypeptidase B in complex with EF6265 | Descriptor: | (2S)-7-amino-2-{[(R)-hydroxy{(1R)-2-methyl-1-[(3-phenylpropanoyl)amino]propyl}phosphoryl]methyl}heptanoic acid, Carboxypeptidase B, ZINC ION | Authors: | Yoshimoto, N, Itoh, T, Inaba, Y, Yamamoto, K. | Deposit date: | 2013-05-24 | Release date: | 2013-10-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural basis for inhibition of carboxypeptidase B by selenium-containing inhibitor: selenium coordinates to zinc in enzyme. J.Med.Chem., 56, 2013
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3WC6
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![BU of 3wc6 by Molmil](/molmil-images/mine/3wc6) | Carboxypeptidase B in complex with 2nd zinc | Descriptor: | ACETATE ION, Carboxypeptidase B, ZINC ION | Authors: | Yoshimoto, N, Itoh, T, Inaba, Y, Yamamoto, K. | Deposit date: | 2013-05-24 | Release date: | 2013-10-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural basis for inhibition of carboxypeptidase B by selenium-containing inhibitor: selenium coordinates to zinc in enzyme. J.Med.Chem., 56, 2013
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3WC5
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![BU of 3wc5 by Molmil](/molmil-images/mine/3wc5) | Carboxypeptidase B in complex with DD9 | Descriptor: | (2R)-7-amino-2-(selanylmethyl)heptanoic acid, CACODYLATE ION, Carboxypeptidase B, ... | Authors: | Yoshimoto, N, Itoh, T, Inaba, Y, Yamamoto, K. | Deposit date: | 2013-05-24 | Release date: | 2013-10-02 | Last modified: | 2022-08-24 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural basis for inhibition of carboxypeptidase B by selenium-containing inhibitor: selenium coordinates to zinc in enzyme. J.Med.Chem., 56, 2013
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3WAB
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![BU of 3wab by Molmil](/molmil-images/mine/3wab) | Carboxypeptidase B in complex with DD2 | Descriptor: | (2R)-7-amino-2-(sulfanylmethyl)heptanoic acid, CACODYLATE ION, Carboxypeptidase B, ... | Authors: | Yoshimoto, N, Itoh, T, Inaba, Y, Yamamoto, K. | Deposit date: | 2013-05-01 | Release date: | 2013-10-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.154 Å) | Cite: | Structural basis for inhibition of carboxypeptidase B by selenium-containing inhibitor: selenium coordinates to zinc in enzyme. J.Med.Chem., 56, 2013
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3V7Z
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![BU of 3v7z by Molmil](/molmil-images/mine/3v7z) | Carboxypeptidase T with GEMSA | Descriptor: | (2-GUANIDINOETHYLMERCAPTO)SUCCINIC ACID, CALCIUM ION, Carboxypeptidase T, ... | Authors: | Kuznetsov, S.A, Timofeev, V.I, Akparov, V.K, Kuranova, I.P. | Deposit date: | 2011-12-22 | Release date: | 2012-12-26 | Last modified: | 2015-09-30 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | Structural insights into the broad substrate specificity of carboxypeptidase T from Thermoactinomyces vulgaris. Febs J., 282, 2015
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3V38
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![BU of 3v38 by Molmil](/molmil-images/mine/3v38) | Carboxypeptidase T mutant L254N | Descriptor: | Carboxypeptidase T, GLYCEROL, SULFATE ION, ... | Authors: | Timofeev, V.I, Kuznetsov, S.A, Akparov, V.K, Kuranova, I.P. | Deposit date: | 2011-12-13 | Release date: | 2012-12-19 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Carboxypeptidase T mutant L254N TO BE PUBLISHED
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3QNV
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![BU of 3qnv by Molmil](/molmil-images/mine/3qnv) | Carboxypeptidase T | Descriptor: | Carboxypeptidase T, GLYCEROL, SULFATE ION, ... | Authors: | Timofeev, V.I, Akparov, V.K, Kuranova, I.P. | Deposit date: | 2011-02-09 | Release date: | 2012-02-15 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Three-dimensional structure of recombinant carboxypeptidase T from Thermoactinomyces vulgaris without calcium ions Crystallography Reports, 56, 2011
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