3SLC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3slc by Molmil](/molmil-images/mine/3slc) | |
2ANG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ang by Molmil](/molmil-images/mine/2ang) | CRYSTAL STRUCTURE OF HUMAN ANGIOGENIN OF THE MET(-1) FORM | Descriptor: | ANGIOGENIN, CITRIC ACID | Authors: | Leonidas, D.D, Allen, S.C, Acharya, K.R. | Deposit date: | 1998-11-12 | Release date: | 1999-04-02 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Refined crystal structures of native human angiogenin and two active site variants: implications for the unique functional properties of an enzyme involved in neovascularisation during tumour growth. J.Mol.Biol., 285, 1999
|
|
4D0N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4d0n by Molmil](/molmil-images/mine/4d0n) | AKAP13 (AKAP-Lbc) RhoGEF domain in complex with RhoA | Descriptor: | 1,2-ETHANEDIOL, A-KINASE ANCHOR PROTEIN 13, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Abdul Azeez, K.R, Shrestha, L, Krojer, T, Allerston, C, von Delft, F, Bountra, C, Arrowsmith, C, Edwards, A.M, Knapp, S, Klussmann, E, Elkins, J.M. | Deposit date: | 2014-04-29 | Release date: | 2014-05-21 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The Crystal Structure of the Rhoa : Akap-Lbc Dh-Ph Domain Complex. Biochem.J., 464, 2014
|
|
4E17
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4e17 by Molmil](/molmil-images/mine/4e17) | Alpha-E-catenin is an autoinhibited molecule that co-activates vinculin | Descriptor: | Catenin alpha-1, Vinculin | Authors: | Choi, H.-J, Pokutta, S, Cadwell, G.W, Bankston, L.A, Liddington, R.C, Weis, W.I. | Deposit date: | 2012-03-05 | Release date: | 2012-05-16 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.304 Å) | Cite: | Conformational plasticity of alpha-catenin revealed by binding interactions with vinculin To be Published
|
|
4BX2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4bx2 by Molmil](/molmil-images/mine/4bx2) | Crystal Structure of murine Chronophin (Pyridoxal Phosphate Phosphatase) in complex with Beryllium trifluoride | Descriptor: | BERYLLIUM TRIFLUORIDE ION, GLYCEROL, MAGNESIUM ION, ... | Authors: | Knobloch, G, Gohla, A, Schindelin, H. | Deposit date: | 2013-07-08 | Release date: | 2013-12-25 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.193 Å) | Cite: | Chronophin Dimerization is Required for Proper Positioning of its Substrate Specificity Loop. J.Biol.Chem., 289, 2014
|
|
4E18
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4e18 by Molmil](/molmil-images/mine/4e18) | Alpha-E-catenin is an autoinhibited molecule that co-activates vinculin | Descriptor: | Catenin alpha-1, Vinculin | Authors: | Choi, H.-J, Pokutta, S, Cadwell, G.W, Bankston, L.A, Liddington, R.C, Weis, W.I. | Deposit date: | 2012-03-05 | Release date: | 2012-05-16 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.403 Å) | Cite: | Conformational plasticity of alpha-catenin revealed by binding interactions with vinculin To be Published
|
|
4BX0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4bx0 by Molmil](/molmil-images/mine/4bx0) | Crystal Structure of a Monomeric Variant of murine Chronophin (Pyridoxal Phosphate phosphatase) | Descriptor: | GLYCEROL, MAGNESIUM ION, PYRIDOXAL PHOSPHATE PHOSPHATASE | Authors: | Kestler, C, Knobloch, G, Gohla, A, Schindelin, H. | Deposit date: | 2013-07-08 | Release date: | 2013-12-25 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Chronophin Dimerization is Required for Proper Positioning of its Substrate Specificity Loop J.Biol.Chem., 289, 2014
|
|
7WZC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7wzc by Molmil](/molmil-images/mine/7wzc) | An open conformation Form2 of switch II for RhoA GDP-bound state | Descriptor: | GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Jiang, H, Luo, C. | Deposit date: | 2022-02-17 | Release date: | 2023-02-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.79944921 Å) | Cite: | A RhoA structure with switch II flipped outward revealed the conformational dynamics of switch II region. J.Struct.Biol., 215, 2023
|
|
7WZA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7wza by Molmil](/molmil-images/mine/7wza) | An open conformation Form 1 of switch II for RhoA | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Transforming protein RhoA | Authors: | Jiang, H, Luo, C. | Deposit date: | 2022-02-17 | Release date: | 2023-02-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.50028777 Å) | Cite: | A RhoA structure with switch II flipped outward revealed the conformational dynamics of switch II region. J.Struct.Biol., 215, 2023
|
|
4ESP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4esp by Molmil](/molmil-images/mine/4esp) | Crystal Structure of Peanut Allergen Ara h 5 | Descriptor: | 1,2-ETHANEDIOL, ISOPROPYL ALCOHOL, Profilin | Authors: | Wang, Y, Zhang, Y.Z. | Deposit date: | 2012-04-23 | Release date: | 2013-03-06 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Crystal Structure of Peanut ( Arachis hypogaea ) Allergen Ara h 5. J.Agric.Food Chem., 61, 2013
|
|
4BX3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4bx3 by Molmil](/molmil-images/mine/4bx3) | |
6EMK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6emk by Molmil](/molmil-images/mine/6emk) | Cryo-EM Structure of Saccharomyces cerevisiae Target of Rapamycin Complex 2 | Descriptor: | Serine/threonine-protein kinase TOR2, Target of rapamycin complex 2 subunit AVO1, Target of rapamycin complex 2 subunit AVO2, ... | Authors: | Karuppasamy, M, Kusmider, B, Oliveira, T.M, Gaubitz, C, Prouteau, M, Loewith, R, Schaffitzel, C. | Deposit date: | 2017-10-02 | Release date: | 2017-12-06 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (7.9 Å) | Cite: | Cryo-EM structure of Saccharomyces cerevisiae target of rapamycin complex 2. Nat Commun, 8, 2017
|
|
1ROW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1row by Molmil](/molmil-images/mine/1row) | Structure of SSP-19, an MSP-domain protein like family member in Caenorhabditis elegans | Descriptor: | MSP-domain protein like family member | Authors: | Schormann, N, Symersky, J, Carson, M, Luo, M, Lin, G, Li, S, Qiu, S, Arabashi, A, Bunzel, B, Luo, D, Nagy, L, Gray, R, Luan, C.-H, Zhang, J, Lu, S, DeLucas, L, Southeast Collaboratory for Structural Genomics (SECSG) | Deposit date: | 2003-12-02 | Release date: | 2003-12-23 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of sperm-specific protein SSP-19 from Caenorhabditis elegans. Acta Crystallogr.,Sect.D, 60, 2004
|
|
6FSA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6fsa by Molmil](/molmil-images/mine/6fsa) | Beta-Cardiac myosin post-rigor | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, FORMIC ACID, ... | Authors: | Robert-Paganin, J, Auguin, D, Houdusse, A. | Deposit date: | 2018-02-19 | Release date: | 2018-07-25 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.33 Å) | Cite: | Hypertrophic cardiomyopathy disease results from disparate impairments of cardiac myosin function and auto-inhibition. Nat Commun, 9, 2018
|
|
1VAE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1vae by Molmil](/molmil-images/mine/1vae) | Solution structure of the PDZ domain of mouse Rhophilin-2 | Descriptor: | rhophilin, Rho GTPase binding protein 2 | Authors: | Yoneyama, M, Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2004-02-14 | Release date: | 2004-08-14 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution structure of the PDZ domain of mouse Rhophilin-2 To be Published
|
|
2ESM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2esm by Molmil](/molmil-images/mine/2esm) | Crystal Structure of ROCK 1 bound to fasudil | Descriptor: | 5-(1,4-DIAZEPAN-1-SULFONYL)ISOQUINOLINE, Rho-associated protein kinase 1 | Authors: | Jacobs, M. | Deposit date: | 2005-10-26 | Release date: | 2005-11-08 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | The Structure of Dimeric ROCK I Reveals the Mechanism for Ligand Selectivity. J.Biol.Chem., 281, 2006
|
|
1UUE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1uue by Molmil](/molmil-images/mine/1uue) | a-SPECTRIN SH3 DOMAIN (V44T, D48G MUTANT) | Descriptor: | SPECTRIN ALPHA CHAIN | Authors: | Vega, M.C, Fernandez, A, Wilmanns, M, Serrano, L. | Deposit date: | 2003-12-18 | Release date: | 2004-02-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Solvation in Protein Folding Analysis: Combination of Theoretical and Experimental Approaches Proc.Natl.Acad.Sci.USA, 101, 2004
|
|
2ETR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2etr by Molmil](/molmil-images/mine/2etr) | Crystal Structure of ROCK I bound to Y-27632 | Descriptor: | (R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXANECARBOXAMIDE, Rho-associated protein kinase 1 | Authors: | Jacobs, M. | Deposit date: | 2005-10-27 | Release date: | 2005-11-08 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The Structure of Dimeric ROCK I Reveals the Mechanism for Ligand Selectivity. J.Biol.Chem., 281, 2006
|
|
2ERZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2erz by Molmil](/molmil-images/mine/2erz) | Crystal Structure of c-AMP Dependent Kinase (PKA) bound to hydroxyfasudil | Descriptor: | 1-(1-HYDROXY-5-ISOQUINOLINESULFONYL)HOMOPIPERAZINE, cAMP-dependent protein kinase inhibitor, alpha form, ... | Authors: | Jacobs, M. | Deposit date: | 2005-10-25 | Release date: | 2005-11-08 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The Structure of Dimeric ROCK I Reveals the Mechanism for Ligand Selectivity. J.Biol.Chem., 281, 2006
|
|
1HYN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1hyn by Molmil](/molmil-images/mine/1hyn) | |
1E6G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1e6g by Molmil](/molmil-images/mine/1e6g) | A-SPECTRIN SH3 DOMAIN A11V, V23L, M25I, V53I, V58L MUTANT | Descriptor: | SPECTRIN ALPHA CHAIN, SULFATE ION | Authors: | Vega, M.C, Serrano, L. | Deposit date: | 2000-08-15 | Release date: | 2002-05-23 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Conformational Strain in the Hydrophobic Core and its Implications for Protein Folding and Design Nat.Struct.Biol., 9, 2002
|
|
6RT0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6rt0 by Molmil](/molmil-images/mine/6rt0) | cryo-em structure of alpha-synuclein fibril polymorph 2A | Descriptor: | Alpha-synuclein | Authors: | Guerrero-Ferreira, R, Taylor, N.M.I, Arteni, A.A, Melki, R, Meier, B.H, Bockmann, A, Bousset, L, Stahlberg, H. | Deposit date: | 2019-05-22 | Release date: | 2019-06-26 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Two new polymorphic structures of human full-length alpha-synuclein fibrils solved by cryo-electron microscopy. Elife, 8, 2019
|
|
7K3J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7k3j by Molmil](/molmil-images/mine/7k3j) | |
7K3K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7k3k by Molmil](/molmil-images/mine/7k3k) | |
7K3L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7k3l by Molmil](/molmil-images/mine/7k3l) | |