7PC8
| The PDZ domain of SNTG1 complexed with the phosphomimetic mutant PDZ-binding motif of RSK1 | Descriptor: | CALCIUM ION, GLYCEROL, Gamma-1-syntrophin,Annexin A2, ... | Authors: | Cousido-Siah, A, Trave, G, Gogl, G. | Deposit date: | 2021-08-03 | Release date: | 2022-04-20 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | A scalable strategy to solve structures of PDZ domains and their complexes. Acta Crystallogr D Struct Biol, 78, 2022
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7TM3
| Structure of the rabbit 80S ribosome stalled on a 2-TMD Rhodopsin intermediate in complex with the multipass translocon | Descriptor: | 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | Authors: | Kim, M.K, Lewis, A.J.O, Keenan, R.J, Hegde, R.S. | Deposit date: | 2022-01-19 | Release date: | 2022-10-19 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.25 Å) | Cite: | Mechanism of an intramembrane chaperone for multipass membrane proteins. Nature, 611, 2022
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7TUT
| Structure of the rabbit 80S ribosome stalled on a 4-TMD Rhodopsin intermediate in complex with the multipass translocon | Descriptor: | 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | Authors: | Kim, M.K, Lewis, A.J.O, Keenan, R.J, Hegde, R.S. | Deposit date: | 2022-02-03 | Release date: | 2022-10-19 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.88 Å) | Cite: | Mechanism of an intramembrane chaperone for multipass membrane proteins. Nature, 611, 2022
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4JRX
| Crystal Structure of CA5 TCR-HLA B*3505-LPEP complex | Descriptor: | Beta-2-microglobulin, CA5 TCR alpha chain, CA5 TCR beta chain, ... | Authors: | Liu, Y.C, Rossjohn, J, Gras, S. | Deposit date: | 2013-03-22 | Release date: | 2013-04-10 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Highly divergent T-cell receptor binding modes underlie specific recognition of a bulged viral peptide bound to a human leukocyte antigen class I molecule. J.Biol.Chem., 288, 2013
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2VJC
| Torpedo Californica Acetylcholinesterase In Complex With A Non Hydrolysable Substrate Analogue, 4-Oxo-N,N,N- Trimethylpentanaminium - Orthorhombic space group - Dataset A at 150K | Descriptor: | (4R)-4-HYDROXY-N,N,N-TRIMETHYLPENTAN-1-AMINIUM, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINESTERASE, ... | Authors: | Colletier, J.P, Bourgeois, D, Fournier, D, Silman, I, Sussman, J.L, Weik, M. | Deposit date: | 2007-12-09 | Release date: | 2008-07-22 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Shoot-and-Trap: Use of Specific X-Ray Damage to Study Structural Protein Dynamics by Temperature-Controlled Cryo-Crystallography. Proc.Natl.Acad.Sci.USA, 105, 2008
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7TOM
| X-ray crystal structure of glycerol dibiphytanyl glycerol tetraether - macrocyclic archaeol synthase (GDGT-MAS) from Methanocaldococcus jannaschii with bacterial lipid substrate analog, 5'deoxyadenosine, and methionine bound | Descriptor: | 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, 5'-DEOXYADENOSINE, FE (III) ION, ... | Authors: | Lloyd, C.T, Booker, S.J, Boal, A.K. | Deposit date: | 2022-01-24 | Release date: | 2022-08-31 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Discovery, structure and mechanism of a tetraether lipid synthase. Nature, 609, 2022
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4JDK
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7TOL
| X-ray crystal structure of glycerol dibiphytanyl glycerol tetraether - macrocyclic archaeol synthase (GDGT-MAS) from Methanocaldococcus jannaschii with archaeal lipid, 5'deoxyadenosine, and methionine bound | Descriptor: | 3-PHOSPHORYL-[1,2-DI-PHYTANYL]GLYCEROL, 3-[GLYCEROLYLPHOSPHONYL]-[1,2-DI-PHYTANYL]GLYCEROL, 5'-DEOXYADENOSINE, ... | Authors: | Lloyd, C.T, Booker, S.J, Boal, A.K. | Deposit date: | 2022-01-24 | Release date: | 2022-08-31 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Discovery, structure and mechanism of a tetraether lipid synthase. Nature, 609, 2022
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2VJD
| Torpedo Californica Acetylcholinesterase In Complex With A Non Hydrolysable Substrate Analogue, 4-Oxo-N,N,N- Trimethylpentanaminium - Orthorhombic space group - Dataset C at 150K | Descriptor: | (4R)-4-HYDROXY-N,N,N-TRIMETHYLPENTAN-1-AMINIUM, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINESTERASE, ... | Authors: | Colletier, J.P, Bourgeois, D, Fournier, D, Silman, I, Sussman, J.L, Weik, M. | Deposit date: | 2007-12-09 | Release date: | 2008-07-22 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Shoot-and-Trap: Use of Specific X-Ray Damage to Study Structural Protein Dynamics by Temperature-Controlled Cryo-Crystallography. Proc.Natl.Acad.Sci.USA, 105, 2008
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7U1N
| Crystal structure of the Anopheles darlingi AD-118 long form D7 salivary protein | Descriptor: | 1,2-ETHANEDIOL, 2-(2-METHOXYETHOXY)ETHANOL, 2-ETHOXYETHANOL, ... | Authors: | Alvarenga, P.H, Gittis, A.G, Garboczi, D.N, Andersen, J.F. | Deposit date: | 2022-02-21 | Release date: | 2022-05-25 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Functional aspects of evolution in a cluster of salivary protein genes from mosquitoes. Insect Biochem.Mol.Biol., 146, 2022
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7TX8
| Long form D7 protein from Anopheles darlingi with U46619 and serotonin bound | Descriptor: | (5Z)-7-{(1R,4S,5S,6R)-6-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2-oxabicyclo[2.2.1]hept-5-yl}hept-5-enoic acid, Long form D7 salivary protein, SEROTONIN | Authors: | Andersen, J.F, Alvarenga, P.H. | Deposit date: | 2022-02-08 | Release date: | 2022-06-01 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Functional aspects of evolution in a cluster of salivary protein genes from mosquitoes. Insect Biochem.Mol.Biol., 146, 2022
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7VFJ
| Cytochrome c-type biogenesis protein CcmABCD | Descriptor: | Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein B, Heme exporter protein C, ... | Authors: | Zhu, J.P, Zhang, K, Li, J, Zheng, W, Gu, M. | Deposit date: | 2021-09-13 | Release date: | 2022-11-09 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.98 Å) | Cite: | Structures of the CcmABCD heme release complex at multiple states. Nat Commun, 13, 2022
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7VFP
| Cytochrome c-type biogenesis protein CcmABCD from E. coli in complex with heme and single ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein B, ... | Authors: | Li, J, Zheng, W, Gu, M, Zhang, K, Zhu, J.P. | Deposit date: | 2021-09-13 | Release date: | 2022-11-09 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (4.03 Å) | Cite: | Structures of the CcmABCD heme release complex at multiple states. Nat Commun, 13, 2022
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4I0C
| The structure of the camelid antibody cAbHuL5 in complex with human lysozyme | Descriptor: | CHLORIDE ION, GLYCEROL, Lysozyme C, ... | Authors: | De Genst, E, Chan, P.H, Pardon, E, Kumita, J.R, Christodoulou, J, Menzer, L, Chirgadze, D.Y, Robinson, C.V, Muyldermans, S, Matagne, A, Wyns, L, Dobson, C.M, Dumoulin, M. | Deposit date: | 2012-11-16 | Release date: | 2013-10-09 | Last modified: | 2013-11-06 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | A nanobody binding to non-amyloidogenic regions of the protein human lysozyme enhances partial unfolding but inhibits amyloid fibril formation. J.Phys.Chem.B, 117, 2013
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7WH1
| structure of C elegans BCMO-2 | Descriptor: | Beta-Carotene 15,15'-MonoOxygenase, FE (III) ION, GLYCEROL, ... | Authors: | Pan, W, Liu, L. | Deposit date: | 2021-12-29 | Release date: | 2022-02-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural and Functional Analysis of Nonheme Iron Enzymes BCMO-1 and BCMO-2 from Caenorhabditis elegans . Front Mol Biosci, 9, 2022
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7WH0
| structure of C elegans BCMO-1 | Descriptor: | Beta-Carotene 15,15'-MonoOxygenase, FE (III) ION, GLYCEROL, ... | Authors: | Pan, W, Liu, L. | Deposit date: | 2021-12-29 | Release date: | 2022-02-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural and Functional Analysis of Nonheme Iron Enzymes BCMO-1 and BCMO-2 from Caenorhabditis elegans . Front Mol Biosci, 9, 2022
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7W5O
| Crystal structure of ERK2 with an allosteric inhibitor | Descriptor: | (2R,3R,4S,5R)-2-(4-AMINO-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-3,4-DIOL, 13-[4-({Imidazo[1,2-a]pyridin-2-yl}methoxy)phenyl]-4,8-dioxa-12,14,16,18-tetraazatetracyclo[9.7.0.0^{3,9}.0^{12,17}]octadeca-1(11),2,9,15,17-pentaen-15-amine, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Yoshida, M, Kinoshita, T. | Deposit date: | 2021-11-30 | Release date: | 2022-02-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Identification of a novel target site for ATP-independent ERK2 inhibitors. Biochem.Biophys.Res.Commun., 593, 2022
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2VJA
| Torpedo Californica Acetylcholinesterase In Complex With A Non Hydrolysable Substrate Analogue, 4-Oxo-N,N,N- Trimethylpentanaminium - Orthorhombic space group - Dataset A at 100K | Descriptor: | (4R)-4-HYDROXY-N,N,N-TRIMETHYLPENTAN-1-AMINIUM, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINESTERASE, ... | Authors: | Colletier, J.P, Bourgeois, D, Fournier, D, Silman, I, Sussman, J.L, Weik, M. | Deposit date: | 2007-12-09 | Release date: | 2008-07-22 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Shoot-and-Trap: Use of Specific X-Ray Damage to Study Structural Protein Dynamics by Temperature-Controlled Cryo-Crystallography. Proc.Natl.Acad.Sci.USA, 105, 2008
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4IMI
| Novel Modifications on C-terminal Domain of RNA Polymerase II can Fine- tune the Phosphatase Activity of Ssu72. | Descriptor: | CG14216, CTD, PHOSPHATE ION, ... | Authors: | Luo, Y, Yogesha, S.D, Zhang, Y. | Deposit date: | 2013-01-03 | Release date: | 2013-08-07 | Last modified: | 2013-10-30 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Novel Modifications on C-terminal Domain of RNA Polymerase II Can Fine-tune the Phosphatase Activity of Ssu72. Acs Chem.Biol., 8, 2013
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7RUJ
| E. coli cysteine desulfurase SufS N99A | Descriptor: | CHLORIDE ION, Cysteine desulfurase, PYRIDOXAL-5'-PHOSPHATE | Authors: | Dunkle, J.A, Gogar, R, Frantom, P.A. | Deposit date: | 2021-08-17 | Release date: | 2023-01-25 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The beta-latch structural element of the SufS cysteine desulfurase mediates active site accessibility and SufE transpersulfurase positioning. J.Biol.Chem., 299, 2023
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7RW3
| E. coli cysteine desulfurase SufS N99D | Descriptor: | Cysteine desulfurase, PYRIDOXAL-5'-PHOSPHATE | Authors: | Dunkle, J.A, Gogar, R, Frantom, P.A. | Deposit date: | 2021-08-19 | Release date: | 2023-01-25 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The beta-latch structural element of the SufS cysteine desulfurase mediates active site accessibility and SufE transpersulfurase positioning. J.Biol.Chem., 299, 2023
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4LYR
| Glycoside Hydrolase Family 5 Mannosidase from Rhizomucor miehei, E301A mutant | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Exo-beta-1,4-mannosidase | Authors: | Jiang, Z.Q, Zhou, P, Yang, S.Q, Liu, Y, Yan, Q.J. | Deposit date: | 2013-07-31 | Release date: | 2014-08-06 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural insights into the substrate specificity and transglycosylation activity of a fungal glycoside hydrolase family 5 beta-mannosidase. Acta Crystallogr.,Sect.D, 70, 2014
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5YZ5
| Crystal Structure of Human CRMP-2 with T509D-T514D-S518D-S522D mutations | Descriptor: | Dihydropyrimidinase-related protein 2, SULFATE ION | Authors: | Imasaki, T, Sumi, T, Aoki, M, Sakai, N, Nitta, E, Shirouzu, M, Nitta, R. | Deposit date: | 2017-12-13 | Release date: | 2018-03-21 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural Insights into the Altering Function of CRMP2 by Phosphorylation. Cell Struct. Funct., 43, 2018
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5YZA
| Crystal Structure of Human CRMP-2 with S522D mutation | Descriptor: | Dihydropyrimidinase-related protein 2 | Authors: | Sumi, T, Imasaki, T, Aoki, M, Sakai, N, Nitta, E, Shirouzu, M, Nitta, R. | Deposit date: | 2017-12-13 | Release date: | 2018-03-21 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural Insights into the Altering Function of CRMP2 by Phosphorylation. Cell Struct. Funct., 43, 2018
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5I8D
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