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9CC9
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BU of 9cc9 by Molmil
Dodecameric state of the NRC4 resistosome
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, NLR-required for cell death 4
Authors:Liu, F, Yang, Z, Nogales, E, Staskawicz, B.J.
Deposit date:2024-06-21
Release date:2024-09-11
Last modified:2024-09-18
Method:ELECTRON MICROSCOPY (3.54 Å)
Cite:Activation of the helper NRC4 immune receptor forms a hexameric resistosome.
Cell, 187, 2024
9C9M
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BU of 9c9m by Molmil
HIV-1 intasome core bound with DTG
Descriptor: (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, Integrase, MAGNESIUM ION, ...
Authors:Li, M, Craigie, R.
Deposit date:2024-06-14
Release date:2024-07-31
Last modified:2024-08-07
Method:ELECTRON MICROSCOPY (2.01 Å)
Cite:HIV-1 Intasomes Assembled with Excess Integrase C-Terminal Domain Protein Facilitate Structural Studies by Cryo-EM and Reveal the Role of the Integrase C-Terminal Tail in HIV-1 Integration.
Viruses, 16, 2024
9ILV
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BU of 9ilv by Molmil
Structure of the bacteriophage T5 connector complex
Descriptor: Tail tube terminator protein p142
Authors:Peng, Y.N, Liu, H.R.
Deposit date:2024-07-01
Release date:2024-09-04
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Structures of Mature and Urea-Treated Empty Bacteriophage T5: Insights into Siphophage Infection and DNA Ejection.
Int J Mol Sci, 25, 2024
9B90
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BU of 9b90 by Molmil
Cryo-EM structure of the human TRPM4 channel in complex with calcium and ATP at 37 degrees Celsius
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Transient receptor potential cation channel subfamily M member 4
Authors:Hu, J, Lu, W, Du, J.
Deposit date:2024-04-01
Release date:2024-05-15
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Physiological temperature drives TRPM4 ligand recognition and gating.
Nature, 630, 2024
9EM7
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BU of 9em7 by Molmil
Oligomeric structure of SynDLP in presence of GTP
Descriptor: Slr0869 protein
Authors:Junglas, B, Gewehr, L, Schoennenbeck, P, Schneider, D, Sachse, C.
Deposit date:2024-03-07
Release date:2024-09-11
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural basis for GTPase activity and conformational changes of the bacterial dynamin-like protein SynDLP.
Cell Rep, 43, 2024
9B1K
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BU of 9b1k by Molmil
Urate bound human URAT1 in the occluded state
Descriptor: Solute carrier family 22 member 12, URIC ACID
Authors:Dai, Y, Lee, C.H.
Deposit date:2024-03-13
Release date:2024-09-18
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Transport mechanism and structural pharmacology of human urate transporter URAT1.
Cell Res., 2024
9ILP
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BU of 9ilp by Molmil
Structure of the bacteriophage T5 portal complex
Descriptor: Head completion protein, Portal protein pb7
Authors:Peng, Y.N, Liu, H.R.
Deposit date:2024-07-01
Release date:2024-09-18
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structures of Mature and Urea-Treated Empty Bacteriophage T5: Insights into Siphophage Infection and DNA Ejection.
Int J Mol Sci, 25, 2024
8YSH
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BU of 8ysh by Molmil
MERS-CoV RBD in complex with nanobody Nb14
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Nb14, Spike glycoprotein, ...
Authors:Wang, Y.X, Ma, S.
Deposit date:2024-03-23
Release date:2024-09-11
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structure defining of ultrapotent neutralizing nanobodies against MERS-CoV with novel epitopes on receptor binding domain.
Plos Pathog., 20, 2024
9INY
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BU of 9iny by Molmil
Structure of bacteriophage T5 tail tube
Descriptor: Tail tube protein pb6
Authors:Peng, Y.N, Liu, H.R.
Deposit date:2024-07-08
Release date:2024-09-04
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structures of Mature and Urea-Treated Empty Bacteriophage T5: Insights into Siphophage Infection and DNA Ejection.
Int J Mol Sci, 25, 2024
9C3U
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BU of 9c3u by Molmil
Crystal structure of DNA N6-Adenine Methyltransferase M.BceJIV from Burkholderia cenocepacia in complex with duplex DNA substrate containing GTTTAC as recognition sequence
Descriptor: DNA1, DNA2, Methyltransferase, ...
Authors:Kottur, J, Quintana-Feliciano, R, Aggarwal, A.K.
Deposit date:2024-06-02
Release date:2024-09-11
Last modified:2024-09-25
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Burkholderia cenocepacia epigenetic regulator M.BceJIV simultaneously engages two DNA recognition sequences for methylation.
Nat Commun, 15, 2024
9B8Z
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BU of 9b8z by Molmil
Cryo-EM structure of the human TRPM4 channel subunit in complex with calcium and decavanadate at 37 degrees Celsius
Descriptor: CALCIUM ION, DECAVANADATE, Transient receptor potential cation channel subfamily M member 4
Authors:Hu, J, Lu, W, Du, J.
Deposit date:2024-04-01
Release date:2024-05-15
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Physiological temperature drives TRPM4 ligand recognition and gating.
Nature, 630, 2024
9AXE
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BU of 9axe by Molmil
Cryo-EM reconstruction of a Staphylococcus aureus oleate hydratase (OhyA) assembly of dimers bound to a liposome
Descriptor: Oleate hydratase
Authors:Oldham, M.L, Qayyum, M.Z, Radka, C.D.
Deposit date:2024-03-06
Release date:2024-08-21
Last modified:2024-09-11
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Cryo-EM reconstruction of oleate hydratase bound to a phospholipid membrane bilayer.
J.Struct.Biol., 216, 2024
5AB8
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BU of 5ab8 by Molmil
High resolution X-ray structure of the N-terminal truncated form (residues 1-11) of Mycobacterium tuberculosis HbN
Descriptor: ACETATE ION, FORMIC ACID, GLYCEROL, ...
Authors:Pesce, A, Bustamante, J.P, Bidon-Chanal, A, Boechi, L, Estrin, D.A, Luque, F.J, Sebilo, A, Guertin, M, Bolognesi, M, Ascenzi, P, Nardini, M.
Deposit date:2015-08-04
Release date:2015-11-04
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:The N-Terminal Pre-A Region of Mycobacterium Tuberculosis 2/2Hbn Promotes No-Dioxygenase Activity.
FEBS J., 283, 2016
9B8X
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BU of 9b8x by Molmil
Cryo-EM structure of the human TRPM4 channel subunit in complex with calcium 37 degrees Celsius
Descriptor: CALCIUM ION, Transient receptor potential cation channel subfamily M member 4
Authors:Hu, J, Lu, W, Du, J.
Deposit date:2024-04-01
Release date:2024-05-15
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Physiological temperature drives TRPM4 ligand recognition and gating.
Nature, 630, 2024
9ESA
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BU of 9esa by Molmil
Aurora-C with SER mutation in complex with INCENP peptide
Descriptor: 1,2-ETHANEDIOL, Aurora kinase C, Inner centromere protein
Authors:Hillig, R.C.
Deposit date:2024-03-26
Release date:2024-09-11
Last modified:2024-09-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Surface-mutagenesis strategies to enable structural biology crystallization platforms.
Acta Crystallogr D Struct Biol, 80, 2024
9F3D
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BU of 9f3d by Molmil
Single acyclic phosphonate nucleotide (S)-ZNA modification on DNA hairpin
Descriptor: C modifed (S)-ZNA
Authors:Li, X, Groaz, E, Herdewijn, P, Lescrinier, E.
Deposit date:2024-04-25
Release date:2024-06-05
Last modified:2024-07-10
Method:SOLUTION NMR
Cite:Impact of Single Acyclic Phosphonate Nucleotide (ZNA) Modifications on DNA Duplex Stability.
Chemistry, 30, 2024
8YSF
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BU of 8ysf by Molmil
MERS-CoV RBD in complex with nanobody Nb9
Descriptor: Nb9, Spike glycoprotein
Authors:Wang, Y.X, Ma, S.
Deposit date:2024-03-22
Release date:2024-09-11
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:Structure defining of ultrapotent neutralizing nanobodies against MERS-CoV with novel epitopes on receptor binding domain.
Plos Pathog., 20, 2024
9B1H
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BU of 9b1h by Molmil
Human urate transporter 1 URAT1 in complex with lesinurad
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Solute carrier family 22 member 12, lesinurad
Authors:Dai, Y, Lee, C.H.
Deposit date:2024-03-13
Release date:2024-09-18
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Transport mechanism and structural pharmacology of human urate transporter URAT1.
Cell Res., 2024
9BF6
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BU of 9bf6 by Molmil
Cryo-EM structure of the HIV-1 WITO IDL Env trimer in complex with PGT122 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, Envelope glycoprotein gp41, ...
Authors:Gorman, J, Kwong, P.D.
Deposit date:2024-04-16
Release date:2024-07-31
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Design of soluble HIV-1 envelope trimers free of covalent gp120-gp41 bonds with prevalent native-like conformation.
Cell Rep, 43, 2024
9FLA
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BU of 9fla by Molmil
SOLUTION STRUCTURE OF 6XHIS-TAGGED WILD-TYPE GAUSSIA LUCIFERASE
Descriptor: Luciferase
Authors:Dijkema, F.M, Prestel, A, Winther, J.R, Teilum, K.
Deposit date:2024-06-04
Release date:2024-07-17
Last modified:2024-07-31
Method:SOLUTION NMR
Cite:A suicidal and extensively disordered luciferase with a bright luminescence.
Protein Sci., 33, 2024
9B1F
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BU of 9b1f by Molmil
Human urate transporter 1 URAT1 in apo state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Solute carrier family 22 member 12
Authors:Dai, Y, Lee, C.H.
Deposit date:2024-03-13
Release date:2024-09-18
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Transport mechanism and structural pharmacology of human urate transporter URAT1.
Cell Res., 2024
9F3E
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BU of 9f3e by Molmil
Single acyclic phosphonate nucleotide (R)-ZNA modification on DNA duplex
Descriptor: C modified (R)-ZNA
Authors:Li, X, Groaz, E, Herdewyn, P, Lescrinier, E.
Deposit date:2024-04-25
Release date:2024-06-05
Last modified:2024-07-10
Method:SOLUTION NMR
Cite:Impact of Single Acyclic Phosphonate Nucleotide (ZNA) Modifications on DNA Duplex Stability.
Chemistry, 30, 2024
9B1O
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BU of 9b1o by Molmil
Pyrazinoate bound human URAT1 in the inward-facing state (site3)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, PYRAZINE-2-CARBOXYLIC ACID, Solute carrier family 22 member 12
Authors:Dai, Y, Lee, C.H.
Deposit date:2024-03-13
Release date:2024-09-18
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Transport mechanism and structural pharmacology of human urate transporter URAT1.
Cell Res., 2024
9EM9
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BU of 9em9 by Molmil
Structure of SynDLP MGD with GMPPNP
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Slr0869 protein
Authors:Junglas, B, Gewehr, L, Schoennenbeck, P, Schneider, D, Sachse, C.
Deposit date:2024-03-07
Release date:2024-09-11
Method:ELECTRON MICROSCOPY (3.76 Å)
Cite:Structural basis for GTPase activity and conformational changes of the bacterial dynamin-like protein SynDLP.
Cell Rep, 43, 2024
9B1N
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BU of 9b1n by Molmil
Pyrazinoate bound human URAT1 in the inward-facing state (site2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, PYRAZINE-2-CARBOXYLIC ACID, Solute carrier family 22 member 12
Authors:Dai, Y, Lee, C.H.
Deposit date:2024-03-13
Release date:2024-09-18
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Transport mechanism and structural pharmacology of human urate transporter URAT1.
Cell Res., 2024

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数据于2024-09-25公开中

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