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6XH3
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BU of 6xh3 by Molmil
Co-crystal structure of HIV-1 TAR RNA in complex with lab-evolved RRM TBP6.3
Descriptor: TAR BINDING PROTEIN TBP 6.3, TRANS-ACTIVATION RESPONSE ELEMENT
Authors:Chavali, S.S, Jenkins, J.L, Wedekind, J.E.
Deposit date:2020-06-18
Release date:2020-10-14
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.353 Å)
Cite:Co-crystal structures of HIV TAR RNA bound to lab-evolved proteins show key roles for arginine relevant to the design of cyclic peptide TAR inhibitors.
J.Biol.Chem., 295, 2020
6XH2
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BU of 6xh2 by Molmil
Co-crystal structure of HIV-1 TAR RNA in complex with lab-evolved RRM 6.6
Descriptor: TAR-BINDING PROTEIN 6.6, TRANS-ACTIVATION RESPONSE ELEMENT
Authors:Chavali, S.S, Jenkins, J.L, Wedekind, J.E.
Deposit date:2020-06-18
Release date:2020-10-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Co-crystal structures of HIV TAR RNA bound to lab-evolved proteins show key roles for arginine relevant to the design of cyclic peptide TAR inhibitors.
J.Biol.Chem., 295, 2020
6XH1
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BU of 6xh1 by Molmil
Co-crystal structure of HIV-1 TAR RNA in complex with lab-evolved RRM TBP6.7 mutant
Descriptor: TAR binding protein mutant 6.7 Q48R/T50R, TRANS-ACTIVATION RESPONSE ELEMENT
Authors:Chavali, S.S, Jenkins, J.L, Wedekind, J.E.
Deposit date:2020-06-18
Release date:2020-10-14
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.601 Å)
Cite:Co-crystal structures of HIV TAR RNA bound to lab-evolved proteins show key roles for arginine relevant to the design of cyclic peptide TAR inhibitors.
J.Biol.Chem., 295, 2020
6XH0
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BU of 6xh0 by Molmil
Co-crystal structure of HIV-1 TAR RNA in complex with lab-evolved RRM TBP6.9
Descriptor: MAGNESIUM ION, TAR binding protein 6.9, TRANS-ACTIVATION RESPONSE ELEMENT
Authors:Chavali, S.S, Jenkins, J.L, Wedekind, J.E.
Deposit date:2020-06-18
Release date:2020-10-14
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Co-crystal structures of HIV TAR RNA bound to lab-evolved proteins show key roles for arginine relevant to the design of cyclic peptide TAR inhibitors.
J.Biol.Chem., 295, 2020
2F8E
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BU of 2f8e by Molmil
Foot and Mouth Disease Virus RNA-dependent RNA polymerase in complex with uridylylated VPg protein
Descriptor: MAGNESIUM ION, MANGANESE (II) ION, RNA-dependent RNA polymerase, ...
Authors:Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N.
Deposit date:2005-12-02
Release date:2006-03-28
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The structure of a protein primer-polymerase complex in the initiation of genome replication
Embo J., 25, 2006
3H3D
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BU of 3h3d by Molmil
Drosophila Pumilio RNA binding domain (Puf domain)
Descriptor: Maternal protein pumilio
Authors:Edwards, T.A, Aggarwal, A.K, Wharton, R.P.
Deposit date:2009-04-16
Release date:2009-04-28
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of Pumilio reveals similarity between RNA and peptide binding motifs.
Cell(Cambridge,Mass.), 105, 2001
4DWQ
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BU of 4dwq by Molmil
RNA ligase RtcB-GMP/Mn(2+) complex
Descriptor: GLYCEROL, GUANOSINE-5'-MONOPHOSPHATE, MALONATE ION, ...
Authors:Okada, C, Xia, S, Englert, M, Yao, M, Soll, D, Wang, J.
Deposit date:2012-02-26
Release date:2012-09-05
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural and mechanistic insights into guanylylation of RNA-splicing ligase RtcB joining RNA between 3'-terminal phosphate and 5'-OH.
Proc.Natl.Acad.Sci.USA, 109, 2012
2CJQ
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BU of 2cjq by Molmil
Bovine viral diarrhea virus CP7-R12 RNA-dependent RNA polymerase
Descriptor: RNA-DIRECTED RNA POLYMERASE
Authors:Choi, K.H, Gallei, A, Becher, P, Rossmann, M.G.
Deposit date:2006-04-05
Release date:2006-07-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The Structure of Bovine Viral Diarrhea Virus RNA-Dependent RNA Polymerase and its Amino-Terminal Domain.
Structure, 14, 2006
6C8U
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BU of 6c8u by Molmil
Solution structure of Musashi2 RRM1
Descriptor: RNA-binding protein Musashi homolog 2
Authors:Xing, M, Lan, L, Douglas, J.T, Gao, P, Hanzlik, R.P, Xu, L.
Deposit date:2018-01-25
Release date:2019-01-30
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Crystal and solution structures of human oncoprotein Musashi-2 N-terminal RNA recognition motif 1.
Proteins, 2019
5U0Q
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BU of 5u0q by Molmil
RNA-DNA heptamer duplex with one 2'-5'-linkage
Descriptor: COBALT (II) ION, DNA/RNA (5'-R(*GP*GP*AP*GP*C)-D(P*T)-R(P*A)-3'), MAGNESIUM ION, ...
Authors:Luo, Z, Sheng, J.
Deposit date:2016-11-26
Release date:2017-11-29
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:RNA-DNA heptamer duplex with one 2'-5'-linkage
To Be Published
4RNP
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BU of 4rnp by Molmil
BACTERIOPHAGE T7 RNA POLYMERASE, HIGH SALT CRYSTAL FORM, LOW TEMPERATURE DATA, ALPHA-CARBONS ONLY
Descriptor: RNA POLYMERASE
Authors:Liu, Z.J, Sousa, R, Rose, J.P, Wang, B.C.
Deposit date:1997-09-11
Release date:1997-12-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of bacteriophage T7 RNA polymerase at 3.3 A resolution.
Nature, 364, 1993
8THV
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BU of 8thv by Molmil
FARFAR-NMR ensemble of HIV-1 TAR with apical loop capturing ground and excited conformational states
Descriptor: RNA (29-MER)
Authors:Roy, R, Geng, A, Shi, H, Merriman, D.K, Dethoff, E.A, Salmon, L, Al-Hashimi, H.M.
Deposit date:2023-07-18
Release date:2023-08-02
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Kinetic Resolution of the Atomic 3D Structures Formed by Ground and Excited Conformational States in an RNA Dynamic Ensemble.
J.Am.Chem.Soc., 145, 2023
5NPA
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BU of 5npa by Molmil
Solution structure of Drosophila melanogaster Loquacious dsRBD2
Descriptor: Loquacious
Authors:Tants, J.-N, Fesser, S, Kern, T, Stehle, R, Geerlof, A, Wunderlich, C, Boettcher, R, Kunzelmann, S, Lange, O, Kreutz, C, Foerstemann, K, Sattler, M.
Deposit date:2017-04-16
Release date:2017-10-04
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Molecular basis for asymmetry sensing of siRNAs by the Drosophila Loqs-PD/Dcr-2 complex in RNA interference.
Nucleic Acids Res., 45, 2017
5NPG
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BU of 5npg by Molmil
Solution structure of Drosophila melanogaster Loquacious dsRBD1
Descriptor: Loquacious, isoform F
Authors:Tants, J.-N, Fesser, S, Kern, T, Stehle, R, Geerlof, A, Wunderlich, C, Hartlmuller, C, Boettcher, R, Kunzelmann, S, Lange, O, Kreutz, C, Foerstemann, K, Sattler, M.
Deposit date:2017-04-16
Release date:2017-10-04
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Molecular basis for asymmetry sensing of siRNAs by the Drosophila Loqs-PD/Dcr-2 complex in RNA interference.
Nucleic Acids Res., 45, 2017
3IM2
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BU of 3im2 by Molmil
Structure of the C-terminal Sec63 unit of yeast Brr2, P41212 Form
Descriptor: Pre-mRNA-splicing helicase BRR2, TETRAETHYLENE GLYCOL
Authors:Pena, V, Hrmann, R.L, Wahl, M.C.
Deposit date:2009-08-09
Release date:2009-08-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Common Design Principles in the Spliceosomal RNA Helicase Brr2 and in the Hel308 DNA Helicase
To be Published
3IM1
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BU of 3im1 by Molmil
Structure of the C-terminal Sec63 unit of yeast Brr2, P212121 Form
Descriptor: Pre-mRNA-splicing helicase BRR2
Authors:Pena, V, Hrmann, R.L, Wahl, M.C.
Deposit date:2009-08-09
Release date:2009-08-25
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Common Design Principles in the Spliceosomal RNA Helicase Brr2 and in the Hel308 DNA Helicase
To be Published
6MJ0
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BU of 6mj0 by Molmil
Crystal structure of the complete turnip yellow mosaic virus 3'UTR
Descriptor: RNA (101-MER)
Authors:Hartwick, E.W, Costantino, D.A, MacFadden, A, Nix, J.C, Tian, S, Das, R, Kieft, J.S.
Deposit date:2018-09-20
Release date:2019-01-09
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Ribosome-induced RNA conformational changes in a viral 3'-UTR sense and regulate translation levels.
Nat Commun, 9, 2018
6BOG
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BU of 6bog by Molmil
Crystal structure of RapA, a Swi2/Snf2 protein that recycles RNA polymerase during transcription
Descriptor: RNA polymerase-associated protein RapA, SULFATE ION
Authors:Shaw, G.X, Gan, J, Zhou, Y.N, Zhang, R, Joachimiak, A, Jin, D.J, Ji, X.
Deposit date:2017-11-20
Release date:2017-12-13
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.205 Å)
Cite:Structure of RapA, a Swi2/Snf2 protein that recycles RNA polymerase during transcription.
Structure, 16, 2008
2B7E
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BU of 2b7e by Molmil
First FF domain of Prp40 Yeast Protein
Descriptor: Pre-mRNA processing protein PRP40
Authors:Gasch, A, Wiesner, S, Martin-Malpartida, P, Ramirez-Espain, X, Ruiz, L, Macias, M.J.
Deposit date:2005-10-04
Release date:2005-11-01
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The structure of Prp40 FF1 domain and its interaction with the crn-TPR1 motif of Clf1 gives a new insight into the binding mode of FF domains.
J.Biol.Chem., 281, 2006
5UZZ
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BU of 5uzz by Molmil
Structure of wild type pre-miR21 apical loop
Descriptor: 14-mer Peptide, pre-miR21
Authors:Shortridge, M.D, Varani, G.
Deposit date:2017-02-27
Release date:2017-06-14
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:A Macrocyclic Peptide Ligand Binds the Oncogenic MicroRNA-21 Precursor and Suppresses Dicer Processing.
ACS Chem. Biol., 12, 2017
5V1L
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BU of 5v1l by Molmil
Structure of S-GNA dodecamer
Descriptor: RNA (5'-R(*CP*GP*CP*GP*AP*AP*UP*(ZTH)P*AP*GP*CP*G)-3'), SPERMINE, STRONTIUM ION
Authors:Pallan, P.S, Egli, M.
Deposit date:2017-03-02
Release date:2017-06-14
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Chirality Dependent Potency Enhancement and Structural Impact of Glycol Nucleic Acid Modification on siRNA.
J. Am. Chem. Soc., 139, 2017
5V1K
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BU of 5v1k by Molmil
Structure of R-GNA dodecamer
Descriptor: RNA (5'-R(*CP*GP*CP*GP*AP*AP*(5BU)P*(8RJ)P*AP*GP*CP*G)-3')
Authors:Pallan, P.S, Egli, M.
Deposit date:2017-03-02
Release date:2017-06-21
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.18 Å)
Cite:Chirality Dependent Potency Enhancement and Structural Impact of Glycol Nucleic Acid Modification on siRNA.
J. Am. Chem. Soc., 2017
3SBG
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BU of 3sbg by Molmil
Crystal structure of a Prp8 C-terminal fragment
Descriptor: Pre-mRNA-splicing factor 8
Authors:Weber, G, Santos, K, Holton, N, Wahl, M.C.
Deposit date:2011-06-04
Release date:2012-04-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.28 Å)
Cite:Mechanism for Aar2p function as a U5 snRNP assembly factor.
Genes Dev., 25, 2011
2NOQ
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BU of 2noq by Molmil
Structure of ribosome-bound cricket paralysis virus IRES RNA
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S5, ...
Authors:Schuler, M, Connell, S.R, Lescoute, A, Giesebrecht, J, Dabrowski, M, Schroeer, B, Mielke, T, Penczek, P.A, Westhof, E, Spahn, C.M.T.
Deposit date:2006-10-26
Release date:2006-11-21
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (7.3 Å)
Cite:Structure of the ribosome-bound cricket paralysis virus IRES RNA.
Nat.Struct.Mol.Biol., 13, 2006
8PXS
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BU of 8pxs by Molmil
Short RNA binding to peptide amyloids
Descriptor: RNA (5'-R(P*GP*UP*CP*A)-3'), VAL-ALA-GLN-ALA-GLN-ILE-ASN-ILE
Authors:Rout, S.K, Cadalbert, R, Schroder, N, Wiegand, T, Zehnder, J, Gampp, O, Guntert, P, Kringler, D, Kreutz, C, Knorlein, A, Hall, J, Greenwald, J, Riek, R.
Deposit date:2023-07-24
Release date:2023-10-18
Method:SOLID-STATE NMR
Cite:An Analysis of Nucleotide-Amyloid Interactions Reveals Selective Binding to Codon-Sized RNA.
J.Am.Chem.Soc., 145, 2023

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数据于2024-07-10公开中

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