6SES
 
 | | Tubulin-B2 complex | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Guo, B, Rodriguez-Gabin, A, Prota, A.E, Muehlethaler, T, Zhang, N, Ye, K, Steinmetz, M.O, Band Horwitz, S, Smith III, A.B, McDaid, H.M. | | Deposit date: | 2019-07-30 | | Release date: | 2020-07-08 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural Refinement of the Tubulin Ligand (+)-Discodermolide to Attenuate Chemotherapy-Mediated Senescence.
Mol.Pharmacol., 98, 2020
|
|
6SI9
 | | FtsZ-refold | | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, Cell division protein FtsZ, ... | | Authors: | Fernandez-Tornero, C, Andreu, J.M, Ruiz, F.M. | | Deposit date: | 2019-08-09 | | Release date: | 2020-02-19 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Nucleotide-induced folding of cell division protein FtsZ from Staphylococcus aureus.
Febs J., 287, 2020
|
|
6S9E
 | | Tubulin-GDP.AlF complex | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ALUMINUM FLUORIDE, CALCIUM ION, ... | | Authors: | Oliva, M.A, Estevez-Gallego, J, Diaz, J.F, Prota, A.E, Steinmetz, M.O, Balaguer, F.A, Lucena-Agell, D. | | Deposit date: | 2019-07-12 | | Release date: | 2020-02-19 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Structural model for differential cap maturation at growing microtubule ends.
Elife, 9, 2020
|
|
6RVM
 | | Cell division protein FtsZ from Staphylococcus aureus, apo form | | Descriptor: | CHLORIDE ION, Cell division protein FtsZ, GLYCEROL, ... | | Authors: | Fernandez-Tornero, C, Andreu, J.M, Canosa-Valls, A.J. | | Deposit date: | 2019-05-31 | | Release date: | 2020-02-19 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.155 Å) | | Cite: | Nucleotide-induced folding of cell division protein FtsZ from Staphylococcus aureus.
Febs J., 287, 2020
|
|
6RFD
 | |
6S8M
 | | S. pombe microtubule decorated with Cut7 motor domain in the AMPPNP state | | Descriptor: | 7,11-DIHYDROXY-8,8,10,12,16-PENTAMETHYL-3-[1-METHYL-2-(2-METHYL-THIAZOL-4-YL)VINYL]-4,17-DIOXABICYCLO[14.1.0]HEPTADECANE-5,9-DIONE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Moores, C.A, von Loeffelholz, O. | | Deposit date: | 2019-07-10 | | Release date: | 2019-08-21 | | Last modified: | 2025-07-09 | | Method: | ELECTRON MICROSCOPY (4.5 Å) | | Cite: | Cryo-EM Structure (4.5- angstrom ) of Yeast Kinesin-5-Microtubule Complex Reveals a Distinct Binding Footprint and Mechanism of Drug Resistance.
J.Mol.Biol., 431, 2019
|
|
6REV
 | |
6RF2
 | |
6QUS
 | | HsCKK (human CAMSAP1) decorated 13pf taxol-GDP microtubule | | Descriptor: | Calmodulin-regulated spectrin-associated protein 1, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Atherton, J.M, Luo, Y, Xiang, S, Yang, C, Jiang, K, Stangier, M, Vemu, A, Cook, A, Wang, S, Roll-Mecak, A, Steinmetz, M.O, Akhmanova, A, Baldus, M, Moores, C.A. | | Deposit date: | 2019-02-28 | | Release date: | 2019-11-27 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structural determinants of microtubule minus end preference in CAMSAP CKK domains.
Nat Commun, 10, 2019
|
|
6RVN
 | | aFtsz-GDP-Wat | | Descriptor: | CALCIUM ION, Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE | | Authors: | Fernandez-Tornero, C, Andreu, J.M. | | Deposit date: | 2019-05-31 | | Release date: | 2020-02-19 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.242 Å) | | Cite: | Nucleotide-induced folding of cell division protein FtsZ from Staphylococcus aureus.
Febs J., 287, 2020
|
|
6RZA
 | | Cryo-EM structure of the human inner arm dynein DNAH7 microtubule binding domain bound to microtubules | | Descriptor: | Cytoplasmic dynein 1 heavy chain 1,Dynein heavy chain 7, axonemal,Cytoplasmic dynein 1 heavy chain 1, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Lacey, S.E, He, S, Scheres, S.H.W, Carter, A.P. | | Deposit date: | 2019-06-13 | | Release date: | 2019-07-10 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (4.5 Å) | | Cite: | Cryo-EM of dynein microtubule-binding domains shows how an axonemal dynein distorts the microtubule.
Elife, 8, 2019
|
|
6RVP
 | | SaFtsz-GDP-MetPyr | | Descriptor: | 1-methylpyrrolidin-2-one, CALCIUM ION, Cell division protein FtsZ, ... | | Authors: | Fernandez-Tornero, C, Andreu, J.M. | | Deposit date: | 2019-05-31 | | Release date: | 2020-02-19 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.16 Å) | | Cite: | Nucleotide-induced folding of cell division protein FtsZ from Staphylococcus aureus.
Febs J., 287, 2020
|
|
6QQN
 | | Tubulin-TH588 complex | | Descriptor: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | | Authors: | Patterson, J.C, Joughin, B.A, Prota, A.E, Muehlethaler, T, Jonas, O.H, Whitman, M.A, Varmeh, S, Chen, S, Balk, S.P, Steinmetz, M.O, Lauffenburger, D.A, Yaffe, M.B. | | Deposit date: | 2019-02-18 | | Release date: | 2019-07-24 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.301 Å) | | Cite: | VISAGE Reveals a Targetable Mitotic Spindle Vulnerability in Cancer Cells.
Cell Syst, 9, 2019
|
|
6QUY
 | | NgCKK (N.Gruberi CKK) decorated 13pf taxol-GDP microtubule | | Descriptor: | CKK domain protein, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Atherton, J.M, Luo, Y, Xiang, S, Yang, C, Jiang, K, Stangier, M, Vemu, A, Cook, A, Wang, S, Roll-Mecak, A, Steinmetz, M.O, Akhmanova, A, Baldus, M, Moores, C.A. | | Deposit date: | 2019-02-28 | | Release date: | 2019-11-27 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Structural determinants of microtubule minus end preference in CAMSAP CKK domains.
Nat Commun, 10, 2019
|
|
6QVE
 | | NgCKK (Naegleria Gruberi CKK) decorated 14pf taxol-GDP microtubule | | Descriptor: | Beta1-tubulin, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Atherton, J.M, Luo, Y, Xiang, S, Yang, C, Jiang, K, Stangier, M, Vemu, A, Cook, A, Wang, S, Roll-Mecak, A, Steinmetz, M.O, Akhmanova, A, Baldus, M, Moores, C.A. | | Deposit date: | 2019-03-01 | | Release date: | 2019-11-27 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structural determinants of microtubule minus end preference in CAMSAP CKK domains.
Nat Commun, 10, 2019
|
|
6RVQ
 | | SaFtsz-GDP-EthGLy | | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, Cell division protein FtsZ, ... | | Authors: | Fernandez-Tornero, C, Andreu, J.M. | | Deposit date: | 2019-05-31 | | Release date: | 2020-02-19 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.136 Å) | | Cite: | Nucleotide-induced folding of cell division protein FtsZ from Staphylococcus aureus.
Febs J., 287, 2020
|
|
6TDE
 | | Tubulin-inhibitor complex | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Varela, P.F, Gigant, B. | | Deposit date: | 2019-11-08 | | Release date: | 2020-09-02 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.286 Å) | | Cite: | Discovery of dihydrofuranoallocolchicinoids - Highly potent antimitotic agents with low acute toxicity.
Eur.J.Med.Chem., 207, 2020
|
|
9F3R
 | | 13pf E254Q microtubule from recombinant human tubulin decorated with EB3 | | Descriptor: | Detyrosinated tubulin alpha-1B chain, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Estevez-Gallego, J, Blum, T.B, Steinmetz, M.O, Surrey, T. | | Deposit date: | 2024-04-25 | | Release date: | 2025-03-19 | | Method: | ELECTRON MICROSCOPY (4.3 Å) | | Cite: | Hydrolysis-deficient mosaic microtubules as faithful mimics of the GTP cap.
Nat Commun, 16, 2025
|
|
9F3H
 | | Undecorated 13pf mosaic 20%E254Q - 80% E254QN microtubule from recombinant human tubulin | | Descriptor: | Detyrosinated tubulin alpha-1B chain, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Estevez-Gallego, J, Blum, T.B, Steinmetz, M.O, Surrey, T. | | Deposit date: | 2024-04-25 | | Release date: | 2025-03-19 | | Method: | ELECTRON MICROSCOPY (4.3 Å) | | Cite: | Hydrolysis-deficient mosaic microtubules as faithful mimics of the GTP cap.
Nat Commun, 16, 2025
|
|
9F3S
 | | 13pf mosaic 20%E254Q - 80% E254N microtubule from recombinant human tubulin decorated with EB3 | | Descriptor: | Detyrosinated tubulin alpha-1B chain, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Estevez-Gallego, J, Blum, T.B, Steinmetz, M.O, Surrey, T. | | Deposit date: | 2024-04-25 | | Release date: | 2025-03-19 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Hydrolysis-deficient mosaic microtubules as faithful mimics of the GTP cap.
Nat Commun, 16, 2025
|
|
9F3B
 | | Undecorated 13pf E254Q microtubule from recombinant human tubulin | | Descriptor: | Detyrosinated tubulin alpha-1B chain, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Estevez-Gallego, J, Blum, T.B, Steinmetz, M.O, Surrey, T. | | Deposit date: | 2024-04-25 | | Release date: | 2025-03-19 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Hydrolysis-deficient mosaic microtubules as faithful mimics of the GTP cap.
Nat Commun, 16, 2025
|
|
6WVL
 | | Low curvature lateral interaction within a 13-protofilament, Taxol stabilized microtubule | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Debs, G.E, Cha, M, Huehn, A.R, Sindelar, C.V. | | Deposit date: | 2020-05-06 | | Release date: | 2020-05-20 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Dynamic and asymmetric fluctuations in the microtubule wall captured by high-resolution cryoelectron microscopy.
Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
9F6U
 | | cryoEM structure of Asgard tubulin heterodimer AtubA/B with GDP | | Descriptor: | Asgard tubulin A (AtubA) from Candidatus Lokiarchaeum ossiferum, Asgard tubulin B (AtubB) from Candidatus Lokiarchaeum ossiferum, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Wollweber, F, Xu, J, Ponce-Toled, R.I, Rodrigues-Oliveira, T, Malit, J.J.L, Kokhanovska, A, Schleper, C, Pilhofer, M. | | Deposit date: | 2024-05-02 | | Release date: | 2025-04-02 | | Last modified: | 2025-05-14 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Microtubules in Asgard archaea.
Cell, 188, 2025
|
|
9F6T
 | | cryoEM structure of Asgard tubulin heterodimer AtubA/B with GTP | | Descriptor: | Asgard tubulin A (AtubA) from Candidatus Lokiarchaeum ossiferum, Asgard tubulin B (AtubB) from Candidatus Lokiarchaeum ossiferum, GUANOSINE-5'-TRIPHOSPHATE | | Authors: | Wollweber, F, Xu, J, Ponce-Toled, R.I, Rodrigues-Oliveira, T, Malit, J.J.L, Kokhanovska, A, Schleper, C, Pilhofer, M. | | Deposit date: | 2024-05-02 | | Release date: | 2025-04-02 | | Last modified: | 2025-05-14 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Microtubules in Asgard archaea.
Cell, 188, 2025
|
|
9F6V
 | | cryoEM structure of Asgard tubulin heterodimer AtubA/B2 with GTP | | Descriptor: | Asgard tubulin A (AtubA) from Candidatus Lokiarchaeum ossiferum, Asgard tubulin B homolog (AtubB2) from Candidatus Lokiarchaeum ossiferum, GUANOSINE-5'-TRIPHOSPHATE | | Authors: | Wollweber, F, Xu, J, Ponce-Toled, R.I, Rodrigues-Oliveira, T, Malit, J.J.L, Kokhanovska, A, Schleper, C, Pilhofer, M. | | Deposit date: | 2024-05-02 | | Release date: | 2025-04-02 | | Last modified: | 2025-05-14 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Microtubules in Asgard archaea.
Cell, 188, 2025
|
|
