9E1U
 
 | | Snf2h bound nucleosome complex - ClassC1 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA (151-MER), DNA (152-MER), ... | | Authors: | Malik, D, Deshmukh, A.A, Bilokapic, S, Halic, M. | | Deposit date: | 2024-10-21 | | Release date: | 2025-01-22 | | Last modified: | 2025-05-28 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Mechanisms of chromatin remodeling by an Snf2-type ATPase.
Biorxiv, 2025
|
|
9E1R
 | | Snf2h bound nucleosome complex - ClassB4 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA (152-MER), Histone H2A type 1, ... | | Authors: | Malik, D, Deshmukh, A.A, Bilokapic, S, Halic, M. | | Deposit date: | 2024-10-21 | | Release date: | 2025-01-22 | | Last modified: | 2025-05-21 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Snf2h bound nucleosome complex-ClassB4
To Be Published
|
|
9E1W
 | | Snf2h bound nucleosome complex - ClassC3 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA (151-MER), DNA (152-MER), ... | | Authors: | Malik, D, Deshmukh, A.A, Bilokapic, S, Halic, M. | | Deposit date: | 2024-10-21 | | Release date: | 2025-01-22 | | Last modified: | 2025-05-28 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Snf2h bound nucleosome complex-ClassC3
To Be Published
|
|
9E1L
 | | Snf2h bound nucleosome complex - ClassA1 | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, DNA (149-MER), DNA (151-MER), ... | | Authors: | Malik, D, Deshmukh, A.A, Bilokapic, S, Halic, M. | | Deposit date: | 2024-10-21 | | Release date: | 2025-01-22 | | Last modified: | 2025-05-28 | | Method: | ELECTRON MICROSCOPY (3.15 Å) | | Cite: | Snf2h bound nucleosome complex-ClassA1
To Be Published
|
|
9E1M
 | | Snf2h bound nucleosome complex - ClassA2 | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, DNA (149-MER), DNA (151-MER), ... | | Authors: | Malik, D, Deshmukh, A.A, Bilokapic, S, Halic, M. | | Deposit date: | 2024-10-21 | | Release date: | 2025-01-22 | | Last modified: | 2025-05-14 | | Method: | ELECTRON MICROSCOPY (3.25 Å) | | Cite: | Snf2h bound nucleosome complex - ClassA2
To Be Published
|
|
9E1V
 | | Snf2h bound nucleosome complex - ClassC2 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA (151-MER), DNA (152-MER), ... | | Authors: | Malik, D, Deshmukh, A.A, Bilokapic, S, Halic, M. | | Deposit date: | 2024-10-21 | | Release date: | 2025-01-22 | | Last modified: | 2025-05-21 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Snf2h bound nucleosome complex-ClassC2
To Be Published
|
|
5M32
 | | Human 26S proteasome in complex with Oprozomib | | Descriptor: | 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ... | | Authors: | Haselbach, D, Schrader, J, Lambrecht, F, Henneberg, F, Chari, A, Stark, H. | | Deposit date: | 2016-10-14 | | Release date: | 2017-07-05 | | Last modified: | 2025-07-09 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Long-range allosteric regulation of the human 26S proteasome by 20S proteasome-targeting cancer drugs.
Nat Commun, 8, 2017
|
|
8TOF
 | | Rpd3S bound to an H3K36Cme3 modified nucleosome | | Descriptor: | Chromatin modification-related protein EAF3, DNA (176-MER), Histone H2A, ... | | Authors: | Markert, J.W, Vos, S.M, Farnung, L. | | Deposit date: | 2023-08-03 | | Release date: | 2024-01-17 | | Last modified: | 2024-11-06 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Structure of the complete Saccharomyces cerevisiae Rpd3S-nucleosome complex.
Nat Commun, 14, 2023
|
|
8R9U
 | | A soakable crystal form of human CDK7 in complex with AMP-PNP | | Descriptor: | 7-dimethylphosphoryl-3-[2-[[(3~{S})-6,6-dimethylpiperidin-3-yl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]-1~{H}-indole-6-carbonitrile, Cyclin-dependent kinase 7 | | Authors: | Mukherjee, M, Cleasby, A. | | Deposit date: | 2023-11-30 | | Release date: | 2024-05-29 | | Last modified: | 2024-08-21 | | Method: | X-RAY DIFFRACTION (1.937 Å) | | Cite: | Protein engineering enables a soakable crystal form of human CDK7 primed for high-throughput crystallography and structure-based drug design.
Structure, 32, 2024
|
|
8R9S
 | | A soakable crystal form of human CDK7 in complex with AMP-PNP | | Descriptor: | 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, Cyclin-dependent kinase 7, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Mukherjee, M, Cleasby, A. | | Deposit date: | 2023-11-30 | | Release date: | 2024-05-29 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.78 Å) | | Cite: | Protein engineering enables a soakable crystal form of human CDK7 primed for high-throughput crystallography and structure-based drug design.
Structure, 32, 2024
|
|
8R9A
 | | A soakable crystal form of human CDK7 in complex with AMP-PNP | | Descriptor: | (3R,4R)-4-[[[7-[(phenylmethyl)amino]-3-propan-2-yl-pyrazolo[1,5-a]pyrimidin-5-yl]amino]methyl]piperidin-3-ol, Cyclin-dependent kinase 7, DI(HYDROXYETHYL)ETHER | | Authors: | Mukherjee, M, Cleasby, A. | | Deposit date: | 2023-11-30 | | Release date: | 2024-05-29 | | Last modified: | 2024-08-21 | | Method: | X-RAY DIFFRACTION (1.71 Å) | | Cite: | Protein engineering enables a soakable crystal form of human CDK7 primed for high-throughput crystallography and structure-based drug design.
Structure, 32, 2024
|
|
8R9O
 | | A soakable crystal form of human CDK7 in complex with AMP-PNP | | Descriptor: | Cyclin-dependent kinase 7, ~{N}-[(1~{S})-2-(dimethylamino)-1-phenyl-ethyl]-6,6-dimethyl-3-[[4-(propanoylamino)phenyl]carbonylamino]-1,4-dihydropyrrolo[3,4-c]pyrazole-5-carboxamide | | Authors: | Mukherjee, M, Cleasby, A. | | Deposit date: | 2023-11-30 | | Release date: | 2024-05-29 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.22 Å) | | Cite: | Protein engineering enables a soakable crystal form of human CDK7 primed for high-throughput crystallography and structure-based drug design.
Structure, 32, 2024
|
|
8R9B
 | | A soakable crystal form of human CDK7 in complex with AMP-PNP | | Descriptor: | Cyclin-dependent kinase 7, GLYCEROL, MAGNESIUM ION, ... | | Authors: | Mukherjee, M, Cleasby, A. | | Deposit date: | 2023-11-30 | | Release date: | 2024-05-29 | | Last modified: | 2024-08-21 | | Method: | X-RAY DIFFRACTION (2.21 Å) | | Cite: | Protein engineering enables a soakable crystal form of human CDK7 primed for high-throughput crystallography and structure-based drug design.
Structure, 32, 2024
|
|
8R99
 | | A soakable crystal form of human CDK7 in complex with AMP-PNP | | Descriptor: | Cyclin-dependent kinase 7, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | Authors: | Mukherjee, M, Cleasby, A. | | Deposit date: | 2023-11-30 | | Release date: | 2024-05-29 | | Last modified: | 2024-08-21 | | Method: | X-RAY DIFFRACTION (1.81 Å) | | Cite: | Protein engineering enables a soakable crystal form of human CDK7 primed for high-throughput crystallography and structure-based drug design.
Structure, 32, 2024
|
|
9E1P
 | | Snf2h bound nucleosome complex - ClassB2 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA (152-MER), Histone H2A type 1, ... | | Authors: | Malik, D, Deshmukh, A.A, Bilokapic, S, Halic, M. | | Deposit date: | 2024-10-21 | | Release date: | 2025-01-22 | | Last modified: | 2025-05-28 | | Method: | ELECTRON MICROSCOPY (3.25 Å) | | Cite: | Snf2h bound nucleosome complex-ClassB2
To Be Published
|
|
9E1Q
 | | Snf2h bound nucleosome complex - ClassB3 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA (152-MER), Histone H2A type 1, ... | | Authors: | Malik, D, Deshmukh, A.A, Bilokapic, S, Halic, M. | | Deposit date: | 2024-10-21 | | Release date: | 2025-01-22 | | Last modified: | 2025-06-04 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Snf2h bound nucleosome complex-ClassB3
To Be Published
|
|
9E1O
 | | Snf2h bound nucleosome complex - ClassB1 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA (148-MER), DNA (150-MER), ... | | Authors: | Malik, D, Deshmukh, A.A, Bilokapic, S, Halic, M. | | Deposit date: | 2024-10-21 | | Release date: | 2025-01-22 | | Last modified: | 2025-05-28 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Snf2h bound nucleosome complex-ClassB1
To Be Published
|
|
9E1N
 | | Snf2h bound nucleosome complex-ClassA3 | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, DNA (149-MER), DNA (151-MER), ... | | Authors: | Malik, D, Deshmukh, A.A, Bilokapic, S, Halic, M. | | Deposit date: | 2024-10-21 | | Release date: | 2025-01-22 | | Last modified: | 2025-05-28 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Snf2h bound nucleosome complex-ClassA3
To Be Published
|
|
7Z8R
 | | CAND1-CUL1-RBX1 | | Descriptor: | Cullin-1, Cullin-associated NEDD8-dissociated protein 1, E3 ubiquitin-protein ligase RBX1, ... | | Authors: | Baek, K, Schulman, B.A. | | Deposit date: | 2022-03-18 | | Release date: | 2023-04-19 | | Last modified: | 2025-07-09 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Systemwide disassembly and assembly of SCF ubiquitin ligase complexes.
Cell, 186, 2023
|
|
5J9Q
 | | Crystal structure of the NuA4 core complex | | Descriptor: | Chromatin modification-related protein EAF6, Chromatin modification-related protein YNG2, Enhancer of polycomb-like protein 1, ... | | Authors: | Chen, Z.C, Xu, P. | | Deposit date: | 2016-04-11 | | Release date: | 2016-10-26 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (3.25 Å) | | Cite: | The NuA4 Core Complex Acetylates Nucleosomal Histone H4 through a Double Recognition Mechanism
Mol.Cell, 63, 2016
|
|
6WJN
 | |
2I40
 | | Cdk2/Cyclin A complexed with a thiophene carboxamide inhibitor | | Descriptor: | 5-[5,6-BIS(METHYLOXY)-1H-BENZIMIDAZOL-1-YL]-3-{[1-(2-CHLOROPHENYL)ETHYL]OXY}-2-THIOPHENECARBOXAMIDE, Cell division protein kinase 2, Cyclin-A2 | | Authors: | Shewchuk, L.M. | | Deposit date: | 2006-08-21 | | Release date: | 2006-10-10 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | 5-(1H-Benzimidazol-1-yl)-3-alkoxy-2-thiophenecarbonitriles as potent, selective, inhibitors of IKK-epsilon kinase
Bioorg.Med.Chem.Lett., 16, 2006
|
|
8HZC
 | |
8HZB
 | |
5JQ5
 | | Crystal structure of CDK2 in complex with inhibitor ICEC0942 | | Descriptor: | (3R,4R)-4-[[[7-[(phenylmethyl)amino]-3-propan-2-yl-pyrazolo[1,5-a]pyrimidin-5-yl]amino]methyl]piperidin-3-ol, ACETATE ION, Cyclin-dependent kinase 2 | | Authors: | Hazel, P, Freemont, P.S. | | Deposit date: | 2016-05-04 | | Release date: | 2017-02-08 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.94 Å) | | Cite: | Inhibitor Selectivity for Cyclin-Dependent Kinase 7: A Structural, Thermodynamic, and Modelling Study.
ChemMedChem, 12, 2017
|
|
