PDB: 8697 resultsInfo pagesStatus searchChemie searchBIRD

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6F5O	A mechanism for the activation of the influenza virus transcriptase Descriptor: 3' promoter vRNA, 5' promoter vRNA, Polymerase acidic protein, ... Authors: Serna Martin, I, Grimes, J.M. Deposit date: 2017-12-02 Release date: 2018-06-27 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (9.8 Å) Cite: A Mechanism for the Activation of the Influenza Virus Transcriptase. Mol. Cell, 70, 2018
6YYS	Structure of Mycobacterium smegmatis HelD protein in complex with RNA polymerase core - State II, primary channel engaged and active site interfering Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Kouba, T, Koval, T, Krasny, L, Dohnalek, J. Deposit date: 2020-05-05 Release date: 2020-11-04 Last modified: 2024-07-10 Method: ELECTRON MICROSCOPY (3.08 Å) Cite: Mycobacterial HelD is a nucleic acids-clearing factor for RNA polymerase. Nat Commun, 11, 2020
2F8E	Foot and Mouth Disease Virus RNA-dependent RNA polymerase in complex with uridylylated VPg protein Descriptor: MAGNESIUM ION, MANGANESE (II) ION, RNA-dependent RNA polymerase, ... Authors: Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N. Deposit date: 2005-12-02 Release date: 2006-03-28 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.9 Å) Cite: The structure of a protein primer-polymerase complex in the initiation of genome replication Embo J., 25, 2006
1YUY	HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE GENOTYPE 2a Descriptor: RNA-Dependent RNA polymerase, SULFATE ION Authors: Biswal, B.K, Cherney, M.M, Wang, M, Chan, L, Yannopoulos, C.G, Bilimoria, D, Nicolas, O, Bedard, J, James, M.N.G. Deposit date: 2005-02-14 Release date: 2005-03-22 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal structures of the RNA dependent RNA polymerase genotype 2a of hepatitis C virus reveal two conformations and suggest mechanisms of inhibition by non-nucleoside inhibitors. J.Biol.Chem., 280, 2005
3P9Y	Crystal structure of the Drosophila melanogaster Ssu72-pCTD complex Descriptor: CG14216, IMIDAZOLE, TETRAETHYLENE GLYCOL, ... Authors: Werner-Allen, J.W, Zhou, P. Deposit date: 2010-10-18 Release date: 2010-12-15 Last modified: 2016-08-17 Method: X-RAY DIFFRACTION (2.1 Å) Cite: cis-Proline-mediated Ser(P)5 Dephosphorylation by the RNA Polymerase II C-terminal Domain Phosphatase Ssu72. J.Biol.Chem., 286, 2011
7F0S	A crystal structure of alphavirus nonstructural protein 4 (nsP4) reveals an intrinsically 1dynamic RNA-dependent RNA polymerase Descriptor: RNA-directed RNA polymerase nsP4 Authors: Tan, Y.B, Luo, D. Deposit date: 2021-06-06 Release date: 2022-02-16 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Crystal structures of alphavirus nonstructural protein 4 (nsP4) reveal an intrinsically dynamic RNA-dependent RNA polymerase fold. Nucleic Acids Res., 50, 2022
3TJ1	Crystal Structure of RNA Polymerase I Transcription Initiation Factor Rrn3 Descriptor: RNA polymerase I-specific transcription initiation factor RRN3 Authors: Blattner, C, Jennebach, S, Herzog, F, Mayer, A, Cheung, A.C.M, Witte, G, Lorenzen, K, Hopfner, K.-P, Heck, A.J.R, Aebersold, R, Cramer, P. Deposit date: 2011-08-23 Release date: 2011-09-28 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Molecular basis of Rrn3-regulated RNA polymerase I initiation and cell growth. Genes Dev., 25, 2011
6XKB	Crystal structure of SR-related and CTD-associated factor 4(SCAF4-CID)with peptide S2,S5p-CTD Descriptor: S2,S5p-CTD peptide, SR-related and CTD-associated factor 4, UNKNOWN ATOM OR ION Authors: Zhou, M.Q, Dong, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) Deposit date: 2020-06-26 Release date: 2021-01-20 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structural basis for the recognition of the S2, S5-phosphorylated RNA polymerase II CTD by the mRNA anti-terminator protein hSCAF4. Febs Lett., 596, 2022
8W8E	human co-transcriptional RNA capping enzyme RNGTT Descriptor: DNA (36-MER), DNA (45-MER), DNA-directed RNA polymerase II subunit E, ... Authors: Li, Y, Wang, Q, Xu, Y, Li, Z. Deposit date: 2023-09-02 Release date: 2024-04-10 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Structures of co-transcriptional RNA capping enzymes on paused transcription complex. Nat Commun, 15, 2024
8W8F	human co-transcriptional RNA capping enzyme RNGTT-CMTR1 Descriptor: Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1, DNA (36-MER), DNA (45-MER), ... Authors: Li, Y, Wang, Q, Xu, Y, Li, Z. Deposit date: 2023-09-02 Release date: 2024-04-10 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (4 Å) Cite: Structures of co-transcriptional RNA capping enzymes on paused transcription complex. Nat Commun, 15, 2024
2RF4	Crystal structure of the RNA Polymerase I subcomplex A14/43 Descriptor: DNA-directed RNA polymerase I subunit RPA4 Authors: Geiger, S.R, Kuhn, C.D, Cramer, P. Deposit date: 2007-09-28 Release date: 2008-01-15 Last modified: 2017-10-25 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Functional architecture of RNA polymerase I. Cell(Cambridge,Mass.), 131, 2007
6GMH	Structure of activated transcription complex Pol II-DSIF-PAF-SPT6 Descriptor: CDC73, CTR9,RNA polymerase-associated protein CTR9 homolog,RNA polymerase-associated protein CTR9 homolog, DNA-directed RNA polymerase II subunit RPB9, ... Authors: Vos, S.M, Farnung, L, Boehing, M, Linden, A, Wigge, C, Urlaub, H, Cramer, P. Deposit date: 2018-05-26 Release date: 2018-08-22 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structure of activated transcription complex Pol II-DSIF-PAF-SPT6. Nature, 560, 2018
6TED	Structure of complete, activated transcription complex Pol II-DSIF-PAF-SPT6 uncovers allosteric elongation activation by RTF1 Descriptor: DNA (37-MER), DNA-directed RNA polymerase II subunit RPB9, DNA-directed RNA polymerase subunit, ... Authors: Vos, S.M, Farnung, L, Cramer, P. Deposit date: 2019-11-11 Release date: 2020-07-22 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structure of complete Pol II-DSIF-PAF-SPT6 transcription complex reveals RTF1 allosteric activation. Nat.Struct.Mol.Biol., 27, 2020
8JCH	Cryo-EM structure of yeast Rat1-bound Pol II pre-termination transcription complex 1 (Pol II Rat1-PTTC1) Descriptor: 5'-3' exoribonuclease 2, DNA (38-MER), DNA-directed RNA polymerase II subunit RPB1, ... Authors: Zeng, Y, Zhang, Y. Deposit date: 2023-05-11 Release date: 2024-01-31 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Structural basis of exoribonuclease-mediated mRNA transcription termination. Nature, 628, 2024
8K5P	Cryo-EM structure of yeast Rat1-bound Pol II pre-termination transcription complex 2 (Pol II Rat1-PTTC2) Descriptor: 5'-3' exoribonuclease 2, DNA (38-MER), DNA-directed RNA polymerase II subunit RPB1, ... Authors: Zeng, Y, Zhang, Y. Deposit date: 2023-07-23 Release date: 2024-01-31 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Structural basis of exoribonuclease-mediated mRNA transcription termination. Nature, 628, 2024
7ZSB	Yeast RNA polymerase II transcription pre-initiation complex with the +1 nucleosome and NTP, complex C Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... Authors: Wang, H, Cramer, P. Deposit date: 2022-05-06 Release date: 2022-11-16 Last modified: 2023-03-01 Method: ELECTRON MICROSCOPY (6.6 Å) Cite: Structures of transcription preinitiation complex engaged with the +1 nucleosome. Nat.Struct.Mol.Biol., 30, 2023
7ZSA	Yeast RNA polymerase II transcription pre-initiation complex with the +1 nucleosome and NTP (complex B) Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... Authors: Wang, H, Cramer, P. Deposit date: 2022-05-06 Release date: 2022-11-16 Last modified: 2023-03-01 Method: ELECTRON MICROSCOPY (4 Å) Cite: Structures of transcription preinitiation complex engaged with the +1 nucleosome. Nat.Struct.Mol.Biol., 30, 2023
7ZS9	Yeast RNA polymerase II transcription pre-initiation complex with the +1 nucleosome (complex A) Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... Authors: Wang, H, Cramer, P. Deposit date: 2022-05-06 Release date: 2022-11-16 Last modified: 2023-03-01 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structures of transcription preinitiation complex engaged with the +1 nucleosome. Nat.Struct.Mol.Biol., 30, 2023
6GML	Structure of paused transcription complex Pol II-DSIF-NELF Descriptor: DNA-directed RNA polymerase II subunit RPB9, DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... Authors: Vos, S.M, Farnung, L, Urlaub, H, Cramer, P. Deposit date: 2018-05-27 Release date: 2018-09-05 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Structure of paused transcription complex Pol II-DSIF-NELF. Nature, 560, 2018
8TVP	Cryo-EM structure of CPD-stalled Pol II in complex with Rad26 (open state) Descriptor: DNA (NTS), DNA (TS), DNA repair and recombination protein RAD26, ... Authors: Sarsam, R.D, Lahiri, I, Leschziner, A.E. Deposit date: 2023-08-18 Release date: 2024-01-24 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair. Proc.Natl.Acad.Sci.USA, 121, 2024
8TVV	Cryo-EM structure of backtracked Pol II Descriptor: DNA (NTS), DNA (TS), DNA-directed RNA polymerase II subunit RPB1, ... Authors: Sarsam, R.D, Lahiri, I, Leschziner, A.E. Deposit date: 2023-08-18 Release date: 2024-01-24 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair. Proc.Natl.Acad.Sci.USA, 121, 2024
8TVX	Cryo-EM structure of CPD-stalled Pol II (Conformation 2) Descriptor: DNA (NTS), DNA (TS), DNA-directed RNA polymerase II subunit RPB1, ... Authors: Sarsam, R.D, Lahiri, I, Leschziner, A.E. Deposit date: 2023-08-18 Release date: 2024-01-24 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair. Proc.Natl.Acad.Sci.USA, 121, 2024
8TVW	Cryo-EM structure of CPD-stalled Pol II (conformation 1) Descriptor: DNA (NTS), DNA (TS), DNA-directed RNA polymerase II subunit RPB1, ... Authors: Sarsam, R.D, Lahiri, I, Leschziner, A.E. Deposit date: 2023-08-18 Release date: 2024-01-24 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair. Proc.Natl.Acad.Sci.USA, 121, 2024
8TUG	Cryo-EM structure of CPD-stalled Pol II in complex with Rad26 (engaged state) Descriptor: DNA (NTS), DNA (TS), DNA repair and recombination protein RAD26, ... Authors: Sarsam, R.D, Lahiri, I, Leschziner, A.E. Deposit date: 2023-08-16 Release date: 2024-01-24 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair. Proc.Natl.Acad.Sci.USA, 121, 2024
8TVS	Cryo-EM structure of backtracked Pol II in complex with Rad26 Descriptor: DNA (NTS), DNA (TS), DNA repair and recombination protein RAD26, ... Authors: Sarsam, R.D, Lahiri, I, Leschziner, A.E. Deposit date: 2023-08-18 Release date: 2024-01-24 Method: ELECTRON MICROSCOPY (4.4 Å) Cite: Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair. Proc.Natl.Acad.Sci.USA, 121, 2024

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