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8VDN
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BU of 8vdn by Molmil
DNA Ligase 1 with nick dG:C
Descriptor: ADENOSINE MONOPHOSPHATE, DNA ligase 1, Downstream Oligo, ...
Authors:KanalElamparithi, B, Gulkis, M, Caglayan, M.
Deposit date:2023-12-16
Release date:2024-05-22
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Structures of LIG1 provide a mechanistic basis for understanding a lack of sugar discrimination against a ribonucleotide at the 3'-end of nick DNA.
J.Biol.Chem., 300, 2024
8XGT
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BU of 8xgt by Molmil
Crystal structure of human secretory glutaminyl cyclase in complex with (Z)-3-((1H-benzo[d]imidazol-5-yl)methylene)-4-hydroxyindolin-2-one
Descriptor: (3~{Z})-3-(1~{H}-benzimidazol-5-ylmethylidene)-4-oxidanyl-1~{H}-indol-2-one, Glutaminyl-peptide cyclotransferase, ZINC ION
Authors:Li, G.-B, Wang, X.-Y.
Deposit date:2023-12-15
Release date:2024-06-12
Last modified:2024-06-26
Method:X-RAY DIFFRACTION (2.813 Å)
Cite:X-ray Structure-Guided Discovery of a Potent Benzimidazole Glutaminyl Cyclase Inhibitor That Shows Activity in a Parkinson's Disease Mouse Model.
J.Med.Chem., 67, 2024
8XGB
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BU of 8xgb by Molmil
Crystal structure of human secretory glutaminyl cyclase in complex with (S)-1-(1H-benzo[d]imidazol-5-yl)-5-(4-propoxyphenyl)imidazolidin-2-one
Descriptor: (5~{S})-1-(3~{H}-benzimidazol-5-yl)-5-(4-propoxyphenyl)imidazolidin-2-one, Glutaminyl-peptide cyclotransferase, ZINC ION
Authors:Li, G.-B, Wang, X.-Y.
Deposit date:2023-12-15
Release date:2024-06-12
Last modified:2024-06-26
Method:X-RAY DIFFRACTION (3.24 Å)
Cite:X-ray Structure-Guided Discovery of a Potent Benzimidazole Glutaminyl Cyclase Inhibitor That Shows Activity in a Parkinson's Disease Mouse Model.
J.Med.Chem., 67, 2024
8RHI
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BU of 8rhi by Molmil
Lytic Transglycosylase MltD of Pseudomonas aeruginosa in a ternary complex bound to Bulgecin A and chito-tetraose
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-O-(4-O-SULFONYL-N-ACETYLGLUCOSAMININYL)-5-METHYLHYDROXY-L-PROLINE-TAURINE, ...
Authors:Miguel-Ruano, V, Hermoso, J.A.
Deposit date:2023-12-15
Release date:2024-04-17
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structural characterization of lytic transglycosylase MltD of Pseudomonas aeruginosa, a target for the natural product bulgecin A.
Int.J.Biol.Macromol., 267, 2024
8RHE
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BU of 8rhe by Molmil
Lytic Transglycosylase MltD of Pseudomonas aeruginosa bound to the Natural Product Bulgecin A
Descriptor: 4-O-(4-O-SULFONYL-N-ACETYLGLUCOSAMININYL)-5-METHYLHYDROXY-L-PROLINE-TAURINE, LysM peptidoglycan-binding domain-containing protein, ZINC ION
Authors:Miguel-Ruano, V, Hermoso, J.A.
Deposit date:2023-12-15
Release date:2024-04-17
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural characterization of lytic transglycosylase MltD of Pseudomonas aeruginosa, a target for the natural product bulgecin A.
Int.J.Biol.Macromol., 267, 2024
8RHF
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BU of 8rhf by Molmil
Lytic Transglycosylase MltD of Pseudomonas aeruginosa bound to the Natural Product Bulgecin A, with two LysM domains
Descriptor: 4-O-(4-O-SULFONYL-N-ACETYLGLUCOSAMININYL)-5-METHYLHYDROXY-L-PROLINE-TAURINE, DI(HYDROXYETHYL)ETHER, LysM peptidoglycan-binding domain-containing protein, ...
Authors:Miguel-Ruano, V, Hermoso, J.A.
Deposit date:2023-12-15
Release date:2024-04-17
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural characterization of lytic transglycosylase MltD of Pseudomonas aeruginosa, a target for the natural product bulgecin A.
Int.J.Biol.Macromol., 267, 2024
8RH6
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BU of 8rh6 by Molmil
Crystal structure of HLA-A*11:01 in complex with SVLNDILSRL, an 10-mer epitope from SARS-CoV-2 Spike (S975-984)
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ...
Authors:Ahn, Y.M, Maddumage, J.C, Szeto, C, Gras, S.
Deposit date:2023-12-15
Release date:2024-05-15
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (3.32 Å)
Cite:The impact of SARS-CoV-2 spike mutation on peptide presentation is HLA allomorph-specific.
Curr Res Struct Biol, 7, 2024
8XGC
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BU of 8xgc by Molmil
Structure of yeast replisome associated with FACT and histone hexamer, Composite map
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, Chromosome segregation in meiosis protein 3, ...
Authors:Li, N, Gao, Y, Yu, D, Gao, N, Zhai, Y.
Deposit date:2023-12-15
Release date:2024-02-14
Last modified:2024-04-10
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Parental histone transfer caught at the replication fork.
Nature, 627, 2024
8RGQ
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BU of 8rgq by Molmil
Open Complex I from murine liver
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Vercellino, I, Sazanov, L.A.
Deposit date:2023-12-14
Release date:2024-04-24
Method:ELECTRON MICROSCOPY (3 Å)
Cite:SCAF1 drives the compositional diversity of mammalian respirasomes.
Nat.Struct.Mol.Biol., 2024
8RGP
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BU of 8rgp by Molmil
Closed Complex I from murine brain
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Vercellino, I, Sazanov, L.A.
Deposit date:2023-12-14
Release date:2024-04-24
Method:ELECTRON MICROSCOPY (3 Å)
Cite:SCAF1 drives the compositional diversity of mammalian respirasomes.
Nat.Struct.Mol.Biol., 2024
8RGR
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BU of 8rgr by Molmil
Closed Complex I from murine liver
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Vercellino, I, Sazanov, L.A.
Deposit date:2023-12-14
Release date:2024-04-24
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:SCAF1 drives the compositional diversity of mammalian respirasomes.
Nat.Struct.Mol.Biol., 2024
8RGT
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BU of 8rgt by Molmil
Open Complex I from murine brain
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Vercellino, I, Sazanov, L.A.
Deposit date:2023-12-14
Release date:2024-04-24
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:SCAF1 drives the compositional diversity of mammalian respirasomes.
Nat.Struct.Mol.Biol., 2024
8VCI
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BU of 8vci by Molmil
SARS-CoV-2 Frameshift Stimulatory Element with Upstream Multibranch Loop
Descriptor: Frameshift Stimulatory Element with Upstream Multi-branch Loop
Authors:Peterson, J.M, Becker, S.T, O'Leary, C.A, Juneja, P, Yang, Y, Moss, W.N.
Deposit date:2023-12-14
Release date:2024-01-17
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (6.1 Å)
Cite:Structure of the SARS-CoV-2 Frameshift Stimulatory Element with an Upstream Multibranch Loop.
Biochemistry, 63, 2024
8RH3
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BU of 8rh3 by Molmil
Nucleoside 2'deoxyribosyltransferase from Chroococcidiopsis thermalis PCC 7203 WT bound to Gemcitabine
Descriptor: (2~{R},3~{R})-4,4-bis(fluoranyl)-2-(hydroxymethyl)oxolan-3-ol, Nucleoside 2-deoxyribosyltransferase
Authors:Tang, P, Harding, C.J, Czekster, C.M.
Deposit date:2023-12-14
Release date:2024-02-21
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Snapshots of the Reaction Coordinate of a Thermophilic 2'-Deoxyribonucleoside/ribonucleoside Transferase.
Acs Catalysis, 14, 2024
8RGL
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BU of 8rgl by Molmil
Structure of Human Serum Albumin in complex with Aristolochic Acid I at 1.9 A resolution - Optimized
Descriptor: 1,2-ETHANEDIOL, 8-methoxy-6-nitro-naphtho[1,2-e][1,3]benzodioxole-5-carboxylic acid, MYRISTIC ACID, ...
Authors:Pomyalov, S, Sidorenko, V.S, Grollman, A.P, Shoham, G.
Deposit date:2023-12-13
Release date:2024-06-26
Last modified:2024-07-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and mechanistic insights into the transport of aristolochic acids and their active metabolites by human serum albumin.
J.Biol.Chem., 300, 2024
8RGK
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BU of 8rgk by Molmil
Structure of Human Serum Albumin in complex with Aristolochic Acid at 1.9 A resolution
Descriptor: 1,2-ETHANEDIOL, 8-methoxy-6-nitro-naphtho[1,2-e][1,3]benzodioxole-5-carboxylic acid, MYRISTIC ACID, ...
Authors:Pomyalov, S, Sidorenko, V.S, Grollman, A.P, Shoham, G.
Deposit date:2023-12-13
Release date:2024-06-26
Last modified:2024-07-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and mechanistic insights into the transport of aristolochic acids and their active metabolites by human serum albumin.
J.Biol.Chem., 300, 2024
8VC5
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BU of 8vc5 by Molmil
Crystal structure of glutamyl-tRNA synthetase GluRS from Pseudomonas aeruginosa (Zinc bound)
Descriptor: CITRATE ANION, GLYCEROL, Glutamate--tRNA ligase, ...
Authors:Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2023-12-13
Release date:2023-12-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of glutamyl-tRNA synthetase GluRS from Pseudomonas aeruginosa (Zinc bound)
To be published
8XEG
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BU of 8xeg by Molmil
Cryo-EM structure of Adeno-associated Virus 9P31 in 1.76 angstrom.
Descriptor: Capsid protein VP1
Authors:Zhang, R, Liu, Y, Lou, Z.
Deposit date:2023-12-12
Release date:2024-01-24
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (1.76 Å)
Cite:Structural basis of the recognition of adeno-associated virus by the neurological system-related receptor carbonic anhydrase IV.
Plos Pathog., 20, 2024
8REF
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BU of 8ref by Molmil
Crystal structure of HLA B*13:01 in complex with SVLNDILARL, an 10-mer epitope from SARS-CoV-2 Spike (S975-984)
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ...
Authors:Ahn, Y.M, Maddumage, J.C, Szeto, C, Gras, S.
Deposit date:2023-12-11
Release date:2024-05-15
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The impact of SARS-CoV-2 spike mutation on peptide presentation is HLA allomorph-specific.
Curr Res Struct Biol, 7, 2024
8VAR
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BU of 8var by Molmil
Structure of the E. coli clamp loader bound to the beta clamp in a Closed-DNA2 conformation
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ...
Authors:Landeck, J.T, Kelch, B.A.
Deposit date:2023-12-11
Release date:2024-03-27
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication.
J.Biol.Chem., 300, 2024
8VAL
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BU of 8val by Molmil
Structure of the E. coli clamp loader bound to the beta clamp in a Open-DNAp/t conformation
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ...
Authors:Landeck, J.T, Kelch, B.A.
Deposit date:2023-12-11
Release date:2024-03-27
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication.
J.Biol.Chem., 300, 2024
8VAQ
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BU of 8vaq by Molmil
Structure of the E. coli clamp loader bound to the beta clamp in a Closed-DNA1 conformation
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ...
Authors:Landeck, J.T, Kelch, B.A.
Deposit date:2023-12-11
Release date:2024-03-27
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication.
J.Biol.Chem., 300, 2024
8VAP
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BU of 8vap by Molmil
Structure of the E. coli clamp loader bound to the beta clamp in a Fully-Open conformation
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ...
Authors:Landeck, J.T, Kelch, B.A.
Deposit date:2023-12-11
Release date:2024-03-27
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication.
J.Biol.Chem., 300, 2024
8VAM
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BU of 8vam by Molmil
Structure of the E. coli clamp loader bound to the beta clamp in a Semi-Open conformation
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ...
Authors:Landeck, J.T, Kelch, B.A.
Deposit date:2023-12-11
Release date:2024-03-27
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication.
J.Biol.Chem., 300, 2024
8VAS
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BU of 8vas by Molmil
Structure of the E. coli clamp loader bound to the beta clamp in an Altered-Collar conformation
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ...
Authors:Landeck, J.T, Kelch, B.A.
Deposit date:2023-12-11
Release date:2024-03-27
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication.
J.Biol.Chem., 300, 2024

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数据于2024-07-10公开中

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