9G2A
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![BU of 9g2a by Molmil](/molmil-images/mine/9g2a) | Staphylococcus aureus MazF in complex with nanobody 4 | Descriptor: | 3[N-MORPHOLINO]PROPANE SULFONIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Endoribonuclease MazF, ... | Authors: | Prolic-Kalinsek, M, Zorzini, V, Haesaerts, S, Loris, R. | Deposit date: | 2024-07-10 | Release date: | 2024-07-17 | Last modified: | 2024-07-24 | Method: | X-RAY DIFFRACTION (2.046594 Å) | Cite: | Staphylococcus aureus MazF in complex with nanobody 4. To Be Published
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9G1Y
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9G2G
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![BU of 9g2g by Molmil](/molmil-images/mine/9g2g) | Staphylococcus aureus MazF in complex with nanobody 5 | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Endoribonuclease MazF, Nanobody 5 | Authors: | Prolic-Kalinsek, M, Zorzini, V, Haesaerts, S, Loris, R. | Deposit date: | 2024-07-10 | Release date: | 2024-07-24 | Method: | X-RAY DIFFRACTION (1.80048239 Å) | Cite: | Nanobody-mediated activation and inhibition of Staphylococcus aureus MazF To Be Published
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9CK3
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![BU of 9ck3 by Molmil](/molmil-images/mine/9ck3) | Cryo-EM structure of in-vitro alpha-synuclein fibril | Descriptor: | Alpha-synuclein | Authors: | Sanchez, J.C, Borcik, C.G, Tonelli, M, Sibert, B, Rienstra, C.M, Wright, E.R. | Deposit date: | 2024-07-08 | Release date: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (2.04 Å) | Cite: | Multimodal High-Resolution Structure Determination Of Alpha-Synuclein Fibrils To Be Published
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9CJ0
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![BU of 9cj0 by Molmil](/molmil-images/mine/9cj0) | |
9FYP
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![BU of 9fyp by Molmil](/molmil-images/mine/9fyp) | Cryo EM structure of the type 3B polymorph of alpha-synuclein at low pH. | Descriptor: | Alpha-synuclein, CHLORIDE ION | Authors: | Frey, L, Qureshi, B.M, Kwiatkowski, W, Rhyner, D, Greenwald, J, Riek, R. | Deposit date: | 2024-07-03 | Release date: | 2024-07-17 | Last modified: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (2.23 Å) | Cite: | On the pH-dependence of alpha-synuclein amyloid polymorphism and the role of secondary nucleation in seed-based amyloid propagation. Elife, 12, 2024
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9FXI
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![BU of 9fxi by Molmil](/molmil-images/mine/9fxi) | Crystal structure of cobalt(II)-substituted double mutant Y115E Y117E human Glutaminyl Cyclase in complex with SEN177 | Descriptor: | 2-fluoranyl-5-[2-[4-(4-methyl-1,2,4-triazol-3-yl)piperidin-1-yl]pyridin-3-yl]pyridine, COBALT (II) ION, Glutaminyl-peptide cyclotransferase, ... | Authors: | Tassone, G, Pozzi, C, Mangani, S. | Deposit date: | 2024-07-01 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (3.06 Å) | Cite: | Metal Ion Binding to Human Glutaminyl Cyclase: A Structural Perspective. Int J Mol Sci, 25, 2024
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9FXJ
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![BU of 9fxj by Molmil](/molmil-images/mine/9fxj) | Crystal structure of cobalt(II)-substituted double mutant Y115E Y117E human Glutaminyl Cyclase in complex with PBD-150 | Descriptor: | 1-(3,4-dimethoxyphenyl)-3-[3-(1H-imidazol-1-yl)propyl]thiourea, COBALT (II) ION, Glutaminyl-peptide cyclotransferase, ... | Authors: | Tassone, G, Pozzi, C, Mangani, S. | Deposit date: | 2024-07-01 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (3.06 Å) | Cite: | Metal Ion Binding to Human Glutaminyl Cyclase: A Structural Perspective. Int J Mol Sci, 25, 2024
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9FXG
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![BU of 9fxg by Molmil](/molmil-images/mine/9fxg) | Crystal structure of double mutant Y115E Y117E human Glutaminyl Cyclase in apo-state | Descriptor: | 1,2-ETHANEDIOL, Glutaminyl-peptide cyclotransferase, SULFATE ION | Authors: | Tassone, G, Pozzi, C, Mangani, S. | Deposit date: | 2024-07-01 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Metal Ion Binding to Human Glutaminyl Cyclase: A Structural Perspective. Int J Mol Sci, 25, 2024
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9FXH
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![BU of 9fxh by Molmil](/molmil-images/mine/9fxh) | Crystal structure of cobalt(II)-substituted double mutant Y115E Y117E human Glutaminyl Cyclase | Descriptor: | COBALT (II) ION, GLYCEROL, Glutaminyl-peptide cyclotransferase, ... | Authors: | Tassone, G, Pozzi, C, Mangani, S. | Deposit date: | 2024-07-01 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Metal Ion Binding to Human Glutaminyl Cyclase: A Structural Perspective. Int J Mol Sci, 25, 2024
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9FWG
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![BU of 9fwg by Molmil](/molmil-images/mine/9fwg) | LSD1/CoREST bound to bomedemstat | Descriptor: | Bomedemstat FAD adduct, Lysine-specific histone demethylase 1A, REST corepressor 1 | Authors: | Speranzini, V, Mattevi, A. | Deposit date: | 2024-06-30 | Release date: | 2024-07-10 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Characterization of structural, biochemical, pharmacokinetic, and pharmacodynamic properties of the LSD1 inhibitor bomedemstat in preclinical models. Prostate, 84, 2024
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9CEU
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![BU of 9ceu by Molmil](/molmil-images/mine/9ceu) | Spizellomyces punctatus Fanzor (SpuFz) State 1 | Descriptor: | DNA (5'-D(P*CP*CP*TP*AP*TP*AP*GP*AP*TP*AP*TP*GP*CP*CP*CP*GP*GP*GP*TP*AP*CP*CP*G)-3'), DNA (5'-D(P*CP*GP*GP*TP*AP*CP*CP*CP*GP*GP*GP*CP*AP*TP*A)-3'), Maltose/maltodextrin-binding periplasmic protein, ... | Authors: | Xu, P, Saito, M, Zhang, F. | Deposit date: | 2024-06-27 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.29 Å) | Cite: | Structural insights into the diversity and DNA cleavage mechanism of Fanzor. Cell, 2024
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9CET
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![BU of 9cet by Molmil](/molmil-images/mine/9cet) | Guillardia theta Fanzor (GtFz) State 3 | Descriptor: | DNA (28-MER), DNA (5'-D(P*AP*TP*GP*AP*CP*TP*TP*CP*TP*CP*TP*TP*AP*AP*AP*GP*GP*CP*CP*CP*CP*GP*GP*G)-3'), Maltose/maltodextrin-binding periplasmic protein, ... | Authors: | Xu, P, Saito, M, Zhang, F. | Deposit date: | 2024-06-27 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural insights into the diversity and DNA cleavage mechanism of Fanzor. Cell, 2024
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9CF1
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![BU of 9cf1 by Molmil](/molmil-images/mine/9cf1) | Parasitella parasitica Fanzor (PpFz) State 2 | Descriptor: | DNA (5'-D(P*AP*CP*CP*CP*GP*GP*GP*AP*TP*AP*A)-3'), DNA (5'-D(P*GP*CP*TP*GP*GP*AP*TP*GP*TP*TP*TP*AP*TP*CP*CP*CP*GP*GP*GP*T)-3'), DNA/RNA (51-MER), ... | Authors: | Xu, P, Saito, M, Zhang, F. | Deposit date: | 2024-06-27 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.52 Å) | Cite: | Structural insights into the diversity and DNA cleavage mechanism of Fanzor. Cell, 2024
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9CF0
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![BU of 9cf0 by Molmil](/molmil-images/mine/9cf0) | Parasitella parasitica Fanzor (PpFz) State 1 | Descriptor: | DNA (5'-D(P*AP*CP*CP*CP*GP*GP*GP*AP*TP*AP*A)-3'), DNA (5'-D(P*TP*GP*TP*TP*TP*AP*TP*CP*CP*CP*GP*GP*GP*T)-3'), DNA/RNA (54-MER), ... | Authors: | Xu, P, Saito, M, Zhang, F. | Deposit date: | 2024-06-27 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.47 Å) | Cite: | Structural insights into the diversity and DNA cleavage mechanism of Fanzor. Cell, 2024
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9CER
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![BU of 9cer by Molmil](/molmil-images/mine/9cer) | Guillardia theta Fanzor (GtFz) State 1 | Descriptor: | Maltose/maltodextrin-binding periplasmic protein, Guillardia theta Fanzor1 chimera, RNA (142-MER) | Authors: | Xu, P, Saito, M, Zhang, F. | Deposit date: | 2024-06-27 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | Structural insights into the diversity and DNA cleavage mechanism of Fanzor. Cell, 2024
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9CES
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![BU of 9ces by Molmil](/molmil-images/mine/9ces) | Guillardia theta Fanzor (GtFz) State 2 | Descriptor: | DNA (5'-D(P*AP*TP*GP*AP*CP*TP*TP*CP*TP*CP*TP*TP*AP*AP*AP*GP*GP*CP*CP*CP*CP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*GP*GP*GP*GP*CP*CP*TP*TP*TP*AP*AP*G)-3'), Maltose/maltodextrin-binding periplasmic protein, ... | Authors: | Xu, P, Saito, M, Zhang, F. | Deposit date: | 2024-06-27 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.28 Å) | Cite: | Structural insights into the diversity and DNA cleavage mechanism of Fanzor. Cell, 2024
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9CEV
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![BU of 9cev by Molmil](/molmil-images/mine/9cev) | Spizellomyces punctatus Fanzor (SpuFz) State 2 | Descriptor: | DNA (35-MER), DNA (5'-D(P*CP*GP*GP*TP*AP*CP*CP*CP*GP*GP*GP*CP*AP*TP*A)-3'), MAGNESIUM ION, ... | Authors: | Xu, P, Saito, M, Zhang, F. | Deposit date: | 2024-06-27 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.26 Å) | Cite: | Structural insights into the diversity and DNA cleavage mechanism of Fanzor. Cell, 2024
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9CEW
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![BU of 9cew by Molmil](/molmil-images/mine/9cew) | Spizellomyces punctatus Fanzor (SpuFz) State 3 | Descriptor: | DNA (29-MER), DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), DNA (5'-D(P*CP*GP*GP*TP*AP*CP*CP*CP*GP*GP*GP*CP*AP*TP*A)-3'), ... | Authors: | Xu, P, Saito, M, Zhang, F. | Deposit date: | 2024-06-27 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (2.88 Å) | Cite: | Structural insights into the diversity and DNA cleavage mechanism of Fanzor. Cell, 2024
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9CEZ
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![BU of 9cez by Molmil](/molmil-images/mine/9cez) | Spizellomyces punctatus Fanzor (SpuFz) State 6 | Descriptor: | DNA (27-MER), DNA (5'-D(P*TP*AP*CP*CP*CP*GP*GP*GP*CP*AP*TP*A)-3'), MAGNESIUM ION, ... | Authors: | Xu, P, Saito, M, Zhang, F. | Deposit date: | 2024-06-27 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.41 Å) | Cite: | Structural insights into the diversity and DNA cleavage mechanism of Fanzor. Cell, 2024
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9CEY
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![BU of 9cey by Molmil](/molmil-images/mine/9cey) | |
9CEX
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![BU of 9cex by Molmil](/molmil-images/mine/9cex) | Spizellomyces punctatus Fanzor (SpuFz) State 4 | Descriptor: | DNA (29-MER), DNA (5'-D(*(MG)*(MG)P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), DNA (5'-D(P*CP*GP*GP*TP*AP*CP*CP*CP*GP*GP*GP*CP*AP*TP*A)-3'), ... | Authors: | Xu, P, Saito, M, Zhang, F. | Deposit date: | 2024-06-27 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.27 Å) | Cite: | Structural insights into the diversity and DNA cleavage mechanism of Fanzor. Cell, 2024
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9CF2
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![BU of 9cf2 by Molmil](/molmil-images/mine/9cf2) | Parasitella parasitica Fanzor (PpFz) State 3 | Descriptor: | DNA (26-MER), DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), ... | Authors: | Xu, P, Saito, M, Zhang, F. | Deposit date: | 2024-06-27 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.15 Å) | Cite: | Structural insights into the diversity and DNA cleavage mechanism of Fanzor. Cell, 2024
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9CF3
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![BU of 9cf3 by Molmil](/molmil-images/mine/9cf3) | Parasitella parasitica Fanzor (PpFz) State 4 | Descriptor: | DNA (31-MER), DNA (5'-D(P*AP*CP*CP*CP*GP*GP*GP*TP*AP*TP*A)-3'), DNA/RNA (56-MER), ... | Authors: | Xu, P, Saito, M, Zhang, F. | Deposit date: | 2024-06-27 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural insights into the diversity and DNA cleavage mechanism of Fanzor. Cell, 2024
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9FTW
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![BU of 9ftw by Molmil](/molmil-images/mine/9ftw) | |