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4ZT0
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BU of 4zt0 by Molmil
Crystal structure of catalytically-active Streptococcus pyogenes Cas9 in complex with single-guide RNA at 2.9 Angstrom resolution
Descriptor: CRISPR-associated endonuclease Cas9, single-guide RNA
Authors:Jiang, F, Doudna, J.A.
Deposit date:2015-05-14
Release date:2015-07-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A Cas9-guide RNA complex preorganized for target DNA recognition.
Science, 348, 2015
1NU4
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BU of 1nu4 by Molmil
U1A RNA binding domain at 1.8 angstrom resolution reveals a pre-organized C-terminal helix
Descriptor: MAGNESIUM ION, MALONIC ACID, U1A RNA binding domain
Authors:Rupert, P.B, Xiao, H, Ferre-D'Amare, A.R.
Deposit date:2003-01-30
Release date:2003-02-14
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:U1A RNA-binding domain at 1.8 A resolution.
Acta Crystallogr.,Sect.D, 59, 2003
5BJO
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BU of 5bjo by Molmil
Crystal structure of the Corn RNA aptamer in complex with DFHO, site-specific 5-iodo-U
Descriptor: (5Z)-5-[(3,5-difluoro-4-hydroxyphenyl)methylidene]-2-[(E)-(hydroxyimino)methyl]-3-methyl-3,5-dihydro-4H-imidazol-4-one, MAGNESIUM ION, POTASSIUM ION, ...
Authors:Warner, K.D, Song, W, Filonov, G.S, Jaffrey, S.R, Ferre-D'Amare, A.R.
Deposit date:2016-08-21
Release date:2017-09-27
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:A homodimer interface without base pairs in an RNA mimic of red fluorescent protein.
Nat. Chem. Biol., 13, 2017
5BJP
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BU of 5bjp by Molmil
Crystal structure of the Corn RNA aptamer in complex with DFHO, iridium hexammine soak
Descriptor: (5Z)-5-[(3,5-difluoro-4-hydroxyphenyl)methylidene]-2-[(E)-(hydroxyimino)methyl]-3-methyl-3,5-dihydro-4H-imidazol-4-one, DIMETHYL SULFOXIDE, IRIDIUM ION, ...
Authors:Warner, K.D, Song, W, Filonov, G.S, Jaffrey, S.R, Ferre-D'Amare, A.R.
Deposit date:2016-08-21
Release date:2017-09-27
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:A homodimer interface without base pairs in an RNA mimic of red fluorescent protein.
Nat. Chem. Biol., 13, 2017
4RZ9
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BU of 4rz9 by Molmil
Pre-mRNA-splicing factor 38A AS 1-179
Descriptor: Pre-mRNA-splicing factor 38A
Authors:Schuetze, T, Weber, G, Wahl, M.C.
Deposit date:2014-12-19
Release date:2015-12-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:The N-terminal domain of the unusual SR protein hPrp38 is an interaction hub in the spliceosome
To be Published
2I2Y
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BU of 2i2y by Molmil
Solution structure of the RRM of SRp20 bound to the RNA CAUC
Descriptor: (5'-R(*CP*AP*UP*C)-3'), Fusion protein consists of immunoglobulin G-Binding Protein G and Splicing factor, arginine/serine-rich 3
Authors:Hargous, Y.F, Allain, F.H.
Deposit date:2006-08-17
Release date:2006-12-12
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Molecular basis of RNA recognition and TAP binding by the SR proteins SRp20 and 9G8.
Embo J., 25, 2006
4KIT
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BU of 4kit by Molmil
Crystal structure of human Brr2 in complex with the Prp8 Jab1/MPN domain
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Pre-mRNA-processing-splicing factor 8, ...
Authors:Wahl, M.C, Wandersleben, T, Santos, K.F.
Deposit date:2013-05-02
Release date:2013-06-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.598 Å)
Cite:Inhibition of RNA helicase Brr2 by the C-terminal tail of the spliceosomal protein Prp8.
Science, 341, 2013
5UZA
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BU of 5uza by Molmil
Adenine riboswitch aptamer domain labelled with iodo-uridine by position-selective labelling of RNA (PLOR)
Descriptor: ADENINE, MAGNESIUM ION, RNA (71-MER)
Authors:Liu, Y, Stagno, J.R, Wang, Y.-X.
Deposit date:2017-02-25
Release date:2018-02-28
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Incorporation of isotopic, fluorescent, and heavy-atom-modified nucleotides into RNAs by position-selective labeling of RNA.
Nat Protoc, 13, 2018
6D06
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BU of 6d06 by Molmil
Human ADAR2d E488Y mutant complexed with dsRNA containing an abasic site opposite the edited base
Descriptor: Double-stranded RNA-specific editase 1, INOSITOL HEXAKISPHOSPHATE, RNA (5'-R(*CP*AP*GP*AP*GP*CP*CP*CP*CP*CP*NP*AP*GP*CP*AP*UP*CP*GP*CP*GP*AP*GP*C)-3'), ...
Authors:Matthews, M.M, Fisher, A.J, Beal, P.A.
Deposit date:2018-04-10
Release date:2019-02-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:A Bump-Hole Approach for Directed RNA Editing.
Cell Chem Biol, 26, 2019
4RZA
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BU of 4rza by Molmil
Pre-mRNA-splicing factor 38A AS 1-205
Descriptor: Pre-mRNA-splicing factor 38A
Authors:Schuetze, T, Ulrich, A, Wahl, M.C.
Deposit date:2014-12-19
Release date:2015-12-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The N-terminal domain of the unusual SR protein hPrp38 is an interaction hub in the spliceosome
To be Published
3LJ2
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BU of 3lj2 by Molmil
IRE1 complexed with JAK Inhibitor I
Descriptor: 2-TERT-BUTYL-9-FLUORO-3,6-DIHYDRO-7H-BENZ[H]-IMIDAZ[4,5-F]ISOQUINOLINE-7-ONE, Serine/threonine-protein kinase/endoribonuclease IRE1
Authors:Lee, K.P.K, Sicheri, F.
Deposit date:2010-01-25
Release date:2010-05-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.33 Å)
Cite:Flavonol activation defines an unanticipated ligand-binding site in the kinase-RNase domain of IRE1.
Mol.Cell, 38, 2010
4Z7L
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BU of 4z7l by Molmil
Crystal structure of Cas6b
Descriptor: Cas6b, RNA (5'-R(*GP*CP*AP*AP*AP*AP*UP*AP*AP*CP*AP*AP*GP*C)-3'), SULFATE ION
Authors:Li, H.
Deposit date:2015-04-07
Release date:2016-04-13
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.503 Å)
Cite:A Non-Stem-Loop CRISPR RNA Is Processed by Dual Binding Cas6.
Structure, 24, 2016
6WYB
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BU of 6wyb by Molmil
RTX (Reverse Transcription Xenopolymerase) in complex with an RNA/DNA hybrid
Descriptor: 1,2-ETHANEDIOL, 3,3',3''-phosphanetriyltripropanoic acid, DNA polymerase, ...
Authors:Choi, W.S, He, P, Pothukuchy, A, Gollihar, J, Ellington, A.D, Yang, W.
Deposit date:2020-05-12
Release date:2020-08-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:How a B family DNA polymerase has been evolved to copy RNA.
Proc.Natl.Acad.Sci.USA, 117, 2020
5WTK
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BU of 5wtk by Molmil
Crystal structure of RNP complex
Descriptor: CRISPR-associated endoribonuclease C2c2, RNA (58-MER)
Authors:Liu, L, Wang, Y.
Deposit date:2016-12-13
Release date:2017-02-08
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.651 Å)
Cite:Two Distant Catalytic Sites Are Responsible for C2c2 RNase Activities
Cell, 168, 2017
6BFB
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BU of 6bfb by Molmil
Crystal structure of a F. nucleatum FMN riboswitch bound to WG-3
Descriptor: 5-[(3S,4S)-3-(dimethylamino)-4-hydroxypyrrolidin-1-yl]-6-fluoro-4-methyl-8-oxo-3,4-dihydro-8H-1-thia-4,9b-diazacyclopenta[cd]phenalene-9-carboxylic acid, MAGNESIUM ION, RNA (54-MER), ...
Authors:Rizvi, N.F, Fischmann, T.O.
Deposit date:2017-10-26
Release date:2018-02-21
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Discovery of Selective RNA-Binding Small Molecules by Affinity-Selection Mass Spectrometry.
ACS Chem. Biol., 13, 2018
7PTQ
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BU of 7ptq by Molmil
RNA origami 5-helix tile
Descriptor: Chains: C
Authors:McRae, E.K.S, Andersen, E.S.
Deposit date:2021-09-27
Release date:2022-10-05
Last modified:2023-08-02
Method:ELECTRON MICROSCOPY (4.08 Å)
Cite:Structure, folding and flexibility of co-transcriptional RNA origami.
Nat Nanotechnol, 18, 2023
7PTS
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BU of 7pts by Molmil
RNA origami 5-helix tile
Descriptor: 5HT-B
Authors:McRae, E.K.S, Andersen, E.S.
Deposit date:2021-09-27
Release date:2022-10-05
Last modified:2023-08-02
Method:ELECTRON MICROSCOPY (5.71 Å)
Cite:Structure, folding and flexibility of co-transcriptional RNA origami.
Nat Nanotechnol, 18, 2023
5BTP
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BU of 5btp by Molmil
Fusobacterium ulcerans ZTP riboswitch bound to ZMP
Descriptor: AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE, MAGNESIUM ION, POTASSIUM ION, ...
Authors:Jones, C.P, Ferre-D'Amare, A.R.
Deposit date:2015-06-03
Release date:2015-08-12
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.816 Å)
Cite:Recognition of the bacterial alarmone ZMP through long-distance association of two RNA subdomains.
Nat.Struct.Mol.Biol., 22, 2015
6W1X
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BU of 6w1x by Molmil
Cryo-EM structure of anti-CRISPR AcrIF9, bound to the type I-F crRNA-guided CRISPR surveillance complex
Descriptor: CRISPR-associated endonuclease Cas6/Csy4, CRISPR-associated protein Csy1, CRISPR-associated protein Csy3, ...
Authors:Hirschi, M, Santiago-Frangos, A, Wilkinson, R, Golden, S.M, Wiedenheft, B, Lander, G.
Deposit date:2020-03-04
Release date:2020-05-13
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:AcrIF9 tethers non-sequence specific dsDNA to the CRISPR RNA-guided surveillance complex.
Nat Commun, 11, 2020
7D8U
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BU of 7d8u by Molmil
Crystal structure of the C-terminal domain of pNP868R from African swine fever virus
Descriptor: 1,2-ETHANEDIOL, FORMIC ACID, GTP--RNA guanylyltransferase, ...
Authors:Du, X, Geng, Z, Zhang, H.
Deposit date:2020-10-10
Release date:2020-12-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure and Biochemical Characteristic of the Methyltransferase (MTase) Domain of RNA Capping Enzyme from African Swine Fever Virus.
J.Virol., 2020
1R3F
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BU of 1r3f by Molmil
Crystal Structure of tRNA Pseudouridine Synthase TruB and Its RNA Complex: RNA-protein Recognition Through a Combination of Rigid Docking and Induced Fit
Descriptor: tRNA pseudouridine synthase B
Authors:Pan, H, Agarwalla, S, Moustakas, D.T, Finer-Moore, J, Stroud, R.M.
Deposit date:2003-10-01
Release date:2003-11-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure of tRNA Pseudouridine Synthase TruB and Its RNA Complex: RNA Recognition Through a Combination of Rigid Docking and Induced Fit
Proc.Natl.Acad.Sci.USA, 100, 2003
5TSN
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BU of 5tsn by Molmil
Crystal structures of Norwalk virus polymerase bound to an RNA primer-template duplex
Descriptor: MANGANESE (II) ION, Norwalk virus polymerase, RNA (5'-R(*UP*GP*CP*CP*CP*GP*GP*G)-3')
Authors:Shaik, M.M, Ng, K.K.
Deposit date:2016-10-30
Release date:2017-04-12
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Norovirus RNA-dependent RNA polymerase: A computational study of metal-binding preferences.
Proteins, 85, 2017
1D9H
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BU of 1d9h by Molmil
Structural origins of the exonuclease resistance of a zwitterionic RNA
Descriptor: DNA/RNA (5'-D(*GP*CP*GP*TP*AP)-R(*(U31)P)-D(*AP*CP*GP*C)-3')
Authors:Teplova, M, Wallace, S.T, Tereshko, V, Minasov, G, Simons, A.M, Cook, P.D, Manoharan, M, Egli, M.
Deposit date:1999-10-27
Release date:1999-12-02
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural origins of the exonuclease resistance of a zwitterionic RNA
Proc.Natl.Acad.Sci.USA, 96, 1999
6DOM
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BU of 6dom by Molmil
Crystal Structure of Bacillus Halodurans Ribonuclease H1 in Complex with an RNA/DNA Hybrid: Reaction in 2 mM Mg2+ and 50 mM K+ for 120 s at 21 C
Descriptor: 1,2-ETHANEDIOL, 5'-R(*AP*CP*AP*U)-3' portion of cleaved RNA 5'-R(*AP*CP*AP*UP*CP*G)-3', 5'-R(P*CP*G)-3' portion of cleaved RNA (5'-R(*AP*CP*AP*UP*CP*G)-3'), ...
Authors:Samara, N.L, Yang, W.
Deposit date:2018-06-09
Release date:2018-08-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.425 Å)
Cite:Cation trafficking propels RNA hydrolysis.
Nat. Struct. Mol. Biol., 25, 2018
6DP2
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BU of 6dp2 by Molmil
Crystal Structure of Bacillus Halodurans Ribonuclease H1 in Complex with an RNA/DNA Hybrid: Reaction in 7.5 mM Mg2+ and 75 mM K+ for 40 s at 21 C
Descriptor: 1,2-ETHANEDIOL, 5'-R(*AP*CP*AP*U)-3' portion of uncleaved RNA 5'-R(*AP*CP*AP*UP*CP*G)-3', 5'-R(P*CP*G)-3' portion of uncleaved RNA 5'-R(*AP*CP*AP*UP*CP*G)-3', ...
Authors:Samara, N.L, Yang, W.
Deposit date:2018-06-09
Release date:2018-08-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.662 Å)
Cite:Cation trafficking propels RNA hydrolysis.
Nat. Struct. Mol. Biol., 25, 2018

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数据于2024-07-10公开中

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