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4Q4J
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BU of 4q4j by Molmil
Structure of crosslinked TM287/288_S498C_S520C mutant
Descriptor: ABC transporter, Uncharacterized ABC transporter ATP-binding protein TM_0288
Authors:Hohl, M, Schoeppe, J, Gruetter, M.G, Seeger, M.A.
Deposit date:2014-04-14
Release date:2014-07-16
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for allosteric cross-talk between the asymmetric nucleotide binding sites of a heterodimeric ABC exporter.
Proc.Natl.Acad.Sci.USA, 111, 2014
4Q4H
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BU of 4q4h by Molmil
TM287/288 in its apo state
Descriptor: ABC transporter, Uncharacterized ABC transporter ATP-binding protein TM_0288
Authors:Hohl, M, Gruetter, M.G, Seeger, M.A.
Deposit date:2014-04-14
Release date:2014-07-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.527 Å)
Cite:Structural basis for allosteric cross-talk between the asymmetric nucleotide binding sites of a heterodimeric ABC exporter.
Proc.Natl.Acad.Sci.USA, 111, 2014
7AHD
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BU of 7ahd by Molmil
OpuA (E190Q) occluded
Descriptor: ABC transporter permease subunit, ABC-type proline/glycine betaine transport system ATPase component, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Sikkema, H.R, Rheinberger, J, Paulino, C, Poolman, B.
Deposit date:2020-09-24
Release date:2020-11-25
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Gating by ionic strength and safety check by cyclic-di-AMP in the ABC transporter OpuA.
Sci Adv, 6, 2020
7AHH
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BU of 7ahh by Molmil
OpuA inhibited inward-facing, SBD docked
Descriptor: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, ABC transporter permease subunit, ABC-type proline/glycine betaine transport system ATPase component, ...
Authors:Sikkema, H.R, Rheinberger, J, Paulino, C, Poolman, B.
Deposit date:2020-09-24
Release date:2020-11-25
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Gating by ionic strength and safety check by cyclic-di-AMP in the ABC transporter OpuA.
Sci Adv, 6, 2020
7AHE
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BU of 7ahe by Molmil
OpuA inhibited inward facing
Descriptor: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, ABC transporter permease subunit, ABC-type proline/glycine betaine transport system ATPase component
Authors:Sikkema, H.R, Rheinberger, J, Paulino, C, Poolman, B.
Deposit date:2020-09-24
Release date:2020-11-25
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Gating by ionic strength and safety check by cyclic-di-AMP in the ABC transporter OpuA.
Sci Adv, 6, 2020
7AHC
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BU of 7ahc by Molmil
OpuA apo inward-facing
Descriptor: ABC transporter permease subunit, ABC-type proline/glycine betaine transport system ATPase component
Authors:Sikkema, H.R, Rheinberger, J, Paulino, C, Poolman, B.
Deposit date:2020-09-24
Release date:2020-11-25
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Gating by ionic strength and safety check by cyclic-di-AMP in the ABC transporter OpuA.
Sci Adv, 6, 2020
7B7D
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BU of 7b7d by Molmil
Yeast 80S ribosome bound to eEF3 and A/A- and P/P-tRNAs
Descriptor: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
Authors:Ranjan, N, Pochopien, A.A, Wu, C.C, Beckert, B, Blanchet, S, Green, R, Rodnina, M.V, Wilson, D.N.
Deposit date:2020-12-10
Release date:2021-03-10
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:eEF3 promotes late stages of tRNA translocation including E-tRNA release from the ribosome
To Be Published
7ARM
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BU of 7arm by Molmil
LolCDE in complex with lipoprotein and LolA
Descriptor: (2S)-3-hydroxypropane-1,2-diyl dihexadecanoate, LPP, Lipoprotein-releasing ABC transporter permease subunit LolC, ...
Authors:Tang, X.D, Chang, S.H, Zhang, K, Wang, T, Luo, Q.H, Qiao, W, Wang, C, Shen, C.R, Zhang, Z.B, Zhang, Z.Y, Zhu, X.F, Wei, X.W, Dong, C.J, Zhang, X, Dong, H.H.
Deposit date:2020-10-25
Release date:2021-04-07
Last modified:2021-04-28
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural basis for bacterial lipoprotein relocation by the transporter LolCDE.
Nat.Struct.Mol.Biol., 28, 2021
7ARL
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BU of 7arl by Molmil
LolCDE in complex with lipoprotein and ADP
Descriptor: (2S)-3-hydroxypropane-1,2-diyl dihexadecanoate, ADENOSINE-5'-DIPHOSPHATE, LPP, ...
Authors:Tang, X.D, Chang, S.H, Zhang, K, Wang, T, Luo, Q.H, Qiao, W, Wang, C, Shen, C.R, Zhang, Z.B, Zhang, Z.Y, Zhu, X.F, Wei, X.W, Dong, C.J, Zhang, X, Dong, H.H.
Deposit date:2020-10-25
Release date:2021-04-07
Last modified:2021-04-28
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural basis for bacterial lipoprotein relocation by the transporter LolCDE.
Nat.Struct.Mol.Biol., 28, 2021
7ARJ
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BU of 7arj by Molmil
LolCDE in complex with lipoprotein and AMPPNP complex undimerized form
Descriptor: (2S)-3-hydroxypropane-1,2-diyl dihexadecanoate, LPP, Lipoprotein-releasing ABC transporter permease subunit LolC, ...
Authors:Tang, X.D, Chang, S.H, Zhang, K, Wang, T, Luo, Q.H, Qiao, W, Wang, C, Zhang, Z.B, Zhang, Z.Y, Zhu, X.F, Dong, C.J, Zhang, X, Dong, H.H.
Deposit date:2020-10-25
Release date:2021-04-07
Last modified:2021-04-28
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural basis for bacterial lipoprotein relocation by the transporter LolCDE.
Nat.Struct.Mol.Biol., 28, 2021
7ARK
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BU of 7ark by Molmil
LolCDE in complex with AMP-PNP in the closed NBD state
Descriptor: Lipoprotein-releasing ABC transporter permease subunit LolC, Lipoprotein-releasing system ATP-binding protein LolD, Lipoprotein-releasing system transmembrane protein LolE, ...
Authors:Tang, X.D, Chang, S.H, Zhang, K, Wang, T, Luo, Q.H, Qiao, W, Wang, C, Zhang, Z.B, Zhang, Z.Y, Zhu, X.F, Dong, C.J, Zhang, X, Dong, H.H.
Deposit date:2020-10-25
Release date:2021-04-07
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural basis for bacterial lipoprotein relocation by the transporter LolCDE.
Nat.Struct.Mol.Biol., 28, 2021
7ARI
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BU of 7ari by Molmil
LolCDE apo structure
Descriptor: Lipoprotein-releasing ABC transporter permease subunit LolC, Lipoprotein-releasing system ATP-binding protein LolD, Lipoprotein-releasing system transmembrane protein LolE
Authors:Tang, X.D, Chang, S.H, Zhang, K, Wang, T, Luo, Q.H, Qiao, W, Wang, C, Zhang, Z.B, Zhang, Z.Y, Zhu, X.F, Dong, C.J, Zhang, X, Dong, H.H.
Deposit date:2020-10-25
Release date:2021-04-07
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis for bacterial lipoprotein relocation by the transporter LolCDE.
Nat.Struct.Mol.Biol., 28, 2021
7ARH
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BU of 7arh by Molmil
LolCDE in complex with lipoprotein
Descriptor: (2S)-3-hydroxypropane-1,2-diyl dihexadecanoate, LPP, Lipoprotein-releasing ABC transporter permease subunit LolC, ...
Authors:Tang, X.D, Chang, S.H, Zhang, K, Wang, T, Luo, Q.H, Qiao, W, Wang, C, Zhang, Z.B, Zhang, Z.Y, Zhu, X.F, Dong, C.J, Zhang, X, Dong, H.H.
Deposit date:2020-10-25
Release date:2021-04-07
Last modified:2021-04-28
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis for bacterial lipoprotein relocation by the transporter LolCDE.
Nat.Struct.Mol.Biol., 28, 2021
4R9U
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BU of 4r9u by Molmil
Structure of vitamin B12 transporter BtuCD in a nucleotide-bound outward facing state
Descriptor: LAURYL DIMETHYLAMINE-N-OXIDE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Korkhov, V.M, Mireku, S.A, Veprintsev, D.B, Locher, K.P.
Deposit date:2014-09-08
Release date:2014-11-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.785 Å)
Cite:Structure of AMP-PNP-bound BtuCD and mechanism of ATP-powered vitamin B12 transport by BtuCD-F.
Nat.Struct.Mol.Biol., 21, 2014
7A65
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BU of 7a65 by Molmil
Nanodisc reconstituted, drug-free human ABCB1 in complex with MRK16 Fab
Descriptor: CHOLESTEROL, MRK16 Fab-fragment heavy chain, MRK16 Fab-fragment light chain, ...
Authors:Nosol, K, Locher, K.P.
Deposit date:2020-08-25
Release date:2020-10-14
Last modified:2020-10-28
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1.
Proc.Natl.Acad.Sci.USA, 117, 2020
7A6E
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BU of 7a6e by Molmil
Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and tariquidar
Descriptor: CHOLESTEROL, MRK16 Fab-fragment heavy chain, MRK16 Fab-fragment light chain, ...
Authors:Nosol, K, Locher, K.P.
Deposit date:2020-08-25
Release date:2020-10-14
Last modified:2020-10-28
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1.
Proc.Natl.Acad.Sci.USA, 117, 2020
4RFS
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BU of 4rfs by Molmil
Structure of a pantothenate energy coupling factor transporter
Descriptor: Energy-coupling factor transporter ATP-binding protein EcfA1, Energy-coupling factor transporter ATP-binding protein EcfA2, Energy-coupling factor transporter transmembrane protein EcfT, ...
Authors:Zhang, M, Bao, Z, Zhao, Q, Guo, H, Xu, K, Zhang, P.
Deposit date:2014-09-27
Release date:2014-12-24
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.232 Å)
Cite:Structure of a pantothenate transporter and implications for ECF module sharing and energy coupling of group II ECF transporters.
Proc.Natl.Acad.Sci.USA, 111, 2014
6ZME
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BU of 6zme by Molmil
SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-eERF1 ribosome complex
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
Deposit date:2020-07-02
Release date:2020-08-12
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2.
Science, 369, 2020
6ZU9
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BU of 6zu9 by Molmil
Structure of a yeast ABCE1-bound 48S initiation complex
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
Deposit date:2020-07-22
Release date:2020-10-28
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes.
Embo J., 40, 2021
7A69
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BU of 7a69 by Molmil
Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and vincristine
Descriptor: CHOLESTEROL, MRK16 Fab-fragment heavy chain, MRK16 Fab-fragment light chain, ...
Authors:Nosol, K, Locher, K.P.
Deposit date:2020-08-25
Release date:2020-10-21
Last modified:2020-10-28
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1.
Proc.Natl.Acad.Sci.USA, 117, 2020
7A6F
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BU of 7a6f by Molmil
Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and zosuquidar
Descriptor: CHOLESTEROL, MRK16 Fab-fragment heavy chain, MRK16 Fab-fragment light chain, ...
Authors:Nosol, K, Locher, K.P.
Deposit date:2020-08-25
Release date:2020-10-14
Last modified:2020-10-28
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1.
Proc.Natl.Acad.Sci.USA, 117, 2020
4P31
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BU of 4p31 by Molmil
Crystal structure of a selenomethionine derivative of E. coli LptB in complex with ADP-Magensium
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Lipopolysaccharide export system ATP-binding protein LptB, MAGNESIUM ION
Authors:Sherman, D.J, Lazarus, M.B, Murphy, L, Liu, C, Walker, S, Ruiz, N, Kahne, D.
Deposit date:2014-03-05
Release date:2014-03-26
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Decoupling catalytic activity from biological function of the ATPase that powers lipopolysaccharide transport.
Proc.Natl.Acad.Sci.USA, 111, 2014
6ZVJ
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BU of 6zvj by Molmil
Structure of a human ABCE1-bound 43S pre-initiation complex - State II
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
Authors:Kratzat, H, Mackens-Kiani, T, Ameismeier, A, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
Deposit date:2020-07-24
Release date:2020-10-07
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes.
Embo J., 40, 2021
7A6C
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BU of 7a6c by Molmil
Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and elacridar
Descriptor: CHOLESTEROL, If kappa light chain, MRK16 Fab-fragment heavy chain, ...
Authors:Nosol, K, Locher, K.P.
Deposit date:2020-08-25
Release date:2020-10-14
Last modified:2020-10-28
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1.
Proc.Natl.Acad.Sci.USA, 117, 2020
4Q9L
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BU of 4q9l by Molmil
P-glycoprotein cocrystallised with QZ-Phe
Descriptor: (30F)F(30F)F(30F)F Peptide, Multidrug resistance protein 1A
Authors:McGrath, A.P, Szewczyk, P, Chang, G.
Deposit date:2014-05-01
Release date:2015-03-04
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Snapshots of ligand entry, malleable binding and induced helical movement in P-glycoprotein.
Acta Crystallogr.,Sect.D, 71, 2015

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数据于2024-07-10公开中

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