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2HGM	NMR structure of the second qRRM domain of human hnRNP F Descriptor: Heterogeneous nuclear ribonucleoprotein F Authors: Dominguez, C, Allain, F.H.-T. Deposit date: 2006-06-27 Release date: 2006-07-11 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: NMR structure of the three quasi RNA recognition motifs (qRRMs) of human hnRNP F and interaction studies with Bcl-x G-tract RNA: a novel mode of RNA recognition. Nucleic Acids Res., 34, 2006
2KM8	Interdomain RRM packing contributes to RNA recognition in the rna15, hrp1, anchor RNA 3' processing ternary complex Descriptor: 5'-R(P*UP*AP*UP*AP*UP*AP*UP*AP*AP*UP*AP*AP*U)-3', Nuclear polyadenylated RNA-binding protein 4, mRNA 3'-end-processing protein RNA15 Authors: Leeper, T.C, Varani, G. Deposit date: 2009-07-24 Release date: 2010-07-28 Last modified: 2024-05-08 Method: SOLUTION NMR Cite: Novel Protein-Protein Contacts Facilitate mRNA 3'-Processing Signal Recognition by Rna15 and Hrp1. J.Mol.Biol., 401, 2010
2KRB	Solution structure of EIF3B-RRM bound to EIF3J peptide Descriptor: Eukaryotic translation initiation factor 3 subunit B, Eukaryotic translation initiation factor 3 subunit J Authors: Elantak, L, Wagner, S, Herrmannova, A, Janoskova, M, Rutkai, E, Lukavsky, P.J, Valasek, L. Deposit date: 2009-12-16 Release date: 2010-01-05 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: The indispensable N-terminal half of eIF3j/HCR1 co-operates with its structurally conserved binding partner eIF3b/PRT1-RRM and eIF1A in stringent AUG selection To be Published
2KYX	Solution structure of the RRM domain of CYP33 Descriptor: Peptidyl-prolyl cis-trans isomerase E Authors: Park, S, Bushweller, J.H. Deposit date: 2010-06-09 Release date: 2010-08-25 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: The PHD3 domain of MLL acts as a CYP33-regulated switch between MLL-mediated activation and repression . Biochemistry, 49, 2010
2KVI	Structure of Nab3 RRM Descriptor: Nuclear polyadenylated RNA-binding protein 3 Authors: Pergoli, R, Kubicek, K, Hobor, F, Pasulka, J, Stefl, R. Deposit date: 2010-03-15 Release date: 2010-11-17 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Solution structure and RNA-binding study of RNA-recognition motif of Nab3 J.Biol.Chem., 2010
2KXH	Solution structure of the first two RRM domains of FIR in the complex with FBP Nbox peptide Descriptor: Poly(U)-binding-splicing factor PUF60, peptide of Far upstream element-binding protein 1 Authors: Cukier, C.D, Ramos, A, Hollingworth, D, Diaz-Moreno, I, Kelly, G. Deposit date: 2010-05-05 Release date: 2010-08-18 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Molecular basis of FIR-mediated c-myc transcriptional control. Nat.Struct.Mol.Biol., 17, 2010
2KXF	Solution structure of the first two RRM domains of FBP-interacting repressor (FIR) Descriptor: Poly(U)-binding-splicing factor PUF60 Authors: Cukier, C.D, Ramos, A, Hollingworth, D, Diaz-Moreno, I, Kelly, G. Deposit date: 2010-05-04 Release date: 2010-08-18 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Molecular basis of FIR-mediated c-myc transcriptional control. Nat.Struct.Mol.Biol., 17, 2010
2I38	Solution structure of the RRM of SRp20 Descriptor: Fusion protein consists of immunoglobulin G-Binding Protein G and Splicing factor, arginine/serine-rich 3 Authors: Hargous, Y.F, Allain, F.H.T. Deposit date: 2006-08-17 Release date: 2006-12-12 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Molecular basis of RNA recognition and TAP binding by the SR proteins SRp20 and 9G8. Embo J., 25, 2006
2KXN	NMR structure of human Tra2beta1 RRM in complex with AAGAAC RNA Descriptor: 5'-R(*AP*AP*GP*AP*AP*C)-3', Transformer-2 protein homolog beta Authors: Clery, A, Jayne, S, Benderska, N, Dominguez, C, Stamm, S, Allain, F.H.-T. Deposit date: 2010-05-10 Release date: 2011-03-16 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Molecular basis of purine-rich RNA recognition by the human SR-like protein Tra2-beta1 Nat.Struct.Mol.Biol., 18, 2011
2LA6	Solution NMR Structure of RRM domain of RNA-binding protein FUS from homo sapiens, Northeast Structural Genomics Consortium Target HR6430A Descriptor: RNA-binding protein FUS Authors: Liu, G, Xiao, R, Janjua, H, Ciccosanti, C, Wang, H, Lee, H, Acton, T.B, Everett, J.K, Huang, Y.J, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) Deposit date: 2011-03-04 Release date: 2011-05-04 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Northeast Structural Genomics Consortium Target HR6430A To be Published
2LEC	Solution structure of human SRSF2 (SC35) RRM in complex with 5'-UGGAGU-3' Descriptor: RNA (5'-R(*UP*GP*GP*AP*GP*U)-3'), Serine/arginine-rich splicing factor 2 Authors: Daubner, G.M, Clery, A, Jayne, S, Stevenin, J, Allain, F.H.-T. Deposit date: 2011-06-15 Release date: 2011-11-23 Last modified: 2024-05-08 Method: SOLUTION NMR Cite: A syn-anti conformational difference allows SRSF2 to recognize guanines and cytosines equally well. Embo J., 31, 2012
2LA4	NMR structure of the C-terminal RRM domain of poly(U) binding 1 Descriptor: Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1 Authors: Santiveri, C.M, Mirassou, Y, Rico-Lastres, P, Martinez-Lumbreras, S, Perez-Canadillas, J.M. Deposit date: 2011-03-01 Release date: 2011-09-28 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Pub1p C-terminal RRM domain interacts with Tif4631p through a conserved region neighbouring the Pab1p binding site Plos One, 6, 2011
2LCW	solution structure of FUS/TLS RRM domain Descriptor: RNA-binding protein FUS Authors: Liu, X, Ren, J, Niu, C, Gong, W, Feng, W. Deposit date: 2011-05-10 Release date: 2012-06-06 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: TLS-RRM is a promiscuous nucleic acid binding domain To be Published
9F7H	UP1 in complex with Z45617795 Descriptor: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed, N-(2-phenylethyl)methanesulfonamide Authors: Dunnett, L, Prischi, F. Deposit date: 2024-05-03 Release date: 2024-05-15 Method: X-RAY DIFFRACTION (1.43 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F4O	UP1 in complex with Z991506900 Descriptor: (3~{R})-3-methyl-1-(6-methylpyridin-2-yl)piperazine, Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-28 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F55	UP1 in complex with Z235361315 Descriptor: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed, ~{N}-(3-azanyl-2-methyl-phenyl)propanamide Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-28 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F1S	Structure of UP1 S4ES6E phosphomimetic mutant Descriptor: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-20 Release date: 2024-05-01 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Structure of UP1 S4ES6E phosphomimetic mutant To Be Published
9F4K	UP1 in complex with ZINC72259689 Descriptor: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed, ~{N}-(cyclobutylmethyl)-1,3-dimethyl-pyrazole-4-carboxamide Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-28 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F4Q	UP1 in complex with Z641239276 Descriptor: 5-(2-phenylethylamino)pyrimidine-2,4-diol, Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-28 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F51	UP1 in complex with Z608065044 Descriptor: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed, ~{N},~{N}-dimethyl-1~{H}-pyrazole-4-sulfonamide Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-28 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F4F	UP1 in complex with Z86417414 Descriptor: 2-fluoranyl-~{N}-(1,3,4-thiadiazol-2-yl)benzamide, Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-27 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F5D	UP1 in complex with Z641230552 Descriptor: 5-[(phenylmethyl)amino]-1~{H}-pyrimidine-2,4-dione, Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-28 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F7F	UP1 in complex with Z1491353358 Descriptor: (3S)-1-(phenylsulfonyl)pyrrolidin-3-amine, Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed Authors: Dunnett, L, Prischi, F. Deposit date: 2024-05-03 Release date: 2024-05-15 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F4N	UP1 in complex with Z137811222 Descriptor: 1-[4-(3-phenylpropyl)piperazin-1-yl]ethan-1-one, Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-28 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F4T	UP1 in complex with EN300-805013 Descriptor: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed, N-(4-methoxyphenyl)glycinamide Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-28 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.42 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published

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