6SA8
 
 | | ring-like DARPin-Armadillo fusion H83_D01 | | Descriptor: | 1,2-ETHANEDIOL, LYS-ARG-LYS-ARG-LYS-ARG-LYS-ARG-LYS-ARG, ring-like DARPin-Armadillo fusion H83_D01 | | Authors: | Ernst, P, Honegger, A, van der Valk, F, Ewald, C, Mittl, P.R.E, Plucktun, A. | | Deposit date: | 2019-07-16 | | Release date: | 2019-11-20 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Rigid fusions of designed helical repeat binding proteins efficiently protect a binding surface from crystal contacts.
Sci Rep, 9, 2019
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6S9M
 | | Designed Armadillo Repeat protein Lock2 fused to target peptide KRKRKAKITW | | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, Lock2_KRKRKAKITW, ... | | Authors: | Ernst, P, Zosel, F, Reichen, C, Schuler, B, Pluckthun, A. | | Deposit date: | 2019-07-15 | | Release date: | 2020-02-19 | | Last modified: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure-Guided Design of a Peptide Lock for Modular Peptide Binders.
Acs Chem.Biol., 15, 2020
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6SA6
 | | DARPin-Armadillo fusion A5 | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, DARPin-Armadillo fusion A5 | | Authors: | Ernst, P, Honegger, A, van der Valk, F, Ewald, C, Mittl, P.R.E, Pluckthun, A. | | Deposit date: | 2019-07-16 | | Release date: | 2019-11-20 | | Last modified: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Rigid fusions of designed helical repeat binding proteins efficiently protect a binding surface from crystal contacts.
Sci Rep, 9, 2019
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2LXO
 | | Identification of the Structural Traits Mediating the Antimicrobial Activity of a Chimeric Peptide of HBD2 and HBD3 | | Descriptor: | Chimeric Peptide | | Authors: | Spudy, B, Soennichsen, F.D, Waetzig, G.H, Grotzinger, J, Jung, S. | | Deposit date: | 2012-08-30 | | Release date: | 2013-08-14 | | Last modified: | 2023-12-13 | | Method: | SOLUTION NMR | | Cite: | Identification of structural traits that increase the antimicrobial activity of a chimeric peptide of human beta-defensins 2 and 3.
Biochem.Biophys.Res.Commun., 427, 2012
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6SRW
 | | Kemp Eliminase HG3.17 mutant Q50F, E47N, N300D Complexed with Transition State Analog 6-Nitrobenzotriazole | | Descriptor: | 6-NITROBENZOTRIAZOLE, GLYCEROL, Kemp Eliminase HG3.17 Q50F | | Authors: | Bloch, J.S, Pinkas, D.M, Hilvert, D. | | Deposit date: | 2019-09-06 | | Release date: | 2020-04-01 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Contribution of Oxyanion Stabilization to Kemp Eliminase Efficiencyproficiency
Acs Catalysis, 2020
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2JWS
 | | Solution NMR structures of two designed proteins with 88% sequence identity but different fold and function | | Descriptor: | Ga88 | | Authors: | He, Y, Chen, Y, Alexander, P, Bryan, P, Orban, J. | | Deposit date: | 2007-10-24 | | Release date: | 2008-09-09 | | Last modified: | 2024-05-08 | | Method: | SOLUTION NMR | | Cite: | NMR structures of two designed proteins with high sequence identity but different fold and function
Proc.Natl.Acad.Sci.Usa, 105, 2008
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6R28
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2N63
 | | Structure of C4VG16KRKP | | Descriptor: | PENTANOIC ACID, antimicrobial peptide C4VG16KRKP | | Authors: | Bhunia, A, Datta, A. | | Deposit date: | 2015-08-11 | | Release date: | 2016-03-23 | | Last modified: | 2024-01-24 | | Method: | SOLUTION NMR | | Cite: | Designing potent antimicrobial peptides by disulphide linked dimerization and N-terminal lipidation to increase antimicrobial activity and membrane perturbation: Structural insights into lipopolysaccharide binding.
J Colloid Interface Sci, 461, 2016
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6REL
 | | Crystal structure of Pizza6-SH with CdCl2 nanocrystal | | Descriptor: | CADMIUM ION, CHLORIDE ION, Pizza6-SH | | Authors: | Noguchi, H, Clarke, D.E, Gryspeerdt, J.L, Feyter, S.D, Voet, A.R.D. | | Deposit date: | 2019-04-12 | | Release date: | 2020-05-13 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.08 Å) | | Cite: | Artificial beta-Propeller Protein-based Hydrolases
To Be Published
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6REI
 | | Crystal structure of Pizza6-S with Cd2+ | | Descriptor: | CADMIUM ION, CHLORIDE ION, GLYCEROL, ... | | Authors: | Noguchi, H, Clarke, D.E, Gryspeerdt, J.L, Feyter, S.D, Voet, A.R.D. | | Deposit date: | 2019-04-12 | | Release date: | 2020-05-13 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Artificial beta-Propeller Protein-based Hydrolases
To Be Published
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6REM
 | | Crystal structure of Pizza6-SH with Sulphate ion | | Descriptor: | Pizza6-SH, SULFATE ION | | Authors: | Noguchi, H, Clarke, D.E, Gryspeerdt, J.L, Feyter, S.D, Voet, A.R.D. | | Deposit date: | 2019-04-12 | | Release date: | 2020-05-13 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Artificial beta-Propeller Protein-based Hydrolases
To Be Published
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2N8C
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2JRE
 | | C60-1, a PDZ domain designed using statistical coupling analysis | | Descriptor: | C60-1 PDZ domain peptide | | Authors: | Larson, C, Stiffler, M, Li, P, Rosen, M, MacBeath, G, Ranganathan, R. | | Deposit date: | 2007-06-25 | | Release date: | 2008-07-01 | | Last modified: | 2023-12-20 | | Method: | SOLUTION NMR | | Cite: | C60-1, a PDZ domain designed using statistical coupling analysis
To be Published
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2KLW
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2JWU
 | | Solution NMR structures of two designed proteins with 88% sequence identity but different fold and function | | Descriptor: | Gb88 | | Authors: | He, Y, Chen, Y, Alexander, P, Bryan, P, Orban, J. | | Deposit date: | 2007-10-25 | | Release date: | 2008-09-09 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | NMR structures of two designed proteins with high sequence identity but different fold and function
Proc.Natl.Acad.Sci.Usa, 105, 2008
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2L96
 | | Solution structure of LAK160-P7 | | Descriptor: | LAK160-P7 | | Authors: | Vermeer, L.S, Bui, T.T, Lan, Y, Jumagulova, E, Kozlowska, J, McIntyre, C, Drake, A.F, Mason, J.A. | | Deposit date: | 2011-02-01 | | Release date: | 2012-02-01 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | The role of proline induced conformational flexibility in determining the antibacterial potency of linear cationic alpha-helical peptides
To be Published
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2LR2
 | | Designed IgG and lanthanide binding probe for solution NMR, MRI and luminescence microscopy | | Descriptor: | Immunoglobulin G-binding protein A | | Authors: | Barb, A.W, Ho, T.G, Prestegard, J.H. | | Deposit date: | 2012-03-21 | | Release date: | 2012-09-12 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Lanthanide binding and IgG affinity construct: Potential applications in solution NMR, MRI, and luminescence microscopy.
Protein Sci., 21, 2012
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6SRZ
 | | Kemp Eliminase HG3.17 mutant Q50H, E47N, N300D Complexed with Transition State Analog 6-Nitrobenzotriazole | | Descriptor: | 6-NITROBENZOTRIAZOLE, GLYCEROL, Kemp Eliminase HG3.17 Q50H, ... | | Authors: | Bloch, J.S, Pinkas, D.M, Hilvert, D. | | Deposit date: | 2019-09-06 | | Release date: | 2020-04-01 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Contribution of Oxyanion Stabilization to Kemp Eliminase Efficiencyproficiency
Acs Catalysis, 2020
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2LQ4
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2LFD
 | | Solution NMR structure of Diiron protein in presence of 2 eq Zn2+, Northeast Structural Genomics Consortium Target OR21 | | Descriptor: | Diiron protein, ZINC ION | | Authors: | Wu, Y, Pires, M, Mills, J.L, Reig, A, Szyperski, T, Degrado, W, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2011-06-29 | | Release date: | 2011-08-24 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Solution NMR structure of Diiron protein in presence of 2 eq Zn2+
To be Published
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2MTT
 | | Non-reducible analogues of alpha-conotoxin RgIA: [3,12]-cis dicarba RgIA | | Descriptor: | Dicarba Analogues of alpha-Conotoxin RgIA | | Authors: | Chhabra, S, Robinson, S.D, Norton, R.S. | | Deposit date: | 2014-08-31 | | Release date: | 2014-11-26 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Dicarba Analogues of alpha-Conotoxin RgIA. Structure, Stability, and Activity at Potential Pain Targets.
J.Med.Chem., 57, 2014
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2N09
 | | NMR structure of a short hydrophobic 11mer peptide in DMSO-d6/H2O (1:3) solution | | Descriptor: | Short hydrophobic peptide with cyclic constraints | | Authors: | Hoang, H.N, Song, K, Hill, T.A, Derksen, D.R, Edmonds, D.J, Kok, W.M, Limberakis, C, Liras, S, Loria, P.M, Mascitti, V, Mathiowetz, A.M, Mitchell, J.M, Piotrowski, D.W, Price, D.A, Stanton, R.V, Suen, J.Y, Withka, J.M, Griffith, D.A, Fairlie, D.P. | | Deposit date: | 2015-03-04 | | Release date: | 2015-04-15 | | Last modified: | 2015-05-27 | | Method: | SOLUTION NMR | | Cite: | Short Hydrophobic Peptides with Cyclic Constraints Are Potent Glucagon-like Peptide-1 Receptor (GLP-1R) Agonists.
J.Med.Chem., 58, 2015
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2K76
 | | Solution structure of a paralog-specific Mena binder by NMR | | Descriptor: | pGolemi | | Authors: | Link, N.M, Hunke, C, Eichler, J, Bayer, P. | | Deposit date: | 2008-08-03 | | Release date: | 2009-06-16 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | The solution structure of pGolemi, a high affinity Mena EVH1 binding miniature protein, suggests explanations for paralog-specific binding to Ena/VASP homology (EVH) 1 domains.
Biol.Chem., 390, 2009
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2N65
 | | Disulphide linked homodimer of designed antimicrobial peptide VG16KRKP | | Descriptor: | antimicrobial peptide VG16KRKP | | Authors: | Datta, A, Bhunia, A. | | Deposit date: | 2015-08-12 | | Release date: | 2016-03-23 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Designing potent antimicrobial peptides by disulphide linked dimerization and N-terminal lipidation to increase antimicrobial activity and membrane perturbation: Structural insights into lipopolysaccharide binding.
J Colloid Interface Sci, 461, 2016
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2MWL
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