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8KC7
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BU of 8kc7 by Molmil
Rpd3S histone deacetylase complex
Descriptor: Chromatin modification-related protein EAF3, Histone deacetylase RPD3, Transcriptional regulatory protein RCO1, ...
Authors:Dong, S, Li, H, Wang, M, Rasheed, N, Zou, B, Gao, X, Guan, J, Li, W, Zhang, J, Wang, C, Zhou, N, Shi, X, Li, M, Zhou, M, Huang, J, Li, H, Zhang, Y, Wong, K.H, Zhang, X, Chao, W.C.H, He, J.
Deposit date:2023-08-06
Release date:2023-09-13
Last modified:2023-10-18
Method:ELECTRON MICROSCOPY (3.46 Å)
Cite:Structural basis of nucleosome deacetylation and DNA linker tightening by Rpd3S histone deacetylase complex.
Cell Res., 33, 2023
8KD4
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BU of 8kd4 by Molmil
Rpd3S in complex with nucleosome with H3K36MLA modification and 187bp DNA, class1
Descriptor: 187bp DNA, Chromatin modification-related protein EAF3, Histone H2A, ...
Authors:Dong, S, Li, H, Wang, M, Rasheed, N, Zou, B, Gao, X, Guan, J, Li, W, Zhang, J, Wang, C, Zhou, N, Shi, X, Li, M, Zhou, M, Huang, J, Li, H, Zhang, Y, Wong, K.H, Zhang, X, Chao, W.C.H, He, J.
Deposit date:2023-08-09
Release date:2023-09-13
Last modified:2023-10-11
Method:ELECTRON MICROSCOPY (2.93 Å)
Cite:Structural basis of nucleosome deacetylation and DNA linker tightening by Rpd3S histone deacetylase complex.
Cell Res., 33, 2023
8KD6
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BU of 8kd6 by Molmil
Rpd3S in complex with nucleosome with H3K36MLA modification and 187bp DNA, class3
Descriptor: 187bp DNA, Chromatin modification-related protein EAF3, Histone H2A, ...
Authors:Dong, S, Li, H, Wang, M, Rasheed, N, Zou, B, Gao, X, Guan, J, Li, W, Zhang, J, Wang, C, Zhou, N, Shi, X, Li, M, Zhou, M, Huang, J, Li, H, Zhang, Y, Wong, K.H, Zhang, X, Chao, W.C.H, He, J.
Deposit date:2023-08-09
Release date:2023-09-13
Last modified:2023-10-11
Method:ELECTRON MICROSCOPY (3.07 Å)
Cite:Structural basis of nucleosome deacetylation and DNA linker tightening by Rpd3S histone deacetylase complex.
Cell Res., 33, 2023
8KD7
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BU of 8kd7 by Molmil
Rpd3S in complex with nucleosome with H3K36MLA modification and 167bp DNA
Descriptor: 167bp DNA, Chromatin modification-related protein EAF3, Histone H2A, ...
Authors:Dong, S, Li, H, Wang, M, Rasheed, N, Zou, B, Gao, X, Guan, J, Li, W, Zhang, J, Wang, C, Zhou, N, Shi, X, Li, M, Zhou, M, Huang, J, Li, H, Zhang, Y, Wong, K.H, Chang, X, Chao, W.C.H, He, J.
Deposit date:2023-08-09
Release date:2023-09-13
Last modified:2023-10-11
Method:ELECTRON MICROSCOPY (3.09 Å)
Cite:Structural basis of nucleosome deacetylation and DNA linker tightening by Rpd3S histone deacetylase complex.
Cell Res., 33, 2023
1F04
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BU of 1f04 by Molmil
SOLUTION STRUCTURE OF OXIDIZED BOVINE MICROSOMAL CYTOCHROME B5 MUTANT (E44A, E48A, E56A, D60A) AND ITS INTERACTION WITH CYTOCHROME C
Descriptor: CYTOCHROME B5, PROTOPORPHYRIN IX CONTAINING FE
Authors:Wu, Y.B, Lu, J, Qian, C.M, Tang, W.X, Li, E.C, Wang, J.F, Wang, Y.H, Wang, W.H, Lu, J.X, Xie, Y, Huang, Z.X.
Deposit date:2000-05-14
Release date:2000-06-21
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of cytochrome b(5) mutant (E44/48/56A/D60A) and its interaction with cytochrome c.
Eur.J.Biochem., 268, 2001
5IUM
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BU of 5ium by Molmil
Crystal structure of phosphorylated DesKC
Descriptor: GLYCEROL, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ...
Authors:Trajtenberg, F, Buschiazzo, A.
Deposit date:2016-03-18
Release date:2016-12-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.162 Å)
Cite:Regulation of signaling directionality revealed by 3D snapshots of a kinase:regulator complex in action.
Elife, 5, 2016
5J4N
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BU of 5j4n by Molmil
Crystal structure of the L-arginine/agmatine antiporter AdiC in complex with agmatine at 2.6 Angstroem resolution
Descriptor: AGMATINE, Arginine/agmatine antiporter
Authors:Jeckelmann, J.M, Ilgue, H, Fotiadis, D.
Deposit date:2016-04-01
Release date:2016-08-31
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.594 Å)
Cite:Insights into the molecular basis for substrate binding and specificity of the wild-type L-arginine/agmatine antiporter AdiC.
Proc.Natl.Acad.Sci.USA, 113, 2016
1FMH
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BU of 1fmh by Molmil
NMR SOLUTION STRUCTURE OF A DESIGNED HETERODIMERIC LEUCINE ZIPPER
Descriptor: GENERAL CONTROL PROTEIN GCN4
Authors:Marti, D.N, Jelesarov, I, Bosshard, H.R.
Deposit date:2000-08-17
Release date:2000-11-01
Last modified:2021-11-03
Method:SOLUTION NMR
Cite:Interhelical ion pairing in coiled coils: solution structure of a heterodimeric leucine zipper and determination of pKa values of Glu side chains.
Biochemistry, 39, 2000
5T2C
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BU of 5t2c by Molmil
CryoEM structure of the human ribosome at 3.6 Angstrom resolution
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
Authors:Zhang, X, Lai, M, Zhou, Z.H.
Deposit date:2016-08-23
Release date:2017-01-25
Last modified:2023-08-16
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structures and stabilization of kinetoplastid-specific split rRNAs revealed by comparing leishmanial and human ribosomes.
Nat Commun, 7, 2016
8HEA
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BU of 8hea by Molmil
Esterase2 (EaEst2) from Exiguobacterium antarcticum
Descriptor: Thermostable carboxylesterase Est30
Authors:Hwang, J, Lee, J.H.
Deposit date:2022-11-08
Release date:2023-09-20
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Structural and Biochemical Insights into Bis(2-hydroxyethyl) Terephthalate Degrading Carboxylesterase Isolated from Psychrotrophic Bacterium Exiguobacterium antarcticum.
Int J Mol Sci, 24, 2023
8HGU
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BU of 8hgu by Molmil
Epoxide hydrolase from Bosea sp. PAMC 26642
Descriptor: Alpha/beta hydrolase
Authors:Lee, M.J, Hwang, J, Do, H, Lee, J.H.
Deposit date:2022-11-15
Release date:2023-11-22
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Structural insights into the distinct substrate preferences of two bacterial epoxide hydrolases.
Int.J.Biol.Macromol., 264, 2024
8HM5
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BU of 8hm5 by Molmil
Epoxide hydrolase from Caballeronia sordidicola PAMC 26510
Descriptor: Epoxide hydrolase
Authors:Hwang, J, Lee, M.J, Do, H, Lee, J.H.
Deposit date:2022-12-02
Release date:2023-12-06
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Structural insights into the distinct substrate preferences of two bacterial epoxide hydrolases.
Int.J.Biol.Macromol., 264, 2024
8IB0
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BU of 8ib0 by Molmil
The amyloid structure of mouse RIPK1 RHIM-containing domain by solid-state NMR
Descriptor: Receptor-interacting serine/threonine-protein kinase 1
Authors:Liu, J, Xialian, W.
Deposit date:2023-02-09
Release date:2023-03-22
Last modified:2024-05-15
Method:SOLID-STATE NMR
Cite:The amyloid structure of mouse RIPK1 RHIM-containing domain by solid-state NMR
To Be Published
4GSS
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BU of 4gss by Molmil
HUMAN GLUTATHIONE S-TRANSFERASE P1-1 Y108F MUTANT
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTATHIONE S-TRANSFERASE, S-HEXYLGLUTATHIONE
Authors:Oakley, A, Rossjohn, J, Parker, M.
Deposit date:1997-01-20
Release date:1998-01-28
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Multifunctional role of Tyr 108 in the catalytic mechanism of human glutathione transferase P1-1. Crystallographic and kinetic studies on the Y108F mutant enzyme.
Biochemistry, 36, 1997
3N9J
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BU of 3n9j by Molmil
Structure of human Glutathione Transferase Pi class in complex with Ethacraplatin
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ...
Authors:Parker, L.J, Parker, M.W.
Deposit date:2010-05-30
Release date:2011-05-11
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Studies of glutathione transferase P1-1 bound to a platinum(IV)-based anticancer compound reveal the molecular basis of its activation.
To be Published
3O76
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BU of 3o76 by Molmil
1.8 Angstroms molecular structure of mouse liver glutathione S-transferase mutant C47A complexed with S-(P-nitrobenzyl)glutathione
Descriptor: Glutathione S-transferase P 1, S-(P-NITROBENZYL)GLUTATHIONE
Authors:Canals, A, Coll, M.
Deposit date:2010-07-30
Release date:2011-06-15
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Site-directed mutagenesis of mouse glutathione transferase P1-1 unlocks masked cooperativity, introduces a novel mechanism for 'ping pong' kinetic behaviour, and provides further structural evidence for participation of a water molecule in proton abstraction from glutathione.
Febs J., 278, 2011
7T2Y
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BU of 7t2y by Molmil
X-ray structure of a designed cold unfolding four helix bundle
Descriptor: Designed cold unfolding four helix bundle
Authors:Harrison, J.S, Kuhlman, B, Szyperski, T, Premkumar, L, Maguire, J, Pulavarti, S, Yuen, S.
Deposit date:2021-12-06
Release date:2022-03-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:From Protein Design to the Energy Landscape of a Cold Unfolding Protein.
J.Phys.Chem.B, 126, 2022
4RKB
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BU of 4rkb by Molmil
Crystal structure of Staphylococcal nuclease variant Delta+PHS V66T/V99T at cryogenic temperature
Descriptor: CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease
Authors:Caro, J.A, Schlessman, J.L, Garcia-Moreno E, B.
Deposit date:2014-10-12
Release date:2014-11-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Cavities in proteins
to be published
2QF7
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BU of 2qf7 by Molmil
Crystal structure of a complete multifunctional pyruvate carboxylase from Rhizobium etli
Descriptor: CHLORIDE ION, COENZYME A, FORMIC ACID, ...
Authors:St Maurice, M, Surinya, K.H, Rayment, I.
Deposit date:2007-06-27
Release date:2007-09-04
Last modified:2012-02-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Domain architecture of pyruvate carboxylase, a biotin-dependent multifunctional enzyme
Science, 317, 2007
4RUV
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BU of 4ruv by Molmil
Crystal structure of thioredoxin 2 from Staphylococcus aureus NCTC8325
Descriptor: Thioredoxin
Authors:Bose, M, Biswas, R, Roychowdhury, A, Bhattacharyya, S, Ghosh, A.K, Das, A.K.
Deposit date:2014-11-22
Release date:2015-12-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Elucidation of the mechanism of disulfide exchange between staphylococcal thioredoxin2 and thioredoxin reductase2: A structural insight.
Biochimie, 160, 2019
2R5O
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BU of 2r5o by Molmil
Crystal structure of the C-terminal domain of wzt
Descriptor: CHLORIDE ION, Putative ATP binding component of ABC-transporter, SODIUM ION, ...
Authors:Kimber, M.S, Cuthbertson, L, Whitfield, C.
Deposit date:2007-09-04
Release date:2007-12-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Substrate binding by a bacterial ABC transporter involved in polysaccharide export.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2RET
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BU of 2ret by Molmil
The crystal structure of a binary complex of two pseudopilins: EpsI and EpsJ from the Type 2 Secretion System of Vibrio vulnificus
Descriptor: CHLORIDE ION, EpsJ, Pseudopilin EpsI, ...
Authors:Yanez, M.E, Korotkov, K.V, Abendroth, J, Hol, W.G.J.
Deposit date:2007-09-27
Release date:2008-02-05
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:The crystal structure of a binary complex of two pseudopilins: EpsI and EpsJ from the type 2 secretion system of Vibrio vulnificus.
J.Mol.Biol., 375, 2008
7TQL
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BU of 7tql by Molmil
CryoEM structure of the human 40S small ribosomal subunit in complex with translation initiation factors eIF1A and eIF5B.
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
Authors:Lapointe, C.P, Grosely, R, Sokabe, M, Alvarado, C, Wang, J, Montabana, E, Villa, N, Shin, B, Dever, T, Fraser, C, Fernandez, I.S, Puglisi, J.D.
Deposit date:2022-01-26
Release date:2022-04-27
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:eIF5B and eIF1A reorient initiator tRNA to allow ribosomal subunit joining.
Nature, 607, 2022
4UG0
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BU of 4ug0 by Molmil
STRUCTURE OF THE HUMAN 80S RIBOSOME
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S RIBOSOMAL PROTEIN, ...
Authors:Khatter, H, Myasnikov, A.G, Natchiar, S.K, Klaholz, B.P.
Deposit date:2015-03-20
Release date:2015-06-10
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure of the human 80S ribosome
NATURE, 520, 2015
4U79
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BU of 4u79 by Molmil
Crystal structure of human JNK3 in complex with a benzenesulfonamide inhibitor.
Descriptor: Mitogen-activated protein kinase 10, N-{4-[(3-{2-[(trans-4-aminocyclohexyl)amino]pyrimidin-4-yl}pyridin-2-yl)oxy]naphthalen-1-yl}benzenesulfonamide
Authors:Mohr, C.
Deposit date:2014-07-30
Release date:2014-10-08
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Unfolded Protein Response in Cancer: IRE1 alpha Inhibition by Selective Kinase Ligands Does Not Impair Tumor Cell Viability.
Acs Med.Chem.Lett., 6, 2015

221051

数据于2024-06-12公开中

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