PDB: 30760 resultsInfo pagesStatus searchChemie searchBIRD

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6D8S	NMR solution structure of tamapin, mutant K27E Descriptor: Potassium channel toxin alpha-KTx 5.4 Authors: del Rio Portilla, F, Melchor Meneses, C.M, Titaux Delgado, G.A, Mayorga Flores, M. Deposit date: 2018-04-26 Release date: 2019-05-01 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Novel Blocker of Onco SK3 Channels Derived from Scorpion Toxin Tamapin and Active against Migration of Cancer Cells Acs Med.Chem.Lett., 2020
6D93	NMR solution structure of tamapin, mutant Y31A Descriptor: Potassium channel toxin alpha-KTx 5.4 Authors: del Rio Portilla, F, Melchor Meneses, C.M, Titaux Delgado, G.A, Mayorga Flores, M. Deposit date: 2018-04-27 Release date: 2019-05-01 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Novel Blocker of Onco SK3 Channels Derived from Scorpion Toxin Tamapin and Active against Migration of Cancer Cells Acs Med.Chem.Lett., 2020
4ZRB	Crystal Structure of Hypothetical Thioesterase Protein SP_1851 with Coenzyme A from Streptococcus pneumoniae TIGR4 Descriptor: COENZYME A, Hypothetical Thioesterase Protein SP_1851 Authors: Khandokar, Y.B, Srivastava, P, Forwood, J.K. Deposit date: 2015-05-12 Release date: 2015-05-27 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural and Functional Characterization of the PaaI Thioesterase from Streptococcus pneumoniae Reveals a Dual Specificity for Phenylacetyl-CoA and Medium-chain Fatty Acyl-CoAs and a Novel CoA-induced Fit Mechanism. J.Biol.Chem., 291, 2016
7MPZ	HNH Nuclease Domain from G. stearothermophilus Cas9 Descriptor: CRISPR-associated endonuclease Cas9 Authors: D'Ordine, A.M, Belato, H.B, Lisi, G.P, Jogl, G. Deposit date: 2021-05-05 Release date: 2021-12-22 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.04 Å) Cite: Structural and dynamic insights into the HNH nuclease of divergent Cas9 species. J.Struct.Biol., 214, 2021
5A07	X-ray structure of the mannosyltransferase Ktr4p from S. cerevisiae in complex with GDP Descriptor: ACETATE ION, GUANOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ... Authors: Possner, D.D.D, Guy, J.E. Deposit date: 2015-04-17 Release date: 2015-08-26 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structure of the Glycosyltransferase Ktr4P from Saccharomyces Cerevisiae Plos One, 10, 2015
4ZTY	Neurospora crassa cobalamin-independent methionine synthase complexed with Cd2+ Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CADMIUM ION, Cobalamin-Independent Methionine synthase, ... Authors: Wheatley, R.W, Ng, K.K, Kapoor, M. Deposit date: 2015-05-15 Release date: 2015-12-09 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.88 Å) Cite: Fungal cobalamin-independent methionine synthase: Insights from the model organism, Neurospora crassa. Arch.Biochem.Biophys., 590, 2015
7MWI	Crystal structure of human BAZ2A Descriptor: Bromodomain adjacent to zinc finger domain protein 2A, UNKNOWN ATOM OR ION Authors: Liu, K, Dong, A, Li, Y, Loppnau, P, Edwards, A.M, Arrowsmith, C.H, Min, J, Structural Genomics Consortium (SGC) Deposit date: 2021-05-17 Release date: 2021-12-29 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural basis of the TAM domain of BAZ2A in binding to DNA or RNA independent of methylation status. J.Biol.Chem., 297, 2021
4ZW5	X-ray crystal structure of PfA-M1 in complex with hydroxamic acid-based inhibitor 9f Descriptor: M1 family aminopeptidase, MAGNESIUM ION, ZINC ION, ... Authors: Drinkwater, N, McGowan, S. Deposit date: 2015-05-19 Release date: 2016-03-30 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions. Eur.J.Med.Chem., 110, 2016
4ZX5	X-ray crystal structure of PfA-M1 in complex with hydroxamic acid-based inhibitor 10q Descriptor: DIMETHYL SULFOXIDE, GLYCEROL, M1 family aminopeptidase, ... Authors: Drinkwater, N, McGowan, S. Deposit date: 2015-05-20 Release date: 2016-03-30 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions. Eur.J.Med.Chem., 110, 2016
7MQY	Zebrafish CNTN4 APLP2 complex Descriptor: Fusion protein of CNTN4 and APLP2 Authors: Bouyain, S, Karuppan, S.J. Deposit date: 2021-05-07 Release date: 2022-01-05 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.46 Å) Cite: Members of the vertebrate contactin and amyloid precursor protein families interact through a conserved interface. J.Biol.Chem., 298, 2021
7M5C	Crystal Structure of human BAK in complex with WT BAK BH3 peptide Descriptor: Bcl-2 homologous antagonist/killer, COPPER (II) ION, SULFATE ION Authors: Singh, G, Aggarwal, A, Moldoveanu, T. Deposit date: 2021-03-23 Release date: 2022-01-12 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (3.06 Å) Cite: Structural basis of BAK activation in mitochondrial apoptosis initiation. Nat Commun, 13, 2022
4ZRW	Structure of cow mincle complexed with trehalose Descriptor: CALCIUM ION, alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose, mincle protein Authors: Feinberg, H, Rambaruth, N.D.S, Taylor, M.E, Drickamer, K, Weis, W.I. Deposit date: 2015-05-12 Release date: 2016-05-25 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Binding Sites for Acylated Trehalose Analogs of Glycolipid Ligands on an Extended Carbohydrate Recognition Domain of the Macrophage Receptor Mincle. J.Biol.Chem., 291, 2016
7MRO	Zebrafish CNTN4 FN1-FN3 domains Descriptor: Contactin-4 Authors: Bouyain, S, Karuppan, S.J. Deposit date: 2021-05-07 Release date: 2022-01-05 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.87 Å) Cite: Members of the vertebrate contactin and amyloid precursor protein families interact through a conserved interface. J.Biol.Chem., 298, 2021
7MRZ	Structure of GDF11 bound to fused ActRIIB-ECD and Alk4-ECD with Anti-ActRIIB Fab fragment Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Activin receptor type-2B,Activin receptor type-1B, Fab Heavy Chain, ... Authors: Goebel, E.J, Kattamuri, C, Gipson, G.R, Thompson, T.B. Deposit date: 2021-05-10 Release date: 2022-01-19 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (3 Å) Cite: Structures of activin ligand traps using natural sets of type I and type II TGF beta receptors. Iscience, 25, 2022
7MRS	Zebrafish CNTN4 APPb complex Descriptor: Amyloid-beta A4 protein, Contactin-4 Authors: Bouyain, S, Karuppan, S.J. Deposit date: 2021-05-09 Release date: 2022-01-05 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.93 Å) Cite: Members of the vertebrate contactin and amyloid precursor protein families interact through a conserved interface. J.Biol.Chem., 298, 2021
7MRM	Chicken CNTN3 APP complex Descriptor: Fusion protein of Chicken CNTN3 FN1-FN2 domains and Amyloid-beta A4 protein,Amyloid-beta A4 protein, SULFATE ION Authors: Bouyain, S, Karuppan, S.J. Deposit date: 2021-05-07 Release date: 2022-01-05 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Members of the vertebrate contactin and amyloid precursor protein families interact through a conserved interface. J.Biol.Chem., 298, 2021
7MRK	Chicken CNTN4 APP complex Descriptor: Amyloid-beta A4 protein, Contactin-4, DI(HYDROXYETHYL)ETHER Authors: Bouyain, S, Karuppan, S.J. Deposit date: 2021-05-07 Release date: 2022-01-05 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Members of the vertebrate contactin and amyloid precursor protein families interact through a conserved interface. J.Biol.Chem., 298, 2021
7MWT	Structure of the E. coli PutA proline dehydrogenase domain (residues 86-630) complexed with 1,1-Cyclobutanedicarboxylate Descriptor: Bifunctional protein PutA, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, ... Authors: Tanner, J.J, Bogner, A.N. Deposit date: 2021-05-17 Release date: 2022-01-19 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.19 Å) Cite: Structure-affinity relationships of reversible proline analog inhibitors targeting proline dehydrogenase. Org.Biomol.Chem., 20, 2022
7MRN	Mouse CNTN5 APP complex Descriptor: Contactin-5, N-APP Authors: Bouyain, S, Karuppan, S.J. Deposit date: 2021-05-07 Release date: 2022-01-05 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Members of the vertebrate contactin and amyloid precursor protein families interact through a conserved interface. J.Biol.Chem., 298, 2021
4ZTJ	Crystal Structure of the Prototype Foamy Virus Intasome with a 2-Pyridinone Aminal Inhibitor Descriptor: (1R,2S,5R)-8'-(3-chloro-4-fluorobenzyl)-6'-hydroxy-1-(hydroxymethyl)-2'-methyl-9',10'-dihydro-2'H-spiro[bicyclo[3.1.0]hexane-2,3'-imidazo[5,1-a][2,6]naphthyridine]-1',5',7'(8'H)-trione, DNA (5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*CP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*GP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP*AP*CP*A)-3'), ... Authors: Klein, D.J, Patel, S. Deposit date: 2015-05-14 Release date: 2015-10-07 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.67 Å) Cite: Discovery of 2-Pyridinone Aminals: A Prodrug Strategy to Advance a Second Generation of HIV-1 Integrase Strand Transfer Inhibitors. J.Med.Chem., 58, 2015
7MWU	Structure of the E. coli PutA proline dehydrogenase domain (residues 86-630) complexed with cyclobutanecarboxylic acid Descriptor: Bifunctional protein PutA, FLAVIN-ADENINE DINUCLEOTIDE, PENTAETHYLENE GLYCOL, ... Authors: Tanner, J.J, Bogner, A.N. Deposit date: 2021-05-17 Release date: 2022-01-19 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.69 Å) Cite: Structure-affinity relationships of reversible proline analog inhibitors targeting proline dehydrogenase. Org.Biomol.Chem., 20, 2022
4ZV7	Crystal structure of hexagonal form of lipase B from Candida antarctica Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Lipase B Authors: Strzelczyk, P, Blaszczyk, J, Bujacz, G. Deposit date: 2015-05-18 Release date: 2016-01-13 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal and molecular structure of hexagonal form of lipase B from Candida antarctica. Acta Biochim.Pol., 63, 2016
7MLP	Crystal structure of ricin A chain in complex with 5-(2,6-dimethylphenyl)thiophene-2-carboxylic acid Descriptor: 1,2-ETHANEDIOL, 5-(2,6-dimethylphenyl)thiophene-2-carboxylic acid, Ricin, ... Authors: Harijan, R.K, Li, X.P, Cao, B, Augeri, D, Bonanno, J.B, Almo, S.C, Tumer, N.E, Schramm, V.L. Deposit date: 2021-04-28 Release date: 2022-02-09 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.78 Å) Cite: Synthesis and Structural Characterization of Ricin Inhibitors Targeting Ribosome Binding Using Fragment-Based Methods and Structure-Based Design. J.Med.Chem., 64, 2021
7MP3	Grb7-SH2 domain in complex with bicyclic peptide B8 Descriptor: Growth factor receptor-bound protein 7, bicyclic peptide B8 Authors: Colson, R, Wilce, M.C.J, Wilce, J.A. Deposit date: 2021-05-04 Release date: 2022-02-02 Last modified: 2024-04-17 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Enhancing the Bioactivity of Bicyclic Peptides Targeted to Grb7-SH2 by Restoring Cell Permeability. Biomedicines, 10, 2022
4ZW6	X-ray crystal structure of PfA-M1 in complex with hydroxamic acid-based inhibitor 9q Descriptor: DIMETHYL SULFOXIDE, GLYCEROL, M1 family aminopeptidase, ... Authors: Drinkwater, N, McGowan, S. Deposit date: 2015-05-19 Release date: 2016-03-30 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions. Eur.J.Med.Chem., 110, 2016

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