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3MUM
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BU of 3mum by Molmil
Crystal Structure of the G20A mutant c-di-GMP riboswith bound to c-di-GMP
Descriptor: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), G20A mutant c-di-GMP Riboswitch, MAGNESIUM ION, ...
Authors:Strobel, S.A, Smith, K.D.
Deposit date:2010-05-03
Release date:2010-08-25
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural and biochemical determinants of ligand binding by the c-di-GMP riboswitch .
Biochemistry, 49, 2010
3TYQ
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BU of 3tyq by Molmil
SAR development and discovery of potent indole-based inhibitors of the hepatitis c virus NS5B polymerase
Descriptor: 5-ethyl-1-(2-fluoro-5-nitrobenzyl)-3-(2-oxo-1,2-dihydropyridin-3-yl)-1H-indole-2-carboxylic acid, PHOSPHATE ION, RNA-directed RNA polymerase
Authors:Lesburg, C.A, Chen, K.X.
Deposit date:2011-09-26
Release date:2012-02-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:A Novel Class of Highly Potent Irreversible Hepatitis C Virus NS5B Polymerase Inhibitors.
J.Med.Chem., 55, 2012
4FOK
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BU of 4fok by Molmil
1.8 A Crystal structure of the FimX EAL domain in complex with c-diGMP
Descriptor: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), FimX, GLYCEROL
Authors:Farah, C.S, Guzzo, C.R.
Deposit date:2012-06-20
Release date:2013-03-27
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of the PilZ-FimXEAL-c-di-GMP Complex Responsible for the Regulation of Bacterial Type IV Pilus Biogenesis.
J.Mol.Biol., 425, 2013
3MXH
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BU of 3mxh by Molmil
Native structure of a c-di-GMP riboswitch from V. cholerae
Descriptor: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), MAGNESIUM ION, U1 small nuclear ribonucleoprotein A, ...
Authors:Strobel, S.A, Smith, K.D.
Deposit date:2010-05-07
Release date:2010-08-25
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and biochemical determinants of ligand binding by the c-di-GMP riboswitch .
Biochemistry, 49, 2010
4RT0
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BU of 4rt0 by Molmil
Structure of the Alg44 PilZ domain from Pseudomonas aeruginosa PAO1 in complex with c-di-GMP
Descriptor: 1,2-ETHANEDIOL, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Alginate biosynthesis protein Alg44
Authors:Whitfield, G.B, Whitney, J.C.
Deposit date:2014-11-12
Release date:2015-04-08
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Dimeric c-di-GMP Is Required for Post-translational Regulation of Alginate Production in Pseudomonas aeruginosa.
J.Biol.Chem., 290, 2015
1JCI
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BU of 1jci by Molmil
Stabilization of the Engineered Cation-binding Loop in Cytochrome c Peroxidase (CcP)
Descriptor: Cytochrome C Peroxidase, POTASSIUM ION, PROTOPORPHYRIN IX CONTAINING FE
Authors:Bhaskar, B, Bonagura, C.A, Li, H, Poulos, T.L.
Deposit date:2001-06-09
Release date:2002-03-06
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Cation-induced stabilization of the engineered cation-binding loop in cytochrome c peroxidase (CcP).
Biochemistry, 41, 2002
1E85
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BU of 1e85 by Molmil
Cytochrome c' from Alcaligenes xylosoxidans - reduced structure with NO bound to proximal side of heme
Descriptor: CYTOCHROME C', HEME C, NITRIC OXIDE
Authors:Lawson, D.M, Stevenson, C.E.M, Andrew, C.R, Eady, R.R.
Deposit date:2000-09-15
Release date:2000-11-06
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Unprecedented Proximal Binding of Nitric Oxide to Heme: Implications for Guanylate Cyclase.
Embo J., 19, 2000
3MUT
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BU of 3mut by Molmil
Crystal Structure of the G20A/C92U mutant c-di-GMP riboswith bound to c-di-GMP
Descriptor: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), G20A/C92U mutant c-di-GMP riboswitch, MAGNESIUM ION, ...
Authors:Strobel, S.A, Smith, K.D.
Deposit date:2010-05-03
Release date:2010-08-25
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural and biochemical determinants of ligand binding by the c-di-GMP riboswitch .
Biochemistry, 49, 2010
1G5Z
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BU of 1g5z by Molmil
CRYSTAL STRUCTURE OF LYME DISEASE ANTIGEN OUTER SURFACE PROTEIN C (OSPC) FROM BORRELIA BURGDORFERI STRAIN N40
Descriptor: OUTER SURFACE PROTEIN C
Authors:Eicken, C, Sharma, V, Klabunde, T, Owens, R.T, Pikas, D.S, Hook, M, Sacchettini, J.C.
Deposit date:2000-11-02
Release date:2001-04-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Crystal structure of Lyme disease antigen outer surface protein C from Borrelia burgdorferi.
J.Biol.Chem., 276, 2001
1TBN
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BU of 1tbn by Molmil
NMR STRUCTURE OF A PROTEIN KINASE C-G PHORBOL-BINDING DOMAIN, MINIMIZED AVERAGE STRUCTURE
Descriptor: PROTEIN KINASE C, GAMMA TYPE, ZINC ION
Authors:Xu, R.X, Pawelczyk, T, Xia, T, Brown, S.C.
Deposit date:1997-04-15
Release date:1998-04-29
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:NMR structure of a protein kinase C-gamma phorbol-binding domain and study of protein-lipid micelle interactions.
Biochemistry, 36, 1997
1F1C
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BU of 1f1c by Molmil
CRYSTAL STRUCTURE OF CYTOCHROME C549
Descriptor: CYTOCHROME C549, HEME C
Authors:Kerfeld, C.A, Sawaya, M.R, Yeates, T.O, Krogmann, D.W.
Deposit date:2000-05-18
Release date:2001-08-08
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of cytochrome c-549 and cytochrome c6 from the cyanobacterium Arthrospira maxima.
Biochemistry, 40, 2001
1TBO
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BU of 1tbo by Molmil
NMR STRUCTURE OF A PROTEIN KINASE C-G PHORBOL-BINDING DOMAIN, 30 STRUCTURES
Descriptor: PROTEIN KINASE C, GAMMA TYPE, ZINC ION
Authors:Xu, R.X, Pawelczyk, T, Xia, T, Brown, S.C.
Deposit date:1997-04-15
Release date:1998-04-29
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:NMR structure of a protein kinase C-gamma phorbol-binding domain and study of protein-lipid micelle interactions.
Biochemistry, 36, 1997
1INJ
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BU of 1inj by Molmil
CRYSTAL STRUCTURE OF THE APO FORM OF 4-DIPHOSPHOCYTIDYL-2-C-METHYLERYTHRITOL (CDP-ME) SYNTHETASE (YGBP) INVOLVED IN MEVALONATE INDEPENDENT ISOPRENOID BIOSYNTHESIS
Descriptor: 4-DIPHOSPHOCYTIDYL-2-C-METHYLERYTHRITOL SYNTHETASE, CALCIUM ION
Authors:Richard, S.B, Bowman, M.E, Kwiatkowski, W, Kang, I, Chow, C, Lillo, A, Cane, D.E, Noel, J.P.
Deposit date:2001-05-14
Release date:2001-07-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structure of 4-diphosphocytidyl-2-C- methylerythritol synthetase involved in mevalonate- independent isoprenoid biosynthesis.
Nat.Struct.Biol., 8, 2001
3TOR
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BU of 3tor by Molmil
Crystal structure of Escherichia coli NrfA with Europium bound
Descriptor: CALCIUM ION, Cytochrome c nitrite reductase, EUROPIUM ION, ...
Authors:Lockwood, C.W.J, Clarke, T.A, Butt, J.N, Hemmings, A.M, Richardson, D.J.
Deposit date:2011-09-06
Release date:2011-12-07
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Characterization of the active site and calcium binding in cytochrome c nitrite reductases.
Biochem.Soc.Trans., 39, 2011
1E84
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BU of 1e84 by Molmil
Cytochrome c' from Alcaligenes xylosoxidans - reduced structure
Descriptor: CYTOCHROME C', HEME C
Authors:Lawson, D.M, Stevenson, C.E.M, Andrew, C.R, Eady, R.R.
Deposit date:2000-09-15
Release date:2000-11-06
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Unprecedented Proximal Binding of Nitric Oxide to Heme: Implications for Guanylate Cyclase
Embo J., 19, 2000
1E86
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BU of 1e86 by Molmil
Cytochrome c' from Alcaligenes xylosoxidans - reduced structure with CO bound to distal side of heme
Descriptor: CARBON MONOXIDE, CYTOCHROME C', HEME C
Authors:Lawson, D.M, Stevenson, C.E.M, Andrew, C.R, Eady, R.R.
Deposit date:2000-09-15
Release date:2000-11-06
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Unprecedented Proximal Binding of Nitric Oxide to Heme: Implications for Guanylate Cyclase
Embo J., 19, 2000
1I6E
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BU of 1i6e by Molmil
SOLUTION STRUCTURE OF THE FUNCTIONAL DOMAIN OF PARACOCCUS DENITRIFICANS CYTOCHROME C552 IN THE OXIDIZED STATE
Descriptor: CYTOCHROME C552, HEME C
Authors:Reincke, B, Perez, C, Pristovsek, P, Luecke, C, Ludwig, C, Loehr, F, Rogov, V.V, Ludwig, B, Rueterjans, H.
Deposit date:2001-03-02
Release date:2001-10-17
Last modified:2024-10-30
Method:SOLUTION NMR
Cite:Solution structure and dynamics of the functional domain of Paracoccus denitrificans cytochrome c(552) in both redox states.
Biochemistry, 40, 2001
2YAD
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BU of 2yad by Molmil
BRICHOS domain of Surfactant protein C precursor protein
Descriptor: SURFACTANT PROTEIN C BRICHOS DOMAIN
Authors:Askarieh, G, Siponen, M.I, Willander, H, Landreh, M, Westermark, P, Nordling, K, Keranen, H, Hermansson, E, Hamvas, A, Nogee, L.M, Bergman, T, Saenz, A, Casals, C, Aqvist, J, Jornvall, H, Presto, J, Johansson, J, Arrowsmith, C.H, Bountra, C, Collins, R, Edwards, A.M, Ekblad, T, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Karlberg, T, Kol, S, Kotenyova, T, Kouznetsova, E, Moche, M, Nyman, T, Nordlund, P, Persson, C, Schuler, H, Thorsell, A.G, Tresaugues, L, van den Berg, S, Wahlberg, E, Weigelt, J, Welin, M, Berglund, H, Knight, S.D.
Deposit date:2011-02-18
Release date:2012-02-15
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:High Resolution Structure of a Bricos Domain and its Implications for Anti-Amyloid Chaperone Activity on Lung Surgactant Protein C.
Proc.Natl.Acad.Sci.USA, 109, 2012
2BRK
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BU of 2brk by Molmil
Crystal structure of Hepatitis C virus polymerase in complex with an allosteric inhibitor (compound 1)
Descriptor: 3-CYCLOHEXYL-1-(2-MORPHOLIN-4-YL-2-OXOETHYL)-2-PHENYL-1H-INDOLE-6-CARBOXYLIC ACID, MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE
Authors:Di Marco, S, Volpari, C, Carfi, A.
Deposit date:2005-05-06
Release date:2005-06-14
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Interdomain Communication in Hepatitis C Virus Polymerase Abolished by Small-Molecule Inhibitors Bound to a Novel Allosteric Site
J.Biol.Chem., 280, 2005
2BRL
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BU of 2brl by Molmil
Crystal structure of Hepatitis C virus polymerase in complex with an allosteric inhibitor (compound 2)
Descriptor: 3-CYCLOHEXYL-1-(2-{METHYL[(1-METHYLPIPERIDIN-3-YL)METHYL]AMINO}-2-OXOETHYL)-2-PHENYL-1H-INDOLE-6-CARBOXYLIC ACID, MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE
Authors:Di Marco, S, Volpari, C, Carfi, A.
Deposit date:2005-05-06
Release date:2005-06-14
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Interdomain Communication in Hepatitis C Virus Polymerase Abolished by Small-Molecule Inhibitors Bound to a Novel Allosteric Site
J.Biol.Chem., 280, 2005
1W2A
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BU of 1w2a by Molmil
Deacetoxycephalosporin C synthase (with his-tag) complexed with Fe(II) and ethylene glycol
Descriptor: 1,2-ETHANEDIOL, DEACETOXYCEPHALOSPORIN C SYNTHASE, FE (III) ION
Authors:Oster, L.M, Terwisscha Van Scheltinga, A.C, Valegard, K, Mackenzie Hose, A, Dubus, A, Hajdu, J, Andersson, I.
Deposit date:2004-07-01
Release date:2004-09-30
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Conformational Flexibility of the C Terminus with Implications for Substrate Binding and Catalysis Revealed in a New Crystal Form of Deacetoxycephalosporin C Synthase
J.Mol.Biol., 343, 2004
1I6D
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BU of 1i6d by Molmil
SOLUTION STRUCTURE OF THE FUNCTIONAL DOMAIN OF PARACOCCUS DENITRIFICANS CYTOCHROME C552 IN THE REDUCED STATE
Descriptor: CYTOCHROME C552, HEME C
Authors:Reincke, B, Perez, C, Pristovsek, P, Luecke, C, Ludwig, C, Loehr, F, Rogov, V.V, Ludwig, B, Rueterjans, H.
Deposit date:2001-03-02
Release date:2001-10-17
Last modified:2024-10-16
Method:SOLUTION NMR
Cite:Solution structure and dynamics of the functional domain of Paracoccus denitrificans cytochrome c(552) in both redox states.
Biochemistry, 40, 2001
1W28
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BU of 1w28 by Molmil
Conformational flexibility of the C-terminus with implications for substrate binding and catalysis in a new crystal form of deacetoxycephalosporin C synthase
Descriptor: DEACETOXYCEPHALOSPORIN C SYNTHASE
Authors:Oster, L.M, Terwisscha Van Scheltinga, A.C, Valegard, K, Mackenzie Hose, A, Dubus, A, Hajdu, J, Andersson, I.
Deposit date:2004-06-30
Release date:2004-09-30
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Conformational Flexibility of the C Terminus with Implications for Substrate Binding and Catalysis Revealed in a New Crystal Form of Deacetoxycephalosporin C Synthase
J.Mol.Biol., 343, 2004
2X07
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BU of 2x07 by Molmil
cytochrome c peroxidase: engineered ascorbate binding site
Descriptor: Cytochrome c peroxidase, mitochondrial, PROTOPORPHYRIN IX CONTAINING FE
Authors:Murphy, E.J, Metcalfe, C.L, Gumiero, A, Raven, E.L, Moody, P.C.E.
Deposit date:2009-12-07
Release date:2010-11-10
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Engineering the substrate specificity and reactivity of a heme protein: creation of an ascorbate binding site in cytochrome c peroxidase.
Biochemistry, 47, 2008
1GGQ
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BU of 1ggq by Molmil
OUTER SURFACE PROTEIN C (OSPC) OF BORRELIA BURGDORFERI STRAIN B31
Descriptor: MAGNESIUM ION, OUTER SURFACE PROTEIN C
Authors:Dunn, J.J, Lawson, C.L.
Deposit date:2000-09-14
Release date:2001-03-14
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Crystal structure of outer surface protein C (OspC) from the Lyme disease spirochete, Borrelia burgdorferi.
EMBO J., 20, 2001

238582

数据于2025-07-09公开中

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