7TW8
 
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4X3Q
 | | Crystal structure of S-adenosylmethionine-dependent methyltransferase SibL in complex with SAH | | Descriptor: | S-ADENOSYL-L-HOMOCYSTEINE, SibL | | Authors: | liu, J.S, Chen, S.C, Yang, C.S, Huang, C.H, Chen, Y. | | Deposit date: | 2014-12-01 | | Release date: | 2015-11-25 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.586 Å) | | Cite: | Crystal structure of S-adenosylmethionine-dependent methyltransferase SibL in complex with SAH
To Be Published, 2015
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8W2Q
 | | BsaXI-DNA complex II | | Descriptor: | DNA (41-MER), RM.BsaXI, S-ADENOSYL-L-HOMOCYSTEINE, ... | | Authors: | Shen, B.W, Stoddard, B.L, Xu, S. | | Deposit date: | 2024-02-21 | | Release date: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (3.06 Å) | | Cite: | Structural and biochemical analysis of subunit assembly, DNA recognition and cleavage by a Type IIB restriction-modification enzyme: BsaXI
To Be Published
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6BRR
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2VE3
 | | Retinoic acid bound cyanobacterial CYP120A1 | | Descriptor: | PROTOPORPHYRIN IX CONTAINING FE, PUTATIVE CYTOCHROME P450 120, RETINOIC ACID | | Authors: | Kuhnel, K, Ke, N, Sligar, S.G, Schuler, M.A, Schlichting, I. | | Deposit date: | 2007-10-15 | | Release date: | 2008-04-29 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal Structures of Substrate-Free and Retinoic Acid-Bound Cyanobacterial Cytochrome P450 Cyp120A1.
Biochemistry, 47, 2008
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3CIM
 | | Carboxysome shell protein, CcmK2 C-terminal deletion mutant | | Descriptor: | Carbon dioxide-concentrating mechanism protein ccmK homolog 2, GLYCEROL, SULFATE ION | | Authors: | Tanaka, S, Sawaya, M.R, Yeates, T.O. | | Deposit date: | 2008-03-11 | | Release date: | 2009-02-03 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Insights from multiple structures of the shell proteins from the beta-carboxysome.
Protein Sci., 18, 2009
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8RDL
 | | Xenorhabdin methyltransferase XrdM with SAH | | Descriptor: | S-ADENOSYL-L-HOMOCYSTEINE, ToxA protein | | Authors: | Huber, E.M, Groll, M. | | Deposit date: | 2023-12-08 | | Release date: | 2024-10-16 | | Last modified: | 2024-12-04 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Isofunctional but Structurally Different Methyltransferases for Dithiolopyrrolone Diversification.
Angew.Chem.Int.Ed.Engl., 63, 2024
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8RBK
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8RR3
 | | Human mitochondrial RNase Z complex with ELAC2-D550N catalytic mutant and tRNA-Gln precursor (Composite model) | | Descriptor: | 3-hydroxyacyl-CoA dehydrogenase type-2, Human mitochondrial tRNA-Gln precursor with 3' trailer RNA, S-ADENOSYL-L-HOMOCYSTEINE, ... | | Authors: | Bhatta, A, Yu, R.D, Kuhle, B, Hillen, H.S. | | Deposit date: | 2024-01-22 | | Release date: | 2025-01-08 | | Last modified: | 2025-04-23 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Molecular basis of human nuclear and mitochondrial tRNA 3' processing.
Nat.Struct.Mol.Biol., 32, 2025
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8RR1
 | | Human mitochondrial RNase Z complex with ELAC2-D550N catalytic mutant and tRNA-Tyr precursor (Composite model) | | Descriptor: | 3-hydroxyacyl-CoA dehydrogenase type-2, Human mitochondrial tRNA-Tyr precursor with 3' trailer, S-ADENOSYL-L-HOMOCYSTEINE, ... | | Authors: | Bhatta, A, Yu, R.D, Kuhle, B, Hillen, H.S. | | Deposit date: | 2024-01-22 | | Release date: | 2025-01-08 | | Last modified: | 2025-04-23 | | Method: | ELECTRON MICROSCOPY (2.93 Å) | | Cite: | Molecular basis of human nuclear and mitochondrial tRNA 3' processing.
Nat.Struct.Mol.Biol., 32, 2025
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8RR4
 | | Human mitochondrial RNase Z complex with ELAC2-D550N catalytic mutant with ordered flexible arm and tRNA-Tyr precursor - (Composite model) | | Descriptor: | 3-hydroxyacyl-CoA dehydrogenase type-2, Human mitochondria tRNA-Tyr precursor with 3' trailer, S-ADENOSYL-L-HOMOCYSTEINE, ... | | Authors: | Bhatta, A, Yu, R.D, Kuhle, B, Hillen, H.S. | | Deposit date: | 2024-01-22 | | Release date: | 2025-01-08 | | Last modified: | 2025-04-23 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Molecular basis of human nuclear and mitochondrial tRNA 3' processing.
Nat.Struct.Mol.Biol., 32, 2025
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5DNK
 | | The structure of PKMT1 from Rickettsia prowazekii in complex with AdoHcy | | Descriptor: | S-ADENOSYL-L-HOMOCYSTEINE, protein lysine methyltransferase 1 | | Authors: | Noinaj, N, Abeykoon, A, He, Y, Yang, D.C, Buchanan, S.K. | | Deposit date: | 2015-09-10 | | Release date: | 2016-08-10 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural Insights into Substrate Recognition and Catalysis in Outer Membrane Protein B (OmpB) by Protein-lysine Methyltransferases from Rickettsia.
J.Biol.Chem., 291, 2016
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6MJG
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8GZH
 | | Cryo-EM structure of Synechocystis sp. PCC 6803 CTP-bound RPitc | | Descriptor: | CYTIDINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | Authors: | You, L.L, Shen, L.Q, Zhang, Y. | | Deposit date: | 2022-09-27 | | Release date: | 2023-04-19 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (2.96 Å) | | Cite: | An SI3-sigma arch stabilizes cyanobacteria transcription initiation complex.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8GZG
 | | Cryo-EM structure of Synechocystis sp. PCC 6803 RPitc | | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | Authors: | Shen, L.Q, You, L.L, Zhang, Y. | | Deposit date: | 2022-09-27 | | Release date: | 2023-04-19 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (3.13 Å) | | Cite: | An SI3-sigma arch stabilizes cyanobacteria transcription initiation complex.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8EIH
 | | Cryo-EM structure of human DNMT3B homo-tetramer (form I) | | Descriptor: | DNA (cytosine-5)-methyltransferase 3B, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION | | Authors: | Lu, J.W, Song, J.K. | | Deposit date: | 2022-09-15 | | Release date: | 2023-09-20 | | Last modified: | 2025-05-21 | | Method: | ELECTRON MICROSCOPY (3.04 Å) | | Cite: | Structural basis for the allosteric regulation and dynamic assembly of DNMT3B.
Nucleic Acids Res., 51, 2023
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8EII
 | | Cryo-EM structure of human DNMT3B homo-tetramer (form II) | | Descriptor: | DNA (cytosine-5)-methyltransferase 3B, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION | | Authors: | Lu, J.W, Song, J.K. | | Deposit date: | 2022-09-15 | | Release date: | 2023-09-20 | | Last modified: | 2025-05-14 | | Method: | ELECTRON MICROSCOPY (3.12 Å) | | Cite: | Structural basis for the allosteric regulation and dynamic assembly of DNMT3B.
Nucleic Acids Res., 51, 2023
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6GFN
 | | METTL16 MTase domain | | Descriptor: | S-ADENOSYL-L-HOMOCYSTEINE, U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase | | Authors: | Chen, K.M, Mendel, M, Homolka, D, McCarthy, A.A, Pillai, R.S. | | Deposit date: | 2018-05-01 | | Release date: | 2018-09-19 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.86 Å) | | Cite: | Methylation of Structured RNA by the m6A Writer METTL16 Is Essential for Mouse Embryonic Development.
Mol. Cell, 71, 2018
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6GFK
 | | delta-N METTL16 MTase domain | | Descriptor: | S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase | | Authors: | Chen, K.M, Mendel, M, Homolka, D, McCarthy, A.A, Pillai, R.S. | | Deposit date: | 2018-04-30 | | Release date: | 2018-09-19 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Methylation of Structured RNA by the m6A Writer METTL16 Is Essential for Mouse Embryonic Development.
Mol. Cell, 71, 2018
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8TCI
 | | Crystal structure of DNMT3C-DNMT3L in complex with CGG DNA | | Descriptor: | (5'-D(P*CP*AP*TP*G)-R(P*(PYO))-D(P*GP*GP*TP*CP*TP*AP*AP*TP*TP*AP*GP*AP*CP*CP*GP*CP*AP*TP*G)-3'), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3C, ... | | Authors: | Khudaverdyan, N, Song, J. | | Deposit date: | 2023-07-01 | | Release date: | 2024-08-14 | | Last modified: | 2024-12-25 | | Method: | X-RAY DIFFRACTION (3.19 Å) | | Cite: | The structure of DNA methyltransferase DNMT3C reveals an activity-tuning mechanism for DNA methylation.
J.Biol.Chem., 300, 2024
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5DPL
 | | The structure of PKMT2 from Rickettsia typhi in complex with AdoHcy | | Descriptor: | S-ADENOSYL-L-HOMOCYSTEINE, protein lysine methyltransferase 2 | | Authors: | Noinaj, N, Abeykoon, A, He, Y, Yang, D.C, Buchanan, S.K. | | Deposit date: | 2015-09-12 | | Release date: | 2016-08-10 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structural Insights into Substrate Recognition and Catalysis in Outer Membrane Protein B (OmpB) by Protein-lysine Methyltransferases from Rickettsia.
J.Biol.Chem., 291, 2016
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5JGK
 | | Crystal structure of GtmA in complex with SAH | | Descriptor: | S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, UbiE/COQ5 family methyltransferase, ... | | Authors: | Dolan, S.K, Bock, T, Hering, V, Jones, G.W, Blankenfeldt, W, Dolye, S. | | Deposit date: | 2016-04-20 | | Release date: | 2017-03-01 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.33 Å) | | Cite: | Structural, mechanistic and functional insight into gliotoxinbis-thiomethylation inAspergillus fumigatus.
Open Biol, 7, 2017
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2GOY
 | | Crystal structure of assimilatory adenosine 5'-phosphosulfate reductase with bound APS | | Descriptor: | ADENOSINE-5'-PHOSPHOSULFATE, IRON/SULFUR CLUSTER, adenosine phosphosulfate reductase | | Authors: | Chartron, J, Carroll, K.S, Shiau, C, Gao, H, Leary, J.A, Bertozzi, C.R, Stout, C.D. | | Deposit date: | 2006-04-14 | | Release date: | 2006-09-19 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Substrate Recognition, Protein Dynamics, and Iron-Sulfur Cluster in Pseudomonas aeruginosa Adenosine 5'-Phosphosulfate Reductase.
J.Mol.Biol., 364, 2006
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3NZM
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9BHG
 | | PRMT1-Tetramer | | Descriptor: | Protein arginine N-methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE | | Authors: | Nadendla, E.K, Wang, C.H. | | Deposit date: | 2024-04-20 | | Release date: | 2025-04-30 | | Method: | ELECTRON MICROSCOPY (3.25 Å) | | Cite: | PRMT1-Tetramer
To Be Published
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