5CIX
| Structure of the complex of type 1 Ribosome inactivating protein with triethanolamine at 1.88 Angstrom resolution | Descriptor: | 2,2',2''-NITRILOTRIETHANOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHATE ION, ... | Authors: | Singh, P.K, Pandey, S, Tyagi, T.K, Singh, A, Kaur, P, Sharma, S, Singh, T.P. | Deposit date: | 2015-07-13 | Release date: | 2015-08-12 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Structure of the complex of type 1 Ribosome inactivating protein with triethanolamine at 1.88 Angstrom resolution. To Be Published
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1YJX
| Crystal structure of human B type phosphoglycerate mutase | Descriptor: | CHLORIDE ION, CITRIC ACID, Phosphoglycerate mutase 1 | Authors: | Wang, Y, Wei, Z, Liu, L, Gong, W. | Deposit date: | 2005-01-16 | Release date: | 2005-05-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of human B-type phosphoglycerate mutase bound with citrate. Biochem.Biophys.Res.Commun., 331, 2005
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8WXV
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3ZM0
| Catalytic domain of human SHP2 | Descriptor: | TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 11 | Authors: | Bohm, K, Schuetz, A, Roske, Y, Heinemann, U. | Deposit date: | 2013-02-04 | Release date: | 2014-04-23 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Selective Inhibitors of the Protein Tyrosine Phosphatase Shp2 Block Cellular Motility and Growth of Cancer Cells in Vitro and in Vivo. Chemmedchem, 10, 2015
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2BJM
| SPE7:Anthrone Complex | Descriptor: | ANTHRONE, IGE SPE7 HEAVY CHAIN, IGE SPE7 LIGHT CHAIN | Authors: | James, L.C, Tawfik, D.S. | Deposit date: | 2005-02-04 | Release date: | 2005-08-18 | Last modified: | 2013-10-30 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structure and Kinetics of a Transient Antibody Binding Intermediate Reveal a Kinetic Discrimination Mechanism in Antigen Recognition Proc.Natl.Acad.Sci.USA, 102, 2005
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4ZM5
| Shigella flexneri lipopolysaccharide O-antigen chain-length regulator WzzBSF - A107P mutant | Descriptor: | CHLORIDE ION, Chain length determinant protein, MAGNESIUM ION | Authors: | Ericsson, D.J, Chang, C.-W, Lonhienne, T, Casey, L, Benning, F, Kobe, B, Tran, E.N.H, Morona, R. | Deposit date: | 2015-05-02 | Release date: | 2016-03-23 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | Structural and Biochemical Analysis of a Single Amino-Acid Mutant of WzzBSF That Alters Lipopolysaccharide O-Antigen Chain Length in Shigella flexneri. Plos One, 10, 2015
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3ZQE
| PrgI-SipD from Salmonella typhimurium in complex with deoxycholate | Descriptor: | (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, GLYCEROL, PROTEIN PRGI, ... | Authors: | Lunelli, M, Kolbe, M. | Deposit date: | 2011-06-09 | Release date: | 2011-08-17 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Crystal Structure of Prgi-Sipd: Insight Into a Secretion Competent State of the Type Three Secretion System Needle Tip and its Interaction with Host Ligands Plos Pathog., 7, 2011
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5FS5
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3ZRC
| pVHL54-213-EloB-EloC complex (4R)-4-HYDROXY-1-[(3-METHYLISOXAZOL-5-YL)ACETYL]-N-[4-(1,3-OXAZOL-5-YL)BENZYL]-L-PROLINAMIDE bound | Descriptor: | (4R)-4-HYDROXY-1-[(3-METHYLISOXAZOL-5-YL)ACETYL]-N-[4-(1,3-OXAZOL-5-YL)BENZYL]-L-PROLINAMIDE, TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 1, TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 2, ... | Authors: | Van Molle, I, Buckley, D.L, Crews, C.M, Ciulli, A. | Deposit date: | 2011-06-15 | Release date: | 2012-03-07 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Targeting the Von Hippel-Lindau E3 Ubiquitin Ligase Using Small Molecules to Disrupt the Vhl/Hif-1Alpha Interaction J.Am.Chem.Soc., 134, 2012
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5FTJ
| Cryo-EM structure of human p97 bound to UPCDC30245 inhibitor | Descriptor: | 1-(3-(5-FLUORO-1H-INDOL-2-YL)PHENYL)PIPERIDIN-4-YL)(2-(4-ISOPROPYL-PIPERAZIN1-YL)ETHYL)-CARBAMATE, ADENOSINE-5'-DIPHOSPHATE, TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE | Authors: | Banerjee, S, Bartesaghi, A, Merk, A, Rao, P, Bulfer, S.L, Yan, Y, Green, N, Mroczkowski, B, Neitz, R.J, Wipf, P, Falconieri, V, Deshaies, R.J, Milne, J.L.S, Huryn, D, Arkin, M, Subramaniam, S. | Deposit date: | 2016-01-14 | Release date: | 2016-01-27 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (2.3 Å) | Cite: | 2.3 A Resolution Cryo-Em Structure of Human P97 and Mechanism of Allosteric Inhibition Science, 351, 2016
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5FV5
| KpFlo11 presents a novel member of the Flo11 family with a unique recognition pattern for homophilic interactions | Descriptor: | ACETATE ION, Flocculation protein FLO11 | Authors: | Kraushaar, T, Brueckner, S, Mikolaiski, M, Schreiner, F, Veelders, M, Moesch, H.U, Essen, L.O. | Deposit date: | 2016-02-03 | Release date: | 2017-02-22 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Kin discrimination in social yeast is mediated by cell surface receptors of the Flo11 adhesin family. Elife, 9, 2020
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4ZFL
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8WXQ
| Structure of WDR5 in complex with WIN motif containing MBD3C | Descriptor: | GLY-ALA-ALA-ARG-CYS-ARG-VAL-PHE-SER-PRO, WD repeat-containing protein 5 | Authors: | Xu, L, Yang, Y. | Deposit date: | 2023-10-30 | Release date: | 2024-06-26 | Last modified: | 2024-07-17 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural studies of WDR5 in complex with MBD3C WIN motif reveal a unique binding mode. J.Biol.Chem., 300, 2024
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3ZIF
| Cryo-EM structures of two intermediates provide insight into adenovirus assembly and disassembly | Descriptor: | HEXON PROTEIN, PENTON PROTEIN, PIX, ... | Authors: | Cheng, L, Huang, X, Li, X, Xiong, W, Sun, W, Yang, C, Zhang, K, Wang, Y, Liu, H, Ji, G, Sun, F, Zheng, C, Zhu, P. | Deposit date: | 2013-01-09 | Release date: | 2014-01-22 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Cryo-Em Structures of Two Bovine Adenovirus Type 3 Intermediates Virology, 450, 2014
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1YKJ
| A45G p-hydroxybenzoate hydroxylase with p-hydroxybenzoate bound | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOIC ACID, P-hydroxybenzoate hydroxylase, ... | Authors: | Cole, L.J, Gatti, D.L, Entsch, B, Ballou, D.P. | Deposit date: | 2005-01-18 | Release date: | 2005-07-26 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Removal of a methyl group causes global changes in p-hydroxybenzoate hydroxylase. Biochemistry, 44, 2005
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8WXX
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2BCZ
| Crystal Structure of a minimal, mutant all-RNA hairpin ribozyme (U39C, G8I, 2'deoxy A-1) | Descriptor: | 5'-R(*CP*GP*GP*UP*GP*AP*IP*AP*AP*GP*GP*G)-3', 5'-R(*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3', 5'-R(*UP*CP*CP*CP*(DA)P*GP*UP*CP*CP*AP*CP*CP*G)-3'), ... | Authors: | Salter, J.D, Wedekind, J.E. | Deposit date: | 2005-10-19 | Release date: | 2006-02-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Water in the Active Site of an All-RNA Hairpin Ribozyme and Effects of Gua8 Base Variants on the Geometry of Phosphoryl Transfer. Biochemistry, 45, 2006
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8VLS
| Structure of VCP in complex with an ATPase activator (D2 domains only, dodecameric form) | Descriptor: | (3R)-N-[2-(ethylsulfanyl)phenyl]-3-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)butanamide, Transitional endoplasmic reticulum ATPase | Authors: | Jones, N.H, Urnivicius, L, Kapoor, T.M. | Deposit date: | 2024-01-12 | Release date: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Allosteric activation of VCP, an AAA unfoldase, by small molecule mimicry. Proc.Natl.Acad.Sci.USA, 121, 2024
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5UDO
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1YE9
| Crystal structure of proteolytically truncated catalase HPII from E. coli | Descriptor: | CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE, catalase HPII | Authors: | Loewen, P.C, Chelikani, P, Carpena, X, Fita, I, Perez-Luque, R, Donald, L.J, Switala, J, Duckworth, H.W. | Deposit date: | 2004-12-28 | Release date: | 2005-04-26 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Characterization of a Large Subunit Catalase Truncated by Proteolytic Cleavage(,) Biochemistry, 44, 2005
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5UE3
| proMMP-9desFnII | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, Matrix metalloproteinase-9, ... | Authors: | Alexander, R.S, Spurlino, J, Milligan, C. | Deposit date: | 2016-12-29 | Release date: | 2017-09-13 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.599 Å) | Cite: | Discovery of a highly selective chemical inhibitor of matrix metalloproteinase-9 (MMP-9) that allosterically inhibits zymogen activation. J. Biol. Chem., 292, 2017
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2BYN
| Crystal structure of apo AChBP from Aplysia californica | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PENTAETHYLENE GLYCOL, SOLUBLE ACETYLCHOLINE RECEPTOR, ... | Authors: | Hansen, S.B, Sulzenbacher, G, Huxford, T, Marchot, P, Taylor, P, Bourne, Y. | Deposit date: | 2005-08-03 | Release date: | 2005-10-05 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Structures of Aplysia Achbp Complexes with Nicotinic Agonists and Antagonists Reveal Distinctive Binding Interfaces and Conformations. Embo J., 24, 2005
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3ZLI
| Crystal structure of JmjC domain of human histone demethylase UTY | Descriptor: | 1,2-ETHANEDIOL, 2-OXOGLUTARIC ACID, FE (II) ION, ... | Authors: | Vollmar, M, Gileadi, C, Shrestha, L, Goubin, S, Johansson, C, Krojer, T, Raynor, J.W, Bradley, A, von Delft, F, Arrowsmith, C.H, Bountra, C, Edwards, A, Oppermann, U. | Deposit date: | 2013-01-31 | Release date: | 2013-02-27 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Human Uty(Kdm6C) is a Male-Specific Nepsilon-Methyl Lysyl Demethylase. J.Biol.Chem., 289, 2014
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5DJQ
| The structure of CBB3 cytochrome oxidase. | Descriptor: | CALCIUM ION, COPPER (II) ION, Cbb3-type cytochrome c oxidase subunit CcoN1, ... | Authors: | Buschmann, S, Warkentin, E, Xie, H, Kohlstaedt, M, Langer, J.D, Ermler, U, Michel, H. | Deposit date: | 2015-09-02 | Release date: | 2016-01-13 | Last modified: | 2016-07-27 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | The structure of cbb3 cytochrome oxidase provides insights into proton pumping. Science, 329, 2010
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3ZN8
| Structural Basis of Signal Sequence Surveillance and Selection by the SRP-SR Complex | Descriptor: | 4.5 S RNA, DIPEPTIDYL AMINOPEPTIDASE B, MAGNESIUM ION, ... | Authors: | von Loeffelholz, O, Knoops, K, Ariosa, A, Zhang, X, Karuppasamy, M, Huard, K, Schoehn, G, Berger, I, Shan, S.O, Schaffitzel, C. | Deposit date: | 2013-02-13 | Release date: | 2013-03-06 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (12 Å) | Cite: | Structural Basis of Signal Sequence Surveillance and Selection by the Srp-Sr Complex Nat.Struct.Mol.Biol., 20, 2013
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