7Z3N
 
 | | Cryo-EM structure of the ribosome-associated RAC complex on the 80S ribosome - RAC-1 conformation | | Descriptor: | 18S rRNA, 26S rRNA, 40S ribosomal protein S0, ... | | Authors: | Kisonaite, M, Wild, K, Sinning, I. | | Deposit date: | 2022-03-02 | | Release date: | 2023-04-12 | | Last modified: | 2023-05-31 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural inventory of cotranslational protein folding by the eukaryotic RAC complex.
Nat.Struct.Mol.Biol., 30, 2023
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7Z3O
 | | Cryo-EM structure of the ribosome-associated RAC complex on the 80S ribosome - RAC-2 conformation | | Descriptor: | 18S rRNA, 26S rRNA, 40S ribosomal protein S0, ... | | Authors: | Kisonaite, M, Wild, K, Sinning, I. | | Deposit date: | 2022-03-02 | | Release date: | 2023-04-12 | | Last modified: | 2023-05-31 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structural inventory of cotranslational protein folding by the eukaryotic RAC complex.
Nat.Struct.Mol.Biol., 30, 2023
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8CF5
 | | Translocation intermediate 1 (TI-1) of 80S S. cerevisiae ribosome with ligands and eEF2 in the presence of sordarin | | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | | Authors: | Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G. | | Deposit date: | 2023-02-02 | | Release date: | 2023-09-20 | | Last modified: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (2.71 Å) | | Cite: | mRNA reading frame maintenance during eukaryotic ribosome translocation.
Nature, 625, 2024
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8CGN
 | | Non-rotated 80S S. cerevisiae ribosome with ligands | | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | | Authors: | Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G. | | Deposit date: | 2023-02-06 | | Release date: | 2023-09-20 | | Last modified: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (2.28 Å) | | Cite: | mRNA reading frame maintenance during eukaryotic ribosome translocation.
Nature, 625, 2024
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8CKU
 | | Translocation intermediate 1 (TI-1*) of 80S S. cerevisiae ribosome with ligands and eEF2 in the absence of sordarin | | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | | Authors: | Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G. | | Deposit date: | 2023-02-16 | | Release date: | 2023-09-20 | | Last modified: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (3.11 Å) | | Cite: | mRNA reading frame maintenance during eukaryotic ribosome translocation.
Nature, 625, 2024
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8BTD
 | | Giardia Ribosome in PRE-T Hybrid State (D1) | | Descriptor: | 5.8S rRNA, 5S rRNA, Large Subunit rRNA, ... | | Authors: | Majumdar, S, Emmerich, A.G, Sanyal, S. | | Deposit date: | 2022-11-28 | | Release date: | 2023-03-22 | | Last modified: | 2023-05-03 | | Method: | ELECTRON MICROSCOPY (4.9 Å) | | Cite: | Insights into translocation mechanism and ribosome evolution from cryo-EM structures of translocation intermediates of Giardia intestinalis.
Nucleic Acids Res., 51, 2023
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8BR8
 | | Giardia ribosome in POST-T state (A1) | | Descriptor: | 40S ribosomal protein S21, 40S ribosomal protein S25, 40S ribosomal protein S26, ... | | Authors: | Majumdar, S, Emmerich, A.G, Sanyal, S. | | Deposit date: | 2022-11-22 | | Release date: | 2023-03-15 | | Last modified: | 2023-05-03 | | Method: | ELECTRON MICROSCOPY (3.35 Å) | | Cite: | Insights into translocation mechanism and ribosome evolution from cryo-EM structures of translocation intermediates of Giardia intestinalis.
Nucleic Acids Res., 51, 2023
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8BRM
 | | Giardia ribosome in POST-T state, no E-site tRNA (A6) | | Descriptor: | 5.8S rRNA, 5S rRNA, Large Subunit rRNA, ... | | Authors: | Majumdar, S, Emmerich, A.G, Sanyal, S. | | Deposit date: | 2022-11-23 | | Release date: | 2023-03-15 | | Last modified: | 2023-05-03 | | Method: | ELECTRON MICROSCOPY (3.33 Å) | | Cite: | Insights into translocation mechanism and ribosome evolution from cryo-EM structures of translocation intermediates of Giardia intestinalis.
Nucleic Acids Res., 51, 2023
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8BSI
 | | Giardia ribosome chimeric hybrid-like GDP+Pi bound state (B1) | | Descriptor: | 40S ribosomal protein S21, 40S ribosomal protein S25, 40S ribosomal protein S26, ... | | Authors: | Majumdar, S, Emmerich, A.G, Sanyal, S. | | Deposit date: | 2022-11-25 | | Release date: | 2023-03-15 | | Last modified: | 2023-05-03 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Insights into translocation mechanism and ribosome evolution from cryo-EM structures of translocation intermediates of Giardia intestinalis.
Nucleic Acids Res., 51, 2023
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8CIV
 | | Translocation intermediate 5 (TI-5) of 80S S. cerevisiae ribosome with ligands and eEF2 in the presence of sordarin | | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | | Authors: | Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G. | | Deposit date: | 2023-02-10 | | Release date: | 2023-09-20 | | Last modified: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (2.47 Å) | | Cite: | mRNA reading frame maintenance during eukaryotic ribosome translocation.
Nature, 625, 2024
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8CMJ
 | | Translocation intermediate 4 (TI-4*) of 80S S. cerevisiae ribosome with eEF2 in the absence of sordarin | | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | | Authors: | Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G. | | Deposit date: | 2023-02-20 | | Release date: | 2023-09-20 | | Last modified: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (3.79 Å) | | Cite: | mRNA reading frame maintenance during eukaryotic ribosome translocation.
Nature, 625, 2024
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8CG8
 | | Translocation intermediate 3 (TI-3) of 80S S. cerevisiae ribosome with ligands and eEF2 in the presence of sordarin | | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | | Authors: | Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G. | | Deposit date: | 2023-02-03 | | Release date: | 2023-09-20 | | Last modified: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (2.57 Å) | | Cite: | mRNA reading frame maintenance during eukaryotic ribosome translocation.
Nature, 625, 2024
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8CEH
 | | Translocation intermediate 4 (TI-4) of 80S S. cerevisiae ribosome with ligands and eEF2 in the presence of sordarin | | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | | Authors: | Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G. | | Deposit date: | 2023-02-01 | | Release date: | 2023-09-20 | | Last modified: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (2.05 Å) | | Cite: | mRNA reading frame maintenance during eukaryotic ribosome translocation.
Nature, 625, 2024
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5APO
 | | Structure of the yeast 60S ribosomal subunit in complex with Arx1, Alb1 and C-terminally tagged Rei1 | | Descriptor: | 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | | Authors: | Greber, B.J, Gerhardy, S, Leitner, A, Leibundgut, M, Salem, M, Boehringer, D, Leulliot, N, Aebersold, R, Panse, V.G, Ban, N. | | Deposit date: | 2015-09-17 | | Release date: | 2015-12-16 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (3.41 Å) | | Cite: | Insertion of the Biogenesis Factor Rei1 Probes the Ribosomal Tunnel during 60S Maturation.
Cell(Cambridge,Mass.), 164, 2016
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8B2L
 | | Cryo-EM structure of the plant 80S ribosome | | Descriptor: | 18S rRNA, 25S rRNA, 30S ribosomal protein S15, ... | | Authors: | Smirnova, J, Loerke, J, Kleinau, G, Schmidt, A, Buerger, J, Meyer, E.H, Mielke, T, Scheerer, P, Bock, R, Spahn, C.M.T, Zoschke, R. | | Deposit date: | 2022-09-14 | | Release date: | 2023-08-23 | | Last modified: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (2.2 Å) | | Cite: | Structure of the actively translating plant 80S ribosome at 2.2 angstrom resolution.
Nat.Plants, 9, 2023
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8BSJ
 | | Giardia Ribosome in PRE-T Classical State (C) | | Descriptor: | 40S ribosomal protein S21, 40S ribosomal protein S25, 40S ribosomal protein S26, ... | | Authors: | Majumdar, S, Emmerich, A.G, Sanyal, S. | | Deposit date: | 2022-11-25 | | Release date: | 2023-03-22 | | Last modified: | 2023-05-03 | | Method: | ELECTRON MICROSCOPY (6.49 Å) | | Cite: | Insights into translocation mechanism and ribosome evolution from cryo-EM structures of translocation intermediates of Giardia intestinalis.
Nucleic Acids Res., 51, 2023
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1U0G
 | | Crystal structure of mouse phosphoglucose isomerase in complex with erythrose 4-phosphate | | Descriptor: | BETA-MERCAPTOETHANOL, ERYTHOSE-4-PHOSPHATE, GLYCEROL, ... | | Authors: | Solomons, J.T.G, Zimmerly, E.M, Burns, S, Krishnamurthy, N, Swan, M.K, Krings, S, Muirhead, H, Chirgwin, J, Davies, C. | | Deposit date: | 2004-07-13 | | Release date: | 2004-11-02 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | The crystal structure of mouse phosphoglucose isomerase at 1.6A resolution and its complex with glucose 6-phosphate reveals the catalytic mechanism of sugar ring opening.
J.Mol.Biol., 342, 2004
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6HD7
 | | Cryo-EM structure of the ribosome-NatA complex | | Descriptor: | 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, 5.8S rRNA, 5S rRNA, ... | | Authors: | Knorr, A.G, Becker, T, Beckmann, R. | | Deposit date: | 2018-08-17 | | Release date: | 2018-12-19 | | Last modified: | 2019-01-16 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Ribosome-NatA architecture reveals that rRNA expansion segments coordinate N-terminal acetylation.
Nat. Struct. Mol. Biol., 26, 2019
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8RXH
 | | CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME WITH A/P/E-site tRNA AND mRNA : PARENTAL STRAIN | | Descriptor: | (2S)-2-[2-[4-[[(2R,3S,4S)-3-acetyloxy-4-oxidanyl-pyrrolidin-2-yl]methyl]phenoxy]ethanoylamino]-6-azanyl-hexanoic acid, 40S ribosomal protein S12, 40S ribosomal protein S14, ... | | Authors: | Rajan, K.S, Yonath, A. | | Deposit date: | 2024-02-07 | | Release date: | 2024-05-15 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (2.93 Å) | | Cite: | Structural and mechanistic insights into the function of Leishmania ribosome lacking a single pseudouridine modification.
Cell Rep, 43, 2024
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8RXX
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7CZB
 | | The cryo-EM structure of the ERAD retrotranslocation channel formed by human Derlin-1 | | Descriptor: | Derlin-1 | | Authors: | Rao, B, Li, S, Yao, D, Wang, Q, Xia, Y, Jia, Y, Shen, Y, Cao, Y. | | Deposit date: | 2020-09-07 | | Release date: | 2021-03-17 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | The cryo-EM structure of an ERAD protein channel formed by tetrameric human Derlin-1.
Sci Adv, 7, 2021
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2DJQ
 | | The solution structure of the first SH3 domain of mouse SH3 domain containing ring finger 2 | | Descriptor: | SH3 domain containing ring finger 2 | | Authors: | Sasagawa, A, Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2006-04-05 | | Release date: | 2006-10-05 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | The solution structure of the first SH3 domain of mouse SH3 domain containing ring finger 2
To be Published
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2WDT
 | | Crystal structure of Plasmodium falciparum UCHL3 in complex with the suicide inhibitor UbVME | | Descriptor: | CHLORIDE ION, UBIQUITIN, UBIQUITIN CARBOXYL-TERMINAL HYDROLASE L3 | | Authors: | Weihofen, W.A, Artavanis-Tsakonas, K, Gaudet, R, Ploegh, H.L. | | Deposit date: | 2009-03-26 | | Release date: | 2009-12-29 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Characterization and Structural Studies of the Plasmodium Falciparum Ubiquitin and Nedd8 Hydrolase Uchl3.
J.Biol.Chem., 285, 2010
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2WE6
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