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8J8N
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Structure of p53 DNA-binding domain and ZNF568 KRAB domain complex
Descriptor: Cellular tumor antigen p53, ZINC ION, Zinc finger protein 568
Authors:Han, C.W.
Deposit date:2023-05-02
Release date:2024-05-15
Method:ELECTRON MICROSCOPY (9.02 Å)
Cite:Structure of p53 DNA-binding domain and ZNF568 KRAB domain complex
To Be Published
3RU4
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Crystal structure of the Bowman-Birk serine protease inhibitor BTCI in complex with trypsin and chymotrypsin
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, 1,2-ETHANEDIOL, Bowman-Birk type seed trypsin and chymotrypsin inhibitor, ...
Authors:Esteves, G.F, Santos, C.R, Ventura, M.M, Barbosa, J.A.R.G, Freitas, S.M.
Deposit date:2011-05-04
Release date:2012-08-29
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Crystal structure of the Bowman-Birk serine protease inhibitor BTCI in complex with trypsin and chymotrypsin
To be Published
1VGC
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GAMMA-CHYMOTRYPSIN L-PARA-CHLORO-1-ACETAMIDO BORONIC ACID INHIBITOR COMPLEX
Descriptor: GAMMA CHYMOTRYPSIN, L-1-(4-CHLOROPHENYL)-2-(ACETAMIDO)ETHANE BORONIC ACID, SULFATE ION
Authors:Stoll, V.S, Eger, B.T, Hynes, R.C, Martichonok, V, Jones, J.B, Pai, E.F.
Deposit date:1997-05-01
Release date:1997-11-12
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Differences in binding modes of enantiomers of 1-acetamido boronic acid based protease inhibitors: crystal structures of gamma-chymotrypsin and subtilisin Carlsberg complexes.
Biochemistry, 37, 1998
3T62
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Crystal structure of recombinant Kunitz Type serine protease Inhibitor-1 from the Caribbean Sea anemone Stichodactyla helianthus in complex with bovine chymotrypsin
Descriptor: Chymotrypsinogen A, Kunitz-type proteinase inhibitor SHPI-1, SULFATE ION
Authors:Garcia-Fernandez, R, Dominguez, R, Oberthuer, D, Pons, T, Gonzalez-Gonzalez, Y, Chavez, M.A, Betzel, C, Redecke, L.
Deposit date:2011-07-28
Release date:2012-08-01
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural insights into chymotrypsin inhibition by the Kunitz-type inhibitor-1 from the marine invertebrate Stichodactyla helianthus
To be Published
8E7B
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Crystal structure of the p53 (Y107H) core domain monoclinic P form
Descriptor: Cellular tumor antigen p53, ZINC ION
Authors:Lovell, S, Liu, L, Battaile, K.P, Miller, S, Karanicolas, J.
Deposit date:2022-08-23
Release date:2023-05-17
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:An African-Specific Variant of TP53 Reveals PADI4 as a Regulator of p53-Mediated Tumor Suppression.
Cancer Discov, 13, 2023
8E7A
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Crystal structure of the p53 (Y107H) core domain orthorhombic P form
Descriptor: Cellular tumor antigen p53, ZINC ION
Authors:Lovell, S, Liu, L, Battaile, K.P, Miller, S, Karanicolas, J.
Deposit date:2022-08-23
Release date:2023-05-17
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:An African-Specific Variant of TP53 Reveals PADI4 as a Regulator of p53-Mediated Tumor Suppression.
Cancer Discov, 13, 2023
8F2I
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P53 monomer structure
Descriptor: Cellular tumor antigen p53
Authors:Solares, M, Kelly, D.F.
Deposit date:2022-11-08
Release date:2022-11-23
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (5 Å)
Cite:High-Resolution Imaging of Human Cancer Proteins Using Microprocessor Materials.
Chembiochem, 23, 2022
8F2H
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Wild type P53 dimer structure from human cancer cells
Descriptor: Cellular tumor antigen p53
Authors:Solares, M, Kelly, D.F.
Deposit date:2022-11-08
Release date:2022-11-23
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:High-Resolution Imaging of Human Cancer Proteins Using Microprocessor Materials.
Chembiochem, 23, 2022
1L5J
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BU of 1l5j by Molmil
CRYSTAL STRUCTURE OF E. COLI ACONITASE B.
Descriptor: ACONITATE ION, Aconitate hydratase 2, FE3-S4 CLUSTER
Authors:Williams, C.H, Stillman, T.J, Barynin, V.V, Sedelnikova, S.E, Tang, Y, Green, J, Guest, J.R, Artymiuk, P.J.
Deposit date:2002-03-07
Release date:2002-06-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:E. coli aconitase B structure reveals a HEAT-like domain with implications for protein-protein recognition.
Nat.Struct.Biol., 9, 2002
1T8O
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CRYSTAL STRUCTURE OF THE P1 TRP BPTI MUTANT- BOVINE CHYMOTRYPSIN COMPLEX
Descriptor: Chymotrypsin A, Pancreatic trypsin inhibitor, SULFATE ION
Authors:Czapinska, H, Helland, R, Otlewski, J, Smalas, A.O.
Deposit date:2004-05-13
Release date:2005-03-08
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures of five bovine chymotrypsin complexes with P1 BPTI variants.
J.Mol.Biol., 344, 2004
2VGC
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BU of 2vgc by Molmil
GAMMA-CHYMOTRYPSIN D-PARA-CHLORO-1-ACETAMIDO BORONIC ACID INHIBITOR COMPLEX
Descriptor: D-1-(4-CHLOROPHENYL)-2-(ACETAMIDO)ETHANE BORONIC ACID, GAMMA CHYMOTRYPSIN, SULFATE ION
Authors:Stoll, V.S, Eger, B.T, Hynes, R.C, Martichonok, V, Jones, J.B, Pai, E.F.
Deposit date:1997-05-01
Release date:1997-11-12
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Differences in binding modes of enantiomers of 1-acetamido boronic acid based protease inhibitors: crystal structures of gamma-chymotrypsin and subtilisin Carlsberg complexes.
Biochemistry, 37, 1998
3TS8
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Crystal structure of a multidomain human p53 tetramer bound to the natural CDKN1A(p21) p53-response element
Descriptor: CDKN1A(p21) anti-sense strand, CDKN1A(p21) sense strand, Cellular tumor antigen p53, ...
Authors:Halazonetis, T.D, Emamzadah, S.
Deposit date:2011-09-12
Release date:2011-11-23
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of a Multidomain Human p53 Tetramer Bound to the Natural CDKN1A (p21) p53-Response Element.
Mol Cancer Res, 9, 2011
1MTN
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BOVINE ALPHA-CHYMOTRYPSIN:BPTI CRYSTALLIZATION
Descriptor: ALPHA-CHYMOTRYPSIN, BASIC PANCREATIC TRYPSIN INHIBITOR, SULFATE ION
Authors:Capasso, C, Rizzi, M, Menegatti, E, Ascenzi, P, Bolognesi, M.
Deposit date:1996-03-28
Release date:1996-08-17
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the bovine alpha-chymotrypsin:Kunitz inhibitor complex. An example of multiple protein:protein recognition sites.
J.Mol.Recog., 10, 1997
1T8M
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BU of 1t8m by Molmil
CRYSTAL STRUCTURE OF THE P1 HIS BPTI MUTANT- BOVINE CHYMOTRYPSIN COMPLEX
Descriptor: Chymotrypsin A, Pancreatic trypsin inhibitor, SULFATE ION
Authors:Czapinska, H, Helland, R, Otlewski, J, Smalas, A.O.
Deposit date:2004-05-13
Release date:2005-03-08
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structures of five bovine chymotrypsin complexes with P1 BPTI variants.
J.Mol.Biol., 344, 2004
2XWR
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BU of 2xwr by Molmil
Crystal structure of the DNA-binding domain of human p53 with extended N terminus
Descriptor: CELLULAR TUMOR ANTIGEN P53, ZINC ION
Authors:Joerger, A.C, Natan, E, Fersht, A.R.
Deposit date:2010-11-04
Release date:2011-03-30
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Interaction of the P53 DNA-Binding Domain with its N-Terminal Extension Modulates the Stability of the P53 Tetramer.
J.Mol.Biol., 409, 2011
2YBG
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BU of 2ybg by Molmil
Structure of Lys120-acetylated p53 core domain
Descriptor: CELLULAR TUMOR ANTIGEN P53, ZINC ION
Authors:Arbely, E, Allen, M.D, Joerger, A.C, Fersht, A.R.
Deposit date:2011-03-08
Release date:2011-05-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Acetylation of Lysine 120 of P53 Endows DNA- Binding Specificity at Effective Physiological Salt Concentration.
Proc.Natl.Acad.Sci.USA, 108, 2011
1T8L
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BU of 1t8l by Molmil
CRYSTAL STRUCTURE OF THE P1 MET BPTI MUTANT- BOVINE CHYMOTRYPSIN COMPLEX
Descriptor: Chymotrypsin A, Pancreatic trypsin inhibitor, SULFATE ION
Authors:Czapinska, H, Helland, R, Otlewski, J, Smalas, A.O.
Deposit date:2004-05-13
Release date:2005-03-08
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structures of five bovine chymotrypsin complexes with P1 BPTI variants.
J.Mol.Biol., 344, 2004
1T8N
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BU of 1t8n by Molmil
CRYSTAL STRUCTURE OF THE P1 THR BPTI MUTANT- BOVINE CHYMOTRYPSIN COMPLEX
Descriptor: Chymotrypsin A, Pancreatic trypsin inhibitor, SULFATE ION
Authors:Czapinska, H, Helland, R, Otlewski, J, Smalas, A.O.
Deposit date:2004-05-13
Release date:2005-03-08
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structures of five bovine chymotrypsin complexes with P1 BPTI variants.
J.Mol.Biol., 344, 2004
1NJE
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BU of 1nje by Molmil
THYMIDYLATE SYNTHASE WITH 2'-DEOXYCYTIDINE 5'-MONOPHOSPHATE (DCMP)
Descriptor: 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE
Authors:Finer-Moore, J, Stroud, R.M.
Deposit date:1996-01-23
Release date:1996-07-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Partitioning roles of side chains in affinity, orientation, and catalysis with structures for mutant complexes: asparagine-229 in thymidylate synthase.
Biochemistry, 35, 1996
1N8O
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Crystal structure of a complex between bovine chymotrypsin and ecotin
Descriptor: Chymotrypsin A, A chain, C chain, ...
Authors:Cambillau, C, Spinelli, S, Lauwereys, M.
Deposit date:2002-11-21
Release date:2002-12-18
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of a Complex Between Bovine Chymotrypsin and Ecotin at 2.0 A Resolution
To be Published
1NGQ
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BU of 1ngq by Molmil
N1G9 (IGG1-LAMBDA) FAB FRAGMENT
Descriptor: N1G9 (IGG1-LAMBDA), SULFATE ION
Authors:Mizutani, R, Satow, Y.
Deposit date:1995-06-23
Release date:1996-07-11
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Three-dimensional structures of the Fab fragment of murine N1G9 antibody from the primary immune response and of its complex with (4-hydroxy-3-nitrophenyl)acetate.
J.Mol.Biol., 254, 1995
2JET
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BU of 2jet by Molmil
Crystal structure of a trypsin-like mutant (S189D , A226G) chymotrypsin.
Descriptor: CHYMOTRYPSINOGEN B CHAIN A, CHYMOTRYPSINOGEN B CHAIN B, CHYMOTRYPSINOGEN B CHAIN C
Authors:Jelinek, B, Katona, G, Fodor, K, Venekei, I, Graf, L.
Deposit date:2007-01-22
Release date:2007-09-18
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Crystal Structure of a Trypsin-Like Mutant Chymotrypsin: The Role of Position 226 in the Activity and Specificity of S189D Chymotrypsin.
Protein J., 27, 2008
2IOO
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BU of 2ioo by Molmil
Crystal structure of the mouse p53 core domain
Descriptor: Cellular tumor antigen p53, ZINC ION
Authors:Ho, W.C, Luo, C, Zhao, K, Chai, X, Fitzgerald, M.X, Marmorstein, R.
Deposit date:2006-10-10
Release date:2006-12-05
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:High-resolution structure of the p53 core domain: implications for binding small-molecule stabilizing compounds.
Acta Crystallogr.,Sect.D, 62, 2006
2GMT
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THREE-DIMENSIONAL STRUCTURE OF CHYMOTRYPSIN INACTIVATED WITH (2S) N-ACETYL-L-ALANYL-L-PHENYLALANYL-CHLOROETHYL KETONE: IMPLICATIONS FOR THE MECHANISM OF INACTIVATION OF SERINE PROTEASES BY CHLOROKETONES
Descriptor: (2S) N-ACETYL-L-ALANYL-ALPHAL-PHENYLALANYL-CHLOROETHYLKETONE, GAMMA-CHYMOTRYPSIN
Authors:Kreutter, K, Steinmetz, A.C.U, Liang, T.-C, Prorok, M, Abeles, R, Ringe, D.
Deposit date:1994-09-07
Release date:1994-11-01
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Three-dimensional structure of chymotrypsin inactivated with (2S)-N-acetyl-L-alanyl-L-phenylalanyl alpha-chloroethane: implications for the mechanism of inactivation of serine proteases by chloroketones.
Biochemistry, 33, 1994
2IOI
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Crystal structure of the mouse p53 core domain at 1.55 A
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Cellular tumor antigen p53, ZINC ION
Authors:Ho, W.C, Luo, C, Zhao, K, Chai, X, Fitzgerald, M.X, Marmorstein, R.
Deposit date:2006-10-10
Release date:2006-12-05
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:High-resolution structure of the p53 core domain: implications for binding small-molecule stabilizing compounds.
Acta Crystallogr.,Sect.D, 62, 2006

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数据于2024-10-16公开中

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