1HWP
 
 | | EBULIN COMPLEXED WITH PTEROIC ACID, TRIGONAL CRYSTAL FORM | | Descriptor: | EBULIN, PTEROIC ACID, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, ... | | Authors: | Pascal, J.M, Day, P.J, Monzingo, A.F, Ernst, S.R, Robertus, J.D. | | Deposit date: | 2001-01-09 | | Release date: | 2001-01-24 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | 2.8-A crystal structure of a nontoxic type-II ribosome-inactivating protein, ebulin l.
Proteins, 43, 2001
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1HWM
 | | EBULIN,ORTHORHOMBIC CRYSTAL FORM MODEL | | Descriptor: | EBULIN, alpha-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-galactopyranose | | Authors: | Pascal, J.M, Day, P.J, Monzingo, A.F, Ernst, S.R, Robertus, J.D. | | Deposit date: | 2001-01-09 | | Release date: | 2001-01-24 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | 2.8-A crystal structure of a nontoxic type-II ribosome-inactivating protein, ebulin l.
Proteins, 43, 2001
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1HWN
 | | EBULIN COMPLEXED WITH GALACTOSE, TRIGONAL CRYSTAL FORM | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, EBULIN, beta-D-galactopyranose | | Authors: | Pascal, J.M, Day, P.J, Monzingo, A.F, Ernst, S.R, Robertus, J.D. | | Deposit date: | 2001-01-09 | | Release date: | 2001-01-24 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | 2.8-A crystal structure of a nontoxic type-II ribosome-inactivating protein, ebulin l.
Proteins, 43, 2001
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1HWO
 | | EBULIN COMPLEXED WITH LACTOSE, TRIGONAL CRYSTAL FORM | | Descriptor: | EBULIN, beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | Authors: | Pascal, J.M, Day, P.J, Monzingo, A.F, Ernst, S.R, Robertus, J.D. | | Deposit date: | 2001-01-09 | | Release date: | 2001-01-24 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | 2.8-A crystal structure of a nontoxic type-II ribosome-inactivating protein, ebulin l.
Proteins, 43, 2001
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4M1U
 | | The crystal structure of Stx2 and a disaccharide ligand | | Descriptor: | 2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-4)-methyl beta-D-galactopyranoside, 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, Shiga toxin 2 A-subunit, ... | | Authors: | Yin, J, James, M.N.G, Jacobson, J.M, Kitov, P.I, Bundle, D.R, Mulvey, G, Armstrong, G. | | Deposit date: | 2013-08-04 | | Release date: | 2013-11-20 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.56 Å) | | Cite: | The crystal structure of shiga toxin type 2 with bound disaccharide guides the design of a heterobifunctional toxin inhibitor.
J.Biol.Chem., 289, 2014
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7KD2
 | | Ricin bound to VHH antibody V11B2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Ricin chain A, ... | | Authors: | Rudolph, M.J. | | Deposit date: | 2020-10-07 | | Release date: | 2021-08-04 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Structural Analysis of Toxin-Neutralizing, Single-Domain Antibodies that Bridge Ricin's A-B Subunit Interface.
J.Mol.Biol., 433, 2021
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7KDU
 | | Ricin bound to VHH antibody V5E4 | | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ricin chain A, ... | | Authors: | Rudolph, M.J. | | Deposit date: | 2020-10-09 | | Release date: | 2021-08-04 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.809 Å) | | Cite: | Structural Analysis of Toxin-Neutralizing, Single-Domain Antibodies that Bridge Ricin's A-B Subunit Interface.
J.Mol.Biol., 433, 2021
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7KBK
 | | Ricin bound to VHH antibody V6E11 | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Ricin, ... | | Authors: | Rudolph, M.J. | | Deposit date: | 2020-10-02 | | Release date: | 2021-08-04 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.091 Å) | | Cite: | Structural Analysis of Toxin-Neutralizing, Single-Domain Antibodies that Bridge Ricin's A-B Subunit Interface.
J.Mol.Biol., 433, 2021
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7KBI
 | | Ricin bound to VHH antibody V5E1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Ricin chain A, ... | | Authors: | Rudolph, M.J. | | Deposit date: | 2020-10-02 | | Release date: | 2021-08-04 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (3.049 Å) | | Cite: | Structural Analysis of Toxin-Neutralizing, Single-Domain Antibodies that Bridge Ricin's A-B Subunit Interface.
J.Mol.Biol., 433, 2021
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7KD0
 | | Ricin bound to VHH antibody V2C11 | | Descriptor: | 1,2-ETHANEDIOL, Anti-RON nanobody, CHLORIDE ION, ... | | Authors: | Rudolph, M.J. | | Deposit date: | 2020-10-07 | | Release date: | 2021-08-04 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.768 Å) | | Cite: | Structural Analysis of Toxin-Neutralizing, Single-Domain Antibodies that Bridge Ricin's A-B Subunit Interface.
J.Mol.Biol., 433, 2021
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7KDM
 | | Ricin bound to VHH antibody V5G6 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-RON nanobody, CHLORIDE ION, ... | | Authors: | Rudolph, M.J. | | Deposit date: | 2020-10-08 | | Release date: | 2021-08-04 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.301 Å) | | Cite: | Structural Analysis of Toxin-Neutralizing, Single-Domain Antibodies that Bridge Ricin's A-B Subunit Interface.
J.Mol.Biol., 433, 2021
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7KC9
 | | Ricin bound to VHH antibody V5G1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Ricin chain A, ... | | Authors: | Rudolph, M.J. | | Deposit date: | 2020-10-05 | | Release date: | 2021-08-04 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.301 Å) | | Cite: | Structural Analysis of Toxin-Neutralizing, Single-Domain Antibodies that Bridge Ricin's A-B Subunit Interface.
J.Mol.Biol., 433, 2021
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4P2C
 | | Complex of Shiga toxin 2e with a neutralizing single-domain antibody | | Descriptor: | Nanobody 1, Anti-F4+ETEC bacteria VHH variable region, Shiga toxin 2e, ... | | Authors: | Lo, A.W.H, Moonens, K, De Kerpel, M, Brys, L, Pardon, E, Remaut, H, De Greve, H. | | Deposit date: | 2014-03-03 | | Release date: | 2014-07-30 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.818 Å) | | Cite: | The Molecular Mechanism of Shiga Toxin Stx2e Neutralization by a Single-domain Antibody Targeting the Cell Receptor-binding Domain.
J.Biol.Chem., 289, 2014
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4EB2
 | | Crystal structure Mistletoe Lectin I from Viscum album in complex with n-acetyl-d-glucosamine at 1.94 A resolution. | | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Laskov, A.A, Prokofev, I.I, Gabdoulkhakov, A.G, Betzel, C, Mikhailov, A.M. | | Deposit date: | 2012-03-23 | | Release date: | 2013-03-27 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.94 Å) | | Cite: | Crystal structure Mistletoe Lectin I from Viscum album in complex with N-acetyl-D-glucosamine at 1.94 A resolution.
To be Published
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2Q3N
 | | Agglutinin from Abrus Precatorius (APA-I) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Agglutinin-1 A chain, Agglutinin-1 B chain | | Authors: | Bagaria, A, Surendranath, K, Ramagopal, U.A, Ramakumar, S, Karande, A.A. | | Deposit date: | 2007-05-30 | | Release date: | 2007-06-26 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Structure-Function Analysis and Insights into the Reduced Toxicity of Abrus precatorius Agglutinin I in Relation to Abrin.
J.Biol.Chem., 281, 2006
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2R9K
 | | Crystal Structure of Misteltoe Lectin I in Complex with Phloretamide | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(4-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(4-hydroxyphenyl)propanamide, ... | | Authors: | Meyer, A, Rypniewski, W, Celewicz, L, Erdmann, V.A, Voelter, W, Betzel, C. | | Deposit date: | 2007-09-13 | | Release date: | 2007-10-30 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | The mistletoe lectin I--phloretamide structure reveals a new function of plant lectins.
Biochem.Biophys.Res.Commun., 364, 2007
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2RG9
 | | Crystal structure of viscum album mistletoe lectin I in native state at 1.95 A resolution, comparison of structure active site conformation in ricin and in viscumin | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, AZIDE ION, Beta-galactoside-specific lectin 1 chain A isoform 1, ... | | Authors: | Karpechenko, N.U, Timofeev, V.I, Gabdoulkhakov, A.G, Mikhailov, A.M. | | Deposit date: | 2007-10-03 | | Release date: | 2008-10-07 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Crystal structure of viscum album mistletoe lectin I in native state at 1.95 A resolution, comparison of structure active site conformation in ricin and in viscumin
To be Published
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2VLC
 | | Crystal structure of Natural Cinnamomin (Isoform III) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ribosome-inactivating protein, beta-D-mannopyranose, ... | | Authors: | Azzi, A, Wang, T, Zhu, D.-W, Zou, Y.-S, Liu, W.-Y, Lin, S.-X. | | Deposit date: | 2008-01-11 | | Release date: | 2009-02-10 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.95 Å) | | Cite: | Crystal Structure of Native Cinnamomin Isoform III and its Comparison with Other Ribosome Inactivating Proteins.
Proteins: Struct., Funct., Bioinf., 74, 2009
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7U6V
 | | Cryo-EM structure of Shiga toxin 2 in complex with the native ribosomal P-stalk | | Descriptor: | C-terminal domain (CTD) from the Ribosomal P-stalk, Shiga toxin 2a subunit A (Stx2A), Shiga toxin 2a subunit B (Stx2B) | | Authors: | Kulczyk, A.W. | | Deposit date: | 2022-03-06 | | Release date: | 2023-01-11 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Cryo-EM structure of Shiga toxin 2 in complex with the native ribosomal P-stalk reveals residues involved in the binding interaction.
J.Biol.Chem., 299, 2022
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3O5W
 | | Binding of kinetin in the active site of mistletoe lectin I | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Malecki, P.H, Meyer, A, Rypniewski, W, Szymanski, M, Barciszewski, J, Betzel, C. | | Deposit date: | 2010-07-28 | | Release date: | 2011-09-14 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Binding of the plant hormone kinetin in the active site of Mistletoe Lectin I from Viscum album.
Biochim.Biophys.Acta, 1824, 2012
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7UJJ
 | | Stx2a and DARPin complex | | Descriptor: | 1,2-ETHANEDIOL, 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, DARPin, ... | | Authors: | Jiang, M, Zhang, J. | | Deposit date: | 2022-03-30 | | Release date: | 2023-04-12 | | Method: | ELECTRON MICROSCOPY (6.5 Å) | | Cite: | A Multi-Specific DARPin Potently Neutralizes Shiga Toxin 2 via Simultaneous Modulation of Both Toxin Subunits.
Bioengineering (Basel), 9, 2022
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7VHF
 | | Crystal structure of the STX2a complexed with RRA peptide | | Descriptor: | 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, GLYCEROL, RRA peptide, ... | | Authors: | Senda, M, Takahashi, M, Nishikawa, K, Senda, T. | | Deposit date: | 2021-09-22 | | Release date: | 2022-07-20 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | A unique peptide-based pharmacophore identifies an inhibitory compound against the A-subunit of Shiga toxin.
Sci Rep, 12, 2022
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7VHE
 | | Crystal structure of the STX2a complexed with RRRA peptide | | Descriptor: | 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, GLYCEROL, RRRA peptide, ... | | Authors: | Senda, M, Takahashi, M, Nishikawa, K, Senda, T. | | Deposit date: | 2021-09-22 | | Release date: | 2022-07-20 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | A unique peptide-based pharmacophore identifies an inhibitory compound against the A-subunit of Shiga toxin.
Sci Rep, 12, 2022
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7VHC
 | | Crystal structure of the STX2a complexed with AR4A peptide | | Descriptor: | 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, Shiga toxin 2 B subunit, inhibitor peptide, ... | | Authors: | Senda, M, Takahashi, M, Nishikawa, K, Senda, T. | | Deposit date: | 2021-09-22 | | Release date: | 2022-07-20 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | A unique peptide-based pharmacophore identifies an inhibitory compound against the A-subunit of Shiga toxin.
Sci Rep, 12, 2022
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7VHD
 | | Crystal structure of the STX2a complexed with R4A peptide | | Descriptor: | 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, ARG-ARG-ARG-ARG-ALA, Shiga toxin 2 B subunit, ... | | Authors: | Senda, M, Takahashi, M, Nishikawa, K, Senda, T. | | Deposit date: | 2021-09-22 | | Release date: | 2022-07-20 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | A unique peptide-based pharmacophore identifies an inhibitory compound against the A-subunit of Shiga toxin.
Sci Rep, 12, 2022
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