7VHC

Crystal structure of the STX2a complexed with AR4A peptide

Summary for 7VHC

• Entry DOI: 10.2210/pdb7vhc/pdb
• Descriptor: rRNA N-glycosylase, Shiga toxin 2 B subunit, inhibitor peptide, ALA-ARG-ARG-ARG-ARG-ALA, ... (5 entities in total)
• Functional Keywords: shiga toxin, toxin
• Biological source: Escherichia coli; More
• Total number of polymer chains: 7
• Total formula weight: 73943.09

Authors

Senda, M.,Takahashi, M.,Nishikawa, K.,Senda, T. (deposition date: 2021-09-22, release date: 2022-07-20, Last modification date: 2023-11-29)

• Primary citation: Watanabe-Takahashi, M.,Senda, M.,Yoshino, R.,Hibino, M.,Hama, S.,Terada, T.,Shimizu, K.,Senda, T.,Nishikawa, K.; A unique peptide-based pharmacophore identifies an inhibitory compound against the A-subunit of Shiga toxin.; Sci Rep, 12:11443-11443, 2022; PubMed: 35794188; DOI: 10.1038/s41598-022-15316-1

Experimental method

X-RAY DIFFRACTION (1.8 Å)