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5WF0
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BU of 5wf0 by Molmil
70S ribosome-EF-Tu H84A complex with GTP and near-cognate tRNA (Complex C2)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Fislage, M, Frank, J.
Deposit date:2017-07-11
Release date:2018-05-02
Last modified:2019-11-20
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A.
Nucleic Acids Res., 46, 2018
5WE6
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BU of 5we6 by Molmil
70S ribosome-EF-Tu H84A complex with GTP and cognate tRNA
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Fislage, M, Frank, J.
Deposit date:2017-07-07
Release date:2018-04-25
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A.
Nucleic Acids Res., 46, 2018
5WE4
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BU of 5we4 by Molmil
70S ribosome-EF-Tu wt complex with GppNHp
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Fislage, M, Brown, Z, Frank, J.
Deposit date:2017-07-07
Release date:2018-04-25
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A.
Nucleic Acids Res., 46, 2018
5WDT
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BU of 5wdt by Molmil
70S ribosome-EF-Tu H84A complex with GppNHp
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Fislage, M, Brown, Z, Frank, J.
Deposit date:2017-07-06
Release date:2018-04-25
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A.
Nucleic Acids Res., 46, 2018
5O9Z
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BU of 5o9z by Molmil
Cryo-EM structure of a pre-catalytic human spliceosome primed for activation (B complex)
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, Homo sapiens RNA, U6 small nuclear 1 (RNU6-1), ...
Authors:Bertram, K, Kastner, B.
Deposit date:2017-06-20
Release date:2017-08-16
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation.
Cell, 170, 2017
5W75
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BU of 5w75 by Molmil
Crystal Structure of Reconstructed Bacterial Elongation Factor Node 168
Descriptor: Elongation factor Tu, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Ortlund, E.A.
Deposit date:2017-06-19
Release date:2018-04-25
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.298 Å)
Cite:Structural and Dynamics Comparison of Thermostability in Ancient, Modern, and Consensus Elongation Factor Tus.
Structure, 26, 2018
5O8W
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BU of 5o8w by Molmil
CRYSTAL STRUCTURE ANALYSIS OF THE YEAST ELONGATION FACTOR COMPLEX EEF1A:EEF1BA
Descriptor: Elongation factor 1-alpha, Elongation factor 1-beta, GLUTAMINE, ...
Authors:Wirth, C, Andersen, G.R, Hunte, C.
Deposit date:2017-06-14
Release date:2017-08-23
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Protein glutaminylation is a yeast-specific posttranslational modification of elongation factor 1A.
J. Biol. Chem., 292, 2017
5XJC
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BU of 5xjc by Molmil
Cryo-EM structure of the human spliceosome just prior to exon ligation at 3.6 angstrom
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Zhang, X, Yan, C, Hang, J, Finci, I.L, Lei, J, Shi, Y.
Deposit date:2017-04-30
Release date:2017-07-05
Last modified:2020-10-14
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:An Atomic Structure of the Human Spliceosome
Cell, 169, 2017
5NRL
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BU of 5nrl by Molmil
Structure of a pre-catalytic spliceosome.
Descriptor: 13 kDa ribonucleoprotein-associated protein, 23 kDa U4/U6.U5 small nuclear ribonucleoprotein component, 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component, ...
Authors:Plaschka, C, Lin, P.-C, Nagai, K.
Deposit date:2017-04-24
Release date:2017-05-31
Last modified:2023-05-24
Method:ELECTRON MICROSCOPY (7.2 Å)
Cite:Structure of a pre-catalytic spliceosome.
Nature, 546, 2017
5VH6
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BU of 5vh6 by Molmil
2.6 Angstrom Resolution Crystal Structure of N-terminal Fragment (residues 1-406) of Elongation Factor G from Bacillus subtilis.
Descriptor: CHLORIDE ION, Elongation factor G
Authors:Minasov, G, Shuvalova, L, Dubrovska, I, Kiryukhina, O, Grimshaw, S, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2017-04-12
Release date:2017-04-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:2.6 Angstrom Resolution Crystal Structure of N-terminal Fragment (residues 1-406) of Elongation Factor G from Bacillus subtilis.
To Be Published
5UYP
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BU of 5uyp by Molmil
70S ribosome bound with near-cognate ternary complex base-paired to A site codon, open 30S (Structure II-nc)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Loveland, A.B, Demo, G, Grigorieff, N, Korostelev, A.A.
Deposit date:2017-02-24
Release date:2017-06-07
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Ensemble cryo-EM elucidates the mechanism of translation fidelity
Nature, 546, 2017
5UYM
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BU of 5uym by Molmil
70S ribosome bound with cognate ternary complex base-paired to A site codon, closed 30S (Structure III)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Loveland, A.B, Demo, G, Grigorieff, N, Korostelev, A.A.
Deposit date:2017-02-24
Release date:2017-06-07
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Ensemble cryo-EM elucidates the mechanism of translation fidelity
Nature, 546, 2017
5UYQ
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BU of 5uyq by Molmil
70S ribosome bound with near-cognate ternary complex base-paired to A site codon, closed 30S (Structure III-nc)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Loveland, A.B, Demo, G, Grigorieff, N, Korostelev, A.A.
Deposit date:2017-02-24
Release date:2017-06-07
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Ensemble cryo-EM elucidates the mechanism of translation fidelity
Nature, 546, 2017
5UYL
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BU of 5uyl by Molmil
70S ribosome bound with cognate ternary complex base-paired to A site codon (Structure II)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Loveland, A.B, Demo, G, Grigorieff, N, Korostelev, A.A.
Deposit date:2017-02-24
Release date:2017-06-14
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Ensemble cryo-EM elucidates the mechanism of translation fidelity.
Nature, 546, 2017
5UYN
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BU of 5uyn by Molmil
70S ribosome bound with near-cognate ternary complex not base-paired to A site codon (Structure I-nc)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Loveland, A.B, Demo, G, Grigorieff, N, Korostelev, A.A.
Deposit date:2017-02-24
Release date:2017-06-07
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Ensemble cryo-EM elucidates the mechanism of translation fidelity
Nature, 546, 2017
5UYK
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BU of 5uyk by Molmil
70S ribosome bound with cognate ternary complex not base-paired to A site codon (Structure I)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Loveland, A.B, Demo, G, Grigorieff, N, Korostelev, A.A.
Deposit date:2017-02-24
Release date:2017-06-07
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Ensemble cryo-EM elucidates the mechanism of translation fidelity
Nature, 546, 2017
5MQF
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BU of 5mqf by Molmil
Cryo-EM structure of a human spliceosome activated for step 2 of splicing (C* complex)
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, ATP-dependent RNA helicase DHX8, Cell division cycle 5-like protein, ...
Authors:Bertram, K, Hartmuth, K, Kastner, B.
Deposit date:2016-12-20
Release date:2017-03-22
Last modified:2018-11-21
Method:ELECTRON MICROSCOPY (5.9 Å)
Cite:Cryo-EM structure of a human spliceosome activated for step 2 of splicing.
Nature, 542, 2017
5MQ0
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BU of 5mq0 by Molmil
Structure of a spliceosome remodeled for exon ligation
Descriptor: 3'-EXON OF UBC4 PRE-MRNA, BOUND BY PRP22 HELICASE, 5'-EXON OF UBC4 PRE-MRNA, ...
Authors:Fica, S.M, Oubridge, C, Galej, W.P, Wilkinson, M.E, Newman, A.J, Bai, X.-C, Nagai, K.
Deposit date:2016-12-19
Release date:2017-01-18
Last modified:2020-10-07
Method:ELECTRON MICROSCOPY (4.17 Å)
Cite:Structure of a spliceosome remodelled for exon ligation.
Nature, 542, 2017
5MPS
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BU of 5mps by Molmil
Structure of a spliceosome remodeled for exon ligation
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ...
Authors:Fica, S.M, Oubridge, C, Galej, W.P, Wilkinson, M.E, Newman, A.J, Bai, X.-C, Nagai, K.
Deposit date:2016-12-18
Release date:2017-01-18
Last modified:2020-10-07
Method:ELECTRON MICROSCOPY (3.85 Å)
Cite:Structure of a spliceosome remodelled for exon ligation.
Nature, 542, 2017
5WSG
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BU of 5wsg by Molmil
Cryo-EM structure of the Catalytic Step II spliceosome (C* complex) at 4.0 angstrom resolution
Descriptor: 3'-exon-intron, 3'-intron-lariat, 5'-exon, ...
Authors:Yan, C, Wan, R, Bai, R, Huang, G, Shi, Y.
Deposit date:2016-12-07
Release date:2017-01-25
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structure of a yeast step II catalytically activated spliceosome
Science, 355, 2017
5MI3
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BU of 5mi3 by Molmil
Structure of phosphorylated translation elongation factor EF-Tu from E. coli
Descriptor: Elongation factor Tu 1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Talavera, A, Hendrix, J, Versees, W, De Gieter, S, Castro-Roa, D, Jurenas, D, Van Nerom, K, Vandenberk, N, Barth, A, De Greve, H, Hofkens, J, Zenkin, N, Loris, R, Garcia-Pino, A.
Deposit date:2016-11-27
Release date:2017-12-20
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Phosphorylation decelerates conformational dynamics in bacterial translation elongation factors.
Sci Adv, 4, 2018
5MI8
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BU of 5mi8 by Molmil
Structure of the phosphomimetic mutant of EF-Tu T383E
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, BETA-MERCAPTOETHANOL, ...
Authors:Talavera, A, Hendrix, J, Versees, W, De Gieter, S, Castro-Roa, D, Jurenas, D, Van Nerom, K, Vandenberk, N, Barth, A, De Greve, H, Hofkens, J, Zenkin, N, Loris, R, Garcia-Pino, A.
Deposit date:2016-11-27
Release date:2017-12-20
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Phosphorylation decelerates conformational dynamics in bacterial translation elongation factors.
Sci Adv, 4, 2018
5MI9
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BU of 5mi9 by Molmil
Structure of the phosphomimetic mutant of the elongation factor EF-Tu T62E
Descriptor: Elongation factor Tu 1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Talavera, A, Hendrix, J, Versees, W, De Gieter, S, Castro-Roa, D, Jurenas, D, Van Nerom, K, Vandenberk, N, Barth, A, De Greve, H, Hofkens, J, Zenkin, N, Loris, R, Garcia-Pino, A.
Deposit date:2016-11-27
Release date:2017-12-20
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Phosphorylation decelerates conformational dynamics in bacterial translation elongation factors.
Sci Adv, 4, 2018
5H7L
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BU of 5h7l by Molmil
Complex of Elongation factor 2-50S ribosomal protein L12
Descriptor: 50S ribosomal protein L12, Elongation factor 2, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER
Authors:Tanzawa, T, Kato, K, Uchiumi, T, Yao, M.
Deposit date:2016-11-18
Release date:2018-02-21
Last modified:2018-05-02
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The C-terminal helix of ribosomal P stalk recognizes a hydrophobic groove of elongation factor 2 in a novel fashion
Nucleic Acids Res., 46, 2018
5H7K
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BU of 5h7k by Molmil
Crystal structure of Elongation factor 2 GDP-form
Descriptor: Elongation factor 2, GUANOSINE-5'-DIPHOSPHATE
Authors:Tanzawa, T, Kato, K, Uchiumi, T, Yao, M.
Deposit date:2016-11-18
Release date:2018-02-21
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.599 Å)
Cite:The C-terminal helix of ribosomal P stalk recognizes a hydrophobic groove of elongation factor 2 in a novel fashion
Nucleic Acids Res., 46, 2018

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数据于2024-06-12公开中

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