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7D7S
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BU of 7d7s by Molmil
HIV-1 SF2 Nef in complex with the Fyn SH3 R96I mutant
Descriptor: Protein Nef, Tyrosine-protein kinase Fyn
Authors:Aldehaiman, A, Shahul Hamed, U.F, Arold, S.T.
Deposit date:2020-10-05
Release date:2020-11-18
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.32 Å)
Cite:Synergy and allostery in ligand binding by HIV-1 Nef.
Biochem.J., 478, 2021
2ISW
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BU of 2isw by Molmil
Structure of Giardia fructose-1,6-biphosphate aldolase in complex with phosphoglycolohydroxamate
Descriptor: PHOSPHOGLYCOLOHYDROXAMIC ACID, Putative fructose-1,6-bisphosphate aldolase, ZINC ION
Authors:Galkin, A, Herzberg, O.
Deposit date:2006-10-18
Release date:2006-12-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Characterization, kinetics, and crystal structures of fructose-1,6-bisphosphate aldolase from the human parasite, Giardia lamblia.
J.Biol.Chem., 282, 2007
2O5D
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BU of 2o5d by Molmil
Thiazolone-acylsulfonamides as novel HCV NS5B polymerase allosteric inhibitors: Convergence of structure-based drug design and X-ray crystallographic study
Descriptor: (2S)-2-({(5Z)-5-[(5-ETHYL-2-FURYL)METHYLENE]-4-OXO-4,5-DIHYDRO-1,3-THIAZOL-2-YL}AMINO)-2-(4-FLUOROPHENYL)-N-[(4-NITROPHENYL)SULFONYL]ACETAMIDE, HCV
Authors:Yao, N.
Deposit date:2006-12-05
Release date:2007-02-20
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Thiazolone-acylsulfonamides as novel HCV NS5B polymerase allosteric inhibitors: Convergence of structure-based drug design and X-ray crystallographic study.
Bioorg.Med.Chem.Lett., 17, 2007
4P4K
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BU of 4p4k by Molmil
Structural Basis of Chronic Beryllium Disease: Bridging the Gap Between allergic hypersensitivity and auto immunity
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, BERYLLIUM, HLA class II histocompatibility antigen, ...
Authors:Clayton, G.M, Crawford, F, Kappler, J.W.
Deposit date:2014-03-12
Release date:2014-07-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis of chronic beryllium disease: linking allergic hypersensitivity and autoimmunity.
Cell, 158, 2014
2I3C
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BU of 2i3c by Molmil
Crystal Structure of an Aspartoacylase from Homo Sapiens
Descriptor: Aspartoacylase, PHOSPHATE ION, ZINC ION
Authors:Bitto, E, Wesenberg, G.E, Phillips Jr, G.N, Mccoy, J.G, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG)
Deposit date:2006-08-17
Release date:2006-08-29
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of aspartoacylase, the brain enzyme impaired in Canavan disease.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2CKM
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BU of 2ckm by Molmil
Torpedo californica acetylcholinesterase complexed with alkylene- linked bis-tacrine dimer (7 carbon linker)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINESTERASE, N,N'-DI-1,2,3,4-TETRAHYDROACRIDIN-9-YLHEPTANE-1,7-DIAMINE
Authors:Brumshtein, B, Rydberg, E.H, Greenblatt, H.M, Wong, D.M, Shaya, D, Williams, L.D, Carlier, P.R, Pang, Y.P, Silman, I, Sussman, J.L.
Deposit date:2006-04-20
Release date:2006-09-04
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Complexes of alkylene-linked tacrine dimers with Torpedo californica acetylcholinesterase: Binding of Bis5-tacrine produces a dramatic rearrangement in the active-site gorge.
J. Med. Chem., 49, 2006
3BY0
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BU of 3by0 by Molmil
Crystal structure of Siderocalin (NGAL, Lipocalin 2) W79A-R81A complexed with Ferric Enterobactin
Descriptor: 2,3-DIHYDROXY-BENZOIC ACID, 2-(2,3-DIHYDROXY-BENZOYLAMINO)-3-HYDROXY-PROPIONIC ACID, FE (III) ION, ...
Authors:Clifton, M.C, Pizzaro, J.C, Strong, R.K.
Deposit date:2008-01-15
Release date:2008-09-09
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.572 Å)
Cite:The siderocalin/enterobactin interaction: a link between mammalian immunity and bacterial iron transport.
J.Am.Chem.Soc., 130, 2008
2FQL
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BU of 2fql by Molmil
Crystal structure of trimeric frataxin from the yeast Saccharomyces cerevisiae
Descriptor: Frataxin homolog, mitochondrial
Authors:Al-Karadaghi, S, Karlberg, T.
Deposit date:2006-01-18
Release date:2006-11-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:The structures of frataxin oligomers reveal the mechanism for the delivery and detoxification of iron.
Structure, 14, 2006
2GU2
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BU of 2gu2 by Molmil
Crystal Structure of an Aspartoacylase from Rattus norvegicus
Descriptor: Aspa protein, SULFATE ION, ZINC ION
Authors:Bitto, E, Wesenberg, G.E, Phillips Jr, G.N, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG)
Deposit date:2006-04-28
Release date:2006-06-20
Last modified:2022-12-21
Method:X-RAY DIFFRACTION (1.805 Å)
Cite:Structure of aspartoacylase, the brain enzyme impaired in Canavan disease.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2FRX
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BU of 2frx by Molmil
Crystal structure of YebU, a m5C RNA methyltransferase from E.coli
Descriptor: Hypothetical protein yebU
Authors:Erlandsen, H, Nordlund, P, Hallberg, B.M, Johnson, K.A, Ericsson, U.B.
Deposit date:2006-01-20
Release date:2006-08-29
Last modified:2018-05-23
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The structure of the RNA m5C methyltransferase YebU from Escherichia coli reveals a C-terminal RNA-recruiting PUA domain
J.Mol.Biol., 360, 2006
5L88
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BU of 5l88 by Molmil
AFAMIN ANTIBODY FRAGMENT, N14 FAB, L1- GLYCOSILATED, CRYSTAL FORM I, non-parsimonious model
Descriptor: 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, Anti-afamin antibody N14, Fab fragment, ...
Authors:Rupp, B, Naschberger, A.
Deposit date:2016-06-07
Release date:2016-08-03
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:The N14 anti-afamin antibody Fab: a rare VL1 CDR glycosylation, crystallographic re-sequencing, molecular plasticity and conservative versus enthusiastic modelling.
Acta Crystallogr D Struct Biol, 72, 2016
5L9D
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BU of 5l9d by Molmil
AFAMIN ANTIBODY FRAGMENT, N14 FAB, L1- GLYCOSYLATED, CRYSTAL FORM I, parsimonious model
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, DI(HYDROXYETHYL)ETHER, ...
Authors:Rupp, B, Naschberger, A.
Deposit date:2016-06-10
Release date:2016-08-03
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:The N14 anti-afamin antibody Fab: a rare VL1 CDR glycosylation, crystallographic re-sequencing, molecular plasticity and conservative versus enthusiastic modelling.
Acta Crystallogr D Struct Biol, 72, 2016
2PTL
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BU of 2ptl by Molmil
THREE-DIMENSIONAL SOLUTION STRUCTURE OF AN IMMUNOGLOBULIN LIGHT CHAIN-BINDING DOMAIN OF PROTEIN L. COMPARISON WITH THE IGG-BINDING DOMAINS OF PROTEIN G
Descriptor: PROTEIN L
Authors:Wikstroem, M, Drakenberg, T, Forsen, S, Sjoebring, U, Bjoerck, L.
Deposit date:1994-08-12
Release date:1994-10-15
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Three-dimensional solution structure of an immunoglobulin light chain-binding domain of protein L. Comparison with the IgG-binding domains of protein G.
Biochemistry, 33, 1994
5L7X
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BU of 5l7x by Molmil
Afamin antibody fragment, N14 Fab, L1- glycosylated, crystal form II
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, Mouse Antibody Fab Fragment, ...
Authors:Rupp, B, Naschberger, A.
Deposit date:2016-06-04
Release date:2016-07-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:The N14 anti-afamin antibody Fab: a rare VL1 CDR glycosylation, crystallographic re-sequencing, molecular plasticity and conservative versus enthusiastic modelling.
Acta Crystallogr D Struct Biol, 72, 2016
1A0L
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BU of 1a0l by Molmil
HUMAN BETA-TRYPTASE: A RING-LIKE TETRAMER WITH ACTIVE SITES FACING A CENTRAL PORE
Descriptor: (2S)-3-(4-carbamimidoylphenyl)-2-hydroxypropanoic acid, BETA-TRYPTASE
Authors:Pereira, P.J.B, Bergner, A, Macedo-Ribeiro, S, Huber, R, Matschiner, G, Fritz, H, Sommerhoff, C.P, Bode, W.
Deposit date:1997-12-03
Release date:1999-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Human beta-tryptase is a ring-like tetramer with active sites facing a central pore.
Nature, 392, 1998
2NWD
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BU of 2nwd by Molmil
Structure of chemically synthesized human lysozyme at 1 Angstrom resolution
Descriptor: Lysozyme C
Authors:Durek, T, Torbeev, V.Y, Kent, S.B.H.
Deposit date:2006-11-14
Release date:2006-12-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.04 Å)
Cite:Convergent chemical synthesis and high-resolution x-ray structure of human lysozyme.
Proc.Natl.Acad.Sci.Usa, 104, 2007
1BE6
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BU of 1be6 by Molmil
TRANS-CINNAMOYL-SUBTILISIN IN ANHYDROUS ACETONITRILE
Descriptor: ACETONITRILE, CALCIUM ION, PHENYLETHYLENECARBOXYLIC ACID, ...
Authors:Schmitke, J.L, Stern, L.J, Klibanov, A.M.
Deposit date:1998-05-20
Release date:1998-10-14
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Comparison of x-ray crystal structures of an acyl-enzyme intermediate of subtilisin Carlsberg formed in anhydrous acetonitrile and in water.
Proc.Natl.Acad.Sci.USA, 95, 1998
3CBC
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BU of 3cbc by Molmil
Crystal structure of Siderocalin (NGAL, Lipocalin 2) Y106F complexed with Ferric Enterobactin
Descriptor: 2-(2,3-DIHYDROXY-BENZOYLAMINO)-3-HYDROXY-PROPIONIC ACID, GLYCEROL, Neutrophil gelatinase-associated lipocalin, ...
Authors:Clifton, M.C, Pizaro, J.C, Strong, R.K.
Deposit date:2008-02-21
Release date:2008-09-09
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:The siderocalin/enterobactin interaction: a link between mammalian immunity and bacterial iron transport.
J.Am.Chem.Soc., 130, 2008
1914
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BU of 1914 by Molmil
SIGNAL RECOGNITION PARTICLE ALU RNA BINDING HETERODIMER, SRP9/14
Descriptor: BETA-MERCAPTOETHANOL, PHOSPHATE ION, SIGNAL RECOGNITION PARTICLE 9/14 FUSION PROTEIN
Authors:Birse, D, Kapp, U, Strub, K, Cusack, S, Aberg, A.
Deposit date:1997-11-13
Release date:1998-12-30
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:The crystal structure of the signal recognition particle Alu RNA binding heterodimer, SRP9/14.
EMBO J., 16, 1997
1BE8
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BU of 1be8 by Molmil
TRANS-CINNAMOYL-SUBTILISIN IN WATER
Descriptor: CALCIUM ION, PHENYLETHYLENECARBOXYLIC ACID, SUBTILISIN CARLSBERG
Authors:Schmitke, J.L, Stern, L.J, Klibanov, A.M.
Deposit date:1998-05-20
Release date:1998-10-28
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Comparison of x-ray crystal structures of an acyl-enzyme intermediate of subtilisin Carlsberg formed in anhydrous acetonitrile and in water.
Proc.Natl.Acad.Sci.USA, 95, 1998
2R4P
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BU of 2r4p by Molmil
Crystal structure of the long-chain fatty acid transporter FadL mutant G212E
Descriptor: LAURYL DIMETHYLAMINE-N-OXIDE, Long-chain fatty acid transport protein
Authors:Hearn, E.M, Patel, D.R, Lepore, B.W, Indic, M, van den Berg, B.
Deposit date:2007-08-31
Release date:2008-09-16
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Transmembrane passage of hydrophobic compounds through a protein channel wall
Nature, 458, 2009
2R4L
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BU of 2r4l by Molmil
Crystal structure of the long-chain fatty acid transporter FadL mutant P34A
Descriptor: LAURYL DIMETHYLAMINE-N-OXIDE, Long-chain fatty acid transport protein
Authors:Hearn, E.M, Patel, D.R, Lepore, B.W, Indic, M, van den Berg, B.
Deposit date:2007-08-31
Release date:2008-09-16
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Transmembrane passage of hydrophobic compounds through a protein channel wall
Nature, 458, 2009
2R4N
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BU of 2r4n by Molmil
Crystal structure of the long-chain fatty acid transporter FadL mutant N33A
Descriptor: LAURYL DIMETHYLAMINE-N-OXIDE, Long-chain fatty acid transport protein
Authors:Hearn, E.M, Patel, D.R, Lepore, B.W, Indic, M, van den Berg, B.
Deposit date:2007-08-31
Release date:2008-09-16
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Transmembrane passage of hydrophobic compounds through a protein channel wall
Nature, 458, 2009
2R4O
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BU of 2r4o by Molmil
Crystal structure of the long-chain fatty acid transporter FadL mutant delta NPA
Descriptor: LAURYL DIMETHYLAMINE-N-OXIDE, Long-chain fatty acid transport protein
Authors:Hearn, E.M, Patel, D.R, Lepore, B.W, Indic, M, van den Berg, B.
Deposit date:2007-08-31
Release date:2008-09-16
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Transmembrane passage of hydrophobic compounds through a protein channel wall
Nature, 458, 2009
2R88
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Crystal structure of the long-chain fatty acid transporter FadL mutant delta S3 kink
Descriptor: Long-chain fatty acid transport protein
Authors:Hearn, E.M, Patel, D.R, Lepore, B.W, Indic, M, van den Berg, B.
Deposit date:2007-09-10
Release date:2008-09-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Transmembrane passage of hydrophobic compounds through a protein channel wall
Nature, 458, 2009

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