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7XBR
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BU of 7xbr by Molmil
Crystal structure of phosphorylated AtMKK5
Descriptor: Mitogen-activated protein kinase kinase 5
Authors:Pei, C.J, Luo, Z.P, Wu, J.W, Wang, Z.X.
Deposit date:2022-03-22
Release date:2023-02-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of the phosphorylated Arabidopsis MKK5 reveals activation mechanism of MAPK kinases.
Acta Biochim.Biophys.Sin., 54, 2022
5CL6
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Alkylpurine DNA glycosylase AlkD bound to DNA containing a 3-methyladenine analog or DNA containing an abasic site and a free nucleobase (33% substrate/67% product at 72 hours)
Descriptor: 7-methyl-3H-imidazo[4,5-c]pyridin-4-amine, AlkD, DNA (5'-D(*CP*CP*CP*GP*AP*(DZM)P*AP*GP*TP*CP*CP*G)-3'), ...
Authors:Mullins, E.A, Eichman, B.F.
Deposit date:2015-07-16
Release date:2015-10-28
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.541 Å)
Cite:The DNA glycosylase AlkD uses a non-base-flipping mechanism to excise bulky lesions.
Nature, 527, 2015
1KOY
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BU of 1koy by Molmil
NMR structure of DFF-C domain
Descriptor: DNA fragmentation factor alpha subunit
Authors:Fukushima, K, Kikuchi, J, Koshiba, S, Kigawa, T, Kuroda, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2001-12-25
Release date:2002-09-04
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the DFF-C domain of DFF45/ICAD. A structural basis for the regulation of apoptotic DNA fragmentation.
J.Mol.Biol., 321, 2002
5CL5
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Alkylpurine DNA glycosylase AlkD bound to DNA containing a 3-methyladenine analog or DNA containing an abasic site and a free nucleobase (51% substrate/49% product at 48 hours)
Descriptor: 7-methyl-3H-imidazo[4,5-c]pyridin-4-amine, AlkD, DNA (5'-D(*CP*CP*CP*GP*AP*(DZM)P*AP*GP*TP*CP*CP*G)-3'), ...
Authors:Mullins, E.A, Eichman, B.F.
Deposit date:2015-07-16
Release date:2015-10-28
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.569 Å)
Cite:The DNA glycosylase AlkD uses a non-base-flipping mechanism to excise bulky lesions.
Nature, 527, 2015
1D2Y
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BU of 1d2y by Molmil
N-TERMINAL DOMAIN CORE METHIONINE MUTATION
Descriptor: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, LYSOZYME
Authors:Gassner, N.C, Matthews, B.W.
Deposit date:1999-09-28
Release date:1999-10-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Use of differentially substituted selenomethionine proteins in X-ray structure determination.
Acta Crystallogr.,Sect.D, 55, 1999
1KTC
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BU of 1ktc by Molmil
The Structure of alpha-N-Acetylgalactosaminidase
Descriptor: 2-acetamido-2-deoxy-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Garman, S.C, Hannick, L, Zhu, A, Garboczi, D.N.
Deposit date:2002-01-15
Release date:2002-03-15
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The 1.9 A structure of alpha-N-acetylgalactosaminidase: molecular basis of glycosidase deficiency diseases.
Structure, 10, 2002
4M28
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BU of 4m28 by Molmil
UDP-Glucose Pyrophosphorylase from Leishmania major in complex with UTP analog dUpCpp
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]uridine, UDP-glucose pyrophosphorylase
Authors:Fuehring, J.I, Routier, F.H, Lamerz, A.-C, Baruch, P, Gerardy-Schahn, R, Fedorov, R.
Deposit date:2013-08-05
Release date:2014-01-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Catalytic mechanism and allosteric regulation of UDP-glucose pyrophosphorylase from Leishmania major
ACS CATALYSIS, 3, 2013
1D4A
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BU of 1d4a by Molmil
CRYSTAL STRUCTURE OF HUMAN NAD[P]H-QUINONE OXIDOREDUCTASE AT 1.7 A RESOLUTION
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, QUINONE REDUCTASE
Authors:Faig, M, Bianchet, M.A, Chen, S, Winski, S, Ross, D, Amzel, L.M.
Deposit date:1999-10-01
Release date:1999-10-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structures of recombinant human and mouse NAD(P)H:quinone oxidoreductases: species comparison and structural changes with substrate binding and release.
Proc.Natl.Acad.Sci.USA, 97, 2000
7WVH
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BU of 7wvh by Molmil
Structure of NAD+ glycohydrolase/Streptolysin O complex from Group A streptococcus
Descriptor: NAD+-glycohydrolase, Streptolysin O
Authors:Tsai, W.-J, Wang, S.-Y.
Deposit date:2022-02-10
Release date:2023-02-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structural basis underlying the synergism of NADase and SLO during group A Streptococcus infection.
Commun Biol, 6, 2023
7WZ9
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BU of 7wz9 by Molmil
HSA-In agent complex
Descriptor: 16-chloranyl-~{N},~{N}-dimethyl-15-thia-1$l^{4},12$l^{4},13-triaza-16$l^{4}-indatetracyclo[8.6.0.0^{2,7}.0^{12,16}]hexadeca-1,3,5,7,9,11,13-heptaen-14-amine, PALMITIC ACID, Serum albumin
Authors:Zhang, Z.L, Yang, F.
Deposit date:2022-02-17
Release date:2023-02-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.83 Å)
Cite:Structure of HSA-In agent complex
To Be Published
1KXT
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BU of 1kxt by Molmil
Camelid VHH Domains in Complex with Porcine Pancreatic alpha-Amylase
Descriptor: ALPHA-AMYLASE, PANCREATIC, CALCIUM ION, ...
Authors:Desmyter, A, Spinelli, S, Payan, F, Lauwereys, M, Wyns, L, Muyldermans, S, Cambillau, C.
Deposit date:2002-02-01
Release date:2002-06-19
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Three camelid VHH domains in complex with porcine pancreatic alpha-amylase. Inhibition and versatility of binding topology.
J.Biol.Chem., 277, 2002
3K1H
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BU of 3k1h by Molmil
Crystal structure of HP1076 from H.pylori
Descriptor: Putative uncharacterized protein
Authors:Lam, W.W.L, Ling, T.K.W, Woo, E.J, Au, S.W.N.
Deposit date:2009-09-28
Release date:2010-06-30
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Molecular interaction of flagellar export chaperone FliS and cochaperone HP1076 in Helicobacter pylori
Faseb J., 24, 2010
3BDW
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BU of 3bdw by Molmil
Human CD94/NKG2A
Descriptor: NKG2-A/NKG2-B type II integral membrane protein, Natural killer cells antigen CD94
Authors:Sullivan, L.C, Clements, C.S.
Deposit date:2007-11-15
Release date:2008-01-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The Heterodimeric Assembly of the CD94-NKG2 Receptor Family and Implications for Human Leukocyte Antigen-E Recognition
Immunity, 27, 2007
6T59
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BU of 6t59 by Molmil
Structure of rabbit 80S ribosome translating beta-tubulin in complex with tetratricopeptide protein 5 and nascent chain-associated complex
Descriptor: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Lin, Z, Gasic, I, Chandrasekaran, V, Peters, N, Shao, S, Ramakrishnan, V, Mitchison, T.J, Hegde, R.S.
Deposit date:2019-10-15
Release date:2019-11-27
Last modified:2020-01-15
Method:ELECTRON MICROSCOPY (3.11 Å)
Cite:TTC5 mediates autoregulation of tubulin via mRNA degradation.
Science, 367, 2020
6HX8
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BU of 6hx8 by Molmil
Tubulin-STX3451 complex
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Dohle, W, Prota, A.E, Menchon, G, Hamel, E, Steinmetz, M.O, Potter, B.V.L.
Deposit date:2018-10-16
Release date:2019-02-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.402 Å)
Cite:Tetrahydroisoquinoline Sulfamates as Potent Microtubule Disruptors: Synthesis, Antiproliferative and Antitubulin Activity of Dichlorobenzyl-Based Derivatives, and a Tubulin Cocrystal Structure.
ACS Omega, 4, 2019
6F9F
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BU of 6f9f by Molmil
Model of the Rift Valley fever virus glycoprotein pentamer
Descriptor: Glycoprotein
Authors:Halldorsson, S, Bowden, T.A, Huiskonen, J.T.
Deposit date:2017-12-14
Release date:2018-01-31
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (13.3 Å)
Cite:Shielding and activation of a viral membrane fusion protein.
Nat Commun, 9, 2018
1KCW
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BU of 1kcw by Molmil
X-RAY CRYSTAL STRUCTURE OF HUMAN CERULOPLASMIN AT 3.0 ANGSTROMS
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CERULOPLASMIN, COPPER (II) ION, ...
Authors:Card, G.L, Zaitsev, V.N, Lindley, P.F.
Deposit date:1996-09-25
Release date:1997-02-12
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:The X-ray structure of human serum ceruloplasmin at 3.1 angstrom: Nature of the copper centres.
J.Biol.Inorg.Chem., 1, 1996
3B2D
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BU of 3b2d by Molmil
Crystal structure of human RP105/MD-1 complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CD180 antigen, ...
Authors:Ohto, U, Shimizu, T.
Deposit date:2011-07-29
Release date:2011-11-09
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structures of Mouse and Human RP105/MD-1 Complexes Reveal Unique Dimer Organization of the Toll-Like Receptor Family.
J.Mol.Biol., 413, 2011
6GEE
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BU of 6gee by Molmil
TEAD4 (216-434);E263A COMPLEXED WITH YAP PEPTIDE (60-100); S94A AND MYRISTOATE (COVALENTLY BOUND) AT 1.96A (P41212 CRYSTAL FORM); MYRISTOYLATION WAS DONE BY ADDING MYR-COA
Descriptor: MYRISTIC ACID, Transcriptional coactivator YAP1, Transcriptional enhancer factor TEF-3
Authors:Kallen, J.
Deposit date:2018-04-26
Release date:2018-09-19
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Adaptation of the bound intrinsically disordered protein YAP to mutations at the YAP:TEAD interface.
Protein Sci., 27, 2018
1XVA
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BU of 1xva by Molmil
METHYLTRANSFERASE
Descriptor: ACETATE ION, GLYCINE N-METHYLTRANSFERASE, S-ADENOSYLMETHIONINE
Authors:Fu, Z, Hu, Y, Konishi, K, Takata, Y, Ogawa, H, Gomi, T, Fujioka, M, Takusagawa, F.
Deposit date:1996-07-20
Release date:1997-01-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of glycine N-methyltransferase from rat liver.
Biochemistry, 35, 1996
6G3W
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BU of 6g3w by Molmil
Crystal structure of the BIR3 - SERK2 complex from Arabidopsis thaliana.
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ...
Authors:Hothorn, M, Hohmann, U.
Deposit date:2018-03-26
Release date:2018-04-04
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The SERK3 elongated allele defines a role for BIR ectodomains in brassinosteroid signalling.
Nat Plants, 4, 2018
1CEN
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BU of 1cen by Molmil
CELLULASE (CELC) MUTANT WITH GLU 140 REPLACED BY GLN COMPLEXED WITH CELLOHEXAOSE
Descriptor: CELLULASE CELC, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose
Authors:Dominguez, R, Alzari, P.M.
Deposit date:1995-12-04
Release date:1996-04-03
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The crystal structure of a family 5 endoglucanase mutant in complexed and uncomplexed forms reveals an induced fit activation mechanism.
J.Mol.Biol., 257, 1996
4HGK
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BU of 4hgk by Molmil
Shark IgNAR variable domain
Descriptor: Serum albumin, shark V-NAR antibody
Authors:Olland, A.O, Kovalenko, O.V, Svenson, K, King, D.
Deposit date:2012-10-08
Release date:2013-05-08
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.04 Å)
Cite:Atypical Antigen Recognition Mode of a Shark Immunoglobulin New Antigen Receptor (IgNAR) Variable Domain Characterized by Humanization and Structural Analysis.
J.Biol.Chem., 288, 2013
1KG5
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BU of 1kg5 by Molmil
Crystal structure of the K142Q mutant of E.coli MutY (core fragment)
Descriptor: A/G-specific adenine glycosylase, GLYCEROL, IRON/SULFUR CLUSTER, ...
Authors:Gilboa, R, Kilshtein, A, Zharkov, D.O, Kycia, J.H, Gerchman, S.E, Grollman, A.P, Shoham, G.
Deposit date:2001-11-26
Release date:2002-11-26
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Analysis of the E.coli MutY DNA glycosylase structure and function by site-directed mutagenesis
To be Published
1G7M
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BU of 1g7m by Molmil
CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME (HEL) COMPLEXED WITH THE MUTANT ANTI-HEL MONOCLONAL ANTIBODY D1.3 (VLW92V)
Descriptor: ANTI-HEN EGG WHITE LYSOZYME MONOCLONAL ANTIBODY D1.3, LYSOZYME C
Authors:Sundberg, E.J, Urrutia, M, Braden, B.C, Isern, J, Mariuzza, R.A.
Deposit date:2000-11-10
Release date:2000-11-22
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Estimation of the hydrophobic effect in an antigen-antibody protein-protein interface.
Biochemistry, 39, 2000

224004

数据于2024-08-21公开中

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