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1T7P
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T7 DNA POLYMERASE COMPLEXED TO DNA PRIMER/TEMPLATE,A NUCLEOSIDE TRIPHOSPHATE, AND ITS PROCESSIVITY FACTOR THIOREDOXIN
Descriptor: 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(P*CP*CP*TP*TP*GP*GP*CP*AP*CP*TP*GP*GP*C)-3'), DNA (5'-D(P*GP*CP*CP*AP*GP*TP*GP*CP*CP*AP*2DA)-3'), ...
Authors:Doublie, S, Tabor, S, Long, A.M, Richardson, C.C, Ellenberger, T.
Deposit date:1997-09-24
Release date:1998-02-25
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 A resolution.
Nature, 391, 1998
1TJG
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Crystal Structure of the broadly neutralizing anti-HIV-1 antibody 2F5 in complex with a gp41 7mer epitope
Descriptor: 1,2-ETHANEDIOL, Envelope glycoprotein GP41, FAB 2F5 Heavy Chain, ...
Authors:Ofek, G, Tang, M, Sambor, A, Katinger, H, Mascola, J.R, Wyatt, R, Kwong, P.D.
Deposit date:2004-06-04
Release date:2004-10-05
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and mechanistic analysis of the Anti-Human Immunodeficiency Virus Type 1 antibody 2F5 in complex with its gp41 epitope
J.Virol., 78, 2004
1TKI
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AUTOINHIBITED SERINE KINASE DOMAIN OF THE GIANT MUSCLE PROTEIN TITIN
Descriptor: TITIN
Authors:Mayans, M.O, Gautel, M, Wilmanns, M.
Deposit date:1998-05-29
Release date:1999-06-08
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for activation of the titin kinase domain during myofibrillogenesis.
Nature, 395, 1998
1TLV
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Structure of the native and inactive LicT PRD from B. subtilis
Descriptor: Transcription antiterminator licT
Authors:Graille, M, Zhou, C.-Z, Receveur-Brechot, V, Collinet, B, Declerck, N, van Tilbeurgh, H.
Deposit date:2004-06-10
Release date:2005-02-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Activation of the LicT Transcriptional Antiterminator Involves a Domain Swing/Lock Mechanism Provoking Massive Structural Changes
J.Biol.Chem., 280, 2005
1TCY
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DISSECTION OF THE FUNCTIONAL ROLE OF STRUCTURAL ELEMENTS OF TYROSINE-63 IN THE CATALYTIC ACTION OF HUMAN LYSOZYME
Descriptor: HUMAN LYSOZYME
Authors:Harata, K, Muraki, M, Jigami, Y.
Deposit date:1992-08-06
Release date:1993-01-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Dissection of the functional role of structural elements of tyrosine-63 in the catalytic action of human lysozyme.
Biochemistry, 31, 1992
1TD6
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Crystal structure of the conserved hypothetical protein MP506/MPN330 (gi: 1674200)from Mycoplasma pneumoniae
Descriptor: Hypothetical protein MG237 homolog
Authors:Das, D, Oganesyan, N, Yokota, H, Jancarik, J, Kim, R, Kim, S.H, Berkeley Structural Genomics Center (BSGC)
Deposit date:2004-05-21
Release date:2004-12-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the conserved hypothetical protein MPN330 (GI: 1674200) from Mycoplasma pneumoniae.
Proteins, 58, 2004
1TFA
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OVOTRANSFERRIN, N-TERMINAL LOBE, APO FORM
Descriptor: PROTEIN (OVOTRANSFERRIN), SULFATE ION
Authors:Mizutani, K, Yamashita, H, Mikami, B, Hirose, M.
Deposit date:1999-01-07
Release date:1999-01-13
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Alternative structural state of transferrin. The crystallographic analysis of iron-loaded but domain-opened ovotransferrin N-lobe.
J.Biol.Chem., 274, 1999
1TFH
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EXTRACELLULAR DOMAIN OF HUMAN TISSUE FACTOR
Descriptor: HUMAN TISSUE FACTOR
Authors:Huang, M, Syed, R, Stura, E.A, Stone, M.J, Stefanko, R.S, Ruf, W, Edgington, T.S, Wilson, I.A.
Deposit date:1997-04-10
Release date:1998-02-25
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The mechanism of an inhibitory antibody on TF-initiated blood coagulation revealed by the crystal structures of human tissue factor, Fab 5G9 and TF.G9 complex.
J.Mol.Biol., 275, 1998
1TGJ
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HUMAN TRANSFORMING GROWTH FACTOR-BETA 3, CRYSTALLIZED FROM DIOXANE
Descriptor: 1,4-DIETHYLENE DIOXIDE, TRANSFORMING GROWTH FACTOR-BETA 3
Authors:Mittl, P.R.E, Priestle, J.P, Gruetter, M.G.
Deposit date:1996-07-09
Release date:1997-01-11
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure of TGF-beta 3 and comparison to TGF-beta 2: implications for receptor binding.
Protein Sci., 5, 1996
1TJL
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Crystal structure of transcription factor DksA from E. coli
Descriptor: DnaK suppressor protein, ZINC ION
Authors:Perederina, A, Svetlov, V, Vassylyeva, M.N, Artsimovitch, I, Yokoyama, S, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2004-06-06
Release date:2004-09-07
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Regulation through the secondary channel--structural framework for ppGpp-DksA synergism during transcription
Cell(Cambridge,Mass.), 118, 2004
1TKX
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CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH GW490745
Descriptor: 4-[(CYCLOPROPYLETHYNYL)OXY]-6-FLUORO-3-ISOPROPYLQUINOLIN-2(1H)-ONE, Pol polyprotein, Reverse transcriptase, ...
Authors:Ren, J, Hopkins, A.L, Stuart, D.I, Stammers, D.K.
Deposit date:2004-06-09
Release date:2004-12-07
Last modified:2022-12-21
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase with improved drug resistance properties. 2.
J.Med.Chem., 47, 2004
1TMH
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MODULAR MUTAGENESIS OF A TIM-BARREL ENZYME: THE CRYSTAL STRUCTURE OF A CHIMERIC E. COLI TIM HAVING THE EIGHTH (BETA-ALPHA)-UNIT REPLACED BY THE EQUIVALENT UNIT OF CHICKEN TIM
Descriptor: SULFATE ION, TRIOSEPHOSPHATE ISOMERASE
Authors:Radha Kishan, K.V, Zeelen, J.Ph, Wierenga, R.K.
Deposit date:1994-03-22
Release date:1994-06-22
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Modular mutagenesis of a TIM-barrel enzyme: the crystal structure of a chimeric E. coli TIM having the eighth beta alpha-unit replaced by the equivalent unit of chicken TIM.
Protein Eng., 7, 1994
1TCF
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BU of 1tcf by Molmil
CRYSTAL STRUCTURE OF CALCIUM-SATURATED RABBIT SKELETAL TROPONIN C
Descriptor: CALCIUM ION, TROPONIN C
Authors:Soman, J, Phillips Jr, G.N.
Deposit date:1998-03-04
Release date:1998-05-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Conformational variation of calcium-bound troponin C.
Proteins, 37, 1999
1TCX
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BU of 1tcx by Molmil
HIV TRIPLE MUTANT PROTEASE COMPLEXED WITH INHIBITOR SB203386
Descriptor: (2R,4S,5S,1'S)-2-PHENYLMETHYL-4-HYDROXY-5-(TERT-BUTOXYCARBONYL)AMINO-6-PHENYL HEXANOYL-N-(1'-IMIDAZO-2-YL)-2'-METHYLPROPANAMIDE, HIV PROTEASE
Authors:Hoog, S.S, Abdel-Meguid, S.S.
Deposit date:1996-06-05
Release date:1996-12-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Human immunodeficiency virus protease ligand specificity conferred by residues outside of the active site cavity.
Biochemistry, 35, 1996
1TJS
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E. COLI THYMIDYLATE SYNTHASE
Descriptor: PHOSPHATE ION, THYMIDYLATE SYNTHASE
Authors:Stout, T.J, Sage, C.R, Stroud, R.M.
Deposit date:1997-06-27
Release date:1998-07-01
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The additivity of substrate fragments in enzyme-ligand binding.
Structure, 6, 1998
1TDU
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BU of 1tdu by Molmil
E. COLI THYMIDYLATE SYNTHASE IN COMPLEX WITH CB3717 AND 2'-DEOXYURIDINE (DURD)
Descriptor: 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, 2'-DEOXYURIDINE, PHOSPHATE ION, ...
Authors:Stout, T.J, Sage, C.R, Stroud, R.M.
Deposit date:1997-06-25
Release date:1998-07-01
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The additivity of substrate fragments in enzyme-ligand binding.
Structure, 6, 1998
1TEH
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BU of 1teh by Molmil
STRUCTURE OF HUMAN LIVER CHICHI ALCOHOL DEHYDROGENASE (A GLUTATHIONE-DEPENDENT FORMALDEHYDE DEHYDROGENASE)
Descriptor: HUMAN CHICHI ALCOHOL DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ZINC ION
Authors:Yang, Z.-N, Hurley, T.D.
Deposit date:1996-02-05
Release date:1996-12-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of human chi chi alcohol dehydrogenase: a glutathione-dependent formaldehyde dehydrogenase.
J.Mol.Biol., 265, 1997
1SRY
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BU of 1sry by Molmil
REFINED CRYSTAL STRUCTURE OF THE SERYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS AT 2.5 ANGSTROMS RESOLUTION
Descriptor: SERYL-tRNA SYNTHETASE
Authors:Fujinaga, M, Berthet-Colominas, C, Cusack, S.
Deposit date:1993-08-10
Release date:1994-01-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Refined crystal structure of the seryl-tRNA synthetase from Thermus thermophilus at 2.5 A resolution.
J.Mol.Biol., 234, 1993
1TEN
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BU of 1ten by Molmil
STRUCTURE OF A FIBRONECTIN TYPE III DOMAIN FROM TENASCIN PHASED BY MAD ANALYSIS OF THE SELENOMETHIONYL PROTEIN
Descriptor: TENASCIN
Authors:Leahy, D.J, Hendrickson, W.A, Aukhil, I, Erickson, H.P.
Deposit date:1992-08-28
Release date:1993-10-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of a fibronectin type III domain from tenascin phased by MAD analysis of the selenomethionyl protein.
Science, 258, 1992
1V8W
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Crystal structure analysis of the ADP-ribose pyrophosphatase of E82Q mutant, complexed with SO4 and Zn
Descriptor: ADP-ribose pyrophosphatase, SULFATE ION, ZINC ION
Authors:Yoshiba, S, Ooga, T, Nakagawa, N, Shibata, T, Inoue, Y, Yokoyama, S, Kuramitsu, S, Masui, R, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2004-01-15
Release date:2004-10-19
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Structural insights into the Thermus thermophilus ADP-ribose pyrophosphatase mechanism via crystal structures with the bound substrate and metal
J.Biol.Chem., 279, 2004
1UVQ
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Crystal structure of HLA-DQ0602 in complex with a hypocretin peptide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, GLYCINE, ...
Authors:Siebold, C, Hansen, B.E, Wyer, J.R, Harlos, K, Esnouf, R.E, Svejgaard, A, Bell, J.I, Strominger, J.L, Jones, E.Y, Fugger, L.
Deposit date:2004-01-22
Release date:2004-02-05
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of Hla-Dq0602 that Protects Against Type 1 Diabetes and Confers Strong Susceptibility to Narcolepsy
Proc.Natl.Acad.Sci.USA, 101, 2004
1UWF
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1.7 A resolution structure of the receptor binding domain of the FimH adhesin from uropathogenic E. coli
Descriptor: FIMH PROTEIN, GLYCEROL, butyl alpha-D-mannopyranoside
Authors:Bouckaert, J, Berglund, J, Genst, E.D, Cools, L, Hung, C.-S, Wuhrer, M, Zavialov, A, Langermann, S, Hultgren, S, Wyns, L, Oscarson, S, Knight, S.D, De Greve, H.
Deposit date:2004-02-05
Release date:2005-02-16
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Receptor Binding Studies Disclose a Novel Class of High-Affinity Inhibitors of the Escherichia Coli Fimh Adhesin.
Mol.Microbiol., 55, 2005
1UWM
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reduced ferredoxin 6 from Rhodobacter capsulatus
Descriptor: FE2/S2 (INORGANIC) CLUSTER, FERREDOXIN VI
Authors:Sainz, G, Jakoncic, J, Sieker, L.C, Stojanoff, V, Sanishvili, N, Asso, M, Bertrand, P, Armengaud, J, Jouanneau, Y.
Deposit date:2004-02-05
Release date:2006-01-18
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of a [2Fe-2S] Ferredoxin from Rhodobacter Capsulatus Likely Involved in Fe-S Cluster Biogenesis and Conformational Changes Observed Upon Reduction.
J.Biol.Inorg.Chem., 11, 2006
1UN6
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THE CRYSTAL STRUCTURE OF A ZINC FINGER - RNA COMPLEX REVEALS TWO MODES OF MOLECULAR RECOGNITION
Descriptor: 5S RIBOSOMAL RNA, MAGNESIUM ION, TRANSCRIPTION FACTOR IIIA, ...
Authors:Lu, D, Searles, M.A, Klug, A.
Deposit date:2003-09-04
Release date:2003-11-20
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal Structure of a Zinc-Finger-RNA Complex Reveals Two Modes of Molecular Recognition
Nature, 426, 2003
1UYT
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Acetyl-CoA carboxylase carboxyltransferase domain
Descriptor: ACETYL-COA CARBOXYLASE
Authors:Zhang, H, Tweel, B, Tong, L.
Deposit date:2004-03-02
Release date:2004-03-29
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular Basis for the Inhibition of the Carboxyltransferase Domain of Acetyl-Coenzyme-A Carboxylase by Haloxyfop and Diclofop.
Proc.Natl.Acad.Sci.USA, 101, 2004

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数据于2024-08-21公开中

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