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5USV	Insulin with proline analog AzeP at position B28 in the T2 state Descriptor: Insulin Chain A, Insulin Chain B, SODIUM ION Authors: Lieblich, S.A, Fang, K.Y, Tirrell, D.A. Deposit date: 2017-02-14 Release date: 2018-02-21 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Insulin with proline analog AzeP at position B28 in the T2 state To Be Published
5UOZ	Insulin with proline analog FyP at position B28 in the T2 state Descriptor: Insulin Chain A, Insulin Chain B Authors: Lieblich, S.A, Fang, K.Y, Tirrell, D.A. Deposit date: 2017-02-01 Release date: 2018-02-07 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.17463875 Å) Cite: Insulin with proline analog FyP at position B28 in the T2 state To Be Published
5UQA	Insulin with proline analog FzP at position B28 in the R6 state Descriptor: ACETONE, CHLORIDE ION, GLYCEROL, ... Authors: Lieblich, S.A, Fang, K.Y, Tirrell, D.A. Deposit date: 2017-02-07 Release date: 2018-02-21 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.31000245 Å) Cite: Insulin with proline analog FzP at position B28 in the R6 state To Be Published
5UDP	High resolution x-ray crystal structure of synthetic insulin lispro Descriptor: CHLORIDE ION, Insulin Lispro A chain, Insulin Lispro B chain, ... Authors: Mandal, K, Dhayalan, B, Kent, S.B.H. Deposit date: 2016-12-28 Release date: 2017-01-11 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.348 Å) Cite: Scope and Limitations of Fmoc Chemistry SPPS-Based Approaches to the Total Synthesis of Insulin Lispro via Ester Insulin. Chemistry, 23, 2017
5UU3	Insulin with proline analog DfP at position B28 in the R6 state Descriptor: CHLORIDE ION, Insulin, chain A, ... Authors: Lieblich, S.A, Fang, K.Y, Tirrell, D.A. Deposit date: 2017-02-16 Release date: 2018-02-21 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Insulin with proline analog DfP at position B28 in the R6 state To Be Published
1G7B	1.3 A STRUCTURE OF T3R3 HUMAN INSULIN AT 100 K Descriptor: ACETONE, CHLORIDE ION, GLYCEROL, ... Authors: Smith, G.D, Pangborn, W.A, Blessing, R.H. Deposit date: 2000-11-09 Release date: 2001-08-03 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Phase changes in T(3)R(3)(f) human insulin: temperature or pressure induced? Acta Crystallogr.,Sect.D, 57, 2001
1FUB	FIRST PROTEIN STRUCTURE DETERMINED FROM X-RAY POWDER DIFFRACTION DATA Descriptor: CHLORIDE ION, INSULIN, A CHAIN, ... Authors: Von Dreele, R.B, Stephens, P.W, Blessing, R.H, Smith, G.D. Deposit date: 2000-09-14 Release date: 2000-10-16 Last modified: 2018-10-03 Method: POWDER DIFFRACTION Cite: The first protein crystal structure determined from high-resolution X-ray powder diffraction data: a variant of T3R3 human insulin-zinc complex produced by grinding. Acta Crystallogr.,Sect.D, 56, 2000
5VIZ	X-Ray structure of Insulin Glargine Descriptor: Insulin, chain alpha, chain beta Authors: Reyes-Grajeda, J.P, Romero, A. Deposit date: 2017-04-17 Release date: 2017-10-18 Method: X-RAY DIFFRACTION (1.7 Å) Cite: X-Ray structure of Insulin Glargine To Be Published
5UU4	Insulin with proline analog ThioP at position B28 in the R6 state Descriptor: CHLORIDE ION, Insulin A Chain, Insulin B Chain, ... Authors: Lieblich, S.A, Fang, K.Y, Tirrell, D.A. Deposit date: 2017-02-16 Release date: 2018-02-21 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.973 Å) Cite: Insulin with proline analog ThioP at position B28 in the R6 state To Be Published
5USS	Insulin with proline analog PiP at position B28 in the R6 state Descriptor: CHLORIDE ION, Insulin Chain A, Insulin Chain B, ... Authors: Lieblich, S.A, Fang, K.Y, Tirrell, D.A. Deposit date: 2017-02-13 Release date: 2018-02-21 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.061 Å) Cite: Insulin with proline analog PiP at position B28 in the R6 state To Be Published
5UU2	Insulin with proline analog ThioP at position B28 in the T2 state Descriptor: Insulin Chain A, Insulin Chain B Authors: Lieblich, S.A, Fang, K.Y, Tirrell, D.A. Deposit date: 2017-02-15 Release date: 2018-02-21 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.223 Å) Cite: Insulin with proline analog ThioP at position B28 in the T2 state To Be Published
1GZY	Human Insulin-like growth factor; In-house data Descriptor: INSULIN-LIKE GROWTH FACTOR I, N-DODECYL-N,N-DIMETHYL-3-AMMONIO-1-PROPANESULFONATE Authors: Brzozowski, A.M, Dodson, E.J, Dodson, G.G, Murshudov, G, Verma, C, Turkenburg, J.P, De Bree, F.M, Dauter, Z. Deposit date: 2002-06-10 Release date: 2002-07-25 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.54 Å) Cite: Structural Origins of the Functional Divergence of Human Insulin-Like Growth Factor-I and Insulin Biochemistry, 41, 2002
5URU	Insulin with proline analog DhP at position B28 in the R6 state Descriptor: CHLORIDE ION, Insulin Chain A, Insulin Chain B, ... Authors: Lieblich, S.A, Fang, K.Y, Tirrell, D.A. Deposit date: 2017-02-13 Release date: 2018-02-21 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.41 Å) Cite: Insulin with proline analog DhP at position B28 in the R6 state To Be Published
1FU2	FIRST PROTEIN STRUCTURE DETERMINED FROM X-RAY POWDER DIFFRACTION DATA Descriptor: CHLORIDE ION, INSULIN, A CHAIN, ... Authors: Von Dreele, R.B, Stephens, P.W, Blessing, R.H, Smith, G.D. Deposit date: 2000-09-13 Release date: 2000-10-16 Last modified: 2018-10-03 Method: POWDER DIFFRACTION Cite: The first protein crystal structure determined from high-resolution X-ray powder diffraction data: a variant of T3R3 human insulin-zinc complex produced by grinding. Acta Crystallogr.,Sect.D, 56, 2000
1G7A	1.2 A structure of T3R3 human insulin at 100 K Descriptor: ACETONE, CHLORIDE ION, GLYCEROL, ... Authors: Smith, G.D, Pangborn, W.A, Blessing, R.H. Deposit date: 2000-11-09 Release date: 2001-08-03 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (1.2 Å) Cite: Phase changes in T(3)R(3)(f) human insulin: temperature or pressure induced? Acta Crystallogr.,Sect.D, 57, 2001
1GUJ	Insulin at pH 2: structural analysis of the conditions promoting insulin fibre formation. Descriptor: INSULIN, SULFATE ION Authors: Whittingham, J.L, Scott, D.J, Chance, K, Wilson, A, Finch, J, Brange, J, Dodson, G.G. Deposit date: 2002-01-28 Release date: 2002-03-08 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.62 Å) Cite: Insulin at Ph2: Structural Analysis of the Conditions Promoting Insulin Fibre Formation J.Mol.Biol., 318, 2002
1GZZ	Human Insulin-like growth factor; Hamburg data Descriptor: INSULIN-LIKE GROWTH FACTOR I, N-DODECYL-N,N-DIMETHYL-3-AMMONIO-1-PROPANESULFONATE Authors: Brzozowski, A.M, Dodson, E.J, Dodson, G.G, Murshudov, G, Verma, C, Turkenburg, J.P, De Bree, F.M, Dauter, Z. Deposit date: 2002-06-10 Release date: 2002-07-25 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural Origins of the Functional Divergence of Human Insulin-Like Growth Factor-I and Insulin Biochemistry, 41, 2002
1DPH	CONFORMATIONAL CHANGES IN CUBIC INSULIN CRYSTALS IN THE PH RANGE 7-11 Descriptor: 1,2-DICHLOROETHANE, INSULIN A CHAIN (PH 11), INSULIN B CHAIN (PH 11), ... Authors: Gursky, O, Badger, J, Li, Y, Caspar, D.L.D. Deposit date: 1992-10-30 Release date: 1993-01-15 Last modified: 2017-11-29 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Conformational changes in cubic insulin crystals in the pH range 7-11. Biophys.J., 63, 1992
5WDM	An ultra-stable single-chain insulin analog resists thermal inactivation and exhibits biological signaling duration equivalent to the native protein Descriptor: Single-chain insulin analog Authors: Yee, V.C, Aldabbagh, K, Peng, Y. Deposit date: 2017-07-05 Release date: 2017-11-15 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.803 Å) Cite: An ultra-stable single-chain insulin analog resists thermal inactivation and exhibits biological signaling duration equivalent to the native protein. J. Biol. Chem., 293, 2018
1GZR	Human Insulin-like growth factor; ESRF data Descriptor: INSULIN-LIKE GROWTH FACTOR I, N-DODECYL-N,N-DIMETHYL-3-AMMONIO-1-PROPANESULFONATE Authors: Brzozowski, A.M, Dodson, E.J, Dodson, G.G, Murshudov, G, Verma, C, Turkenburg, J.P, De Bree, F.M, Dauter, Z. Deposit date: 2002-05-28 Release date: 2002-07-25 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural Origins of the Functional Divergence of Human Insulin-Like Growth Factor-I and Insulin Biochemistry, 41, 2002
1EV3	Structure of the rhombohedral form of the M-cresol/insulin R6 hexamer Descriptor: CHLORIDE ION, INSULIN, M-CRESOL, ... Authors: Smith, G.D, Ciszak, E, Magrum, L.A, Pangborn, W.A, Blessing, R.H. Deposit date: 2000-04-19 Release date: 2000-12-04 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.78 Å) Cite: R6 hexameric insulin complexed with m-cresol or resorcinol. Acta Crystallogr.,Sect.D, 56, 2000
1H02	Human Insulin-like growth factor; SRS Daresbury data Descriptor: INSULIN-LIKE GROWTH FACTOR I, N-DODECYL-N,N-DIMETHYL-3-AMMONIO-1-PROPANESULFONATE Authors: Brzozowski, A.M, Dodson, E.J, Dodson, G.G, Murshudov, G, Verma, C, Turkenburg, J.P, De Bree, F.M, Dauter, Z. Deposit date: 2002-06-11 Release date: 2002-07-25 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural Origins of the Functional Divergence of Human Insulin-Like Growth Factor-I and Insulin Biochemistry, 41, 2002
7QAC	The T2 structure of polycrystalline cubic human insulin Descriptor: Insulin A chain, Insulin B chain Authors: Karavassili, F, Triandafillidis, D.P, Valmas, A, Spiliopoulou, M, Fili, S, Kontou, P, Bowler, M.W, Von Dreele, R.B, Fitch, A, Margiolaki, I. Deposit date: 2021-11-16 Release date: 2023-06-21 Last modified: 2024-10-09 Method: POWDER DIFFRACTION (2.29 Å) Cite: The T 2 structure of polycrystalline cubic human insulin. Acta Crystallogr D Struct Biol, 79, 2023
7RKD	X-Ray structure of Insulin Analog GLULISINE Descriptor: Insulin B chain analog, Insulin chain A, ZINC ION Authors: Reyes-Grajeda, J.P. Deposit date: 2021-07-22 Release date: 2022-07-27 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.25 Å) Cite: Insulin ANALOGS To Be Published
7S4Y	Serial Macromolecular Crystallography at ALBA Synchrotron Light Source - Insulin Descriptor: CHLORIDE ION, Insulin A chain, Insulin B chain, ... Authors: Martin-Garcia, J.M, Botha, S, Hu, H, Jernigan, R, Castellvi, A, Lisova, S, Gil, F, Calisto, B, Crespo, I, Roy-Chowdbury, S, Grieco, A, Ketawala, G, Weierstall, U, Spence, J, Fromme, P, Zatsepin, N, Boer, R, Carpena, X. Deposit date: 2021-09-09 Release date: 2021-10-27 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.71 Å) Cite: Serial macromolecular crystallography at ALBA Synchrotron Light Source. J.Synchrotron Radiat., 29, 2022

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